Best TWAS P=6.51e-08 · Best GWAS P=1.59e-06 conditioned to 0.0647
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | NT5DC1 | 0.07 | 0.03 | enet | 9 | 0.05 | 9.8e-05 | 4.8 | -5.4 | 8.1e-08 | -0.59 | 0.02 | 0.81 | FALSE |
2 | The Cancer Genome Atlas | Glioblastoma Multiforme | FRK | 0.13 | 0.01 | blup | 94 | 0.05 | 1.5e-02 | -3.7 | -5.4 | 6.5e-08 | -0.62 | 0.01 | 0.17 | TRUE |