Best TWAS P=5.59e-09 · Best GWAS P=2e-10 conditioned to 0.00463
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | WDR75 | 0.05 | 0.04 | lasso | 2 | 0.03 | 0.0012 | -5.0 | 5.1 | 3.0e-07 | -0.7 | 0.24 | 0.16 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | COL5A2 | 0.04 | 0.00 | blup | 79 | 0.02 | 0.0059 | -6.4 | 5.8 | 5.6e-09 | -0.8 | 0.01 | 0.77 | TRUE |