Hub : Genes

NFATC3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0480 0.0260 4.6e-04 0.023 0.024 0.009 0.020 0.004 6.5e-04 6.1e-04 2.6e-02 1.6e-03 1.0e-01
2 GTEx Adipose Subcutaneous 0.1090 0.0470 2.9e-04 0.035 NA 0.026 NA 0.034 7.2e-04 NA 2.9e-03 NA 7.9e-04
3 GTEx Adipose Visceral Omentum 0.0710 0.0390 9.4e-03 0.020 NA 0.006 NA 0.001 3.1e-02 NA 1.4e-01 NA 2.8e-01
4 GTEx Artery Aorta 0.1590 0.0570 3.1e-06 0.170 NA 0.163 NA 0.164 1.1e-09 NA 2.7e-09 NA 2.4e-09
5 GTEx Artery Coronary 0.1100 0.0550 4.2e-03 0.080 NA 0.013 NA 0.034 1.2e-03 NA 1.1e-01 NA 2.7e-02
6 GTEx Artery Tibial 0.1308 0.0548 6.2e-06 0.149 NA 0.161 NA 0.158 9.6e-12 NA 1.2e-12 NA 2.2e-12
7 GTEx Colon Transverse 0.2100 0.0620 8.1e-07 0.110 NA 0.135 NA 0.121 6.4e-06 NA 5.9e-07 NA 2.2e-06
8 GTEx Esophagus Gastroesophageal Junction 0.1150 0.0600 1.0e-03 0.042 NA 0.073 NA 0.078 1.2e-02 NA 1.3e-03 NA 8.8e-04
9 GTEx Esophagus Mucosa 0.1190 0.0490 5.4e-05 0.031 NA 0.054 NA 0.012 3.6e-03 NA 1.6e-04 NA 4.9e-02
10 GTEx Esophagus Muscularis 0.0670 0.0380 2.5e-03 0.074 NA 0.022 NA 0.000 2.8e-05 NA 1.7e-02 NA 3.2e-01
11 GTEx Lung 0.0404 0.0214 9.7e-03 0.012 NA 0.002 NA 0.012 4.0e-02 NA 2.0e-01 NA 4.1e-02
12 GTEx Nerve Tibial 0.0827 0.0322 2.2e-05 0.062 NA 0.053 NA 0.062 3.3e-05 NA 1.3e-04 NA 3.2e-05
13 GTEx Skin Sun Exposed Lower leg 0.0600 0.0290 3.1e-03 0.039 NA 0.049 NA 0.047 3.2e-04 NA 6.6e-05 NA 8.3e-05
14 GTEx Spleen 0.2930 0.1030 1.1e-04 0.299 NA 0.110 NA 0.254 2.2e-08 NA 9.6e-04 NA 3.3e-07
15 GTEx Testis 0.2340 0.0650 4.7e-08 0.158 NA 0.151 NA 0.169 1.6e-07 NA 3.1e-07 NA 6.0e-08
16 GTEx Thyroid 0.1230 0.0460 4.0e-07 0.130 NA 0.101 NA 0.107 3.6e-10 NA 3.9e-08 NA 1.4e-08
17 METSIM Adipose 0.0272 0.0160 1.3e-02 -0.002 0.000 -0.002 -0.001 -0.001 7.6e-01 3.4e-01 7.0e-01 4.8e-01 6.7e-01
18 YFS Blood 0.1297 0.0383 0.0e+00 0.071 0.082 0.100 0.085 0.089 4.8e-22 1.4e-25 7.1e-31 1.7e-26 1.7e-27
19 TCGA Bladder Urothelial Carcinoma 0.1760 0.0720 2.0e-05 0.085 0.064 0.069 NA 0.075 1.1e-07 4.2e-06 1.8e-06 NA 6.1e-07
20 TCGA Breast Invasive Carcinoma 0.0541 0.0320 2.3e-03 0.007 0.007 0.007 NA 0.006 1.2e-02 1.2e-02 1.0e-02 NA 1.7e-02
21 TCGA Colon Adenocarcinoma 0.2180 0.0830 9.7e-05 0.047 0.047 0.031 NA 0.056 1.0e-03 9.6e-04 6.6e-03 NA 3.6e-04
22 TCGA Kidney Renal Clear Cell Carcinoma 0.1119 0.0562 6.0e-04 0.041 0.026 0.039 NA 0.033 2.0e-05 5.8e-04 2.8e-05 NA 1.1e-04
23 TCGA Brain Lower Grade Glioma 0.2283 0.1008 1.1e-06 0.049 0.035 0.043 NA 0.064 2.7e-06 7.0e-05 9.9e-06 NA 8.5e-08
24 TCGA Pancreatic Adenocarcinoma 0.2280 0.0920 2.1e-03 0.049 0.054 0.061 NA 0.015 4.0e-03 2.7e-03 1.5e-03 NA 7.4e-02
25 TCGA Pheochromocytoma and Paraganglioma 0.2630 0.1000 6.6e-04 0.088 0.094 0.127 NA 0.115 2.4e-04 1.4e-04 9.8e-06 NA 2.6e-05
26 TCGA Prostate Adenocarcinoma 0.1835 0.0671 3.5e-07 0.045 0.061 0.055 NA 0.056 1.5e-05 6.0e-07 1.9e-06 NA 1.7e-06
27 TCGA Soft Tissue Sarcoma 0.2810 0.0870 8.3e-07 0.107 0.121 0.139 NA 0.122 6.8e-07 1.1e-07 1.3e-08 NA 1.1e-07
28 TCGA Testicular Germ Cell Tumors 0.4570 0.1110 1.1e-06 0.164 0.188 0.194 NA 0.197 2.1e-06 3.2e-07 2.0e-07 NA 1.7e-07
29 TCGA Thyroid Carcinoma 0.0870 0.0420 1.6e-03 0.021 0.016 0.020 NA 0.000 3.2e-03 9.3e-03 3.9e-03 NA 3.2e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
Bipolar Disorder (2018) 3.8 6.1 15.9 0.5 -2.9 -2.8 -1.4 0.0 -1.3 -3.2 -1.9 -2.1 -2.2 -2.3 -2.6 -3.1 -1.6 -1.2 -2.6 -4.0 0.6 -2.9 -1.9 -2.6 -2.4 -2.6 -3.3 -2.8 -3.0 -3.4 -2.7 -2.6
Bipolar Disorder or Schizophrenia 2.4 5.9 17.3 -1.2 -4.1 -3.0 -1.9 0.0 -1.1 -3.1 -2.8 -1.3 -2.3 -0.4 -3.0 -2.4 0.2 0.4 -2.9 -4.2 2.0 -3.2 -2.4 -2.0 -1.4 -1.7 -3.2 -2.2 -2.9 -3.1 -2.1 -2.5
Depressed Affect (Nagel 2018) 1.4 3.0 6.7 -1.5 1.2 1.6 1.0 -1.7 0.7 2.3 -0.2 1.8 1.4 2.3 1.6 1.7 2.6 2.1 1.6 1.2 1.7 1.2 1.0 2.1 2.2 2.2 1.6 2.1 1.8 2.1 1.8 1.6
Depression (Nagel 2018) 1.9 2.9 8.7 -2.1 0.8 1.1 1.3 -1.2 1.6 2.1 0.1 1.7 1.3 3.0 1.3 1.6 2.3 2.2 1.3 1.3 1.6 0.9 1.0 1.8 1.9 1.8 2.1 1.8 2.0 2.2 1.6 1.5
Intelligence (Savage-Jansen 2018) 2.0 6.1 22.5 3.7 -0.4 -0.6 0.3 -0.5 -1.4 -1.6 1.7 -2.7 -1.2 -4.7 -1.2 -2.9 -3.6 -4.2 -1.1 -1.0 -3.2 -0.5 0.4 -3.2 -4.0 -3.6 -2.0 -3.0 -1.6 -2.4 -2.6 -1.8
Neuroticism (Nagel 2018) 2.0 4.6 13.3 -1.9 1.2 1.4 1.5 -1.4 1.3 2.6 -0.1 2.5 1.6 3.6 1.8 2.5 3.3 2.7 1.9 1.4 2.0 1.1 1.2 2.7 2.9 2.7 1.7 2.6 2.4 2.5 2.2 1.9
Schizophrenia (2018) 1.0 2.0 8.5 -1.9 -2.9 -1.6 -1.2 0.0 -0.3 -1.4 -1.9 -0.1 -1.3 1.4 -1.8 -0.6 1.2 1.5 -1.6 -2.1 2.3 -1.8 -1.5 -0.5 0.2 -0.2 -1.5 -0.6 -1.4 -1.2 -0.5 -1.1
Schizophrenia vs Biploar Disorder 1.6 2.1 9.2 -3.0 -1.3 -0.9 -2.2 0.0 -2.0 -0.2 -2.6 -0.6 -1.6 1.3 -1.8 -0.1 0.4 2.5 -1.5 -0.5 2.4 -1.5 -1.3 -0.6 -0.1 -0.4 0.8 -0.6 -1.1 -0.8 -0.8 -1.1
Worry (Nagel 2018) 1.7 3.5 12.7 -1.1 0.9 1.0 1.8 -1.2 1.5 2.2 1.0 2.1 1.4 3.6 1.6 2.2 2.8 2.1 1.7 1.1 1.6 0.9 0.8 2.5 2.7 2.6 0.6 2.4 1.9 1.8 2.0 1.7
Alzheimer’s Disease (in mother) 0.3 0.4 2.1 -1.4 0.1 -0.3 -0.1 -0.7 -0.3 0.1 0.4 -0.1 -0.2 1.1 -0.2 0.7 0.3 1.4 -0.2 1.3 0.5 -0.1 -0.3 -0.1 0.0 0.0 1.4 0.0 0.2 0.5 -0.1 -0.1
Alzheimer’s Disease (in father) 0.3 0.3 1.1 0.8 0.0 -0.0 0.9 -1.0 0.6 1.0 -0.5 0.3 0.5 0.9 0.2 0.9 0.8 -0.4 0.5 0.0 -0.1 0.2 -0.0 0.3 0.4 0.4 -0.1 0.3 0.6 0.6 0.3 0.3
Alzheimer’s Disease (including proxy) 0.6 0.8 3.4 -0.4 0.7 0.3 0.7 -1.9 0.3 1.2 0.3 0.7 0.8 1.5 0.4 1.4 1.2 1.0 0.5 1.6 0.1 0.5 0.2 0.5 0.6 0.6 1.4 0.6 0.9 1.2 0.6 0.5
Crohns Disease (2017) 0.7 1.6 8.2 1.8 0.2 -0.9 -1.0 -0.4 -1.7 -0.9 1.1 -1.9 -1.3 -1.7 -0.8 -1.0 -2.9 -1.8 -0.6 0.3 -1.2 -0.6 0.5 -1.2 -1.6 -1.4 -1.1 -1.1 -0.8 -1.0 -1.3 -0.9
Irritable Bowel Disease (IBD) 0.2 0.4 3.0 0.5 0.2 -0.2 -0.3 -0.3 -0.6 -1.5 1.7 -0.4 -0.8 -0.1 0.0 0.4 -1.1 -0.2 0.2 1.4 -0.8 -0.4 0.7 0.1 -0.4 -0.3 -0.3 -0.1 0.1 0.1 -0.6 -0.2
Ulcerative Colitis (UC) 0.3 0.6 4.0 -1.3 -0.2 0.3 0.6 0.3 1.1 -2.0 1.6 0.8 -0.2 0.9 0.3 0.7 0.8 1.4 0.3 1.2 0.1 -0.5 0.1 0.6 0.3 0.3 0.3 0.4 0.4 0.6 -0.1 0.0
Major Depression (MDD) 3.2 3.9 8.2 -0.1 -2.2 -2.6 -0.8 1.6 -1.6 -2.1 -0.7 -2.3 -1.9 -1.7 -2.4 -2.4 -2.0 -0.8 -2.2 -2.6 0.3 -1.7 -2.9 -2.5 -1.9 -1.8 -2.1 -2.0 -2.7 -2.3 -1.9 -1.9
Reaction Time 0.5 1.0 2.5 -0.3 -1.3 -1.1 0.1 0.4 -0.1 0.2 -0.1 -1.4 -1.0 -1.6 -0.9 -1.4 -1.1 0.1 -1.1 -0.9 -0.1 -1.2 -0.7 -0.8 -1.0 -1.2 -0.7 -1.2 -1.0 -1.5 -1.1 -1.1
Verbal and Numeric Reasoning (VNR) 1.0 2.5 8.8 2.6 -0.1 -0.1 0.4 -0.2 -0.8 -1.0 0.9 -1.3 -0.3 -2.8 -0.7 -1.8 -2.3 -3.0 -0.8 -0.8 -2.5 0.2 0.0 -2.4 -2.5 -2.1 -1.1 -1.8 -1.2 -1.2 -1.5 -0.9
Breast Cancer 1.1 2.6 8.4 1.7 1.4 2.0 2.3 -2.9 1.5 2.2 1.2 1.1 1.8 0.5 2.1 1.2 0.5 -1.1 1.9 1.3 -2.9 2.1 0.9 1.2 0.9 1.2 0.6 1.4 1.3 1.6 1.4 1.7
Ovarian Cancer 7.1 9.4 18.8 2.3 4.0 4.3 2.7 -3.6 3.0 2.6 2.6 3.1 3.9 1.6 3.7 3.3 2.0 -1.3 3.6 3.8 -2.3 4.1 3.3 2.5 2.4 2.7 1.9 3.0 3.0 3.1 3.2 3.6
Prostate Cancer 4.1 5.7 9.8 0.2 3.1 2.4 0.8 -1.9 0.4 1.4 1.9 2.7 2.8 1.3 2.9 2.8 2.3 0.5 2.9 3.0 -0.5 2.8 2.9 2.6 2.4 2.6 2.8 2.7 3.0 3.1 2.6 2.7
Age at First Birth 3.0 4.4 8.6 2.5 -1.5 -1.4 0.1 0.4 -0.4 -1.7 0.1 -1.9 -1.0 -2.9 -1.5 -2.5 -2.7 -2.6 -1.7 -2.1 -2.1 -1.4 -1.6 -2.9 -2.9 -2.6 -2.6 -2.5 -2.7 -2.8 -2.5 -2.1
Bipolar Disorder (2011) 7.7 7.5 24.5 1.1 -4.0 -3.5 -1.7 0.0 -1.9 -2.9 -2.4 -3.3 -3.2 -2.6 0.0 -3.9 -2.8 -1.8 -3.1 -4.3 -0.2 -3.4 0.0 0.0 0.0 -2.6 -5.0 -2.9 -3.9 -4.3 0.0 0.0
Body Mass Index (BMI) (2010) 3.3 4.5 8.9 0.4 -1.9 -2.3 -2.4 0.9 -2.6 -1.7 -1.8 -2.3 -1.9 -2.4 -2.4 -2.8 -1.7 -0.9 -2.3 -2.8 0.2 -2.0 -2.2 -2.4 -2.3 -2.3 -2.1 -2.4 -3.0 -2.7 -2.3 0.0
Coronary Artery Disease (CAD) 0.3 0.4 1.4 0.7 0.8 0.5 1.2 0.0 0.7 0.3 1.1 0.3 0.9 -0.5 0.7 0.7 -0.3 -1.0 0.5 0.4 -1.0 0.9 0.0 0.0 0.0 0.3 -0.3 0.4 0.0 0.6 0.0 0.0
Crohns Disease (2012) 1.1 1.8 4.8 0.5 -0.6 -1.0 -1.4 0.0 -1.3 -2.0 0.7 -1.4 -1.2 -2.2 -1.4 -1.4 -2.0 -0.9 -1.4 -0.6 -1.0 -0.8 0.0 -1.8 -1.8 -1.6 -1.0 -1.5 -1.7 -1.4 -1.5 -1.2
Mean Putamen Volume 0.3 0.4 2.2 1.5 -0.2 -0.3 -0.4 -0.9 -0.4 -0.0 0.4 0.1 -0.1 1.2 0.2 0.5 0.2 -1.2 0.5 -0.1 -0.3 0.0 0.9 0.4 0.3 0.3 -1.5 0.2 0.5 -0.2 0.3 0.2
Fasting Glucose 2.2 2.6 9.9 2.7 2.8 1.6 1.8 -2.9 1.3 1.9 1.5 1.1 1.9 -1.3 1.8 0.6 -0.6 -2.2 1.5 2.0 -3.1 0.6 1.5 0.7 -0.2 -0.3 -0.1 0.1 1.3 0.8 -0.2 1.0
HbA1C 1.4 1.5 5.7 0.5 -1.7 -0.6 -0.1 1.3 0.2 -1.1 -0.3 -1.3 -0.5 -2.4 -1.0 -1.5 -0.9 -1.3 -1.2 -1.8 0.1 1.5 -1.9 -2.3 -1.2 -0.5 -0.5 -0.7 -2.1 -0.8 0.2 -0.6
HDL Cholesterol 9.1 15.2 95.1 -9.8 -5.3 -4.0 -2.1 2.6 -1.9 -2.0 -4.1 -1.2 -3.3 3.4 -3.8 -0.6 2.2 9.7 -3.5 -0.4 7.8 -4.8 -4.1 -0.2 0.5 -0.5 3.2 -1.3 -1.1 -0.9 -1.7 0.0
LDL Cholesterol 0.5 0.8 1.7 0.2 0.4 0.4 1.0 -0.6 0.9 1.3 0.8 0.7 0.8 0.9 1.0 0.8 1.0 0.3 1.0 -0.0 0.3 0.7 0.9 1.2 1.2 1.1 0.7 1.1 1.3 1.1 1.0 0.0
Lupus 0.6 0.9 6.4 -2.0 -0.8 -0.7 -0.9 0.7 -1.0 1.0 0.3 -0.2 -0.6 0.8 -0.4 -0.1 0.7 2.5 -0.3 -0.9 2.0 -1.3 -0.7 0.5 0.2 -0.0 0.8 -0.1 0.3 0.3 -0.5 -0.7
Neuroticism (2016) 1.8 2.5 6.9 -1.4 1.0 0.9 1.6 -1.1 1.3 1.4 0.7 1.9 1.4 2.5 1.4 1.9 2.6 2.2 1.4 1.1 1.4 0.8 0.6 1.8 1.9 2.0 1.4 1.8 1.6 2.0 1.4 1.2
Primary Biliary Cirrhosis 1.7 2.5 17.6 -4.2 -0.6 -0.9 -0.8 2.1 -0.4 -0.7 -0.7 0.2 -0.7 1.4 -1.0 0.6 1.2 4.2 -1.1 0.1 3.6 -1.1 -0.4 0.1 0.4 0.1 2.8 -0.1 0.1 0.2 -0.2 -0.7
Rheumatoid Arthritis 1.0 1.4 4.4 1.8 1.6 1.4 1.0 0.0 0.9 2.1 0.5 1.0 1.5 0.7 1.2 1.2 0.9 -0.7 1.4 0.8 -1.2 1.1 1.5 1.2 1.1 1.0 0.2 1.1 1.2 1.3 1.1 1.3
Schizophrenia (2014) 1.3 2.8 9.0 -2.9 -3.0 -1.7 -1.3 0.0 -0.3 -2.2 -2.3 -0.3 -1.5 1.3 -2.2 -0.5 1.0 2.1 -2.1 -2.1 3.0 -2.1 -1.8 -0.8 0.0 -0.4 -1.0 -0.9 -1.7 -1.5 -0.7 -1.4
Triglycerides 0.3 0.5 2.6 1.3 0.5 -0.2 -0.2 1.0 -0.0 -0.1 0.3 -0.6 -0.2 -1.6 0.2 -0.2 -0.7 -1.4 0.2 -1.1 -0.5 0.1 0.3 -0.4 -0.6 -0.4 -1.2 -0.3 -0.6 -0.7 -0.4 0.0
Type 2 Diabetes (T2D) (2012) 1.1 1.3 5.7 0.4 -1.1 -1.2 0.0 2.1 -0.4 -2.1 0.4 -0.8 -1.0 -0.8 -1.0 -1.4 -1.1 -1.6 -0.9 -0.9 -0.5 -0.9 -0.5 -1.2 -1.1 -1.0 -2.4 -1.0 -0.9 -1.3 -1.0 0.0
Ulcerative Colitis 0.5 0.7 2.2 -0.4 0.7 0.7 -0.1 0.0 0.2 -0.6 0.7 0.6 0.3 1.0 1.1 1.0 0.6 0.9 1.2 1.5 -0.4 0.2 1.2 1.5 1.0 0.8 0.6 1.0 1.4 1.1 0.6 0.7
Blood Eosinophil Count 5.0 38.3 72.4 -6.0 5.1 5.5 5.0 -2.2 5.8 1.9 4.1 8.1 5.5 7.9 5.8 8.5 8.1 6.5 5.5 7.6 2.7 4.9 4.2 7.0 7.4 7.1 7.0 6.9 6.5 7.3 6.5 6.0
Blood Platelet Count 0.2 2.3 21.1 -1.8 1.2 0.1 -1.8 0.4 -2.1 1.8 -2.2 -1.4 -0.1 -2.3 -0.6 -0.4 0.2 2.8 -0.4 -0.4 2.4 0.6 0.0 -0.6 -0.6 -0.6 4.6 -0.6 0.2 1.0 -0.2 -0.2
Blood Red Count 4.5 43.0 84.6 -6.4 -8.8 -8.7 -5.1 6.4 -5.1 -6.0 -8.3 -6.2 -7.5 -1.4 -8.6 -5.7 -1.2 4.4 -7.9 -7.4 9.2 -8.9 -7.3 -5.3 -4.2 -4.8 -1.9 -6.0 -6.7 -6.8 -6.4 -7.6
Blood White Count 0.8 6.0 20.4 -2.9 2.6 1.9 3.3 -1.3 2.4 0.5 4.5 2.7 2.5 2.0 2.5 2.9 2.0 2.8 1.7 3.6 0.5 2.4 0.9 1.8 2.0 2.0 3.8 2.1 1.9 2.6 2.2 2.0
Heel T-Score 0.9 7.4 33.5 2.1 -4.0 -2.7 2.6 1.7 2.9 -1.3 1.3 -1.3 -1.2 -0.7 -1.2 -4.2 -2.0 -2.7 -2.1 -5.8 -1.3 -3.4 -2.8 -1.5 -1.8 -2.0 -4.9 -2.2 -2.7 -3.5 -2.5 -2.6
BMI 2.8 16.4 35.9 -0.0 -3.6 -4.1 -4.3 2.5 -4.6 -4.9 -2.5 -4.8 -3.9 -6.0 -3.8 -5.2 -3.8 -1.4 -3.8 -4.6 -0.6 -3.6 -4.7 -4.3 -4.6 -4.5 -3.4 -4.5 -4.6 -4.0 -4.4 -4.3
Height 0.5 8.9 38.8 -4.4 2.5 -0.5 -3.2 -0.8 -5.0 -1.1 -0.7 -3.4 -2.2 -2.8 -2.1 0.6 -2.7 4.8 -2.0 4.6 4.5 -1.2 0.3 -2.7 -3.3 -2.8 6.2 -2.3 -1.5 -1.0 -3.0 -2.5
Waist Hip Ratio (WHR) 3.0 13.5 35.0 -2.2 4.8 4.6 3.1 -2.6 2.6 1.8 3.7 3.9 3.4 3.0 4.0 4.9 2.3 3.3 3.6 5.9 -0.2 4.3 3.3 3.0 2.9 3.2 5.7 3.6 3.9 4.4 3.5 3.8
Systolic Blood Pressure 0.6 3.1 9.6 1.6 -0.9 -0.8 -1.0 -0.5 -2.3 -1.6 -1.5 -2.1 -1.7 -1.6 -1.5 -1.6 -3.1 -1.6 -1.5 -0.6 0.0 -1.3 -0.8 -2.1 -2.3 -2.1 -2.2 -2.0 -2.4 -2.8 -2.0 -1.8
Smoking Status 0.2 0.5 2.9 -1.7 -0.3 0.3 -1.7 0.9 -0.8 -0.9 -1.1 0.2 -0.6 0.9 -0.4 0.5 0.5 1.1 -0.2 0.2 0.8 -0.3 0.6 0.0 0.1 -0.0 1.2 -0.1 0.6 0.6 0.0 -0.1
Allergy or Eczema 1.3 3.4 9.5 2.8 1.6 2.2 3.0 -0.1 3.1 -0.7 2.9 2.6 2.4 0.9 2.0 1.6 0.9 -2.8 1.6 1.1 -2.5 1.9 1.5 0.8 0.8 0.9 -1.3 1.1 1.0 0.6 1.4 1.7
Cardiovascular Disease 0.2 0.7 3.7 -1.5 -0.5 0.1 -0.1 -0.3 -0.9 -1.2 -0.1 -0.9 -1.0 0.1 -0.3 -0.6 -1.9 1.0 -0.7 0.6 0.6 -0.7 -1.1 -0.8 -1.0 -0.9 0.2 -0.8 -1.0 -0.7 -1.1 -0.9
Hypothyroidism (self reported) 2.7 6.1 17.9 -1.0 -3.7 -3.4 -2.5 2.5 -2.1 -3.9 -4.2 -1.2 -2.5 1.1 -3.2 -1.7 0.6 0.2 -2.6 -3.6 2.4 -3.3 -2.8 -1.9 -1.0 -1.1 -2.7 -1.7 -2.3 -1.9 -2.1 -2.5
Respiratory disease 1.1 2.4 9.9 2.9 0.4 1.3 3.1 0.3 3.1 0.2 2.1 1.7 1.7 -0.4 1.5 0.5 0.1 -2.6 1.0 0.1 -3.0 1.3 0.9 0.6 0.5 0.5 -1.5 0.6 0.9 0.1 1.0 1.2
Type 2 Diabetes (T2D) (2018) 0.7 1.2 3.0 -0.8 1.0 1.2 -0.4 -1.5 -0.7 0.2 0.6 0.9 0.8 1.6 0.7 1.3 1.0 0.9 0.9 1.7 0.3 1.4 -0.0 0.8 1.3 1.5 1.5 1.4 0.8 1.7 1.2 1.3
Lung FEV1/FVC ratio 4.7 24.1 77.9 -3.3 -7.3 -5.8 -5.0 5.2 -3.6 -4.4 -8.8 -3.6 -4.9 -0.0 -5.6 -4.9 0.0 1.5 -5.1 -8.1 4.8 -6.4 -6.4 -3.5 -2.6 -3.0 -4.6 -3.9 -5.0 -4.0 -4.3 -5.0
Lung FVC 0.6 2.9 13.0 2.8 -0.3 -0.7 0.4 0.8 -0.1 -2.2 1.8 -1.4 -0.2 -2.5 -0.9 -1.2 -3.2 -3.6 -1.1 -0.3 -2.7 0.3 -0.3 -2.4 -2.1 -1.8 -1.7 -1.6 -1.5 -1.5 -1.1 -0.7
Neuroticism 1.9 4.6 11.5 -1.3 1.1 1.4 2.2 -1.6 1.9 3.3 0.2 2.2 1.6 3.4 1.7 2.4 3.2 2.3 1.9 1.0 1.4 1.1 1.5 2.7 2.9 2.7 1.7 2.6 2.7 2.5 2.2 1.9
Chronotype (morning person) 0.4 0.8 4.5 0.9 1.1 -0.3 0.1 -0.4 -0.2 0.4 0.8 -1.3 0.1 -2.1 -0.3 -0.3 -1.8 -0.4 -0.4 1.0 -0.7 0.0 0.3 -1.1 -1.5 -1.5 0.6 -1.1 -0.4 -0.5 -0.9 -0.5
Hair Pigment 0.3 9.0 21.7 -1.3 -4.7 -3.8 -2.8 2.2 -2.8 -2.3 -3.9 -2.9 -3.8 -1.4 -3.7 -3.8 -1.2 0.4 -3.4 -3.7 0.4 -4.2 -3.0 -2.6 -2.7 -3.1 -2.0 -3.3 -1.9 -3.2 -3.3 -3.6
Tanning 0.1 0.6 3.7 -1.9 0.1 0.7 -0.6 1.9 0.7 -1.0 -0.1 0.6 0.2 0.5 -0.1 0.9 0.7 1.5 -0.2 0.8 1.4 0.1 -0.3 0.0 0.3 0.3 1.0 0.2 -0.4 0.2 0.2 0.1
Hand grip strength (left) 0.0 0.1 1.1 0.1 0.2 0.0 -0.1 -1.1 -0.5 0.5 -0.8 -0.3 -0.1 -0.0 -0.1 0.1 -0.2 0.1 -0.2 0.4 -0.2 0.0 0.2 -0.4 -0.3 -0.3 0.1 -0.2 -0.3 -0.0 -0.2 -0.1
Number of treatments/medications taken 0.6 1.1 6.6 -2.6 -0.1 0.5 0.2 -0.4 0.7 0.0 0.7 1.0 0.3 1.3 0.7 0.4 0.8 2.4 0.5 0.9 1.1 0.0 -0.1 1.2 1.0 0.8 1.6 0.8 1.2 1.5 0.6 0.5
Average weekly spirits intake 2.7 3.4 7.8 1.1 2.4 2.5 1.1 -2.4 0.8 1.1 1.7 2.2 2.2 0.6 2.2 2.0 1.1 -0.5 2.1 2.8 -1.5 2.6 1.8 1.3 1.2 1.5 1.8 1.7 2.1 2.1 1.8 2.1
Sensitivity / hurt feelings 0.5 0.8 4.8 -2.0 0.2 0.3 -0.8 0.5 -0.5 0.5 -0.9 0.6 0.0 0.5 -0.5 0.8 1.5 2.1 -0.3 0.8 1.8 0.1 0.2 -0.3 -0.1 -0.1 2.2 -0.0 0.5 0.8 -0.0 -0.1
Frequency of depressed mood in last 2 weeks 0.6 0.8 2.8 -1.2 -0.1 0.2 1.1 -0.5 1.1 1.1 0.3 1.0 0.9 1.7 0.6 0.8 1.3 1.2 0.6 0.4 1.1 0.3 -0.1 0.9 1.1 1.0 0.9 0.9 1.1 1.2 0.9 0.7
Hearing difficulty/problems: Yes 1.3 2.0 7.1 1.8 0.9 0.8 2.7 -0.1 2.2 1.8 1.9 1.3 1.4 -0.2 2.0 0.2 0.7 -1.7 1.7 -0.8 -2.1 1.2 1.3 1.5 1.1 1.1 -1.0 1.2 1.4 0.9 1.4 1.4
Relative age of first facial hair 0.1 0.2 1.6 0.3 0.2 0.0 -1.2 -0.1 -0.9 -0.1 -0.4 -0.5 0.1 -1.3 -0.0 -0.7 -0.3 -0.6 -0.0 -0.5 -0.8 0.3 -0.3 -0.2 -0.1 -0.2 0.4 -0.2 0.1 -0.0 0.1 0.1
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 1.6 -0.3 -0.2 -0.5 0.5 1.1 0.4 -1.3 0.6 -0.3 -0.3 -0.8 -0.3 -0.8 -0.5 -0.1 -0.4 -0.3 0.8 -0.3 -0.4 -0.7 -0.7 -0.6 0.0 -0.6 -0.1 -0.0 -0.6 -0.5
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.5 -0.9 0.4 -0.2 0.7 1.0 1.1 0.1 0.2 -0.1 0.1 -0.8 -0.0 0.2 0.0 0.9 -0.3 0.3 0.9 -0.3 0.2 0.0 -0.2 -0.4 1.2 -0.3 0.4 0.2 -0.3 -0.2
Ever had hysterectomy (womb removed) 0.5 0.6 2.2 -0.9 -0.3 -0.4 -1.1 1.2 -0.9 -0.7 -1.5 -0.7 -0.9 -0.2 -1.0 -0.3 -0.6 0.9 -0.9 0.1 1.1 -0.8 -0.1 -0.6 -0.7 -0.8 0.6 -0.8 -0.2 -0.3 -0.7 -0.8
Systolic blood pressure, automated reading 1.7 4.8 9.9 1.7 -1.2 -1.4 -2.7 0.5 -3.0 -2.4 -1.7 -2.7 -2.3 -2.3 -2.2 -2.2 -3.1 -2.2 -1.9 -1.1 0.1 -1.8 -1.0 -2.5 -2.7 -2.7 -2.4 -2.5 -2.4 -3.0 -2.4 -2.2
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 1.1 -0.4 -0.5 0.3 -1.0 0.2 -0.4 -0.8 -0.7 0.2 -0.1 0.2 -0.2 0.0 0.5 -0.1 -0.1 -0.1 0.1 0.1 -0.6 -0.0 0.1 0.2 -0.3 0.1 -0.3 0.1 0.1 0.1
Angina 0.5 0.7 2.3 0.6 0.9 0.6 -0.1 -0.8 0.4 1.0 -0.6 1.0 0.9 1.5 0.4 1.2 1.1 0.3 0.6 1.1 0.1 0.9 1.0 0.4 0.6 0.6 0.9 0.7 0.8 1.1 0.8 0.8
Medication for hormone replacement therapy 0.5 0.5 1.8 -0.6 -0.6 -0.2 -0.1 1.3 -0.0 -1.0 -0.9 -0.4 -0.7 -0.6 -0.8 -0.7 -0.8 0.2 -1.0 0.1 -0.1 -0.4 -0.5 -1.0 -1.0 -1.2 1.0 -1.1 0.1 -0.2 -0.7 -0.6
Vitamin and mineral supplements 1.1 1.5 4.4 0.3 -0.4 -1.1 0.4 -1.0 -1.0 -1.6 1.6 -1.7 -1.0 -1.8 -0.4 -1.3 -2.1 -1.0 -0.7 0.0 -1.4 -0.7 -1.1 -1.3 -1.6 -1.4 -1.5 -1.2 -1.4 -1.4 -1.4 -1.1
Supplements: Zinc 0.4 0.4 2.3 -0.2 -0.3 -0.5 0.3 0.3 0.5 0.7 -0.9 0.3 0.1 1.1 0.1 0.5 1.2 0.7 0.4 -0.2 1.5 -0.5 1.0 0.9 0.7 0.5 -0.0 0.5 1.0 0.3 0.3 0.0
Medication: Co-codamol 0.7 0.8 2.1 -1.2 -1.4 -1.5 -0.9 0.5 -1.1 -0.6 -0.4 -1.0 -1.1 0.5 -1.2 -0.4 0.0 0.7 -1.0 -0.9 1.2 -1.2 -1.0 -0.6 -0.5 -0.6 -0.1 -0.7 -0.5 -0.6 -0.8 -1.0
Medication: Metformin 0.2 0.3 2.3 -0.0 0.2 0.4 -0.3 -1.5 -0.6 -0.1 0.8 0.3 0.1 0.9 0.4 0.3 0.4 0.1 0.6 0.6 -0.5 0.3 -0.4 0.6 0.6 0.7 -0.2 0.7 0.4 0.7 0.4 0.4
Diabetes (father) 1.2 1.5 6.6 -2.2 -0.5 -0.4 -1.9 1.6 -1.8 -1.7 -0.3 -0.7 -1.3 -0.5 -1.5 -0.3 0.3 1.6 -1.2 -0.3 2.6 -1.2 -1.0 -0.9 -0.6 -0.6 0.8 -0.8 -1.0 -0.7 -1.0 -1.1
Diabetes (mother) 8.8 11.2 26.8 -2.3 2.4 2.4 0.5 -2.2 1.3 4.1 0.4 3.5 2.9 5.2 2.9 4.3 5.1 3.3 3.4 3.5 2.7 2.8 2.7 4.0 4.1 4.0 3.1 3.9 3.7 3.9 3.8 3.4
Severe depression (siblings) 1.1 1.2 3.7 -0.9 0.9 0.4 1.2 -0.1 1.2 1.2 0.6 1.6 1.2 1.5 1.0 1.2 1.9 0.6 0.9 -0.1 1.0 0.9 0.8 1.3 1.5 1.4 0.2 1.3 0.8 0.8 1.4 1.2
Pack years adult smoking proportion 1.3 2.0 4.0 -0.9 1.4 1.4 1.7 -1.0 1.2 1.9 2.0 1.5 1.6 0.8 1.5 1.5 1.0 0.7 1.2 1.8 -0.3 1.6 1.2 1.2 1.2 1.1 1.8 1.2 1.6 1.6 1.5 1.5
Impedance of leg (right) 3.5 16.8 32.5 -3.4 3.9 3.4 1.2 -1.3 1.7 3.2 0.7 4.0 3.3 5.2 3.2 5.6 4.0 5.3 3.4 5.5 4.4 3.5 3.9 4.7 5.1 4.9 5.7 4.8 4.3 4.6 4.5 4.1
Leg fat-free mass (left) 2.2 11.9 31.6 -0.2 -1.5 -2.7 -2.7 1.1 -3.9 -3.9 -0.6 -4.2 -3.2 -5.6 -3.2 -3.9 -4.1 -0.9 -3.4 -1.9 -1.1 -2.6 -3.4 -4.9 -5.3 -4.8 -0.8 -4.4 -4.1 -3.3 -4.5 -4.0
Trunk fat percentage 0.8 3.3 17.3 -3.9 0.1 -0.6 -4.2 0.8 -3.8 -1.1 -1.3 -1.1 -1.2 -1.4 -1.1 -0.3 0.2 4.1 -0.8 0.6 3.3 -0.8 -1.4 0.1 0.0 -0.1 2.7 -0.3 -0.3 0.4 -0.4 -0.7
Hand grip strength (right) 0.2 0.4 2.7 -0.1 -0.3 -0.1 -0.7 -0.8 -1.0 -0.2 -1.6 -0.9 -0.9 -0.7 -0.9 -0.6 -0.4 0.1 -0.8 0.0 0.3 -0.5 -0.1 -0.8 -0.7 -0.7 -0.0 -0.7 -0.6 -0.6 -0.6 -0.6
Townsend deprivation index at recruitment 1.4 2.0 4.9 0.7 0.7 1.1 1.1 -0.2 1.4 0.8 1.6 2.2 2.0 0.7 1.3 1.6 2.2 -0.7 1.4 0.8 -1.0 1.9 0.9 1.3 1.8 1.9 0.3 1.7 1.1 1.3 2.0 1.8
Current tobacco smoking 0.6 0.9 6.8 -2.0 1.2 0.9 -0.5 -0.4 -0.9 0.2 -0.7 0.2 0.2 -0.2 0.5 0.5 0.1 2.0 0.5 1.5 0.3 0.9 0.7 0.3 0.2 0.3 2.6 0.4 0.9 1.3 0.5 0.5
Average weekly fortified wine intake 0.3 0.3 2.4 1.6 0.1 0.2 0.3 -0.3 0.1 -0.0 -0.6 0.4 0.2 -0.1 -0.1 0.5 -0.4 -1.4 0.1 0.5 -1.0 0.3 0.6 -0.6 -0.6 -0.5 -0.5 -0.3 -0.1 -0.1 -0.1 0.1
Maternal smoking around birth 0.1 0.2 1.3 -0.6 0.4 0.5 0.1 -0.1 0.0 -0.9 0.4 -0.0 0.1 -0.8 0.1 -0.6 -0.3 0.6 0.1 0.6 -0.3 0.2 -0.4 -0.3 -0.4 -0.2 1.1 -0.1 0.1 0.5 -0.3 -0.1
Fed-up feelings 1.8 3.3 10.1 -0.9 1.3 1.6 0.7 -2.1 0.9 2.0 -0.7 2.2 1.9 2.2 1.9 2.0 3.2 1.2 2.0 1.7 1.1 1.7 1.0 2.0 2.2 2.2 1.2 2.2 1.7 2.3 2.0 1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 3.9 5.1 10.9 -1.9 1.7 1.8 1.3 -1.3 1.8 2.3 0.7 2.3 1.9 3.3 2.1 2.4 3.0 2.3 2.2 1.6 1.6 1.8 1.6 2.7 2.9 2.9 2.3 2.8 2.9 3.0 2.5 2.3
Relative age voice broke 1.2 1.8 5.2 0.5 -1.4 -0.8 -0.8 1.0 -0.7 -1.3 -0.5 -1.8 -1.3 -2.1 -1.1 -2.3 -1.5 -1.4 -1.1 -1.9 -1.1 -0.8 -1.4 -1.4 -1.4 -1.4 -1.5 -1.4 -1.2 -1.4 -1.1 -1.1
Taking other prescription medications 1.3 2.0 6.2 -1.0 0.4 0.3 1.9 -0.8 2.0 0.5 1.5 1.7 1.2 2.5 1.5 1.5 1.6 1.3 1.5 1.2 0.4 0.5 0.5 1.9 1.8 1.9 0.3 1.9 1.6 1.9 1.2 1.1
Age when periods started (menarche) 0.4 1.0 2.8 -0.4 -1.2 -1.7 0.3 0.6 -0.2 -0.7 -0.7 -1.4 -1.3 -0.7 -1.2 -1.3 -1.1 0.1 -1.2 -0.7 -0.1 -1.1 -0.9 -1.4 -1.3 -1.2 -0.3 -1.2 -0.9 -0.9 -1.3 -1.3
Bilateral oophorectomy (both ovaries removed) 3.1 3.6 9.3 -2.0 -1.7 -1.7 -3.0 2.9 -2.1 -1.5 -2.9 -1.8 -2.1 -1.4 -2.2 -1.8 -0.9 1.0 -2.1 -1.7 2.6 -2.0 -1.1 -1.5 -1.4 -1.8 -0.1 -2.0 -1.4 -1.9 -1.6 -1.9
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.7 6.8 0.8 -1.3 -0.5 1.2 1.5 1.8 -1.1 0.9 -0.7 -0.5 -1.2 -0.6 -2.6 -1.2 -1.3 -1.2 -2.6 -0.7 -1.2 -1.4 -1.1 -1.2 -1.3 -1.2 -1.4 -1.4 -1.5 -1.2 -1.2
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 3.2 -0.1 0.4 0.9 1.0 0.0 1.8 0.9 0.9 1.2 0.9 1.2 0.6 1.5 1.2 0.4 0.7 0.7 1.7 0.5 1.3 1.5 1.7 1.4 0.6 1.3 1.2 0.8 1.4 1.0
Qualifications: CSEs or equivalent 0.9 1.2 4.7 0.5 -1.5 -1.4 -0.9 1.1 -0.3 -1.3 -2.2 -0.3 -1.1 0.4 -1.1 -1.3 0.1 -1.1 -0.9 -2.0 0.4 -1.3 -0.9 -0.7 -0.5 -0.5 -2.0 -0.8 -1.0 -1.0 -0.8 -0.9
Serious illness, injury or assault to yourself 0.7 0.9 5.6 -0.7 1.4 1.2 0.7 -0.6 1.0 -0.0 2.4 0.4 0.6 -0.8 0.6 0.0 0.5 0.8 0.4 1.3 0.5 1.0 0.7 -0.2 -0.3 -0.2 2.2 0.1 1.0 1.3 0.2 0.4
High blood pressure 0.1 0.3 2.2 -0.8 -0.2 0.4 -0.0 -0.4 -0.4 -0.4 0.2 -0.6 -0.5 -0.4 -0.1 -0.3 -1.5 0.3 -0.4 1.1 0.1 -0.3 -0.3 -0.4 -0.7 -0.7 0.3 -0.5 -0.4 -0.4 -0.5 -0.4
Hayfever, allergic rhinitis or eczema 1.0 2.1 6.0 1.9 0.9 1.3 2.2 -0.2 2.4 -0.5 1.9 2.0 1.7 1.4 1.6 1.2 1.2 -2.2 1.5 0.5 -1.8 1.4 1.2 0.9 0.9 1.0 -1.3 1.1 1.1 0.6 1.2 1.4
Multivitamins +/- minerals 0.6 0.8 5.7 -0.6 0.1 0.1 -1.2 1.3 -0.2 0.9 -1.4 0.6 0.3 0.9 -0.3 0.8 1.4 1.2 0.1 -0.3 2.4 0.0 0.8 0.6 0.9 0.7 1.4 0.5 1.0 0.9 0.6 0.3
Stomach or abdominal pain in last month 0.5 0.6 5.6 -0.9 -0.2 0.6 -0.9 -0.2 -0.7 1.2 -1.2 0.1 -0.1 0.8 -0.5 0.5 1.2 1.7 -0.2 -0.0 2.4 -0.6 -0.1 0.4 0.4 0.2 0.5 0.1 0.2 -0.2 0.0 -0.2
Supplements: Glucosamine 0.4 0.6 3.1 0.2 1.2 1.1 -1.1 0.3 -1.0 -0.3 0.5 -0.2 0.0 -1.8 -0.0 -0.4 -1.0 0.1 -0.0 0.9 -0.6 0.6 0.9 -0.5 -0.7 -0.6 1.8 -0.4 0.3 0.3 -0.2 0.1
Diverticular disease/diverticulitis (self-reported) 1.4 1.6 4.2 0.6 0.5 1.4 1.6 -0.8 1.7 2.1 0.6 1.7 1.6 0.9 1.8 1.2 1.7 -0.3 1.7 0.6 -0.8 1.2 1.0 1.5 1.2 1.2 -0.6 1.3 1.2 0.8 1.3 1.4
Medication: Atenolol 3.0 3.8 8.4 -1.9 -1.4 -1.8 -1.8 0.6 -1.6 -1.8 -0.9 -2.7 -2.9 -1.5 -2.3 -2.2 -2.3 1.5 -2.2 0.2 1.4 -2.3 -1.4 -2.1 -2.6 -2.6 0.4 -2.4 -1.4 -1.5 -2.6 -2.5
Medication: Levothyroxine sodium 0.8 1.4 7.3 0.7 -1.4 -1.3 -1.5 1.5 -0.9 -1.4 -2.7 -0.1 -0.8 0.7 -1.2 -0.8 0.8 -1.0 -0.8 -2.5 1.2 -1.1 -0.6 -0.4 0.1 0.1 -2.1 -0.3 -0.8 -0.8 -0.3 -0.6
Sitting height 1.8 12.4 22.3 -1.4 -1.7 -3.8 -2.9 2.4 -4.3 -4.3 -1.4 -4.3 -3.7 -3.0 -4.2 -2.2 -4.3 0.5 -4.3 -0.6 2.9 -3.7 -2.0 -4.7 -4.7 -4.3 -0.0 -4.2 -4.3 -4.4 -4.7 -4.4
Chronic bronchitis/emphysema (father) 0.3 0.3 2.1 -0.7 -0.1 0.5 0.8 0.3 1.2 -0.3 1.5 0.7 0.7 -0.5 -0.1 -0.0 0.7 0.4 -0.4 0.2 -0.1 0.4 0.1 -0.5 -0.1 -0.2 1.4 -0.2 0.1 0.4 0.2 0.1
High blood pressure (mother) 0.5 0.7 2.2 -0.6 0.1 0.1 0.5 -0.4 0.5 1.1 0.4 0.7 0.5 1.4 1.0 0.4 0.7 1.0 0.9 0.0 0.8 0.4 0.7 1.5 1.3 1.1 0.6 1.1 1.3 1.2 1.0 0.8
Body mass index (BMI) 1.6 6.8 21.6 -0.5 -2.2 -2.1 -3.6 1.2 -3.5 -2.8 -1.3 -2.8 -2.4 -4.6 -2.2 -3.8 -2.2 -0.7 -2.3 -2.9 -0.7 -2.2 -3.3 -2.6 -2.9 -2.9 -1.7 -2.9 -2.8 -2.2 -2.7 -2.6
Impedance of leg (left) 3.1 15.0 34.6 -4.1 3.0 2.8 0.8 -0.9 1.3 3.0 -0.0 3.5 2.6 5.3 2.7 5.3 3.9 5.9 2.9 5.0 5.2 2.7 3.4 4.6 4.9 4.6 5.5 4.4 4.1 4.0 4.1 3.5
Leg predicted mass (left) 2.1 11.4 30.8 -0.3 -1.4 -2.6 -2.7 1.1 -3.9 -3.8 -0.6 -4.1 -3.1 -5.5 -3.2 -3.8 -4.0 -0.8 -3.3 -1.7 -1.0 -2.6 -3.3 -4.8 -5.1 -4.6 -0.7 -4.3 -4.0 -3.2 -4.4 -3.9
Trunk fat mass 1.2 5.3 23.1 -3.6 -0.3 -1.3 -4.6 1.0 -4.8 -2.2 -1.4 -2.4 -2.1 -3.1 -2.0 -1.5 -1.4 3.4 -1.8 0.2 2.7 -1.5 -2.2 -1.6 -1.8 -1.8 2.3 -1.7 -1.6 -0.7 -1.9 -2.0
Waist circumference 0.8 2.9 11.2 -2.2 0.0 -0.4 -2.6 -0.0 -3.1 -2.2 0.2 -1.7 -1.3 -3.4 -1.1 -1.5 -1.8 1.4 -1.3 0.7 -0.0 -0.5 -2.0 -2.0 -2.3 -2.1 1.6 -1.8 -1.5 -0.5 -1.8 -1.5
Number of incorrect matches in round 1.1 1.8 5.8 -1.8 0.4 1.1 0.9 -0.3 1.4 1.6 0.3 1.4 0.7 2.4 1.1 2.0 1.6 2.4 1.0 1.5 1.8 0.4 0.8 1.7 1.4 1.2 1.1 1.3 1.2 0.9 1.0 0.8
Past tobacco smoking 0.2 0.4 2.2 0.6 0.8 -0.1 -0.7 -1.0 -1.4 0.2 -0.4 -1.0 -0.1 -1.5 -0.2 -0.4 -0.9 -0.0 0.0 0.3 -0.1 0.3 -0.1 -0.4 -0.6 -0.4 0.6 -0.3 -0.4 -0.3 -0.3 -0.2
Alcohol usually taken with meals 1.6 2.6 6.5 0.0 -2.5 -1.7 -0.1 1.5 -0.6 -1.4 -1.2 -1.3 -1.6 0.6 -2.4 -0.2 -0.6 0.0 -2.2 -2.1 1.3 -2.4 -1.6 -1.7 -1.4 -1.7 -1.4 -1.9 -1.8 -2.2 -1.8 -2.0
Nervous feelings 1.4 2.6 11.4 0.3 0.6 0.9 1.3 -0.3 1.6 1.6 0.5 1.9 1.1 3.4 1.2 1.9 2.5 0.3 1.5 0.4 1.0 0.8 1.3 2.1 2.4 2.3 -0.4 2.2 1.9 1.4 1.8 1.7
Frequency of tenseness / restlessness in last 2 weeks 2.2 3.4 9.7 -2.5 0.8 1.1 1.2 -0.6 1.5 1.7 -0.6 1.8 1.3 2.9 1.0 1.8 2.8 3.1 1.1 0.6 2.7 0.6 0.7 1.9 2.4 2.3 2.5 2.1 1.9 2.4 1.7 1.4
Hearing difficulty/problems with background noise 0.5 0.8 9.7 0.6 -0.5 -0.0 3.1 0.1 2.1 0.8 1.8 0.5 0.5 0.4 0.6 0.0 0.1 -0.4 0.3 -0.4 -0.7 0.0 0.0 0.2 0.0 -0.1 -1.3 0.1 0.4 -0.2 0.1 0.2
Hair/balding pattern: Pattern 2 2.9 3.6 6.6 -0.6 -1.7 -2.3 -1.4 1.3 -1.9 -2.0 -1.4 -2.2 -2.3 -0.6 -2.3 -1.6 -2.0 0.5 -2.2 -1.3 1.3 -2.4 -2.0 -2.2 -2.3 -2.2 -0.6 -2.3 -2.1 -2.2 -2.6 -2.5
Had menopause 0.4 0.5 1.7 -0.6 0.4 0.3 0.8 -0.6 1.0 0.4 0.1 0.9 1.0 1.0 0.6 0.9 1.3 0.4 0.7 1.3 0.5 0.6 0.5 0.4 0.5 0.5 -0.1 0.6 0.4 0.5 0.6 0.6
Had other major operations 0.4 0.5 5.2 -0.5 -0.2 0.2 -0.8 1.0 0.1 -0.3 -2.3 0.8 0.1 1.1 -0.2 -0.0 1.1 0.6 0.1 -0.2 1.0 0.3 -0.3 0.1 0.5 0.4 0.4 0.2 0.2 0.7 0.5 0.4
Forced vital capacity (FVC) 0.5 1.9 8.3 1.4 0.9 -0.5 -0.6 -0.5 -1.7 -1.5 1.3 -1.9 -0.6 -2.6 -0.7 -0.2 -2.9 -1.5 -0.8 1.8 -0.9 -0.0 0.3 -1.8 -2.1 -1.7 0.2 -1.4 -1.1 -1.3 -1.5 -1.0
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.6 6.2 1.5 -0.6 -0.1 2.0 0.9 2.4 -0.6 1.2 -0.4 0.0 -1.1 -0.1 -2.5 -0.9 -1.6 -0.7 -2.4 -1.2 -0.7 -1.0 -1.0 -1.1 -1.1 -1.4 -1.1 -1.2 -1.3 -1.0 -0.9
Ever unenthusiastic/disinterested for a whole week 0.6 0.8 5.2 -1.6 -0.4 -0.2 0.1 0.3 0.2 0.4 0.5 0.9 0.3 0.5 0.1 0.5 1.8 1.9 0.2 -0.0 2.3 -0.2 0.4 0.8 0.9 0.7 1.0 0.5 1.1 0.9 0.5 0.3
Qualifications: None of the above 3.1 6.6 11.6 -1.0 2.2 2.7 1.1 -1.9 2.2 2.9 1.1 3.0 2.5 2.2 2.8 3.1 2.9 1.7 2.7 2.9 0.4 2.5 2.0 3.4 3.3 3.1 2.1 3.1 3.0 3.0 3.2 3.0
Financial difficulties in last 2 years 0.2 0.3 2.8 -1.7 -0.0 -0.3 1.0 -0.0 0.2 0.3 -0.2 0.3 0.4 -0.3 0.4 0.2 -0.1 1.4 0.0 0.7 0.2 0.3 -0.3 0.1 -0.0 -0.0 1.2 0.1 -0.1 0.5 0.1 0.1
Mouth/teeth dental problems 1.3 2.0 5.4 -0.8 -0.9 -1.2 -1.5 0.3 -1.5 -2.3 -0.6 -1.4 -1.2 -1.7 -1.6 -1.3 -1.5 0.4 -1.7 -0.1 0.6 -1.1 -1.9 -2.1 -2.0 -1.8 0.2 -1.8 -1.8 -1.1 -1.8 -1.6
Heart attack 2.0 2.6 6.7 -1.2 0.8 0.9 2.2 -1.8 2.1 2.0 0.3 1.6 1.5 2.6 1.3 1.7 2.4 1.9 1.4 1.3 1.1 0.9 1.1 1.8 1.9 1.9 1.2 1.8 1.6 1.8 1.5 1.4
Allergy 0.9 2.2 9.1 -2.0 -0.5 -1.3 -2.7 -0.3 -3.0 0.5 -1.5 -2.1 -1.6 -1.6 -1.5 -1.4 -1.1 2.0 -1.3 -0.6 1.6 -1.1 -1.1 -1.0 -1.1 -1.1 1.5 -1.1 -1.1 -0.4 -1.2 -1.3
Pain all over the body in last month 1.5 1.6 3.2 -0.5 1.0 0.5 1.2 -1.1 1.7 1.7 -0.1 1.2 1.4 1.5 1.3 1.4 1.2 0.8 1.3 1.1 0.1 1.1 1.2 1.5 1.5 1.4 1.0 1.5 1.4 1.8 1.4 1.4
Diabetes (self-reported) 0.3 0.4 3.1 -0.8 0.7 0.5 -0.1 -1.2 -0.6 -0.3 0.1 0.2 0.0 1.0 0.1 0.8 0.3 0.7 0.4 1.8 0.9 0.5 -0.0 0.2 0.4 0.7 0.9 0.6 0.1 0.7 0.4 0.4
Hayfever/allergic rhinitis (self-reported) 6.5 8.5 15.8 0.2 3.3 3.3 2.2 -1.9 2.3 3.0 3.2 4.0 3.3 2.9 3.4 3.4 2.7 0.9 3.2 3.1 -0.3 3.2 2.9 3.2 3.2 3.2 2.1 3.3 3.2 3.1 3.4 3.4
Medication: Ramipril 0.5 0.7 1.8 -0.7 0.8 0.4 -0.1 -0.7 -0.1 0.6 -0.1 0.5 0.4 1.4 0.6 1.1 1.2 0.9 0.9 0.9 0.6 0.7 1.0 0.8 0.7 0.6 1.2 0.7 1.2 1.2 0.7 0.7
Medication: Simvastatin 0.7 1.0 6.6 -2.6 -0.1 -0.0 -0.4 0.6 -0.2 -1.0 0.8 0.4 -0.4 1.7 -0.5 0.5 0.6 2.3 -0.6 1.1 2.3 -0.4 -0.3 -0.3 0.0 -0.0 1.8 -0.1 0.1 0.6 -0.2 -0.4
Fluid intelligence score 0.8 1.6 10.6 2.1 0.8 0.7 0.6 -0.2 0.0 -0.2 1.5 -0.5 0.7 -3.2 0.0 -1.3 -1.3 -2.6 -0.2 -0.3 -2.6 1.1 0.6 -1.7 -1.7 -1.4 0.0 -1.1 -0.5 -0.5 -0.5 0.0
Illnesses of siblings 0.8 1.2 6.7 0.8 -0.9 -1.2 -1.3 0.5 -1.5 -0.6 -2.6 -1.3 -1.3 -0.4 -1.3 0.1 -0.3 -0.2 -0.8 -0.8 -0.2 -1.3 -0.2 -1.0 -1.2 -1.2 -1.0 -1.1 -0.8 -1.0 -1.3 -1.2
Neuroticism score 3.6 7.4 17.6 -0.9 1.9 2.5 2.3 -1.8 2.3 3.7 0.7 3.2 2.5 3.6 2.4 3.1 4.2 2.0 2.7 1.7 1.5 2.1 2.4 3.2 3.4 3.3 2.3 3.2 3.4 3.4 3.0 2.8
Weight 2.0 9.7 30.0 -1.9 -1.1 -2.2 -4.2 1.1 -4.9 -3.5 -1.2 -3.8 -3.0 -5.5 -2.9 -3.3 -3.3 0.9 -2.9 -1.0 0.6 -2.3 -3.2 -3.8 -4.2 -3.9 0.4 -3.7 -3.4 -2.5 -3.8 -3.4
Impedance of arm (right) 2.7 12.6 28.0 -3.3 2.6 2.7 0.4 -0.2 1.4 2.8 -0.3 3.3 2.1 5.3 1.9 5.0 3.9 5.1 2.4 4.3 4.2 2.2 3.2 4.3 4.8 4.4 5.1 4.0 4.1 3.8 3.9 3.3
Arm fat percentage (right) 1.0 3.9 18.1 -2.1 -1.5 -1.4 -4.2 1.6 -3.8 -2.1 -1.6 -1.9 -1.9 -3.1 -1.9 -2.3 -1.0 1.4 -1.7 -1.6 1.0 -1.6 -2.7 -1.2 -1.4 -1.5 0.0 -1.7 -1.7 -1.1 -1.5 -1.7
Trunk fat-free mass 2.8 16.3 41.5 -0.4 -1.5 -3.1 -2.8 1.1 -4.3 -4.4 -0.7 -5.0 -3.8 -6.3 -3.7 -4.3 -5.3 -1.1 -4.0 -1.4 -0.9 -3.1 -3.3 -5.9 -6.4 -5.8 -1.0 -5.3 -5.0 -4.1 -5.5 -4.7
Hip circumference 1.1 4.6 14.0 -1.0 -1.1 -1.6 -3.5 0.4 -3.7 -2.6 -0.9 -2.5 -2.0 -3.5 -1.9 -2.5 -1.8 0.1 -1.9 -1.1 -0.2 -1.6 -2.6 -2.4 -2.7 -2.5 -0.4 -2.4 -2.3 -1.5 -2.5 -2.3
Time employed in main current job 0.2 0.3 1.6 1.2 -0.3 -0.0 -1.1 -1.2 -0.5 0.5 -0.9 0.3 0.2 0.3 -0.3 -0.0 1.3 -0.1 0.1 -0.1 -0.3 -0.3 0.0 -0.0 -0.1 0.0 -0.2 0.0 0.1 0.0 -0.2 -0.2
Alcohol intake versus 10 years previously 0.5 0.8 7.0 -1.1 0.6 0.3 -1.1 0.2 -0.6 -0.3 1.1 -0.4 0.3 -1.8 -0.4 -0.7 -0.3 1.3 -0.4 0.5 0.0 0.4 -0.4 -1.0 -0.9 -0.9 2.6 -0.8 0.0 0.6 -0.4 -0.2
Father’s age at death 1.8 2.4 11.0 -0.3 -1.3 -1.4 -3.3 0.8 -2.6 -1.4 -2.1 -1.9 -2.1 -1.0 -2.0 -1.1 -0.6 0.2 -1.4 -1.1 0.7 -2.1 -0.6 -1.1 -1.4 -1.5 -0.8 -1.4 -1.2 -1.5 -1.8 -1.7
Worrier / anxious feelings 1.3 2.5 6.6 -0.5 1.2 1.3 1.9 -0.8 1.7 2.6 1.0 1.8 1.5 2.1 1.5 1.7 2.0 1.1 1.5 0.9 1.0 1.2 1.3 1.9 2.0 1.9 1.1 1.8 1.9 1.8 1.7 1.6
Frequency of tiredness / lethargy in last 2 weeks 3.6 5.9 12.0 -0.9 2.0 2.3 2.9 -1.3 3.3 1.9 2.1 2.9 2.9 2.6 2.7 2.1 2.9 1.2 2.4 1.8 -0.3 2.4 1.5 2.5 2.8 2.8 2.3 2.8 2.9 3.5 2.8 2.7
Falls in the last year 1.1 1.6 5.5 1.0 1.9 2.3 2.0 -0.2 1.2 0.8 2.1 1.5 1.6 -0.9 1.5 1.2 0.1 -0.5 1.2 1.0 -1.4 1.6 1.0 0.6 0.4 0.5 1.1 0.8 1.1 0.8 0.9 1.2
Hair/balding pattern: Pattern 3 1.2 1.8 11.2 3.2 -0.3 -0.7 0.5 -0.3 -0.2 0.2 0.2 -1.2 -0.5 -1.9 -0.2 -1.0 -1.5 -3.3 -0.1 -1.5 -2.3 -0.7 0.4 -0.5 -1.0 -1.0 -2.7 -0.9 -0.5 -1.3 -0.9 -0.6
Number of live births 0.4 0.5 4.5 -1.1 0.5 -0.2 -0.4 0.5 -0.5 0.8 -2.1 0.6 0.2 0.4 0.0 0.6 1.2 1.2 0.2 -0.1 1.4 0.0 0.4 0.5 0.6 0.4 0.9 0.3 0.4 0.3 0.4 0.2
Forced expiratory volume in 1-second (FEV1) 1.3 4.3 8.1 0.3 -1.1 -2.2 -2.2 1.1 -2.8 -2.6 -1.7 -2.7 -2.0 -2.6 -2.3 -1.7 -2.6 -0.7 -2.2 -0.8 0.8 -1.8 -1.5 -2.7 -2.6 -2.4 -1.1 -2.3 -2.6 -2.3 -2.5 -2.3
Pulse rate 0.2 0.4 2.1 -1.1 0.0 0.1 -1.1 -0.3 -0.8 -0.3 -0.3 -0.1 0.1 -0.4 -0.3 0.5 1.0 1.4 -0.1 1.0 1.1 -0.1 -0.1 0.0 0.1 0.1 1.1 0.0 -0.2 -0.1 -0.0 -0.1
Happiness 0.2 0.2 1.0 -0.8 0.2 0.2 0.3 -0.9 -0.4 1.0 0.0 -0.2 0.2 -0.2 0.2 0.4 -0.3 0.7 -0.0 0.9 0.0 0.2 -0.5 0.0 -0.0 0.1 0.9 0.2 0.1 0.3 -0.0 0.1
Noisy workplace 2.1 2.6 7.1 -0.4 1.2 1.9 0.8 -0.0 1.9 2.7 1.5 1.5 1.4 1.2 1.4 1.1 1.4 1.1 1.4 0.6 0.3 1.3 1.5 2.2 2.1 1.8 2.1 1.7 2.4 2.4 2.0 1.8
Qualifications: A levels/AS levels or equivalent 0.6 1.4 4.6 0.8 -0.1 -0.3 -0.1 0.8 -1.3 -1.5 0.4 -1.3 -0.9 -1.7 -0.9 -0.5 -1.9 -1.1 -0.9 -0.1 -0.6 -0.8 0.1 -1.9 -2.1 -1.9 -0.4 -1.6 -0.7 -1.2 -1.7 -1.2
Serious illness, injury or assault of a close relative in last 2 years 2.4 2.8 8.4 0.2 2.2 2.0 2.3 -1.2 1.8 0.6 2.9 1.9 2.4 0.5 2.0 1.6 0.8 -0.1 1.7 2.1 -0.7 2.5 1.2 1.1 1.3 1.6 1.6 1.6 1.2 1.8 1.8 1.9
Mouth/teeth dental problems: Dentures 3.5 5.9 10.8 0.2 2.2 2.8 1.1 -1.8 1.6 3.0 0.7 2.8 2.2 2.5 2.6 3.0 2.7 0.6 2.8 2.6 -0.1 2.2 2.8 3.3 3.1 2.9 1.1 2.9 3.2 2.6 3.0 2.8
Asthma 1.2 2.4 12.3 3.0 -0.1 0.9 3.0 -0.0 3.3 0.3 1.5 1.3 1.5 -0.3 1.4 0.0 0.1 -3.2 1.1 -0.0 -3.5 1.1 0.7 0.4 0.2 0.3 -1.8 0.5 0.8 0.0 0.7 0.9
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 2.2 -0.7 0.3 0.9 1.1 -1.0 1.3 1.1 0.5 1.4 1.3 1.0 0.6 1.1 1.2 1.3 0.5 0.9 0.5 0.7 0.5 0.7 0.9 0.8 1.5 0.8 1.0 1.2 0.9 0.8
Medication: Cholesterol lowering 0.6 1.0 5.7 -1.0 -0.0 0.4 0.2 -1.1 0.0 0.5 0.8 0.9 0.3 2.4 0.3 1.1 1.6 1.6 0.5 1.3 1.2 0.1 0.7 0.9 1.1 1.0 1.1 0.9 1.2 1.1 0.7 0.5
Depression (self-reported) 1.5 1.8 4.9 -0.8 1.6 1.2 1.8 -0.6 2.2 0.7 1.6 1.2 1.2 0.6 1.5 0.7 1.4 0.8 1.4 1.1 0.7 1.2 2.0 1.6 1.5 1.5 0.7 1.6 1.4 1.2 1.4 1.4
Medication: Lansoprazole 0.2 0.3 1.5 -1.2 -0.6 -0.4 0.2 0.6 0.1 -0.6 0.1 -0.3 -0.8 0.7 -0.5 -0.3 -0.6 0.5 -0.5 0.2 0.7 -0.6 -0.4 -0.3 -0.3 -0.3 -0.1 -0.3 -0.5 -0.1 -0.5 -0.5
Prospective memory result 0.6 0.7 3.8 -1.7 -0.9 -1.2 0.1 0.5 0.0 0.4 -1.7 -0.6 -0.8 0.5 -0.5 -0.6 0.4 1.8 -0.6 -0.8 1.9 -1.1 -0.9 0.2 0.1 -0.2 0.4 -0.3 -0.3 0.1 -0.4 -0.7
Lung cancer (father) 0.4 0.5 3.5 -0.1 -0.6 -0.4 -1.3 -0.3 -0.9 -0.2 -1.9 -0.7 -0.7 0.0 -0.8 -1.0 -0.0 0.3 -0.6 -0.7 1.0 -0.5 -0.8 -0.5 -0.3 -0.3 -0.4 -0.4 -0.5 -0.1 -0.4 -0.5
Illnesses of mother 1.4 1.8 5.6 1.6 -0.8 -0.7 0.0 0.9 0.0 -1.2 -0.5 -1.0 -0.9 -2.2 -0.9 -1.2 -1.3 -2.4 -1.1 -2.0 -1.4 -0.8 -0.7 -1.4 -1.4 -1.3 -2.3 -1.4 -1.5 -2.0 -1.1 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.2 3.8 8.6 0.9 -1.3 -1.8 -2.5 0.9 -2.9 -2.1 -1.8 -2.3 -1.6 -2.7 -2.2 -1.8 -2.2 -1.2 -2.1 -1.1 0.2 -1.5 -1.5 -2.6 -2.4 -2.2 -1.3 -2.2 -2.3 -2.1 -2.2 -2.0
Pulse wave Arterial Stiffness index 1.7 2.0 8.6 -2.9 -1.5 -2.6 -0.8 0.5 -0.7 -1.4 -2.1 -1.1 -1.3 0.9 -1.6 -0.1 0.5 2.3 -1.5 0.3 2.1 -1.4 -1.5 -1.3 -0.9 -0.9 0.4 -1.0 -1.2 -0.3 -1.2 -1.5
Impedance of arm (left) 2.8 12.9 26.6 -2.8 2.9 2.8 0.4 -0.7 1.2 2.9 -0.0 3.3 2.4 5.0 2.1 5.0 4.0 4.8 2.6 4.3 4.1 2.5 3.4 4.4 4.9 4.5 5.2 4.2 4.3 4.0 4.1 3.5
Arm fat mass (right) 2.0 8.1 22.3 -2.3 -1.7 -2.2 -4.5 1.6 -4.7 -3.1 -1.5 -3.2 -2.9 -4.6 -2.7 -3.3 -2.5 1.4 -2.7 -1.6 1.0 -2.5 -3.3 -2.8 -3.1 -3.1 0.1 -3.1 -2.9 -2.1 -3.1 -3.0
Trunk predicted mass 2.8 16.0 41.0 -0.4 -1.5 -3.1 -2.8 1.0 -4.3 -4.4 -0.6 -4.9 -3.7 -6.2 -3.6 -4.3 -5.3 -1.1 -4.0 -1.3 -1.0 -3.0 -3.3 -5.8 -6.4 -5.8 -1.0 -5.2 -4.9 -4.1 -5.5 -4.6
Standing height 0.7 7.2 21.9 -3.6 1.8 -0.8 -2.4 0.3 -4.1 -2.4 -0.2 -3.0 -2.1 -2.6 -2.1 0.4 -3.1 3.7 -2.2 3.8 3.2 -1.0 -0.3 -3.3 -3.6 -3.0 4.7 -2.5 -2.1 -1.2 -3.1 -2.5
Length of working week for main job 0.4 0.4 1.6 -1.1 -0.1 0.5 -1.0 -0.0 -0.5 0.2 -0.6 0.7 0.5 -0.4 0.4 0.2 1.3 0.8 0.3 0.2 -0.3 0.8 -0.6 0.4 0.8 0.7 0.3 0.6 0.2 0.9 0.9 0.7
Exposure to tobacco smoke at home 1.6 1.8 5.2 0.9 1.0 1.2 1.6 -0.9 1.8 2.3 1.2 2.0 1.8 1.0 1.6 0.8 1.7 -0.4 1.5 0.1 -0.4 1.2 1.2 1.5 1.6 1.5 -0.6 1.5 1.1 1.1 1.6 1.5
Breastfed as a baby 0.4 0.4 2.1 1.4 -0.5 -0.7 -0.0 0.4 0.1 -0.6 -1.0 -0.5 -0.5 0.1 -0.5 -0.6 -0.9 -1.4 -0.4 -0.8 -0.6 -0.3 -0.0 -0.6 -0.5 -0.4 -1.1 -0.5 -0.6 -0.6 -0.4 -0.4
Tense / ‘highly strung’ 1.6 2.7 7.9 -1.9 1.0 1.2 2.0 -0.6 1.5 1.1 0.6 1.8 1.1 2.8 1.4 2.0 2.1 2.5 1.3 1.4 1.2 0.6 0.7 1.9 1.9 1.9 1.8 1.8 2.0 1.9 1.2 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.7 3.2 -1.8 -0.1 -0.0 1.0 0.8 1.0 0.3 0.5 0.9 0.3 1.1 0.2 1.0 1.2 1.5 0.1 0.3 1.3 0.0 0.4 0.7 1.0 0.8 0.7 0.7 0.8 0.7 0.6 0.5
Hair/balding pattern: Pattern 4 1.1 2.7 12.4 -3.5 0.9 -0.0 -0.1 0.1 -1.0 -1.8 2.6 -1.3 -1.4 -1.7 -0.4 -0.5 -2.6 2.4 -1.0 3.4 0.5 0.2 -0.7 -1.6 -2.0 -1.7 2.4 -1.2 -1.1 -0.4 -1.3 -1.0
Birth weight of first child 1.1 2.0 3.9 1.4 1.3 1.2 0.4 -1.3 0.5 1.2 0.3 1.6 1.4 1.9 1.4 1.9 1.7 -0.5 1.7 0.5 -1.2 1.6 0.9 1.5 1.7 2.0 0.2 1.9 1.2 1.8 1.7 1.6
Peak expiratory flow (PEF) 2.9 6.6 11.6 0.3 -1.8 -2.5 -3.0 1.9 -3.2 -3.0 -3.1 -2.8 -2.6 -2.3 -2.9 -2.5 -3.0 -1.0 -2.8 -1.9 0.9 -2.4 -2.4 -3.2 -2.9 -2.6 -2.1 -2.8 -3.4 -2.9 -3.0 -2.7
Pulse wave reflection index 0.9 1.1 4.8 -0.9 -1.6 -2.2 0.3 0.5 0.5 -1.0 -0.8 -1.0 -1.1 0.1 -1.1 -1.2 -0.7 0.1 -1.3 -0.9 0.2 -1.1 -1.1 -1.4 -1.2 -1.3 -0.8 -1.3 -0.9 -0.5 -1.1 -1.2
Ever highly irritable/argumentative for 2 days 4.0 4.8 16.0 -3.9 1.3 1.8 0.8 -0.0 1.6 1.8 1.6 2.1 1.4 1.1 1.2 2.5 3.4 4.0 1.2 2.9 2.3 1.4 1.3 1.9 2.1 1.8 3.8 1.8 2.3 2.8 1.9 1.7
Loud music exposure frequency 0.2 0.2 2.1 0.0 -0.1 -0.5 0.2 0.0 0.3 -0.1 0.7 -0.6 0.1 -1.5 -0.1 -0.4 -0.2 -0.1 -0.2 -0.5 0.5 -0.1 -0.5 -0.1 -0.1 -0.1 -0.4 -0.2 -0.6 -0.3 -0.1 -0.2
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 2.2 0.4 -0.5 -0.7 0.2 1.2 -0.5 -1.5 0.2 -0.7 -0.6 -0.6 -0.8 -0.5 -0.7 -0.7 -0.9 -1.1 0.3 -0.7 -0.7 -1.3 -1.1 -1.0 -0.5 -1.0 -1.0 -1.0 -1.0 -0.9
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 2.4 -1.4 -0.7 -1.0 -0.7 0.9 -0.8 0.2 -1.5 -1.5 -1.5 -0.3 -1.0 -1.0 -0.6 1.4 -0.8 -1.0 1.5 -1.4 -0.1 -0.0 -0.3 -0.5 0.6 -0.6 -0.3 -0.8 -0.8 -1.0
Blood clot in the leg (DVT) 1.1 1.5 14.1 -2.0 -0.3 -0.6 -1.3 1.0 -1.3 0.3 -1.6 -0.1 -0.8 1.7 -1.1 1.2 0.6 2.6 -0.8 -0.0 3.8 -0.9 0.2 0.1 0.4 0.2 1.2 -0.0 -0.2 -0.3 -0.1 -0.5
Medication: Paracetamol 0.9 1.5 8.0 -1.8 1.1 0.9 -0.8 -0.7 -0.7 1.2 0.9 0.7 0.3 1.3 0.6 1.2 0.8 2.0 0.7 1.6 0.8 1.1 1.0 1.0 1.0 0.8 2.8 0.9 1.5 1.8 1.1 1.0
Headache pain in last month 0.5 0.8 2.5 -0.6 -0.6 -0.9 -1.6 1.2 -1.5 0.3 -1.3 -1.1 -0.8 -1.2 -0.9 -0.8 -0.7 1.4 -0.6 -1.2 0.7 -0.8 -0.1 -0.1 -0.2 -0.5 1.4 -0.5 0.4 0.1 -0.4 -0.6
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 2.0 -0.3 -0.0 -0.3 -0.6 1.4 0.3 -0.1 -0.9 -0.0 -0.1 -0.8 -0.4 -0.2 0.4 0.1 -0.4 -1.0 0.6 0.1 0.0 -0.2 0.0 -0.1 0.6 -0.2 -0.1 -0.1 0.2 -0.0
Glaucoma (self-reported) 0.3 0.3 1.0 -0.5 -0.4 -0.3 -0.6 -0.5 -0.9 -1.0 0.5 -0.2 -0.4 -0.1 -0.2 0.7 -0.7 0.6 -0.3 0.9 0.5 -0.4 -0.9 -0.6 -0.7 -0.5 -0.2 -0.4 -0.5 -0.2 -0.7 -0.6
Gout (self-reported) 3.8 5.3 10.5 0.9 2.2 2.5 1.7 -1.4 1.9 1.9 0.8 2.9 2.3 2.7 2.8 2.7 2.5 -0.2 2.8 1.2 -0.4 2.3 2.1 3.1 3.2 3.2 0.2 3.1 2.2 2.4 2.9 2.8
Hypothyroidism/myxoedema (self-reported) 1.9 3.7 15.0 -0.7 -2.7 -2.4 -2.5 2.2 -2.0 -2.9 -3.9 -0.8 -2.0 0.9 -2.4 -1.0 0.4 0.3 -1.8 -2.8 2.2 -2.5 -1.7 -1.2 -0.6 -0.7 -2.0 -1.1 -1.3 -1.3 -1.5 -1.8
Medication: Amlodipine 0.5 0.7 5.4 1.5 -0.5 0.6 0.7 0.0 0.9 -0.4 0.5 0.4 0.5 -0.1 0.4 -0.7 0.1 -1.9 0.4 -1.0 -2.3 0.5 -0.8 -0.3 -0.0 0.2 -1.9 0.2 -0.4 -0.0 0.2 0.4
Medication: Ventolin 100micrograms inhaler 1.0 1.3 6.2 2.3 -0.0 0.4 2.5 0.2 2.4 -0.3 1.0 1.1 1.0 -0.1 0.7 0.6 0.3 -2.4 0.7 -0.1 -1.9 0.5 0.5 0.1 0.1 0.3 -2.2 0.4 -0.0 -0.4 0.3 0.5
Birth weight 4.1 8.9 15.5 2.6 3.6 3.9 2.4 -3.9 2.5 3.4 2.9 2.9 3.6 1.1 3.8 2.7 1.4 -1.0 3.7 3.0 -3.8 3.7 2.9 2.5 1.9 2.3 2.0 2.8 3.3 3.3 2.7 3.3
Chronic bronchitis/emphysema (mother) 3.0 3.4 8.0 0.7 0.5 1.3 2.0 -1.2 2.6 2.8 1.6 2.6 2.8 0.8 2.4 0.7 2.5 -0.6 2.1 -0.5 -2.1 1.8 0.5 2.1 2.2 2.2 -0.3 2.1 1.5 1.8 2.3 2.1
High blood pressure (siblings) 0.4 0.6 1.9 -0.7 -0.4 -0.1 -0.8 1.3 -0.7 -1.2 1.0 -0.4 -0.4 -1.2 -0.6 -1.2 -0.9 -0.3 -0.8 -0.8 0.3 -0.3 -1.4 -0.8 -0.7 -0.6 -0.2 -0.7 -1.1 -0.8 -0.6 -0.5
Forced vital capacity (FVC), Best measure 0.5 1.8 7.2 1.6 0.3 -0.6 -1.1 -0.1 -1.8 -1.3 0.7 -1.7 -0.6 -2.7 -1.0 -0.5 -2.4 -1.8 -1.0 1.2 -0.9 -0.1 0.2 -2.0 -2.0 -1.7 -0.3 -1.4 -1.2 -1.3 -1.3 -0.9
Body fat percentage 0.7 2.8 16.7 -3.4 -0.1 -0.6 -4.1 0.7 -3.8 -1.1 -1.3 -1.1 -1.1 -1.7 -1.0 -0.7 -0.0 3.4 -0.8 0.2 2.7 -0.8 -1.5 0.0 -0.1 -0.3 2.0 -0.4 -0.5 0.2 -0.5 -0.8
Leg fat percentage (right) 0.5 1.7 13.5 -2.3 0.2 -0.1 -3.7 0.0 -3.3 -0.9 -0.9 -0.8 -0.6 -2.0 -0.3 -0.7 0.1 2.3 -0.1 0.3 1.5 -0.2 -1.3 0.2 -0.1 -0.1 1.3 -0.1 -0.4 0.5 -0.2 -0.3
Arm fat-free mass (right) 2.6 13.1 34.1 -0.7 -1.4 -3.1 -2.9 1.0 -4.3 -4.1 -0.8 -4.5 -3.3 -5.8 -3.2 -4.0 -4.5 -0.6 -3.5 -1.6 -0.4 -2.7 -3.3 -5.1 -5.6 -5.0 -1.0 -4.6 -4.5 -3.6 -4.8 -4.2
Exposure to tobacco smoke outside home 1.1 1.5 4.1 -0.1 0.6 1.1 1.1 -1.8 0.5 2.0 1.3 1.3 1.0 1.3 1.3 1.4 1.5 1.0 1.3 0.8 0.2 0.6 1.1 1.7 1.5 1.4 0.7 1.4 1.7 1.3 1.1 1.1
Comparative body size at age 10 4.8 13.1 22.6 -3.1 -3.2 -2.6 -2.9 2.1 -3.7 -3.6 -2.3 -4.0 -3.7 -3.9 -3.9 -4.3 -3.0 2.0 -4.1 -3.1 1.7 -3.7 -4.6 -4.5 -4.8 -4.7 -0.2 -4.6 -4.2 -3.0 -4.6 -4.4
Number of full brothers 1.3 1.6 8.1 1.4 1.1 0.8 2.8 -2.0 1.7 1.4 1.6 0.6 0.7 0.5 1.7 0.2 -0.5 -1.8 1.3 1.3 -2.3 1.2 0.9 0.9 0.5 0.6 -1.0 0.8 0.6 0.6 0.8 1.1
Worry too long after embarrassment 2.4 4.0 8.2 -0.4 1.7 1.4 0.8 0.3 1.6 2.6 0.4 2.4 1.8 2.9 1.6 2.5 2.6 1.5 1.9 1.2 1.3 1.5 2.8 2.4 2.5 2.3 2.3 2.3 2.8 2.1 2.2 2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 5.1 -0.5 0.9 0.5 2.3 0.0 2.1 1.0 1.9 1.1 1.2 0.6 1.0 0.7 1.2 0.7 0.7 0.2 0.9 0.7 0.8 0.9 1.0 0.9 0.7 0.9 0.9 0.9 0.9 0.8
Wheeze or whistling in the chest in last year 3.9 6.9 21.2 1.0 2.0 2.6 4.6 -1.8 4.2 1.9 2.8 3.6 3.3 1.8 3.3 2.4 2.4 -0.8 2.9 2.3 -1.7 2.9 2.1 2.4 2.5 2.6 0.1 2.8 2.3 2.4 2.8 3.0
Number of children fathered 0.2 0.2 1.2 0.7 0.3 0.5 0.7 0.0 0.5 -0.1 0.7 0.4 0.5 0.1 0.3 0.1 -0.4 -1.1 0.1 0.4 -0.6 0.3 0.3 -0.2 -0.1 -0.1 -0.8 -0.1 -0.5 -0.5 0.1 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.0 0.6 -0.8 -0.5 0.5 -0.4 0.5 -0.8 0.6 -0.5 -0.2 -0.8 -0.2 -1.0 -0.5 -1.0 -0.5 -0.6 -0.9 -0.4 -0.8 -0.8 -0.9 -0.8 -1.0 -0.8 -1.0 -0.9 -0.6 -0.6
Age at first live birth 2.9 5.2 12.0 1.4 -2.0 -1.7 -0.7 1.6 -1.7 -2.7 -0.4 -2.7 -2.1 -1.9 -2.4 -2.2 -3.5 -1.7 -2.5 -1.8 -0.6 -2.2 -1.5 -3.1 -3.1 -2.9 -1.8 -2.8 -2.6 -3.0 -2.9 -2.6
Pulse wave peak to peak time 1.4 1.6 6.6 2.5 1.6 2.6 0.8 -0.4 0.5 1.1 2.2 0.8 1.1 -1.1 1.4 0.1 -0.7 -1.9 1.3 0.0 -2.0 1.4 1.3 1.0 0.6 0.7 -0.0 0.8 1.1 0.3 1.0 1.2
Health satisfaction 0.9 1.1 3.0 -1.2 1.1 1.1 -0.3 0.1 0.5 0.9 -0.1 1.6 1.6 0.1 1.0 0.6 1.7 0.9 0.8 0.9 0.6 1.5 0.5 0.6 1.1 1.2 1.7 1.2 0.8 1.5 1.3 1.3
Shortness of breath walking on level ground 1.8 2.2 4.7 -0.3 1.4 1.5 1.6 -0.7 1.3 1.5 0.8 2.0 1.9 0.5 1.9 1.5 1.7 0.1 1.6 1.3 -0.4 2.2 1.0 1.6 1.9 2.0 0.3 2.0 0.8 1.3 2.1 2.0
Qualifications: College or University degree 2.3 7.3 19.4 0.7 -0.9 -1.5 -0.5 1.3 -2.1 -3.7 1.6 -3.2 -2.2 -3.9 -2.5 -2.6 -4.2 -1.5 -2.9 -1.1 -0.9 -1.9 -1.6 -4.3 -4.4 -4.0 -0.6 -3.6 -3.0 -2.8 -3.7 -3.0
Eye problems/disorders: None of the above 0.6 0.7 5.1 2.2 1.0 0.4 0.2 -0.8 -0.4 1.1 0.9 -0.7 0.0 -1.2 0.4 -0.3 -1.4 -1.6 0.4 -0.1 -1.6 0.2 1.3 0.1 -0.4 -0.4 -0.3 -0.1 0.5 -0.2 -0.1 0.1
Mouth/teeth dental problems: Loose teeth 1.0 1.2 4.7 0.4 0.4 0.8 1.8 -0.4 2.2 1.3 0.4 1.4 1.3 1.5 1.2 0.5 1.0 0.1 0.9 -0.1 -1.0 0.8 0.7 1.4 1.5 1.5 0.2 1.3 0.9 1.0 1.3 1.1
Emphysema/chronic bronchitis 4.3 4.8 12.9 1.6 2.5 3.6 2.3 -1.0 2.5 1.3 2.0 2.8 2.5 0.9 2.8 1.9 1.3 -1.1 2.5 2.5 -1.6 2.9 2.3 2.1 2.0 2.2 0.6 2.3 2.2 2.0 2.5 2.7
Medication for pain relief, constipation, heartburn 1.5 2.6 8.5 1.7 -1.1 -1.9 -0.2 1.4 -0.7 -1.8 -0.6 -2.0 -1.4 -2.3 -1.1 -1.5 -2.0 -2.3 -1.0 -1.3 -0.8 -1.3 -0.9 -1.5 -1.8 -1.6 -2.9 -1.5 -1.8 -2.3 -1.7 -1.5
Neck or shoulder pain in last month 0.4 0.6 3.2 -1.5 -1.0 -0.7 -0.5 0.8 -0.2 0.1 -1.8 0.1 -0.1 0.1 -0.6 -0.7 0.9 1.3 -0.6 -1.1 1.1 -0.5 -1.1 -0.2 0.2 0.0 0.5 -0.2 -0.4 0.3 -0.1 -0.3
Medication: Blood pressure 0.5 0.8 3.8 1.2 -0.0 0.3 0.0 -1.2 -0.9 -0.4 0.8 -0.8 -0.2 -1.0 0.1 -0.8 -1.9 -1.4 -0.1 0.4 -1.9 -0.1 -0.6 -0.8 -1.1 -0.9 -1.3 -0.7 -0.9 -0.9 -0.8 -0.4
Angina (self-reported) 0.4 0.5 2.0 0.7 0.8 0.4 -0.1 -0.7 0.2 0.8 -0.6 0.8 0.7 1.4 0.4 1.1 0.9 0.1 0.6 0.8 0.0 0.8 0.9 0.3 0.5 0.6 0.6 0.6 0.7 1.0 0.6 0.7
Migraine (self-reported) 6.5 8.1 14.8 -0.6 -2.8 -3.0 -3.5 1.7 -3.8 -2.8 -2.6 -3.4 -3.3 -2.6 -3.3 -3.4 -2.7 -0.3 -3.1 -2.7 0.7 -2.9 -2.8 -3.1 -3.1 -3.2 -1.4 -3.3 -2.9 -3.0 -3.1 -3.1
Medication: Ibuprofen 0.5 0.6 2.2 -0.4 -0.2 0.6 1.1 -1.0 1.4 0.7 0.1 1.4 1.1 0.8 0.4 0.5 1.5 0.8 0.3 0.2 0.2 0.4 0.3 0.5 0.7 0.5 0.6 0.5 0.9 0.9 0.7 0.6
Medication: Allopurinol 2.8 3.7 6.8 0.9 2.3 2.4 1.4 -1.2 1.4 1.9 1.2 2.0 1.9 1.4 2.4 2.1 1.9 -0.1 2.4 0.7 -0.7 2.0 2.0 2.6 2.5 2.5 0.6 2.5 2.2 2.1 2.4 2.4
Medication: Omeprazole 0.6 0.8 5.3 -2.3 0.7 0.2 -0.6 -0.1 -0.5 -0.1 0.4 0.6 0.4 0.2 0.5 0.1 1.0 2.0 0.4 1.1 0.8 0.6 -0.5 0.6 0.7 0.8 1.6 0.7 0.5 1.2 0.6 0.5
Medication: Seretide 50 evohaler 4.6 5.2 22.8 3.2 2.3 2.5 2.9 -2.6 2.2 1.1 4.0 2.0 2.6 -0.4 2.9 1.3 -0.3 -3.1 2.4 2.1 -4.8 2.9 1.2 1.2 1.0 1.5 -0.5 1.8 1.1 1.5 1.8 2.2
Mean time to correctly identify matches 0.4 0.8 2.3 0.2 -1.5 -1.4 0.2 0.3 0.0 0.8 -0.1 -1.1 -0.7 -0.8 -0.6 -1.4 -0.8 -0.2 -0.7 -1.3 -0.6 -1.2 -0.8 -0.4 -0.7 -0.9 -1.4 -0.9 -0.8 -1.3 -0.9 -1.0
Heart disease (mother) 0.7 0.9 4.4 -1.7 -1.1 -0.6 -1.2 0.9 -1.1 -1.0 -0.8 -0.5 -0.7 0.4 -1.0 -0.2 -0.2 1.4 -1.0 -0.0 2.1 -0.9 -1.1 -0.6 -0.4 -0.6 -0.2 -0.6 -0.9 -0.7 -0.7 -0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 3.8 1.0 -0.5 0.1 0.5 -0.4 0.4 0.7 -1.1 0.1 -0.2 0.9 0.7 -0.6 -0.3 -1.0 0.6 -1.2 -1.1 -0.2 -0.4 0.9 0.5 0.5 -1.9 0.4 0.1 -0.3 0.3 0.2
Whole body fat mass 1.2 5.2 21.6 -3.2 -0.6 -1.6 -4.5 1.0 -4.7 -2.1 -1.5 -2.5 -2.1 -3.5 -2.0 -1.9 -1.5 2.9 -1.9 -0.3 2.2 -1.7 -2.4 -1.7 -1.9 -1.9 1.7 -1.9 -1.9 -0.9 -2.0 -2.1
Leg fat mass (right) 1.3 5.2 18.7 -2.6 -0.8 -1.5 -4.1 1.0 -4.3 -2.6 -1.2 -2.5 -2.0 -4.0 -1.9 -2.4 -1.9 1.9 -1.9 -0.6 1.2 -1.6 -2.7 -2.1 -2.4 -2.2 1.0 -2.2 -2.3 -1.2 -2.3 -2.2
Arm predicted mass (right) 2.9 15.0 36.0 -0.9 -1.8 -3.4 -2.9 1.3 -4.3 -4.4 -1.0 -4.7 -3.6 -6.0 -3.5 -4.2 -4.8 -0.6 -3.8 -1.9 -0.4 -3.1 -3.6 -5.4 -5.9 -5.3 -1.0 -4.9 -4.8 -4.0 -5.2 -4.5
Pulse rate, automated reading 0.4 1.3 4.8 -0.5 0.7 1.3 -1.8 -1.1 -0.7 0.4 -0.2 0.9 1.0 0.6 0.3 1.4 1.9 1.3 0.7 1.5 0.8 1.1 0.6 0.9 1.3 1.1 2.2 1.0 1.4 1.5 1.4 1.2
Alcohol intake frequency. 0.2 0.4 3.0 -0.7 -1.2 -0.4 -1.0 -0.6 0.4 -0.0 0.0 0.3 0.2 0.3 0.1 -1.2 1.7 0.5 0.2 -1.1 -0.2 -0.2 -1.1 0.5 0.6 0.5 -0.5 0.3 0.2 0.7 0.3 0.1
Comparative height size at age 10 0.9 4.9 23.8 -4.8 0.9 -0.2 -2.6 0.1 -3.3 -2.2 -0.0 -1.5 -1.5 -0.9 -1.2 0.6 -1.4 4.9 -1.4 3.1 3.6 -0.9 -1.1 -1.6 -1.9 -1.6 4.4 -1.2 -1.0 0.1 -1.9 -1.6
Number of full sisters 1.1 1.3 3.8 -0.3 1.0 0.3 1.1 -1.7 1.1 1.7 1.1 0.8 1.2 0.4 1.3 0.1 0.6 0.6 1.1 1.1 -1.0 1.4 0.8 1.2 1.2 1.1 1.6 1.2 1.4 1.9 1.3 1.3
Suffer from ‘nerves’ 2.0 3.1 9.7 -0.4 0.4 1.1 1.9 -1.0 1.6 2.3 0.7 2.0 1.4 2.8 1.5 1.7 3.1 1.4 1.8 0.2 1.3 0.9 1.1 2.5 2.6 2.5 0.1 2.3 2.0 1.5 2.0 1.7
Overall health rating 1.7 3.6 6.5 -1.8 1.8 1.6 0.7 -1.5 0.7 2.2 1.1 2.3 2.1 1.8 1.7 1.8 2.5 2.6 1.7 2.2 1.7 1.8 1.2 1.8 2.1 2.2 2.5 2.2 1.7 2.3 2.0 1.9
Chest pain or discomfort 7.4 10.6 22.2 1.1 3.3 3.4 4.0 -2.1 3.8 2.6 2.4 4.7 4.1 3.3 3.7 3.8 3.5 -0.6 3.4 3.1 -1.3 3.9 3.4 3.0 3.4 3.5 1.3 3.6 2.8 3.3 3.8 3.9
Had major operations 0.6 0.7 2.7 1.0 1.6 1.1 -0.2 -0.3 -0.4 0.1 -0.0 0.6 1.2 -1.1 1.2 0.7 -0.5 -0.4 1.2 1.4 -0.8 1.0 1.0 0.6 0.1 0.3 0.5 0.5 0.8 0.8 0.4 0.7
Age at last live birth 1.2 1.8 3.7 -0.9 -0.8 -0.6 -1.5 1.5 -1.9 -1.9 -0.9 -1.6 -1.5 -0.9 -1.7 -0.6 -1.6 0.9 -1.6 -0.3 1.4 -1.1 -0.6 -1.8 -1.7 -1.6 0.8 -1.5 -1.2 -1.2 -1.6 -1.5
Family relationship satisfaction 0.4 0.5 3.7 -1.6 0.5 0.8 1.0 1.1 0.9 -0.2 1.1 0.6 0.7 -0.4 0.2 0.2 0.0 1.2 -0.3 0.6 0.1 0.6 -0.0 -0.3 0.0 0.0 1.9 0.0 0.1 0.5 0.2 0.3
Leg pain on walking 0.8 1.0 2.6 -0.7 0.8 1.5 1.5 -1.0 1.0 0.9 1.6 1.3 1.2 0.5 1.1 1.0 1.1 0.7 0.9 1.3 -0.4 1.1 0.8 0.6 0.6 0.7 1.0 0.8 0.7 0.9 0.8 0.9
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 4.2 0.4 -0.1 -0.7 -0.5 -0.2 -0.6 0.1 -1.1 -1.4 -1.0 -1.9 -0.8 -2.0 -1.3 -0.7 -0.9 -1.1 -1.1 -0.5 -0.7 -1.4 -1.6 -1.6 -0.1 -1.4 -1.0 -0.8 -1.2 -1.0
Commuting to job workplace: Car/motor vehicle 0.4 0.4 2.4 0.5 0.2 0.8 0.7 -0.5 1.1 -0.1 1.6 0.9 1.1 -0.2 0.8 -0.7 0.4 -1.0 0.3 -0.3 -1.1 0.9 -0.7 -0.2 -0.0 0.0 -0.4 0.0 -0.3 -0.0 0.4 0.5
Illness, injury, bereavement, stress in last 2 years 1.4 1.7 4.6 2.1 -0.8 -0.8 -2.1 0.5 -2.0 -0.7 -1.5 -1.9 -1.7 -0.9 -1.5 -0.8 -1.6 -1.6 -0.9 -1.2 -0.9 -1.2 0.2 -1.0 -1.2 -1.2 -1.6 -1.1 -0.7 -1.5 -1.2 -1.1
Medication: Aspirin 1.3 1.7 6.7 -1.9 0.8 1.8 -0.0 -0.8 0.6 0.8 0.8 1.3 0.7 2.1 0.4 1.3 1.6 2.1 0.5 1.5 1.3 0.8 0.8 1.0 1.3 1.1 2.6 1.1 1.4 1.8 1.2 1.1
Supplements: Vitamin C 0.3 0.3 1.9 -0.1 -1.0 -0.0 0.7 0.3 1.4 1.0 -1.0 0.2 -0.3 1.1 -0.1 -0.1 0.3 0.4 -0.1 -0.4 0.4 -0.8 0.2 0.8 0.6 0.2 -0.5 0.1 0.4 -0.2 0.1 -0.1
Knee pain experienced in last month 1.2 1.8 6.5 -1.4 0.8 1.3 0.8 -0.6 1.2 0.4 -0.5 2.0 1.6 1.8 1.1 1.5 2.5 1.6 1.1 1.0 0.4 1.2 -0.0 1.1 1.4 1.5 1.7 1.5 1.0 1.9 1.3 1.3
Hypertension (Self-reported) 0.2 0.6 3.3 -0.7 -0.6 0.0 -0.3 -0.0 -0.7 -1.0 -0.2 -1.0 -1.0 -0.7 -0.4 -0.8 -1.8 0.1 -0.6 0.6 -0.0 -0.7 -0.7 -0.8 -1.2 -1.1 -0.2 -1.0 -0.8 -0.8 -1.1 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.6 -0.2 0.5 0.6 0.5 0.2 0.2 -0.7 0.6 0.1 0.2 0.0 0.3 -0.0 -0.1 -0.3 0.3 0.6 -0.2 0.7 -0.0 -0.0 0.2 0.3 0.1 0.3 -0.2 0.3 0.4 0.5
Illnesses of father: Heart disease 0.2 0.3 2.3 -0.3 0.9 1.5 -0.8 -0.3 -0.3 0.2 0.5 0.5 0.6 -0.5 0.5 -0.1 0.4 0.4 0.4 0.2 0.3 0.6 0.3 0.2 0.1 0.2 1.1 0.4 0.7 0.7 0.3 0.5
Illnesses of siblings: Diabetes 3.6 4.4 10.4 1.3 1.4 2.0 2.6 -2.3 2.6 3.0 1.7 2.5 3.2 1.2 2.8 1.1 1.9 -0.6 2.5 0.7 -1.2 2.6 0.9 2.2 2.4 2.5 0.1 2.5 1.7 2.1 2.6 2.6
Smoking status: Previous 0.4 0.6 3.9 0.4 -1.3 -0.4 0.1 1.6 1.1 -0.8 0.1 0.8 -0.1 1.4 -0.0 0.1 0.8 -1.0 -0.2 -1.2 -0.2 -0.8 -0.4 0.4 0.6 0.3 -2.0 0.1 -0.2 -0.6 0.1 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 5.2 -0.1 0.5 -0.4 -1.4 -0.0 -2.3 0.0 -2.0 -1.2 -0.9 -1.1 -0.7 -0.2 -1.1 0.5 -0.5 0.1 0.8 -0.1 0.0 -0.9 -0.9 -0.7 1.0 -0.6 -0.6 -0.3 -0.8 -0.6
Whole body fat-free mass 2.7 15.3 37.3 -0.5 -1.6 -3.1 -2.9 1.2 -4.3 -4.4 -0.7 -4.8 -3.7 -6.1 -3.6 -4.3 -4.9 -0.9 -3.9 -1.7 -0.8 -3.1 -3.5 -5.6 -6.1 -5.5 -1.0 -5.1 -4.8 -3.9 -5.3 -4.5
Leg fat-free mass (right) 2.3 12.3 29.8 -0.1 -1.8 -2.8 -2.6 1.1 -3.8 -3.9 -0.7 -4.3 -3.4 -5.5 -3.3 -4.1 -4.0 -1.1 -3.5 -2.1 -1.1 -2.9 -3.5 -4.9 -5.3 -4.8 -1.2 -4.5 -4.2 -3.5 -4.6 -4.1
Arm fat percentage (left) 0.9 3.8 18.7 -2.1 -1.3 -1.3 -4.3 1.3 -3.9 -2.0 -1.5 -2.0 -1.8 -3.1 -1.8 -2.2 -0.9 1.5 -1.6 -1.5 1.1 -1.5 -2.5 -1.2 -1.3 -1.4 0.4 -1.6 -1.6 -0.9 -1.5 -1.7
Average weekly red wine intake 1.9 2.7 9.4 2.5 1.9 2.2 2.0 -1.4 1.4 1.7 1.2 1.6 1.5 1.2 1.7 1.8 1.1 -1.4 1.9 1.5 -1.3 1.6 3.1 1.4 1.1 1.0 0.3 1.2 2.2 1.3 1.5 1.7
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.2 0.2 0.3 0.4 -0.5 0.7 -0.3 0.7 0.1 0.5 0.5 0.1 0.5 0.7 0.3 -0.3 0.7 0.1 -0.4 0.6 1.0 0.5 0.4 0.3 0.4 0.4 1.1 0.7 0.6 0.7
Mood swings 0.7 1.2 9.2 -2.2 -0.2 0.6 0.2 -0.1 0.1 1.1 -1.6 0.9 0.1 1.4 0.1 0.6 1.7 2.3 0.1 -0.1 3.0 -0.3 0.1 0.8 1.0 0.8 1.0 0.6 0.6 0.7 0.5 0.3
Loneliness, isolation 2.1 2.9 6.6 -1.5 0.9 1.1 0.9 -1.4 0.7 1.8 0.1 1.7 1.3 2.2 1.5 2.1 2.6 1.9 1.7 1.5 1.2 1.1 1.0 2.2 2.3 2.2 1.6 2.1 2.1 2.2 1.8 1.6
Long-standing illness, disability or infirmity 0.4 0.6 3.1 0.2 0.7 0.3 1.8 -0.8 1.3 0.9 1.6 0.7 0.8 0.8 0.9 0.7 0.1 0.0 0.8 0.9 -0.2 0.3 0.5 0.7 0.4 0.6 0.0 0.7 0.6 0.6 0.3 0.5
Ever had bowel cancer screening 0.1 0.1 0.4 0.4 0.1 0.4 -0.4 -0.0 -0.1 -0.2 -0.0 -0.2 -0.3 0.1 0.1 -0.2 0.1 -0.4 0.4 0.1 -0.6 0.0 0.5 -0.1 -0.5 -0.4 -0.2 -0.1 0.3 0.2 -0.3 -0.0
Diabetes diagnosed by doctor 0.8 1.4 5.1 -1.3 1.1 1.1 -0.2 -1.7 -0.6 0.6 0.3 1.0 0.7 1.7 0.6 1.6 1.1 1.4 0.9 2.2 1.3 1.1 0.4 0.9 1.2 1.4 1.5 1.3 0.7 1.3 1.1 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 2.1 -1.4 0.3 0.2 0.2 0.6 -0.2 -0.6 -0.3 -0.0 -0.4 0.5 -0.2 0.3 -0.3 1.4 -0.3 0.5 1.4 -0.2 0.5 -0.1 -0.1 -0.2 1.2 -0.2 0.3 0.1 -0.1 -0.2
Friendships satisfaction 0.3 0.4 3.5 -0.9 -0.4 0.4 1.9 0.2 1.1 -0.3 1.1 0.4 0.1 -0.0 0.1 -0.2 -0.6 0.1 -0.5 -0.0 -0.6 -0.1 -0.6 -0.8 -0.6 -0.4 -0.0 -0.3 -0.7 -0.4 -0.5 -0.2
Qualifications: nursing, teaching 1.1 1.8 3.9 -0.3 -1.8 -1.1 1.9 1.0 0.9 -2.0 0.3 -0.6 -0.8 -0.4 -0.9 -0.9 -0.5 -0.3 -1.3 -1.6 0.2 -1.8 -1.8 -1.5 -1.4 -1.3 -1.8 -1.3 -1.7 -1.8 -1.7 -1.7
Commuting to job workplace: Walk 0.6 0.7 1.5 -0.1 -0.7 -0.1 0.8 1.2 0.5 -0.9 -0.5 -0.7 -0.8 -0.8 -0.8 -0.5 -1.2 -0.2 -1.1 -0.9 -0.1 -1.0 -0.6 -1.0 -1.0 -1.1 0.0 -1.1 -0.6 -0.8 -1.0 -1.0
Eye problems/disorders: Cataract 0.3 0.3 1.7 -1.3 -0.8 -0.4 -0.1 0.8 0.5 -0.3 -1.3 0.2 -0.3 0.4 -0.4 -0.4 0.3 0.8 -0.5 -0.3 1.1 -0.3 -0.7 0.1 0.4 0.2 0.2 -0.1 -0.5 -0.2 0.2 -0.2
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 4.3 0.1 -1.2 -1.6 0.1 1.5 -0.2 -0.3 0.6 -0.9 -0.6 -0.7 -1.1 -1.0 -0.8 -0.7 -1.1 -2.1 0.0 -0.9 -1.2 -1.3 -1.1 -1.1 -0.6 -1.1 -0.9 -1.0 -1.0 -1.0
Medication for cholesterol 1.3 1.9 7.8 2.8 1.5 0.8 0.3 -1.7 -0.0 2.0 0.6 0.8 1.5 0.1 1.3 1.2 1.8 -1.7 1.8 -0.2 -1.4 1.4 1.4 1.5 1.5 1.7 -0.7 1.7 1.0 1.0 1.5 1.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.8 3.2 6.6 -0.1 1.9 2.2 1.2 -0.4 1.5 1.7 1.0 2.6 2.3 1.6 2.0 2.3 2.2 0.7 2.0 1.8 -0.2 2.1 1.6 1.8 1.9 1.9 1.6 2.0 1.9 2.1 2.1 2.1
Back pain experienced in last month 0.5 0.8 5.3 -1.7 0.1 -0.3 0.3 -0.4 0.2 0.7 -1.0 0.2 0.1 0.4 -0.5 0.3 1.5 2.3 -0.4 0.4 2.0 -0.3 0.1 -0.2 0.1 0.0 2.0 0.0 0.3 0.6 -0.1 -0.2
Mineral and other dietary supplements 0.2 0.3 0.8 -0.7 -0.6 -0.7 0.6 -0.4 0.5 0.2 0.2 0.5 0.2 0.9 0.3 0.5 0.9 0.5 0.2 0.2 0.0 -0.2 -0.7 0.6 0.8 0.7 -0.5 0.6 0.2 0.3 0.4 0.2
Breast cancer (self-reported) 0.9 1.0 2.2 0.6 1.0 1.4 0.3 -1.1 1.4 0.4 0.7 1.4 1.1 1.1 1.0 0.8 1.4 -0.2 1.1 0.5 -0.0 1.2 0.4 1.0 1.3 1.5 0.3 1.3 0.6 1.2 1.3 1.1
Asthma (self-reported) 1.2 2.3 13.3 3.0 0.2 1.2 2.7 -0.1 3.0 0.1 1.4 1.3 1.5 -0.5 1.4 0.1 0.0 -3.3 1.1 0.1 -3.6 1.2 0.7 0.3 0.1 0.2 -1.7 0.4 0.8 0.1 0.7 1.0
Osteoporosis (self-reported) 1.8 2.3 6.5 1.4 2.1 2.5 -0.3 -1.0 -0.3 0.8 -0.2 1.8 1.6 1.5 1.4 2.0 1.3 -0.9 1.8 1.9 -0.5 2.2 1.7 1.2 1.5 1.7 0.2 1.7 1.0 1.2 1.9 2.0
Osteoarthritis (self-reported) 0.9 1.1 2.7 -1.0 -1.4 -1.0 -1.1 0.2 -1.1 -1.3 -0.6 -1.1 -1.2 -0.9 -1.2 -1.6 -0.2 0.5 -1.1 -1.1 0.7 -1.5 -1.4 -0.7 -0.8 -0.9 -0.9 -1.0 -1.1 -0.9 -1.1 -1.2
Medication: Aspirin 1.4 1.9 7.1 -2.2 0.7 1.8 -0.3 -0.5 0.6 0.5 0.3 1.4 0.7 1.9 0.4 1.3 1.8 2.4 0.5 1.4 1.8 0.6 0.8 1.1 1.4 1.2 2.7 1.1 1.5 1.9 1.1 1.0
Medication: Gliclazide 0.4 0.4 2.2 0.3 0.3 0.2 -0.1 -1.4 -0.6 0.0 -1.3 -0.2 -0.3 1.5 0.0 0.8 0.5 0.2 0.5 0.5 1.2 0.2 0.3 0.7 0.8 0.8 -0.3 0.7 0.3 0.3 0.5 0.5
Illnesses of father: None of the above (group 1) 0.7 0.9 3.6 1.0 -1.0 -1.5 0.3 -0.4 -0.5 -0.1 -1.3 -0.9 -0.7 -0.3 -0.6 -0.6 -1.4 -1.1 -0.6 -0.5 -1.5 -0.6 -1.1 -0.7 -0.7 -0.6 -1.9 -0.7 -1.2 -1.0 -0.7 -0.6
Smoking status: Current 0.6 0.9 7.1 -1.8 1.0 1.1 -0.5 -0.4 -0.7 0.4 -0.6 0.4 0.3 -0.0 0.5 0.7 0.3 1.9 0.5 1.4 0.2 1.0 0.8 0.3 0.2 0.3 2.7 0.4 1.1 1.5 0.6 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 2.9 6.2 0.2 -1.8 -2.0 -2.5 1.6 -1.9 -1.9 -1.5 -2.1 -1.7 -2.0 -2.2 -1.9 -0.8 -0.4 -1.8 -2.1 1.2 -1.8 -1.4 -1.6 -1.4 -1.5 -1.3 -1.7 -1.7 -1.9 -1.6 -1.7
Whole body water mass 2.9 16.3 38.9 -0.5 -1.9 -3.3 -2.9 1.4 -4.3 -4.5 -0.9 -4.9 -3.8 -6.2 -3.8 -4.5 -5.0 -1.0 -4.1 -1.9 -0.9 -3.2 -3.6 -5.8 -6.2 -5.7 -1.2 -5.2 -4.9 -4.1 -5.4 -4.7
Leg predicted mass (right) 2.3 12.2 29.3 -0.2 -1.8 -2.8 -2.6 1.1 -3.8 -3.9 -0.7 -4.2 -3.4 -5.4 -3.3 -4.0 -4.1 -1.0 -3.5 -2.0 -1.1 -2.9 -3.5 -4.9 -5.3 -4.8 -1.2 -4.5 -4.2 -3.5 -4.6 -4.1
Arm fat mass (left) 2.0 8.2 23.2 -2.4 -1.6 -2.1 -4.8 1.6 -4.8 -3.1 -1.8 -3.3 -2.8 -4.6 -2.8 -3.3 -2.4 1.4 -2.8 -1.7 1.1 -2.4 -3.4 -2.9 -3.1 -3.1 0.3 -3.1 -2.9 -2.1 -3.0 -3.0
Number of self-reported non-cancer illnesses 0.8 1.4 5.2 -0.7 1.0 1.7 1.0 -0.4 0.8 0.1 2.3 1.5 1.2 1.2 1.5 1.1 0.9 0.6 1.4 1.6 0.5 1.1 0.7 1.3 1.2 1.3 0.6 1.4 1.3 1.0 1.1 1.2
Average weekly champagne plus white wine intake 1.7 2.4 7.4 -2.7 -2.0 -1.6 -1.4 2.4 -0.9 -1.3 -2.4 -0.8 -1.2 -0.5 -1.6 -1.1 0.2 1.6 -1.8 -2.3 2.1 -1.6 -1.8 -1.1 -0.7 -1.0 -0.5 -1.3 -1.6 -1.3 -1.0 -1.3
Miserableness 2.2 3.8 6.3 -0.7 2.1 2.3 1.5 -1.6 1.5 2.5 0.3 2.4 2.0 1.9 1.9 1.9 2.4 1.1 2.0 1.4 1.0 1.9 1.9 2.1 2.3 2.3 1.9 2.3 2.3 2.4 2.2 2.2
Guilty feelings 3.5 5.2 12.2 0.1 2.4 2.0 3.0 -2.0 3.1 3.5 1.4 2.3 2.2 1.7 2.7 2.2 2.0 0.6 2.6 2.0 -0.5 2.2 2.7 2.8 2.3 2.1 1.7 2.3 2.9 2.7 2.5 2.4
Wears glasses or contact lenses 0.5 0.6 2.6 -0.6 -0.9 -0.5 -1.5 -0.0 -1.6 -0.8 -0.3 -0.7 -0.6 -0.9 -0.6 -0.9 -0.1 0.4 -0.6 0.0 0.2 -0.8 -1.2 -0.6 -0.9 -0.8 -0.2 -0.8 -0.9 -0.8 -1.0 -0.9
Ever taken oral contraceptive pill 1.2 1.3 4.8 1.1 1.4 1.0 1.6 -0.1 1.5 0.9 1.7 1.4 1.4 0.1 1.4 0.8 1.3 -0.3 1.5 0.2 -0.5 0.9 2.2 1.1 0.8 0.8 0.7 1.0 1.7 1.2 0.9 1.1
Hearing aid user 0.5 0.5 2.9 1.1 1.0 0.9 0.7 -0.7 0.5 1.1 0.6 0.4 0.6 -0.4 1.1 -0.1 -0.2 -0.9 0.8 -0.3 -1.7 0.8 0.7 0.6 0.3 0.3 0.3 0.4 0.6 0.6 0.5 0.7
Mother’s age at death 1.1 1.4 7.3 -1.7 -0.5 -0.8 -0.9 1.2 -1.1 -1.3 -1.6 -1.1 -1.4 0.8 -1.5 0.1 -0.3 1.5 -1.3 0.4 2.7 -1.1 -0.5 -1.1 -0.9 -1.0 1.0 -1.0 -0.7 -0.8 -1.1 -1.2
Financial situation satisfaction 1.3 1.6 3.3 -1.2 1.2 1.7 1.1 0.6 1.6 0.9 1.0 1.5 1.3 0.8 1.4 1.0 0.8 1.1 1.1 1.0 0.2 1.6 1.3 1.3 1.4 1.4 1.8 1.4 1.4 1.5 1.5 1.5
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.5 1.0 -0.0 0.2 1.2 0.5 0.8 0.3 0.2 0.6 0.2 0.1 0.6 -0.3 0.1 -1.0 0.4 -0.9 -1.2 0.0 0.2 0.4 0.2 0.3 -0.9 0.3 0.4 -0.0 0.2 0.2
Commuting to job workplace: Public transport 0.5 0.6 3.0 -0.6 -0.8 -1.0 -0.1 1.7 -0.3 -1.1 0.1 -1.0 -0.7 -0.8 -0.7 -0.3 -1.1 -0.1 -0.7 -0.7 -0.1 -0.7 -0.7 -0.7 -0.8 -0.8 -0.5 -0.8 -0.6 -0.7 -0.8 -0.8
Eye problems/disorders: Glaucoma 0.5 0.6 2.1 -1.0 -0.8 -0.8 -1.1 -0.2 -1.2 -1.5 0.1 -0.5 -0.6 -0.2 -0.6 0.3 -0.4 0.9 -0.6 0.7 1.1 -0.7 -1.2 -0.7 -0.7 -0.5 -0.2 -0.5 -0.7 -0.3 -0.9 -0.8
Medication: Blood pressure 1.1 2.1 7.2 -2.7 -1.7 -1.1 -0.4 1.3 -0.4 -1.8 -0.6 -1.4 -1.7 -0.7 -1.3 -1.4 -1.9 1.9 -1.6 -0.2 1.5 -1.7 -1.4 -1.2 -1.5 -1.7 0.4 -1.6 -1.1 -1.1 -1.6 -1.7
Pain type(s) experienced in last month: Hip pain 0.4 0.5 3.2 -0.6 -0.6 0.5 0.8 0.3 1.4 0.3 -1.2 0.9 0.5 1.8 0.2 0.4 1.3 1.0 0.2 -0.4 0.2 -0.4 -0.0 0.6 0.7 0.6 0.2 0.5 0.4 0.6 0.2 0.1
Supplements: Fish oil (including cod liver oil) 0.9 1.1 3.7 1.2 1.6 1.9 0.6 -0.2 1.0 1.1 0.3 1.0 1.2 0.6 1.2 0.7 0.7 -0.9 1.3 0.0 0.0 1.3 1.9 1.1 1.0 1.0 0.3 1.0 1.1 0.9 1.3 1.3
High cholesterol (Self-reported) 0.5 0.9 6.5 -2.4 -0.6 0.0 -0.1 0.2 0.2 -1.1 0.2 0.9 0.0 2.6 0.2 0.7 1.0 2.0 0.0 0.4 1.5 -0.3 -0.7 0.6 0.9 0.8 0.5 0.6 0.2 0.7 0.4 0.2
Medication: Bendroflumethiazide 1.3 2.0 7.2 -1.6 -1.1 -1.0 -0.0 1.3 -0.2 -2.1 0.5 -1.5 -1.3 -1.3 -1.0 -1.6 -2.7 0.5 -1.5 -0.1 0.0 -1.1 -1.4 -1.7 -2.0 -2.0 -0.2 -1.9 -1.6 -1.7 -1.7 -1.6
Medication: Paracetamol 0.7 1.2 3.8 -0.9 1.0 0.9 -0.1 -0.4 0.2 1.4 0.8 0.9 0.7 0.9 0.9 0.9 1.2 1.1 1.1 0.7 0.2 1.1 1.0 1.2 1.2 1.0 1.9 1.1 1.6 1.9 1.3 1.1
Medication: Lisinopril 0.3 0.4 2.7 0.0 0.7 1.2 -0.1 -1.0 -0.0 -0.6 1.1 0.0 0.2 -0.5 0.6 0.0 -0.9 -0.3 0.3 1.6 -1.5 0.5 -0.1 -0.3 -0.6 -0.4 0.2 -0.2 -0.3 0.2 -0.3 0.1
Medication: Atorvastatin 0.9 1.2 3.0 -0.6 0.7 0.7 -0.4 -1.2 0.1 1.0 0.0 0.7 0.9 1.6 0.7 1.5 1.0 1.3 0.9 1.7 0.1 1.1 0.3 1.1 1.4 1.5 1.2 1.4 0.9 1.5 1.3 1.2
Illnesses of father: High blood pressure 0.7 0.9 3.0 -0.8 -1.1 -0.8 -0.8 1.7 -0.8 -1.4 -0.6 -1.0 -1.5 -0.7 -1.1 -0.8 -0.8 0.5 -1.0 -1.3 1.3 -1.3 -0.3 -0.6 -0.6 -0.8 -0.3 -0.9 -0.2 -0.9 -0.8 -1.0
Alcohol drinker status: Never 1.2 1.4 3.9 0.9 1.4 1.3 -0.1 -1.6 0.5 0.2 0.4 1.6 1.2 2.0 1.3 1.0 1.7 -0.3 1.5 0.8 0.1 1.3 1.1 1.0 1.2 1.4 0.2 1.4 1.1 1.5 1.3 1.4
Ever smoked 0.3 0.5 2.6 -1.5 -1.4 -0.7 0.3 1.6 0.8 -0.4 -0.8 0.3 -0.5 1.1 -0.5 -0.1 0.8 0.9 -0.7 -0.8 1.1 -0.8 -0.2 0.0 0.3 0.0 -0.2 -0.2 -0.1 -0.2 -0.1 -0.4
Basal metabolic rate 2.6 14.7 38.4 -0.9 -1.6 -3.0 -3.3 1.3 -4.6 -4.3 -0.8 -4.7 -3.6 -6.2 -3.5 -4.2 -4.7 -0.5 -3.8 -1.6 -0.5 -3.0 -3.5 -5.3 -5.8 -5.3 -0.7 -4.9 -4.6 -3.7 -5.1 -4.4
Leg fat percentage (left) 0.7 2.5 16.4 -2.8 -0.6 -0.7 -4.0 0.4 -3.7 -1.2 -1.4 -1.3 -1.2 -2.1 -0.9 -1.2 -0.2 2.5 -0.7 -0.2 2.1 -0.9 -1.8 -0.2 -0.5 -0.5 1.0 -0.6 -0.9 -0.1 -0.7 -0.9
Arm fat-free mass (left) 3.1 15.7 37.5 -1.2 -1.9 -3.3 -3.2 1.6 -4.4 -4.5 -1.0 -4.7 -3.7 -6.1 -3.5 -4.3 -4.8 -0.5 -3.9 -1.8 -0.3 -3.2 -3.8 -5.5 -6.0 -5.4 -1.2 -5.0 -5.0 -4.1 -5.3 -4.6
Number of operations (self-reported) 0.9 1.4 6.0 -0.9 -1.1 -1.2 -1.0 2.5 -0.1 -1.7 -2.0 -0.4 -0.7 -1.3 -1.0 -1.5 -0.4 0.7 -1.2 -1.4 1.0 -1.1 -1.4 -0.9 -1.0 -1.2 -0.1 -1.3 -0.9 -0.6 -1.0 -1.2
Average weekly beer plus cider intake 2.0 3.0 5.8 0.6 2.3 1.7 1.1 -1.8 1.0 2.1 1.5 1.5 1.7 0.5 2.1 1.5 1.0 0.4 2.0 1.9 -0.7 1.9 2.1 1.9 1.7 1.7 2.3 1.9 2.4 2.3 1.8 1.9
Irritability 0.7 1.1 5.1 -2.2 -0.8 0.4 0.2 0.9 1.0 0.3 -1.2 1.1 0.3 2.1 -0.2 0.9 1.8 2.2 -0.2 -0.5 1.2 -0.4 -0.4 0.7 1.1 0.8 1.4 0.6 0.9 1.0 0.5 0.2
Risk taking 0.4 0.6 2.9 -1.1 0.0 0.9 -0.4 1.7 -0.1 -1.7 -0.8 0.6 0.1 -0.5 -0.7 0.9 -0.6 0.7 -1.0 0.4 0.3 0.2 -0.1 -1.2 -0.7 -0.7 1.4 -0.7 -0.0 0.2 -0.2 -0.2
Ever had prostate specific antigen (PSA) test 0.5 0.6 1.8 1.2 0.1 0.6 0.1 -0.7 1.0 0.8 0.7 0.7 0.7 1.3 0.8 0.2 0.6 -0.6 0.8 -0.2 -0.9 0.0 0.7 1.2 0.9 0.7 -0.6 0.7 1.1 0.4 0.6 0.6
Fractured/broken bones in last 5 years 0.2 0.3 1.2 -0.4 0.4 0.2 -1.1 0.3 -0.7 0.2 -0.4 -0.1 0.1 -1.1 -0.6 -0.1 0.1 0.8 -0.5 0.4 0.5 0.0 -0.1 -0.7 -0.7 -0.8 1.1 -0.7 -0.3 0.0 -0.4 -0.3
Age started oral contraceptive pill 0.7 0.9 4.0 1.6 -0.9 -0.8 0.2 0.1 -0.1 -0.5 -0.5 -1.2 -0.7 -1.1 -0.6 -1.0 -1.0 -1.4 -0.5 -0.9 -0.7 -0.7 -0.3 -0.8 -1.0 -0.9 -2.0 -0.9 -1.1 -1.3 -0.9 -0.8
Diastolic blood pressure, automated reading 3.1 9.7 24.9 -0.7 -2.5 -2.7 -5.0 1.7 -5.0 -3.1 -3.8 -3.7 -3.7 -3.1 -3.7 -2.9 -3.2 -0.0 -3.2 -1.4 2.3 -3.3 -1.7 -3.1 -3.5 -3.6 -1.2 -3.5 -2.7 -3.4 -3.5 -3.4
Ever depressed for a whole week 0.7 0.8 5.6 -2.3 -0.5 -0.4 -1.0 0.7 -0.9 -0.9 0.1 -0.1 -0.7 -0.2 -0.7 -0.0 0.6 2.4 -0.6 0.2 2.1 -0.6 -0.6 -0.2 -0.1 -0.1 1.3 -0.2 0.2 0.3 -0.3 -0.4
Unable to work because of sickness or disability 0.5 0.7 2.9 0.6 0.3 -0.3 1.7 -1.1 1.1 1.4 1.3 0.6 1.1 -0.1 0.9 0.1 0.8 -0.9 0.8 0.2 -1.0 0.8 0.4 0.5 0.4 0.4 -0.8 0.5 0.6 0.5 0.7 0.7
Commuting to job workplace: Cycle 0.3 0.3 2.0 0.2 -0.2 0.4 1.4 -1.0 1.2 0.3 -1.1 -0.5 -0.3 -0.4 0.2 -0.2 -0.8 0.2 0.1 0.4 -0.7 -0.4 0.3 0.1 -0.3 -0.3 0.7 -0.1 0.8 0.6 -0.4 -0.2
Myopia 3.8 5.4 12.9 1.6 -3.1 -2.6 -2.3 1.9 -2.2 -2.0 -3.2 -2.6 -2.7 -0.9 -2.7 -3.0 -1.5 -2.0 -2.1 -3.6 -0.0 -2.7 -1.3 -2.1 -2.1 -2.3 -2.6 -2.4 -1.8 -2.6 -2.4 -2.4
Vascular/heart problems diagnosed by doctor 0.1 0.3 2.0 1.2 0.1 -0.5 -0.4 0.7 -0.0 0.0 -0.3 0.1 0.1 -0.7 -0.1 -0.3 0.8 -1.1 0.1 -1.4 -0.7 0.1 0.0 -0.0 0.1 0.2 -0.7 0.0 -0.1 -0.1 0.2 0.1
Cholesterol lowering medication 0.7 1.0 6.5 -2.5 -0.4 0.2 0.6 0.1 1.4 -0.8 0.6 1.1 0.7 2.0 0.1 0.9 0.8 1.7 -0.3 1.1 1.5 0.4 -1.0 -0.0 0.7 0.7 1.0 0.5 -0.4 0.7 0.6 0.4
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 4.7 -2.2 0.4 -0.1 -1.0 0.0 -0.5 -0.1 0.1 0.3 0.3 -0.4 0.2 -0.6 0.7 1.9 0.0 0.5 0.8 0.4 -0.8 0.4 0.5 0.5 1.5 0.3 0.1 0.8 0.4 0.3
Pain experienced in last month 0.6 1.1 6.8 1.5 -0.2 -0.3 1.0 0.3 0.4 -1.3 1.8 -0.5 -0.5 -0.2 0.2 -0.2 -1.6 -2.4 -0.1 -0.2 -1.5 -0.1 -0.3 -0.4 -0.6 -0.4 -2.6 -0.4 -0.8 -1.4 -0.4 -0.3
Supplements: Calcium 0.7 0.7 2.0 0.7 0.5 0.1 1.0 -0.5 0.7 0.4 -0.1 0.9 0.7 1.3 0.8 1.0 0.6 -0.3 1.1 1.4 -1.0 0.7 1.3 0.9 0.8 0.9 0.1 1.0 1.2 0.9 0.7 0.8
Basal cell carcinoma (self-reported) 0.6 0.7 3.7 1.8 0.7 0.0 1.3 -0.8 0.6 0.8 0.4 0.2 0.9 -0.2 1.2 0.1 -1.1 -1.9 0.7 0.2 -1.8 0.7 0.2 0.4 0.1 0.3 -1.2 0.4 -0.0 -0.2 0.3 0.5
Heart attack/myocardial infarction (self-reported) 2.5 3.2 8.2 -1.6 0.9 1.0 2.1 -1.7 2.1 2.1 0.4 1.7 1.5 2.9 1.4 1.9 2.6 2.4 1.4 1.5 1.6 0.9 1.2 1.9 2.1 2.0 1.7 2.0 1.7 2.0 1.6 1.5
Deep venous thrombosis (DVT) (self-reported) 1.3 1.6 14.5 -2.1 -0.4 -0.9 -1.4 0.9 -1.3 0.4 -1.9 -0.1 -0.8 1.9 -1.1 1.3 0.7 2.7 -0.8 -0.0 3.8 -1.0 0.2 0.2 0.6 0.3 1.1 0.1 -0.1 -0.2 -0.0 -0.4
Heart disease (siblings) 2.9 3.6 6.9 -0.6 1.8 1.7 1.3 -0.9 2.0 2.0 1.8 2.1 2.0 1.7 1.7 1.7 2.2 1.1 1.6 1.8 0.9 1.8 1.9 2.3 2.6 2.5 2.2 2.3 2.2 2.0 2.4 2.1
Alcohol drinker status: Previous 0.9 1.0 6.5 -2.0 -0.4 0.3 -0.3 0.1 0.9 0.5 0.1 1.2 0.9 1.0 0.1 0.8 2.5 1.4 0.3 0.4 0.8 0.6 0.2 0.6 1.1 0.9 1.7 0.7 1.1 1.3 1.0 0.8
Pack years of smoking 1.0 1.5 3.5 -0.9 1.3 1.3 1.3 -1.1 0.9 1.8 1.8 1.1 1.3 0.6 1.2 1.2 0.7 0.9 1.0 1.7 -0.3 1.3 1.2 1.0 0.9 0.8 1.9 0.9 1.6 1.4 1.2 1.2
Impedance of whole body 3.9 19.8 37.9 -3.6 3.8 3.5 0.9 -1.3 1.7 3.7 0.3 4.2 3.2 6.2 3.1 6.1 4.7 5.8 3.6 5.5 4.9 3.3 4.1 5.4 5.9 5.5 6.0 5.2 5.1 4.9 5.0 4.3
Leg fat mass (left) 1.7 6.5 21.5 -2.8 -1.3 -1.9 -4.4 1.1 -4.6 -2.8 -1.6 -2.9 -2.5 -4.1 -2.3 -2.7 -2.0 2.0 -2.3 -1.0 1.6 -2.0 -3.0 -2.3 -2.7 -2.5 0.7 -2.5 -2.6 -1.6 -2.6 -2.6
Arm predicted mass (left) 3.1 16.0 36.8 -1.1 -1.9 -3.3 -3.2 1.5 -4.5 -4.5 -1.1 -4.8 -3.8 -6.0 -3.6 -4.4 -4.8 -0.5 -4.0 -1.8 -0.3 -3.3 -3.9 -5.5 -6.1 -5.5 -1.2 -5.1 -5.0 -4.1 -5.3 -4.7