Best TWAS P=5.96e-11 · Best GWAS P=2.89e-11 conditioned to 2.23e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RYK | 0.07 | 0.00 | lasso | 3 | 0.00 | 0.307 | -4.5 | -6.5 | 6.0e-11 | 0.43 | 0.06 | 0.12 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | RYK | 0.09 | 0.01 | blup | 63 | 0.01 | 0.048 | -6.6 | -5.9 | 4.6e-09 | 0.91 | 0.01 | 0.67 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | RYK | 0.03 | 0.01 | blup | 63 | 0.01 | 0.020 | -6.6 | -6.4 | 1.8e-10 | 0.96 | 0.01 | 0.92 | FALSE |