Best TWAS P=1.98e-08 · Best GWAS P=4.38e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | USP49 | 0.09 | 0.08 | lasso | 2 | 0.05 | 6.2e-05 | 5.4 | 5.5 | 3.5e-08 | 0.98 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Testis | MED20 | 0.13 | 0.03 | lasso | 6 | 0.00 | 2.0e-01 | 5.3 | -5.3 | 1.5e-07 | -0.98 | 0.02 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CCND3 | 0.04 | 0.00 | blup | 99 | 0.01 | 1.8e-03 | 5.3 | -5.4 | 6.7e-08 | -0.68 | 0.01 | 0.53 | FALSE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | MED20 | 0.09 | 0.07 | lasso | 5 | 0.07 | 3.4e-04 | 5.3 | -5.6 | 2.0e-08 | -0.98 | 0.01 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | MED20 | 0.03 | 0.05 | lasso | 2 | 0.04 | 1.2e-03 | 5.0 | -5.4 | 5.9e-08 | -0.95 | 0.01 | 0.92 | FALSE |