TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of arm (right)
:
←
→
chr6:41,073,638-42,587,818
Best TWAS P=1.98e-08 · Best GWAS P=4.38e-08 conditioned to 1
41M
41.2M
41.4M
41.6M
41.8M
42M
42.2M
42.4M
42.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
MED20
0.09
0.07
lasso
5
0.07
3.4e-04
5.3
-5.6
2.0e-08
-0.98
0.01
0.98
TRUE
1
GTEx
Lung
USP49
0.09
0.08
lasso
2
0.05
6.2e-05
5.4
5.5
3.5e-08
0.98
0.01
0.99
FALSE
5
The Cancer Genome Atlas
Stomach Adenocarcinoma
MED20
0.03
0.05
lasso
2
0.04
1.2e-03
5.0
-5.4
5.9e-08
-0.95
0.01
0.92
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
CCND3
0.04
0.00
blup
99
0.01
1.8e-03
5.3
-5.4
6.7e-08
-0.68
0.01
0.53
FALSE
2
GTEx
Testis
MED20
0.13
0.03
lasso
6
0.00
2.0e-01
5.3
-5.3
1.5e-07
-0.98
0.02
0.86
FALSE