[Hub]/) : Traits : Impedance of arm (right) :

chr3:134,986,214-137,368,142

Best TWAS P=1.71e-20 · Best GWAS P=1.36e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPP2R3A 0.05 0.02 lasso 4 0.05 7.7e-07 -8.7 -7.1 1.2e-12 0.74 0.03 0.95 FALSE
2 GTEx Adipose Visceral Omentum PPP2R3A 0.08 0.00 enet 17 0.00 3.0e-01 -7.6 -5.2 1.8e-07 0.68 0.11 0.51 TRUE
3 GTEx Artery Aorta PCCB 0.12 0.03 enet 11 0.09 2.0e-05 8.4 -5.3 8.7e-08 -0.01 0.44 0.36 TRUE
4 GTEx Artery Coronary SLC35G2 0.16 0.03 lasso 8 0.05 6.4e-03 -8.3 9.3 1.7e-20 -0.78 0.09 0.62 TRUE
5 GTEx Brain Cerebellar Hemisphere RP11-731C17.2 0.16 0.02 enet 24 0.09 3.0e-03 8.2 -7.6 2.9e-14 0.25 0.20 0.13 TRUE
6 GTEx Brain Cerebellum PPP2R3A 0.28 -0.01 enet 21 0.04 2.9e-02 -8.3 -6.4 1.5e-10 0.55 0.06 0.50 FALSE
7 GTEx Brain Cerebellum RP11-85F14.5 0.13 0.10 lasso 7 0.07 4.1e-03 4.8 -5.5 3.0e-08 0.23 0.54 0.06 FALSE
8 GTEx Brain Cerebellum RP11-731C17.2 0.31 0.05 enet 39 0.12 2.3e-04 4.8 -7.1 1.3e-12 0.42 0.33 0.14 FALSE
9 GTEx Brain Hippocampus RP11-731C17.2 0.19 0.06 enet 24 0.11 1.8e-03 1.5 -5.5 4.9e-08 0.07 0.27 0.13 FALSE
10 GTEx Breast Mammary Tissue (Male) RP11-85F14.5 0.08 0.12 lasso 1 0.06 1.6e-02 -7.2 -7.2 6.5e-13 0.62 0.06 0.28 FALSE
11 GTEx Cells Transformed fibroblasts RP11-85F14.5 0.10 0.08 enet 38 0.09 3.9e-07 4.6 -7.4 1.4e-13 0.48 0.94 0.05 FALSE
12 GTEx Esophagus Mucosa PPP2R3A 0.06 0.06 lasso 3 0.04 9.1e-04 -5.1 -5.1 2.7e-07 0.71 0.43 0.39 FALSE
13 GTEx Esophagus Mucosa RP11-85F14.5 0.13 0.10 lasso 3 0.11 5.1e-08 6.5 -6.5 8.6e-11 0.27 1.00 0.00 FALSE
14 GTEx Esophagus Muscularis RP11-731C17.2 0.16 0.03 enet 13 0.06 1.1e-04 -2.9 -5.9 2.9e-09 0.66 0.20 0.70 FALSE
15 GTEx Lung RP11-85F14.5 0.07 0.05 lasso 19 0.05 8.8e-05 6.5 -6.6 5.1e-11 0.28 0.95 0.01 FALSE
16 GTEx Muscle Skeletal RP11-85F14.5 0.10 0.08 lasso 17 0.09 6.3e-09 4.8 -7.1 1.5e-12 0.54 0.80 0.19 FALSE
17 GTEx Muscle Skeletal RP11-731C17.2 0.15 0.12 lasso 16 0.12 3.8e-12 4.8 -6.8 7.2e-12 0.46 1.00 0.00 FALSE
18 GTEx Skin Sun Exposed Lower leg RP11-85F14.5 0.04 0.01 enet 9 0.03 2.8e-03 4.6 -6.0 1.4e-09 0.35 0.38 0.18 FALSE
19 GTEx Stomach PPP2R3A 0.08 0.02 lasso 4 0.05 1.9e-03 -7.6 5.9 2.8e-09 -0.80 0.13 0.76 FALSE
20 GTEx Testis SLC35G2 0.17 0.19 lasso 10 0.18 1.5e-08 4.6 5.7 1.2e-08 -0.23 1.00 0.00 FALSE
21 GTEx Testis RP11-85F14.5 0.12 0.03 enet 28 0.02 3.8e-02 4.5 -7.0 2.2e-12 0.51 0.37 0.38 TRUE
22 GTEx Thyroid PPP2R3A 0.10 0.05 enet 18 0.06 1.3e-05 -5.2 -6.8 1.1e-11 0.76 0.07 0.92 FALSE
23 GTEx Thyroid RP11-85F14.5 0.07 0.00 lasso 7 0.01 4.7e-02 6.5 -9.1 6.5e-20 0.54 0.12 0.14 TRUE
24 YFS Blood MSL2 0.02 0.04 lasso 2 0.03 9.9e-11 -8.2 8.2 3.1e-16 -0.96 0.03 0.97 FALSE
25 YFS Blood NCK1 0.01 0.02 enet 4 0.02 2.2e-06 6.5 -6.5 8.5e-11 0.27 0.98 0.00 FALSE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma STAG1 0.04 0.02 lasso 3 0.02 4.1e-03 -7.6 6.5 6.8e-11 -0.73 0.14 0.61 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma PCCB 0.06 0.02 lasso 2 0.03 2.3e-04 -8.6 5.8 9.1e-09 -0.74 0.02 0.95 FALSE