Best TWAS P=4.15e-10 · Best GWAS P=1.81e-08 conditioned to 0.563
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRMT7 | 0.23 | 0.19 | bslmm | 319 | 0.19 | 2.2e-22 | 5.3 | 5.5 | 3.2e-08 | 0.85 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Lung | NFATC3 | 0.04 | 0.01 | lasso | 4 | 0.01 | 4.1e-02 | -5.0 | 5.3 | 1.2e-07 | 0.27 | 0.06 | 0.81 | FALSE |
| 3 | GTEx | Testis | NFATC3 | 0.23 | 0.16 | lasso | 7 | 0.17 | 6.0e-08 | 4.1 | 5.1 | 2.9e-07 | 0.78 | 0.59 | 0.38 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PRMT7 | 0.19 | 0.14 | enet | 5 | 0.15 | 6.9e-17 | 5.3 | 6.2 | 4.2e-10 | 0.93 | 0.01 | 0.99 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | PRMT7 | 0.05 | 0.05 | lasso | 1 | 0.04 | 5.3e-06 | 5.3 | 5.3 | 1.4e-07 | 0.86 | 0.02 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | PRMT7 | 0.27 | 0.15 | blup | 58 | 0.18 | 9.1e-18 | 4.8 | 5.2 | 2.2e-07 | 0.81 | 0.03 | 0.97 | FALSE |