Best TWAS P=1.86e-24 · Best GWAS P=3.13e-99 conditioned to 4.21e-51
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FTO | 0.11 | 0.00 | bslmm | 739 | 0.02 | 1.6e-03 | -0.15 | -9.6 | 7.3e-22 | 0.38 | 0.09 | 0.55 | TRUE |
| 2 | GTEx | Testis | AKTIP | 0.19 | 0.00 | enet | 26 | 0.00 | 1.9e-01 | -0.89 | -10.2 | 1.9e-24 | 0.51 | 0.03 | 0.40 | TRUE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | FTO | 0.27 | 0.16 | enet | 13 | 0.14 | 6.7e-05 | 2.84 | -8.3 | 7.0e-17 | 0.33 | 0.11 | 0.32 | TRUE |