Best TWAS P=4.29e-08 · Best GWAS P=4.74e-11 conditioned to 0.0189
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | PDE1A | 0.24 | -0.01 | enet | 21 | -0.01 | 7.6e-01 | -4.6 | -5.2 | 2.2e-07 | -0.60 | 0.07 | 0.32 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | PDE1A | 0.11 | 0.03 | bslmm | 526 | 0.06 | 3.2e-08 | 6.6 | -5.5 | 4.3e-08 | -0.62 | 0.00 | 1.00 | TRUE |