Best TWAS P=1.59e-08 · Best GWAS P=1.5e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CEP44 | 0.20 | 0.13 | enet | 7 | 0.15 | 6.3e-12 | -5.7 | 5.3 | 1.2e-07 | -0.97 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Colon Sigmoid | CEP44 | 0.44 | 0.43 | enet | 8 | 0.43 | 8.3e-17 | 4.7 | 5.2 | 1.6e-07 | -0.95 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Colon Transverse | CEP44 | 0.28 | 0.14 | enet | 27 | 0.19 | 3.2e-09 | -4.5 | 5.2 | 2.3e-07 | -0.83 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Esophagus Mucosa | CEP44 | 0.20 | 0.10 | lasso | 6 | 0.10 | 3.3e-07 | 4.8 | 5.2 | 2.0e-07 | -0.92 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Heart Atrial Appendage | CEP44 | 0.25 | 0.16 | lasso | 2 | 0.15 | 3.7e-07 | -5.6 | 5.4 | 5.1e-08 | -0.98 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Lung | CEP44 | 0.15 | 0.14 | enet | 5 | 0.14 | 8.6e-11 | -5.6 | 5.7 | 1.6e-08 | -1.00 | 0.00 | 1.00 | TRUE |
| 7 | ROSMAP | Brain Pre-frontal Cortex | CEP44 | 0.10 | 0.06 | lasso | 6 | 0.06 | 4.5e-08 | -5.7 | 5.4 | 6.2e-08 | -0.97 | 0.00 | 1.00 | FALSE |