Best TWAS P=3.52e-10 · Best GWAS P=1.56e-10 conditioned to 0.000792
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | BAIAP2 | 0.36 | 0.01 | enet | 22 | 0.02 | 8.5e-02 | -3.3 | 5.9 | 4.7e-09 | 0.00 | 0.03 | 0.09 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | CBX8 | 0.21 | 0.10 | lasso | 3 | 0.08 | 1.4e-06 | 6.2 | -6.2 | 6.7e-10 | -0.58 | 0.00 | 1.00 | FALSE |
3 | GTEx | Lung | CBX8 | 0.28 | 0.19 | enet | 24 | 0.18 | 1.4e-13 | 6.3 | -6.2 | 5.6e-10 | -0.55 | 0.00 | 1.00 | FALSE |
4 | GTEx | Nerve Tibial | CBX8 | 0.16 | 0.14 | lasso | 4 | 0.14 | 5.3e-10 | 6.1 | -6.3 | 3.5e-10 | -0.59 | 0.00 | 1.00 | TRUE |