Best TWAS P=7.83e-14 · Best GWAS P=6.81e-15 conditioned to 2.54e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | 6.7 | 6.5 | 6.5e-11 | -0.06 | 0.71 | 0.29 | TRUE |
| 2 | YFS | Blood | MEF2C | 0.16 | 0.09 | enet | 28 | 0.12 | 5.1e-36 | 7.5 | -7.5 | 7.8e-14 | 0.09 | 0.01 | 0.99 | TRUE |