Best TWAS P=3.64e-09 · Best GWAS P=8.36e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | SUPT3H | 0.22 | 0.12 | lasso | 6 | 0.10 | 8.1e-04 | 5.7 | 5.6 | 2.0e-08 | 0.88 | 0.05 | 0.84 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | SUPT3H | 0.38 | 0.40 | lasso | 2 | 0.34 | 1.3e-09 | 5.7 | 5.6 | 1.7e-08 | 0.84 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Brain Cortex | SUPT3H | 0.28 | 0.01 | lasso | 7 | 0.01 | 2.1e-01 | 5.8 | 5.9 | 3.6e-09 | 0.99 | 0.03 | 0.88 | TRUE |
| 4 | GTEx | Brain Nucleus accumbens basal ganglia | SUPT3H | 0.16 | 0.11 | lasso | 4 | 0.08 | 3.6e-03 | 5.5 | 5.5 | 3.8e-08 | 0.94 | 0.04 | 0.82 | FALSE |
| 5 | GTEx | Testis | SUPT3H | 0.30 | 0.16 | lasso | 7 | 0.17 | 6.7e-08 | 5.5 | 5.4 | 7.7e-08 | 0.93 | 0.03 | 0.97 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SUPT3H | 0.04 | 0.01 | blup | 191 | 0.02 | 6.5e-03 | 5.7 | 5.3 | 1.1e-07 | 0.85 | 0.07 | 0.90 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SUPT3H | 0.06 | 0.05 | lasso | 3 | 0.05 | 3.9e-06 | 5.7 | 5.7 | 1.0e-08 | 1.00 | 0.02 | 0.98 | FALSE |
| 8 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SUPT3H | 0.05 | 0.01 | blup | 191 | 0.00 | 1.4e-01 | 5.7 | 5.2 | 1.8e-07 | 0.93 | 0.03 | 0.75 | FALSE |