TWAS
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Genes
Traits
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Traits
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Impedance of arm (right)
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chr3:133,088,362-134,666,475
Best TWAS P=5.96e-11 · Best GWAS P=2.89e-11 conditioned to 2.23e-05
133M
133.2M
133.4M
133.6M
133.8M
134M
134.2M
134.4M
134.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
RYK
0.07
0.00
lasso
3
0.00
0.307
-4.5
-6.5
6.0e-11
0.43
0.06
0.12
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
RYK
0.03
0.01
blup
63
0.01
0.020
-6.6
-6.4
1.8e-10
0.96
0.01
0.92
FALSE
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
RYK
0.09
0.01
blup
63
0.01
0.048
-6.6
-5.9
4.6e-09
0.91
0.01
0.67
FALSE