TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
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Impedance of arm (right)
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chr5:41,726,855-44,208,409
Best TWAS P=9.83e-09 · Best GWAS P=5.3e-10 conditioned to 0.000341
42M
42.5M
43M
43.5M
44M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
GHR
0.14
0.02
lasso
9
0.06
9.9e-03
-5.8
5.7
9.8e-09
-0.31
0.08
0.42
TRUE
2
GTEx
Cells Transformed fibroblasts
C5orf34
0.10
0.01
enet
20
0.01
3.0e-02
-1.7
-5.6
2.5e-08
-0.04
0.05
0.16
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
SEPP1
0.18
0.19
lasso
11
0.21
1.3e-26
-5.0
5.2
2.5e-07
-0.48
0.62
0.38
TRUE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
GHR
0.12
0.11
enet
6
0.13
2.5e-13
4.7
5.5
4.0e-08
-0.26
0.19
0.81
FALSE