Hub : Genes

NT5DC1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.2250	0.0720	5.1e-06	0.076	NA	0.064	NA	0.078	5.3e-05	NA	2.1e-04	NA	4.6e-05
2	GTEx	Artery Tibial	0.2060	0.0533	1.8e-10	0.066	NA	0.130	NA	0.125	6.8e-06	NA	2.5e-10	NA	5.5e-10
3	GTEx	Cells Transformed fibroblasts	0.0680	0.0320	2.3e-03	0.027	NA	0.051	NA	0.045	3.6e-03	NA	9.8e-05	NA	2.4e-04
4	GTEx	Esophagus Mucosa	0.0910	0.0360	9.7e-04	0.076	NA	0.018	NA	0.050	8.3e-06	NA	2.2e-02	NA	2.9e-04
5	GTEx	Muscle Skeletal	0.1566	0.0358	2.4e-13	0.173	NA	0.164	NA	0.173	9.7e-17	NA	7.7e-16	NA	1.1e-16
6	GTEx	Nerve Tibial	0.1571	0.0490	1.2e-05	0.125	NA	0.118	NA	0.129	3.8e-09	NA	1.1e-08	NA	2.1e-09
7	GTEx	Whole Blood	0.0880	0.0440	9.1e-04	-0.002	NA	0.016	NA	0.003	5.7e-01	NA	1.1e-02	NA	1.7e-01
8	METSIM	Adipose	0.1056	0.0284	1.3e-11	0.082	0.070	0.081	0.081	0.093	2.5e-12	1.1e-10	3.8e-12	4.2e-12	8.2e-14
9	YFS	Blood	0.0712	0.0210	8.0e-11	0.030	0.039	0.034	0.039	0.034	4.3e-10	1.2e-12	2.6e-11	6.4e-13	2.1e-11
10	TCGA	Prostate Adenocarcinoma	0.1005	0.0435	2.2e-03	0.006	0.041	0.013	NA	0.009	7.2e-02	3.8e-05	1.4e-02	NA	3.2e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	1.2	1.9	4.3	-1.0	-1.5	1.1	1.3	1.9	0.8	1.0	1.5	2.1	-0.7
Bipolar Disorder or Schizophrenia	0.6	1.4	4.8	-1.2	-1.6	1.5	0.2	0.7	-0.4	0.6	0.3	2.2	-1.1
Depressed Affect (Nagel 2018)	0.8	1.6	4.1	2.0	1.6	-1.5	-1.4	-1.4	-1.2	-0.2	-1.2	-0.5	-0.8
Depression (Nagel 2018)	0.1	0.2	0.4	0.5	-0.6	0.3	0.2	0.3	-0.4	0.6	0.4	0.3	-0.7
Intelligence (Savage-Jansen 2018)	0.8	2.5	8.9	-1.3	-1.7	1.3	1.9	1.5	0.8	3.0	1.7	1.0	0.3
Neuroticism (Nagel 2018)	0.4	0.9	1.9	0.9	0.5	-0.4	-1.4	-1.3	-1.3	0.0	-1.1	0.4	-0.8
Schizophrenia (2018)	0.4	0.7	1.4	-0.7	-0.8	1.1	-0.7	-0.6	-1.2	-0.0	-0.8	1.1	-0.9
Schizophrenia vs Biploar Disorder	0.3	0.4	1.7	-1.3	-0.1	0.5	-0.2	-0.6	-0.2	0.6	-0.6	-0.7	0.6
Worry (Nagel 2018)	0.5	1.1	2.6	-1.6	-1.1	1.4	-0.4	-0.3	-0.5	1.3	-0.1	1.6	-0.4
Alzheimer’s Disease (in mother)	0.6	0.7	2.0	1.1	0.7	-0.9	-0.6	-0.4	-0.4	-1.4	-0.5	-1.3	-0.6
Alzheimer’s Disease (in father)	0.5	0.5	1.7	-0.5	0.2	0.1	1.0	0.8	0.1	0.6	0.9	1.3	0.7
Alzheimer’s Disease (including proxy)	0.5	0.7	2.0	1.1	1.4	-1.2	-0.6	-0.5	-0.7	-0.8	-0.5	-0.6	0.1
Crohns Disease (2017)	0.1	0.2	0.4	0.3	0.6	0.1	-0.5	-0.6	-0.6	-0.3	-0.6	0.4	0.1
Irritable Bowel Disease (IBD)	0.1	0.3	1.3	0.6	0.5	0.1	-0.1	0.1	0.0	-0.9	-0.0	0.8	-1.1
Ulcerative Colitis (UC)	0.2	0.4	1.2	0.5	0.4	0.1	0.4	0.5	0.4	-1.0	0.4	0.5	-1.1
Major Depression (MDD)	1.6	1.9	3.6	-1.9	-1.3	1.6	1.7	1.1	1.8	1.2	1.5	-0.7	0.3
Reaction Time	0.1	0.1	0.6	-0.5	-0.4	-0.2	-0.3	-0.3	-0.7	-0.1	-0.2	0.0	0.1
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.1	0.5	0.2	0.2	1.5	1.0	1.2	1.2	1.2	-1.5	-0.3
Breast Cancer	0.4	0.9	3.1	0.5	0.3	-1.8	-1.0	-1.3	-0.7	-0.4	-1.3	-0.4	0.7
Ovarian Cancer	1.1	1.4	3.4	-1.9	-1.2	1.1	1.1	0.7	1.0	1.2	0.9	-0.0	1.7
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.6	0.8	2.2	-1.5	-0.4	0.7	-0.1	-0.1	-0.2	-1.3	-0.1	1.4	-1.2
Bipolar Disorder (2011)	1.4	1.4	2.1	-1.4	-1.5	1.4	1.2	1.4	0.7	-0.0	1.2	1.4	-0.5
Body Mass Index (BMI) (2010)	0.2	0.3	1.0	-0.8	-1.0	0.0	-0.5	-0.3	-0.8	0.1	-0.3	0.2	-0.4
Coronary Artery Disease (CAD)	1.0	1.1	3.0	-0.7	-0.7	0.8	1.5	0.8	0.8	1.5	0.8	-0.6	1.7
Crohns Disease (2012)	0.2	0.4	2.0	0.5	0.9	-0.1	-0.1	-0.4	-0.6	-0.1	-0.3	0.2	1.4
Mean Putamen Volume	2.4	2.8	6.0	1.8	1.6	-2.4	-1.9	-1.8	-2.0	-1.2	-1.8	-0.6	-0.2
Fasting Glucose	0.9	1.1	3.6	0.6	0.6	-1.1	-0.1	-1.0	0.0	1.3	-0.7	-1.5	1.9
HbA1C	0.9	1.0	1.4	-1.1	-0.8	0.9	1.2	1.2	0.8	0.9	1.0	0.9	1.1
HDL Cholesterol	1.1	1.9	4.0	-2.0	-2.0	1.8	0.8	1.1	0.7	1.0	1.0	1.9	-0.1
LDL Cholesterol	13.2	20.9	34.8	-4.1	-3.8	5.1	5.9	5.7	5.4	4.6	5.7	1.5	-0.1
Lupus	1.4	2.1	5.4	1.2	1.2	-2.3	-1.3	-1.7	-1.5	1.0	-1.7	-1.1	0.6
Neuroticism (2016)	0.9	1.4	2.4	-0.8	0.0	1.2	1.6	1.2	1.5	0.1	1.2	1.6	1.2
Primary Biliary Cirrhosis	0.8	1.2	3.6	1.3	1.9	-1.5	-0.9	-0.9	-0.7	-0.8	-1.0	-0.5	0.8
Rheumatoid Arthritis	0.1	0.2	0.8	-0.2	0.5	0.3	-0.6	-0.5	-0.1	0.1	-0.4	0.2	0.9
Schizophrenia (2014)	0.4	0.8	2.2	-1.5	-1.3	1.5	0.0	0.3	-0.4	0.3	-0.1	1.0	-0.7
Triglycerides	4.4	7.2	13.7	-2.7	-2.6	3.7	2.8	2.9	2.6	2.4	3.1	2.1	-1.4
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.4	-0.2	0.3	-0.5	-0.7	-0.9	-0.4	0.0	-1.1	-1.2	0.5
Ulcerative Colitis	0.9	1.3	4.3	2.0	1.1	-1.0	-0.4	0.3	0.0	-0.8	-0.1	1.1	-2.1
Blood Eosinophil Count	0.1	0.8	2.3	-1.5	-0.8	1.3	1.0	0.9	0.5	-0.4	0.9	0.7	0.1
Blood Platelet Count	0.1	1.6	5.4	0.5	0.3	-1.0	-1.3	-0.5	-1.0	-2.2	-0.9	0.4	-2.3
Blood Red Count	0.6	5.6	14.6	2.0	3.0	-2.3	-1.9	-2.9	-1.6	-1.7	-2.4	-3.8	0.4
Blood White Count	0.4	3.2	6.4	-2.5	-0.4	1.9	2.5	1.7	2.2	1.6	2.1	0.6	0.6
Heel T-Score	0.1	0.5	2.8	0.4	0.4	-0.2	0.6	0.5	0.5	0.2	0.6	-0.6	1.7
BMI	0.2	1.2	3.3	-1.4	-1.2	0.3	-1.1	-1.0	-1.8	-1.2	-1.1	0.1	-0.5
Height	3.8	74.0	136.9	11.5	7.0	-11.7	-9.7	-9.4	-6.8	-5.9	-9.6	-7.9	-2.1
Waist Hip Ratio (WHR)	0.1	0.4	2.3	-0.2	0.2	1.5	0.1	0.6	0.4	-0.9	0.3	0.4	-0.5
Systolic Blood Pressure	0.4	1.9	5.1	-1.3	0.2	1.0	1.8	1.2	2.3	1.8	1.5	0.1	1.1
Smoking Status	0.2	0.6	2.8	0.9	1.7	-0.2	-0.1	-0.2	0.2	-0.5	-0.3	0.4	1.2
Allergy or Eczema	1.4	3.7	7.9	-0.5	-0.9	2.0	2.6	2.8	2.1	0.3	2.6	2.5	-0.2
Cardiovascular Disease	3.8	12.5	19.0	-3.9	-3.3	4.2	4.3	3.7	3.1	4.4	3.8	2.4	0.0
Hypothyroidism (self reported)	0.2	0.4	1.1	0.2	0.1	-0.6	-1.0	-1.1	-0.8	-0.0	-0.8	-0.4	0.1
Respiratory disease	2.0	4.4	7.6	-2.1	-1.3	2.7	2.3	2.1	2.0	2.0	2.2	2.8	-0.7
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.3	-1.5	-1.2	0.7	0.5	0.3	0.5	0.4	0.4	-0.3	1.5
Lung FEV1/FVC ratio	3.1	15.7	25.8	3.6	5.1	-4.9	-3.7	-4.6	-2.8	-2.8	-4.5	-4.1	2.7
Lung FVC	0.1	0.5	1.5	0.6	0.9	0.1	-0.2	0.0	-0.4	1.2	-0.2	1.2	-0.5
Neuroticism	0.5	1.2	2.8	0.7	0.7	-0.6	-1.7	-1.6	-1.6	-0.6	-1.5	0.5	-0.6
Chronotype (morning person)	0.7	1.5	6.4	-0.5	0.8	0.4	1.2	0.7	1.9	1.0	0.8	-0.6	2.5
Hair Pigment	0.1	3.4	7.8	1.2	2.0	-1.7	-2.5	-2.2	-2.8	-1.2	-2.3	0.3	0.3
Tanning	0.0	0.5	1.5	0.9	0.4	0.1	0.7	0.6	0.3	-0.7	0.5	1.2	-0.5
Hand grip strength (left)	0.3	0.8	2.9	0.8	1.7	-1.2	-0.8	-0.9	0.2	-0.8	-0.7	-0.6	0.4
Number of treatments/medications taken	0.8	1.4	3.6	-1.9	-1.0	1.6	1.0	0.9	0.5	0.5	0.9	1.7	-0.8
Average weekly spirits intake	0.3	0.3	0.7	-0.1	0.4	0.5	-0.8	-0.8	-0.5	0.3	-0.9	-0.5	0.1
Sensitivity / hurt feelings	0.3	0.5	1.2	0.5	0.0	-0.6	-0.9	-1.1	-0.8	0.0	-0.9	-0.4	0.5
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.0	-0.2	-0.9	1.0	0.7	1.0	0.1	0.7	1.0	0.8	-0.6
Hearing difficulty/problems: Yes	1.0	1.5	2.2	-1.2	-1.0	1.4	1.4	1.5	1.3	1.1	1.4	1.3	-0.8
Relative age of first facial hair	0.7	1.3	3.0	1.2	0.9	-1.7	-1.3	-1.5	-1.4	-0.5	-1.4	-0.2	-0.1
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.1	-1.5	-1.8	0.6	-0.0	0.2	-0.5	1.0	0.1	1.2	-0.5
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.9	-0.6	-1.1	1.2	0.8	0.8	0.2	1.7	0.7	0.9	-0.2
Ever had hysterectomy (womb removed)	2.1	2.4	5.3	-0.3	1.7	-0.0	-2.3	-1.8	-2.3	-0.4	-2.0	1.4	0.8
Systolic blood pressure, automated reading	0.3	0.8	3.2	-0.4	0.8	0.3	0.6	0.2	1.4	1.0	0.5	-0.5	1.8
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	5.5	-1.8	-0.8	0.5	0.6	0.2	-0.1	2.0	0.4	0.7	2.4
Angina	0.5	0.7	4.2	0.4	0.4	0.0	0.6	0.1	0.7	1.1	0.3	0.0	2.0
Medication for hormone replacement therapy	0.6	0.6	2.5	-0.7	-0.1	0.8	0.8	0.9	0.7	0.4	0.8	-0.2	1.6
Vitamin and mineral supplements	1.9	2.6	6.4	0.4	-1.0	1.5	1.6	1.9	2.3	-0.4	1.9	0.7	-2.5
Supplements: Zinc	1.1	1.2	4.3	-2.1	-1.8	1.2	-0.2	0.2	-0.9	0.2	-0.0	1.3	0.5
Medication: Co-codamol	0.4	0.5	3.0	0.2	-0.7	-0.0	-0.1	0.2	0.3	1.7	0.2	0.5	-1.1
Medication: Metformin	0.4	0.5	2.5	-0.9	-1.1	0.4	-0.0	-0.3	-0.3	0.3	-0.1	-0.8	1.6
Diabetes (father)	0.4	0.5	2.3	-0.3	-0.2	-0.9	-0.3	-0.7	0.2	-0.0	-0.6	-1.5	1.1
Diabetes (mother)	0.3	0.4	1.3	-0.7	0.3	0.3	0.9	0.5	1.1	0.4	0.7	-0.0	0.0
Severe depression (siblings)	0.3	0.3	0.9	-0.6	0.0	0.3	-0.5	-0.4	-0.6	-0.9	-0.3	0.9	0.1
Pack years adult smoking proportion	1.3	1.9	4.4	2.1	1.1	-1.9	-1.5	-1.7	-1.2	-0.5	-1.6	-0.4	-0.9
Impedance of leg (right)	0.8	3.9	9.6	3.1	2.5	-2.6	-2.1	-1.8	-0.8	-1.2	-1.8	-1.7	0.5
Leg fat-free mass (left)	0.5	2.6	5.4	1.4	0.3	-2.3	-1.8	-2.0	-1.7	-1.4	-1.9	-1.4	-0.6
Trunk fat percentage	3.8	15.2	22.8	4.0	2.8	-4.7	-4.7	-4.7	-4.2	-3.4	-4.8	-3.1	0.6
Hand grip strength (right)	0.8	2.2	3.8	1.9	1.9	-1.9	-1.6	-1.6	-0.9	-1.2	-1.5	-1.2	0.1
Townsend deprivation index at recruitment	0.8	1.1	3.0	1.1	1.7	-1.1	-0.8	-1.3	-0.8	0.4	-1.1	-1.2	0.2
Current tobacco smoking	0.2	0.3	1.1	1.0	1.1	-0.5	0.2	0.2	0.5	-0.4	0.1	-0.1	0.5
Average weekly fortified wine intake	0.4	0.5	1.9	0.2	-0.3	-0.2	-0.9	-0.5	-1.1	-0.4	-0.5	0.3	-1.4
Maternal smoking around birth	0.8	1.1	2.6	1.5	1.3	-1.3	-1.0	-0.8	-0.3	-1.6	-0.9	-0.2	0.1
Fed-up feelings	0.8	1.5	4.5	2.1	1.7	-1.5	-1.2	-1.1	-0.9	-0.8	-1.1	-0.0	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	1.0	0.2	-0.0	0.2	-0.0	0.1	-0.5	0.5	0.1	0.6	-1.0
Relative age voice broke	0.3	0.4	2.5	0.1	-0.9	0.3	0.3	0.1	-0.6	-0.3	0.2	1.6	-0.4
Taking other prescription medications	1.2	1.9	3.3	-1.8	-1.7	1.8	1.4	1.4	1.2	0.8	1.4	0.6	-0.9
Age when periods started (menarche)	2.4	5.8	13.0	2.4	1.2	-1.8	-3.3	-2.8	-3.6	-1.5	-3.1	1.0	-1.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.8	0.3	0.3	0.2	-1.3	-0.9	-1.2	-0.4	-1.2	0.9	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	1.6	-0.9	-1.2	1.0	1.2	1.2	1.0	0.7	1.3	0.8	-0.1
Tinnitus: Yes, but not now, but have in the past	1.2	1.2	5.0	1.3	-0.2	-1.0	-1.1	-1.0	-0.6	-0.9	-1.0	0.5	-2.2
Qualifications: CSEs or equivalent	0.6	0.7	3.7	0.2	0.2	-0.2	-0.0	-0.8	-0.1	-0.4	-0.5	-1.9	1.6
Serious illness, injury or assault to yourself	1.8	2.1	6.0	-2.1	-2.5	1.7	1.1	1.2	1.2	0.5	1.1	1.1	-1.0
High blood pressure	1.9	5.2	8.7	-2.2	-1.9	2.7	2.8	2.4	2.4	3.0	2.5	1.6	0.3
Hayfever, allergic rhinitis or eczema	1.0	2.3	4.7	-1.1	-1.3	1.7	2.0	1.8	1.2	0.3	1.8	2.2	-0.3
Multivitamins +/- minerals	1.1	1.5	4.5	-0.6	0.5	-0.5	-1.1	-1.4	-2.1	0.3	-1.4	0.2	2.0
Stomach or abdominal pain in last month	2.1	2.6	6.2	2.5	1.9	-1.7	-2.0	-1.4	-1.4	-1.7	-1.7	-0.1	0.2
Supplements: Glucosamine	1.3	1.7	6.8	0.0	-0.8	0.6	1.0	1.5	0.5	0.5	1.3	1.9	-2.6
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	5.5	0.9	0.2	-1.1	-0.7	-0.4	-0.8	-1.4	-0.5	0.6	-2.3
Medication: Atenolol	1.2	1.6	2.5	1.3	1.3	-1.6	-1.0	-1.4	-1.1	-1.1	-1.4	-0.8	1.2
Medication: Levothyroxine sodium	0.1	0.2	1.5	-0.2	-0.6	0.3	-0.2	-0.0	0.1	-0.1	0.0	0.4	-1.2
Sitting height	2.8	20.0	50.4	5.9	3.7	-7.1	-4.1	-4.5	-1.9	-2.5	-4.3	-6.0	-0.2
Chronic bronchitis/emphysema (father)	1.6	1.8	5.2	1.7	2.3	-1.8	-1.4	-1.1	-0.9	0.4	-1.3	0.1	-1.1
High blood pressure (mother)	0.7	1.0	2.1	-0.9	-1.1	0.8	1.1	1.1	1.4	1.3	1.2	-0.1	-0.5
Body mass index (BMI)	0.1	0.6	1.3	-0.9	-0.8	0.6	-0.6	-0.4	-1.1	-1.1	-0.6	0.5	-0.6
Impedance of leg (left)	1.2	5.7	11.4	3.4	3.1	-3.0	-2.7	-2.4	-1.5	-1.5	-2.4	-1.8	0.8
Leg predicted mass (left)	0.5	2.5	5.4	1.4	0.4	-2.3	-1.8	-2.0	-1.6	-1.4	-1.9	-1.4	-0.5
Trunk fat mass	3.2	13.6	20.5	3.8	2.5	-4.5	-4.4	-4.4	-3.9	-3.4	-4.5	-3.0	0.1
Waist circumference	0.3	1.0	2.1	0.6	-0.3	-0.3	-1.3	-1.0	-1.4	-1.4	-1.3	-0.5	-0.5
Number of incorrect matches in round	0.4	0.7	2.0	1.4	1.1	-0.9	-0.7	-0.3	0.1	-0.4	-0.4	0.5	-1.2
Past tobacco smoking	0.3	0.5	4.2	0.1	-0.7	-0.0	-0.0	0.5	-0.1	-0.2	0.3	-0.2	-2.0
Alcohol usually taken with meals	0.6	1.1	1.7	-1.2	-0.7	1.2	1.1	1.3	1.0	0.1	1.3	1.1	-0.4
Nervous feelings	2.1	3.9	9.2	-2.8	-1.7	2.5	1.4	1.7	1.1	1.2	1.7	3.0	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	1.8	-0.9	-1.2	1.2	1.0	1.2	0.9	1.4	1.3	0.8	-1.1
Hearing difficulty/problems with background noise	0.7	1.2	6.2	-0.3	-0.5	0.5	0.0	0.4	-0.4	1.6	0.2	2.5	-1.4
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	-1.4	-0.6	0.2	-0.4	-0.8	-0.8	1.4	-0.5	0.4	0.2
Had menopause	0.4	0.5	1.4	0.6	0.1	-0.1	0.8	0.7	1.1	-0.3	0.7	-1.2	-0.3
Had other major operations	0.4	0.5	3.9	0.2	-0.8	-0.3	-0.5	-0.1	-0.5	-0.0	-0.3	0.3	-2.0
Forced vital capacity (FVC)	1.3	5.0	11.0	3.2	2.5	-3.3	-2.2	-2.4	-1.3	-0.2	-2.3	-2.0	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.6	-0.1	0.3	-0.1	0.4	0.4	0.5	-0.4	0.4	0.3	0.8
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.9	-0.4	0.3	0.2	0.1	-0.1	-0.2	-0.6	0.1	-0.2	1.7
Qualifications: None of the above	0.9	2.0	6.7	1.4	2.2	-1.2	-0.8	-1.2	0.1	-0.9	-1.2	-2.6	-0.1
Financial difficulties in last 2 years	0.4	0.5	3.7	0.6	-0.3	-0.5	-0.0	-0.2	-0.5	1.9	-0.2	-0.5	0.3
Mouth/teeth dental problems	2.9	4.5	8.8	-2.8	-2.0	3.0	2.4	2.3	1.8	1.3	2.4	1.8	0.0
Heart attack	0.3	0.4	1.1	-0.7	0.3	0.4	0.8	0.5	1.0	-1.0	0.6	0.0	0.2
Allergy	0.8	1.8	5.5	1.0	1.0	-1.4	-1.5	-1.5	-1.0	-0.3	-1.4	-2.4	1.1
Pain all over the body in last month	0.2	0.3	0.5	0.7	0.5	-0.1	0.6	0.6	0.7	-0.2	0.7	-0.1	0.0
Diabetes (self-reported)	0.7	1.0	5.2	-1.2	-1.4	0.5	0.4	0.1	0.1	1.0	0.2	-0.5	2.3
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	2.6	-1.5	-1.4	1.4	1.6	1.3	0.9	0.6	1.4	0.9	0.7
Medication: Ramipril	0.2	0.2	0.8	0.2	-0.8	-0.3	0.4	0.4	0.3	0.0	0.5	-0.9	0.2
Medication: Simvastatin	4.0	5.9	10.3	-2.7	-2.2	2.8	3.2	2.6	2.8	2.4	2.8	0.3	0.9
Fluid intelligence score	0.5	1.1	3.2	-0.7	-0.8	1.1	1.3	0.9	0.9	1.8	1.2	-0.7	-0.8
Illnesses of siblings	1.6	2.2	4.9	2.1	1.3	-1.6	-1.4	-1.3	-1.7	-2.2	-1.3	0.6	0.7
Neuroticism score	0.2	0.4	1.0	0.6	0.3	-0.2	-0.8	-0.8	-0.7	-0.1	-0.6	1.0	-0.5
Weight	1.2	5.7	8.6	2.2	1.0	-2.9	-2.9	-2.8	-2.5	-2.6	-2.9	-2.1	-0.8
Impedance of arm (right)	2.9	13.5	28.8	5.0	3.4	-5.4	-3.7	-4.0	-2.9	-1.4	-3.9	-3.7	1.3
Arm fat percentage (right)	0.7	2.8	4.6	1.3	0.8	-1.7	-2.0	-2.0	-2.1	-2.0	-2.1	-1.2	0.3
Trunk fat-free mass	0.1	0.7	2.2	0.6	-0.3	-1.1	-0.6	-0.5	0.0	-1.2	-0.5	-0.7	-1.5
Hip circumference	0.5	2.3	4.6	1.3	-0.3	-1.3	-1.8	-1.6	-2.1	-2.0	-1.7	-0.7	-1.2
Time employed in main current job	2.5	2.8	4.6	1.9	1.1	-2.1	-1.9	-1.8	-1.4	-2.1	-1.8	-1.6	-0.4
Alcohol intake versus 10 years previously	0.3	0.5	1.7	0.6	0.1	-0.5	-0.4	0.1	0.4	-1.3	-0.1	-0.9	-1.3
Father’s age at death	0.5	0.7	2.2	0.4	-0.6	0.8	0.3	0.7	-0.3	0.9	0.5	1.5	-1.4
Worrier / anxious feelings	0.4	0.7	1.9	-1.1	-0.8	0.7	-0.0	0.1	-0.1	1.4	0.1	1.1	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	-0.0	0.1	-0.4	-0.4	-0.7	-0.6	-0.0	-0.5	-0.2	0.5
Falls in the last year	0.7	1.0	1.8	-1.0	-1.4	1.2	0.8	0.7	1.2	1.0	1.0	-0.8	0.3
Hair/balding pattern: Pattern 3	2.5	3.7	6.7	-1.4	-1.8	2.0	1.9	2.6	2.6	2.0	2.4	0.6	-1.1
Number of live births	1.0	1.4	3.8	1.8	1.9	-0.9	-1.1	-0.9	-0.5	-1.4	-1.1	-0.5	0.4
Forced expiratory volume in 1-second (FEV1)	2.0	6.8	12.7	2.9	3.2	-3.6	-2.7	-3.1	-1.8	-0.6	-2.9	-2.8	-0.1
Pulse rate	1.0	1.7	4.2	-1.3	-1.2	1.6	1.4	1.1	1.5	2.0	1.2	0.1	-0.7
Happiness	1.2	1.5	3.1	0.6	0.8	-1.8	-1.0	-1.6	-1.0	-1.0	-1.3	-1.0	1.6
Noisy workplace	1.7	2.0	6.6	1.0	1.9	-1.2	-0.9	-1.3	-0.5	-1.5	-1.2	-1.1	2.6
Qualifications: A levels/AS levels or equivalent	1.0	2.3	7.8	-1.7	-2.8	1.4	1.3	1.5	0.8	1.1	1.5	1.3	-0.8
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	3.8	-0.8	-0.7	0.8	1.8	1.5	2.0	1.3	1.9	-0.0	-0.8
Mouth/teeth dental problems: Dentures	3.4	5.7	9.5	2.8	2.1	-2.5	-2.5	-2.3	-1.5	-3.1	-2.5	-3.0	0.5
Asthma	1.7	3.4	6.0	-1.6	-1.2	2.4	2.4	2.3	2.2	0.1	2.3	1.4	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	2.6	-0.3	-0.1	0.1	-0.2	0.0	-0.7	0.2	-0.1	1.6	-0.2
Medication: Cholesterol lowering	4.2	6.6	12.7	-2.6	-2.2	2.9	3.6	2.8	3.0	1.9	3.2	0.1	1.4
Depression (self-reported)	3.1	3.7	7.2	-1.5	-1.4	2.4	2.7	2.4	2.1	1.2	2.6	0.6	-0.8
Medication: Lansoprazole	0.1	0.1	0.2	-0.4	0.3	-0.4	0.1	-0.5	-0.1	-0.0	-0.4	-0.1	0.5
Prospective memory result	0.3	0.3	2.3	-0.2	1.5	-0.2	-0.1	0.1	-0.1	-0.8	0.0	0.5	0.3
Lung cancer (father)	0.2	0.3	1.2	-0.6	0.4	0.5	-0.0	0.1	0.3	-0.1	0.1	-0.7	1.1
Illnesses of mother	1.3	1.6	3.5	1.4	1.0	-1.1	-1.3	-1.5	-1.9	-1.3	-1.5	-0.6	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	3.4	10.9	19.4	3.4	3.7	-4.4	-3.7	-4.0	-2.5	-1.7	-3.8	-3.4	0.2
Pulse wave Arterial Stiffness index	1.1	1.2	5.3	0.2	1.9	-0.5	0.3	-0.0	1.4	0.0	0.0	-1.1	2.3
Impedance of arm (left)	4.0	18.6	35.9	5.5	4.0	-6.0	-4.4	-4.9	-3.6	-1.6	-4.7	-4.3	1.8
Arm fat mass (right)	0.9	3.9	6.2	1.8	0.7	-2.2	-2.4	-2.4	-2.4	-2.3	-2.5	-1.4	-0.3
Trunk predicted mass	0.1	0.6	2.0	0.6	-0.3	-1.1	-0.6	-0.5	0.0	-1.2	-0.5	-0.8	-1.4
Standing height	2.7	26.8	58.8	7.3	4.0	-7.7	-5.3	-5.3	-3.4	-3.5	-5.4	-5.5	-0.9
Length of working week for main job	0.4	0.5	1.4	-0.2	0.7	-0.3	-0.7	-0.9	-0.8	-1.2	-0.9	-0.1	-0.5
Exposure to tobacco smoke at home	0.3	0.3	0.9	-0.0	0.2	0.1	-0.5	-0.9	-0.9	0.3	-0.7	-0.4	0.7
Breastfed as a baby	0.9	1.1	1.7	-0.7	-0.9	1.0	1.3	1.2	1.0	0.4	1.2	1.3	-0.8
Tense / ‘highly strung’	0.9	1.5	4.4	-2.1	-0.9	1.9	0.8	1.0	1.0	0.1	1.0	0.9	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.4	-1.0	-0.8	0.8	0.9	1.1	0.9	1.1	1.2	0.5	-0.1
Hair/balding pattern: Pattern 4	1.5	3.6	8.0	-2.7	-2.4	2.8	2.1	2.0	1.2	0.1	2.0	1.2	0.2
Birth weight of first child	0.4	0.7	3.3	-0.1	0.0	0.6	-0.3	0.1	-0.1	1.2	0.0	1.8	-1.1
Peak expiratory flow (PEF)	0.5	1.3	2.0	-1.4	-0.5	1.3	1.3	1.1	1.0	1.4	1.2	0.9	0.5
Pulse wave reflection index	0.5	0.6	3.0	-0.6	1.0	0.2	0.0	0.2	0.8	-0.9	0.0	0.7	1.7
Ever highly irritable/argumentative for 2 days	0.5	0.6	4.1	0.0	0.6	-0.3	0.4	0.1	0.7	-0.4	0.3	-0.4	2.0
Loud music exposure frequency	0.7	0.8	2.2	0.9	0.7	-0.8	-0.8	-0.7	-0.7	-1.2	-0.6	0.2	-1.5
Qualifications: O levels/GCSEs or equivalent	3.1	4.9	10.3	-3.0	-3.2	2.4	2.3	2.3	2.3	1.5	2.5	0.5	-0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.6	1.2	0.5	-1.2	-0.3	-0.5	-0.5	1.2	-0.4	-0.1	-0.7
Blood clot in the leg (DVT)	1.7	2.2	4.1	0.6	1.2	-1.6	-2.0	-1.9	-1.7	-1.7	-2.0	0.0	-0.3
Medication: Paracetamol	0.5	0.9	1.4	0.8	1.0	-0.6	-1.0	-1.2	-1.0	-0.7	-1.1	-1.2	0.0
Headache pain in last month	1.0	1.7	4.6	-2.1	-1.5	1.7	1.0	0.8	0.6	1.3	1.0	1.4	0.4
Medication for cholesterol, blood pressure or diabetes	1.4	2.2	4.8	2.2	1.3	-1.8	-1.9	-1.2	-1.5	-1.0	-1.5	0.3	-1.5
Glaucoma (self-reported)	1.0	1.2	4.5	-0.3	0.8	0.6	1.0	0.3	1.1	1.7	0.5	-1.1	2.1
Gout (self-reported)	5.1	7.1	11.1	-1.5	-2.7	3.1	3.0	3.3	2.5	1.8	3.2	3.3	-0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.2	0.0	-0.4	-0.2	-1.1	-0.8	-1.0	0.0	-0.8	0.7	-0.8
Medication: Amlodipine	3.0	4.3	8.6	-1.9	-2.2	2.9	2.4	2.5	2.1	1.0	2.5	1.3	0.4
Medication: Ventolin 100micrograms inhaler	3.3	4.2	6.3	-2.3	-1.7	2.5	2.3	2.2	1.3	1.9	2.3	2.5	-0.8
Birth weight	1.0	2.2	5.3	2.1	1.5	-2.3	-1.2	-1.4	-0.7	-0.8	-1.2	-1.9	-0.8
Chronic bronchitis/emphysema (mother)	1.6	1.8	3.2	-1.1	-0.7	1.3	1.6	1.8	1.5	1.7	1.7	1.2	0.3
High blood pressure (siblings)	1.2	1.7	3.1	-1.2	-1.0	1.5	1.3	1.2	1.5	0.8	1.2	-1.8	-1.1
Forced vital capacity (FVC), Best measure	2.1	7.8	15.0	3.5	2.9	-3.9	-3.2	-3.2	-2.0	-1.4	-3.1	-2.6	-0.6
Body fat percentage	2.2	8.6	13.6	2.8	2.1	-3.3	-3.6	-3.6	-3.2	-2.8	-3.7	-2.2	0.7
Leg fat percentage (right)	0.5	1.6	3.4	0.8	0.7	-0.9	-1.8	-1.6	-1.4	-1.6	-1.7	-0.8	0.5
Arm fat-free mass (right)	0.2	1.1	2.0	0.7	0.2	-1.2	-1.3	-1.2	-1.0	-1.4	-1.3	-0.7	-0.9
Exposure to tobacco smoke outside home	0.2	0.3	1.3	0.3	-0.2	0.1	-0.0	0.2	0.7	0.8	0.2	0.2	-1.1
Comparative body size at age 10	0.6	1.6	3.9	-2.0	-1.5	1.1	-0.1	-0.4	-1.4	1.6	-0.5	1.2	1.5
Number of full brothers	0.4	0.6	1.2	-0.9	0.5	0.9	0.6	0.7	0.5	-1.0	0.6	1.1	-0.1
Worry too long after embarrassment	1.8	2.9	5.7	1.4	1.2	-1.3	-2.4	-2.4	-2.0	-1.9	-2.3	0.3	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	2.4	-0.9	-1.3	1.2	1.4	1.5	1.1	1.3	1.5	1.6	-1.4
Wheeze or whistling in the chest in last year	0.4	0.8	2.0	-1.1	-0.8	1.0	0.1	0.2	0.1	1.0	0.1	1.4	-1.3
Number of children fathered	0.8	0.9	1.8	1.3	0.2	-1.4	-1.1	-1.0	-0.9	0.1	-1.1	-0.8	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.2	-0.7	-1.4	0.0	-1.0	-0.5	-1.1	0.0	-0.6	0.7	-1.5
Age at first live birth	0.3	0.6	3.3	-0.3	-1.0	-0.2	-0.5	-0.5	-0.7	0.4	-0.4	0.6	-1.8
Pulse wave peak to peak time	1.2	1.4	5.7	0.6	-1.4	-0.4	-0.9	-0.6	-1.8	-0.4	-0.6	0.4	-2.4
Health satisfaction	0.2	0.2	0.9	-0.1	-0.5	0.6	-0.1	0.0	-0.0	-0.2	0.1	0.8	-0.9
Shortness of breath walking on level ground	0.3	0.4	1.0	-0.6	-0.6	0.8	-0.3	-0.3	-1.0	0.6	-0.3	0.8	0.5
Qualifications: College or University degree	1.3	4.1	8.8	-2.7	-2.7	2.2	1.7	2.0	1.1	1.2	1.9	3.0	0.3
Eye problems/disorders: None of the above	1.2	1.4	4.0	0.3	0.1	-1.0	-1.3	-1.1	-1.3	-2.0	-1.3	0.1	-1.6
Mouth/teeth dental problems: Loose teeth	1.0	1.2	6.5	2.5	1.4	-1.5	-0.3	-0.6	-0.6	-0.0	-0.6	0.4	0.0
Emphysema/chronic bronchitis	2.7	3.1	8.4	-2.6	-2.2	1.6	0.3	0.6	-0.6	2.7	0.6	2.9	-0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.3	0.1	-1.0	0.3	-0.4	0.1	-0.2	0.4	-0.1	0.5	-1.1
Neck or shoulder pain in last month	2.2	3.2	9.2	-2.4	-3.0	1.7	0.7	1.3	-0.3	1.1	1.1	3.0	-0.5
Medication: Blood pressure	0.4	0.6	2.8	-0.8	-0.3	0.6	0.8	0.3	0.6	0.6	0.5	-1.0	1.7
Angina (self-reported)	0.5	0.7	4.4	0.5	0.4	0.1	0.6	0.1	0.6	1.0	0.4	0.2	2.1
Migraine (self-reported)	0.2	0.3	0.8	-0.4	-0.3	-0.0	-0.8	-0.9	-0.3	0.2	-0.8	-0.2	0.7
Medication: Ibuprofen	0.7	0.9	5.5	-0.4	-0.5	0.2	-0.2	0.2	-0.8	0.7	-0.0	2.3	-1.1
Medication: Allopurinol	2.7	3.6	9.3	-0.7	-1.8	2.4	2.1	2.3	1.3	0.8	2.3	3.1	-0.6
Medication: Omeprazole	1.1	1.3	5.3	1.3	2.3	-1.2	-0.4	-0.8	-0.6	-1.4	-0.7	-0.8	0.7
Medication: Seretide 50 evohaler	0.9	1.0	2.1	-0.3	-0.8	-0.9	-1.1	-1.0	-1.4	0.8	-1.1	1.5	-0.5
Mean time to correctly identify matches	0.8	1.5	3.5	0.4	0.3	-1.4	-1.5	-1.6	-1.9	-1.0	-1.5	-0.5	0.6
Heart disease (mother)	0.3	0.4	1.3	-0.2	0.6	-0.4	0.1	-0.2	-0.0	1.1	0.0	0.6	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	3.6	-0.2	-0.7	1.1	1.4	1.9	1.9	0.1	1.6	0.3	-1.0
Whole body fat mass	2.0	8.2	13.0	2.7	1.7	-3.3	-3.5	-3.5	-3.2	-2.9	-3.6	-2.1	-0.0
Leg fat mass (right)	1.0	3.7	6.5	1.5	0.9	-1.9	-2.5	-2.4	-2.3	-2.1	-2.5	-1.1	0.3
Arm predicted mass (right)	0.3	1.4	2.4	0.8	0.2	-1.3	-1.4	-1.3	-1.0	-1.6	-1.4	-0.9	-1.2
Pulse rate, automated reading	0.3	0.9	3.6	-1.0	-0.1	1.2	0.8	0.7	1.1	1.9	0.8	0.6	-0.4
Alcohol intake frequency.	0.1	0.2	1.5	0.0	0.5	-0.2	-0.3	-0.4	-0.3	0.1	-0.3	-1.2	0.4
Comparative height size at age 10	2.0	11.1	26.8	5.2	2.6	-4.4	-2.9	-2.9	-2.0	-2.5	-2.9	-4.6	-0.7
Number of full sisters	3.6	4.3	11.2	-3.3	-2.8	2.7	1.3	1.3	0.7	3.1	1.3	1.4	-0.1
Suffer from ‘nerves’	0.2	0.4	1.5	-0.8	-0.3	1.2	0.3	0.2	0.2	-0.3	0.4	0.9	-0.2
Overall health rating	1.3	2.8	7.5	-1.6	-2.4	1.9	1.0	1.5	0.4	1.3	1.4	2.7	-1.0
Chest pain or discomfort	4.4	6.4	10.4	-2.2	-2.5	2.9	2.9	2.8	2.9	3.2	2.9	0.6	-0.5
Had major operations	1.1	1.3	4.0	2.0	-0.9	-1.4	-0.9	-1.0	-1.3	0.1	-0.9	-0.4	-1.3
Age at last live birth	0.8	1.1	4.2	1.5	0.4	-1.1	-1.1	-0.8	-0.8	-0.8	-0.6	0.1	-2.0
Family relationship satisfaction	0.4	0.5	1.1	0.5	0.3	-0.9	-0.5	-0.9	-1.1	0.8	-0.8	0.2	-0.3
Leg pain on walking	1.8	2.3	5.7	-1.1	-1.3	2.0	1.5	1.6	0.7	1.2	1.7	2.4	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.3	-1.1	0.2	0.2	0.4	0.1	0.7	-0.1	0.3	-0.6	1.0
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.7	1.3	0.7	-1.1	-0.8	-0.9	-0.9	-1.1	-0.9	-0.8	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.8	-0.9	-0.0	0.7	0.4	0.4	0.1	-0.5	0.4	-0.6	0.2
Medication: Aspirin	0.2	0.3	1.1	-0.8	-0.3	0.2	0.4	-0.0	0.4	0.8	0.2	-0.4	1.0
Supplements: Vitamin C	3.1	3.6	5.9	0.8	1.5	-2.3	-2.2	-2.4	-2.0	-1.3	-2.4	-1.3	2.0
Knee pain experienced in last month	0.9	1.4	5.7	1.4	-0.2	-1.3	-1.0	-0.6	-1.5	-0.7	-0.8	0.3	-2.4
Hypertension (Self-reported)	1.7	4.8	8.6	-1.9	-1.5	2.5	2.7	2.3	2.4	2.9	2.4	1.5	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.9	4.6	7.8	2.1	2.2	-2.8	-2.3	-2.5	-2.5	-2.0	-2.5	-0.4	-0.5
Illnesses of father: Heart disease	0.8	1.1	4.8	-2.2	-1.7	0.9	0.3	-0.1	-0.3	0.9	0.2	0.6	1.1
Illnesses of siblings: Diabetes	1.6	1.9	6.7	-2.6	-1.1	0.8	1.4	0.5	1.4	2.0	0.8	-0.7	1.3
Smoking status: Previous	0.2	0.3	2.3	-0.0	0.5	0.0	-0.1	-0.7	-0.3	0.3	-0.5	0.2	1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.2	8.3	2.3	1.0	-2.9	-1.9	-2.1	-1.3	-0.5	-2.0	-1.8	-0.3
Whole body fat-free mass	0.2	1.1	2.4	0.9	-0.1	-1.5	-1.1	-1.1	-0.8	-1.3	-1.1	-0.8	-1.2
Leg fat-free mass (right)	0.5	2.7	5.3	1.4	0.4	-2.3	-1.9	-2.0	-1.8	-1.5	-2.0	-1.3	-0.5
Arm fat percentage (left)	1.0	4.1	6.7	1.7	1.1	-2.1	-2.4	-2.5	-2.5	-2.0	-2.6	-1.6	0.6
Average weekly red wine intake	4.9	7.2	11.0	-3.0	-2.8	2.9	3.2	3.2	2.5	2.4	3.3	1.6	0.6
Handedness (chirality/laterality): Left-handed	0.9	1.0	3.5	0.7	1.3	-1.2	-0.6	-0.4	0.2	-1.9	-0.4	-0.4	-1.5
Mood swings	0.2	0.3	1.3	1.1	0.9	-0.6	-0.3	-0.4	-0.1	-0.5	-0.2	-0.6	-0.2
Loneliness, isolation	0.3	0.4	1.3	0.4	1.2	-0.1	0.5	0.5	0.5	1.0	0.6	0.7	0.4
Long-standing illness, disability or infirmity	1.0	1.6	4.7	-2.2	-1.6	1.8	0.7	0.7	0.2	1.6	0.8	0.9	0.4
Ever had bowel cancer screening	0.3	0.4	2.1	-0.5	0.7	0.6	0.2	0.3	0.6	0.0	0.2	0.5	1.5
Diabetes diagnosed by doctor	0.7	1.2	7.1	-1.2	-1.4	0.5	0.2	-0.1	0.0	0.9	-0.1	-0.6	2.7
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.0	1.0	0.7	-0.3	0.2	0.1	0.7	-0.9	0.2	-1.0	-0.1
Friendships satisfaction	1.4	1.7	2.6	-1.2	-1.2	1.5	1.3	1.5	1.3	1.6	1.5	1.0	-0.7
Qualifications: nursing, teaching	0.8	1.3	2.7	-1.0	-1.6	1.3	1.1	1.4	0.6	0.1	1.3	1.6	-0.2
Commuting to job workplace: Walk	2.9	3.1	5.6	-1.8	-1.6	2.3	1.6	1.9	1.4	2.4	1.8	0.8	-1.7
Eye problems/disorders: Cataract	0.8	1.0	2.5	-0.1	-0.6	0.6	1.2	1.4	1.6	0.6	1.5	0.1	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.1	-0.4	0.5	-0.7	-1.0	-0.9	-0.6	0.2	-1.0	-0.4	0.9
Medication for cholesterol	2.6	4.0	6.5	2.2	1.3	-2.2	-2.6	-2.5	-2.3	-1.2	-2.4	-1.2	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.2	0.6	0.4	0.4	1.0	0.7	1.0	-0.1	0.8	0.1	-1.1
Back pain experienced in last month	0.6	0.9	3.0	-1.4	-1.7	0.9	-0.7	-0.1	-1.1	0.1	-0.4	0.9	-0.7
Mineral and other dietary supplements	1.0	1.3	5.7	0.3	0.8	-0.6	-0.7	-1.3	-0.2	-0.8	-1.0	-2.4	1.5
Breast cancer (self-reported)	2.9	3.5	7.7	-1.8	-1.5	1.9	2.2	2.5	2.8	1.1	2.3	0.6	0.2
Asthma (self-reported)	1.5	3.0	5.3	-1.5	-1.2	2.3	2.2	2.1	2.1	0.2	2.1	1.6	-0.8
Osteoporosis (self-reported)	0.4	0.5	1.3	0.2	0.3	-1.1	-1.1	-0.8	-0.6	0.6	-0.9	0.3	-0.2
Osteoarthritis (self-reported)	0.9	1.2	3.2	-0.5	-1.4	0.7	0.4	1.0	-0.0	1.1	0.6	1.7	-1.8
Medication: Aspirin	0.5	0.7	1.9	-1.4	-0.9	0.8	0.7	0.5	0.5	1.0	0.6	0.3	0.9
Medication: Gliclazide	0.2	0.2	0.7	0.6	-0.2	-0.8	-0.4	-0.5	-0.2	0.5	-0.4	-0.2	0.4
Illnesses of father: None of the above (group 1)	0.3	0.4	1.4	1.0	0.3	-0.2	-0.0	0.2	0.1	-1.2	0.1	-0.4	0.9
Smoking status: Current	0.1	0.2	0.9	0.8	0.9	-0.2	0.1	0.3	0.6	-0.2	0.1	-0.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.1	6.8	-0.0	1.8	-1.9	-2.1	-2.6	-1.7	-0.6	-2.3	-2.0	1.0
Whole body water mass	0.2	1.1	2.2	0.9	-0.1	-1.5	-1.1	-1.1	-0.7	-1.2	-1.1	-0.8	-1.2
Leg predicted mass (right)	0.6	3.0	6.0	1.5	0.5	-2.5	-2.0	-2.2	-1.9	-1.5	-2.2	-1.4	-0.5
Arm fat mass (left)	1.0	4.1	6.7	1.8	0.9	-2.3	-2.5	-2.5	-2.4	-2.1	-2.6	-1.7	-0.2
Number of self-reported non-cancer illnesses	2.4	4.1	8.7	-2.3	-2.4	2.3	1.7	2.0	1.3	1.7	1.9	2.9	-1.2
Average weekly champagne plus white wine intake	0.9	1.2	3.2	0.2	0.5	-0.6	-1.8	-1.3	-1.5	-0.9	-1.5	1.1	-0.3
Miserableness	0.4	0.7	3.3	1.6	0.5	-0.2	0.1	0.2	0.3	-0.3	0.4	-0.1	-1.8
Guilty feelings	0.5	0.7	3.0	1.0	-0.4	0.2	0.0	0.5	-0.1	-0.8	0.3	1.5	-1.7
Wears glasses or contact lenses	2.4	2.8	5.7	2.2	2.0	-2.4	-1.5	-1.9	-1.1	-0.5	-1.6	-1.3	1.2
Ever taken oral contraceptive pill	0.7	0.8	1.9	-0.3	-0.8	0.8	0.9	0.7	0.5	1.4	0.8	-0.8	1.3
Hearing aid user	0.3	0.3	1.8	0.1	1.3	-0.1	0.3	0.0	0.7	-0.2	0.1	0.2	0.6
Mother’s age at death	0.3	0.3	1.2	-0.8	0.2	0.2	0.4	0.3	0.5	1.1	0.3	0.8	0.1
Financial situation satisfaction	0.3	0.4	0.9	0.0	0.8	-0.0	0.9	0.5	0.8	0.4	0.7	-0.7	0.3
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.8	0.5	-0.3	-0.8	-0.9	-0.8	-0.8	-0.6	-0.8	-0.3	0.3
Commuting to job workplace: Public transport	0.1	0.1	0.3	-0.1	-0.2	-0.0	-0.1	-0.0	0.1	0.5	-0.1	0.4	0.3
Eye problems/disorders: Glaucoma	0.7	0.8	5.3	-0.2	1.0	0.4	0.3	-0.1	0.5	0.9	0.1	-0.6	2.3
Medication: Blood pressure	0.6	1.1	2.2	-0.7	-1.5	0.9	1.1	1.0	0.7	1.1	1.0	1.4	-0.8
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.7	-1.1	-1.2	1.1	0.7	0.9	0.1	1.3	0.6	1.3	-0.0
Supplements: Fish oil (including cod liver oil)	0.5	0.7	3.1	0.4	0.3	-0.4	-0.9	-0.5	-1.1	0.7	-0.7	1.7	-0.4
High cholesterol (Self-reported)	5.7	10.0	15.8	-3.3	-3.3	4.0	3.9	3.8	3.4	1.7	3.8	2.0	-0.3
Medication: Bendroflumethiazide	0.3	0.4	1.4	-1.2	-0.9	0.9	0.4	0.1	-0.2	0.3	0.2	0.4	-0.8
Medication: Paracetamol	0.3	0.4	0.8	0.9	0.8	-0.4	-0.5	-0.5	-0.6	-0.9	-0.5	-0.2	-0.8
Medication: Lisinopril	0.5	0.6	2.7	-0.7	0.1	0.7	0.6	0.3	0.4	1.6	0.2	1.2	-0.6
Medication: Atorvastatin	2.1	2.6	10.3	-2.0	-0.1	1.3	1.9	0.9	1.6	0.6	1.3	-1.0	3.2
Illnesses of father: High blood pressure	0.5	0.7	3.4	-1.9	-1.1	0.7	0.1	-0.1	0.1	1.1	-0.1	-0.2	-0.3
Alcohol drinker status: Never	0.5	0.6	1.7	-0.6	-0.2	-0.8	-1.1	-0.9	-1.3	0.3	-1.0	-0.4	-0.5
Ever smoked	0.3	0.6	3.8	-0.7	0.4	0.1	0.2	-0.2	0.3	0.2	-0.1	0.9	2.0
Basal metabolic rate	0.4	2.0	3.7	1.2	0.3	-1.9	-1.6	-1.6	-1.2	-1.6	-1.6	-1.2	-1.0
Leg fat percentage (left)	0.6	2.1	4.2	0.8	0.9	-1.1	-2.0	-1.8	-1.7	-1.7	-2.0	-0.9	0.5
Arm fat-free mass (left)	0.1	0.6	1.7	0.4	-0.3	-0.8	-0.7	-0.6	-0.3	-1.3	-0.7	-0.7	-1.2
Number of operations (self-reported)	0.5	0.7	1.9	0.4	-1.1	-0.2	-0.7	-0.5	-1.3	-1.0	-0.5	0.1	-1.4
Average weekly beer plus cider intake	0.5	0.7	2.3	1.3	1.0	-0.8	-0.4	-0.7	0.0	-1.5	-0.6	-0.7	0.1
Irritability	1.9	3.3	6.2	2.0	1.3	-2.5	-2.2	-2.3	-1.6	-1.6	-2.1	-1.0	-0.1
Risk taking	2.0	2.9	14.4	3.8	0.4	-1.7	-1.4	-0.9	-1.1	-1.6	-1.1	-0.2	-1.8
Ever had prostate specific antigen (PSA) test	0.7	0.8	6.9	0.9	-0.1	-0.3	-0.0	0.3	0.5	-0.6	0.2	0.1	-2.6
Fractured/broken bones in last 5 years	1.4	1.8	5.7	2.4	0.9	-2.1	-1.0	-1.2	-0.3	-0.8	-1.0	-1.6	-0.6
Age started oral contraceptive pill	1.5	1.8	5.0	-1.9	-2.2	1.0	0.4	0.5	-0.8	1.7	0.4	2.1	0.1
Diastolic blood pressure, automated reading	3.3	10.2	22.1	-4.6	-1.9	4.7	3.3	3.2	3.3	2.3	3.4	2.6	0.0
Ever depressed for a whole week	0.3	0.4	1.8	-0.8	-0.8	0.9	-0.3	-0.2	-0.0	-1.3	-0.1	-0.3	-0.1
Unable to work because of sickness or disability	0.7	1.0	2.2	-0.3	-0.5	1.1	1.3	1.3	1.5	0.2	1.5	-0.4	0.5
Commuting to job workplace: Cycle	0.7	0.8	1.6	-1.3	-1.1	1.0	0.9	0.9	1.2	0.9	0.7	0.5	-0.3
Myopia	5.9	8.6	15.1	2.4	3.1	-3.9	-2.4	-3.7	-2.6	-0.9	-3.1	-2.9	3.0
Vascular/heart problems diagnosed by doctor	1.9	5.1	8.2	2.1	1.5	-2.7	-2.9	-2.3	-2.6	-2.9	-2.5	-1.2	-0.6
Cholesterol lowering medication	0.9	1.3	3.6	-1.6	0.1	0.9	1.4	0.8	1.3	0.9	1.0	-0.1	1.9
Medication: Omeprazole (e.g. Zanprol)	2.4	3.0	8.9	1.4	3.0	-1.9	-0.9	-1.6	-1.2	-2.3	-1.5	-1.2	1.3
Pain experienced in last month	1.7	2.8	9.0	1.7	2.5	-1.5	-0.4	-1.2	0.7	-1.0	-0.9	-3.0	2.0
Supplements: Calcium	0.4	0.5	2.0	-1.4	-1.2	0.6	0.3	0.4	0.1	-0.6	0.3	-0.2	-0.2
Basal cell carcinoma (self-reported)	0.4	0.5	1.2	-0.7	-0.5	1.0	0.4	-0.1	0.1	1.1	0.0	1.0	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	-0.8	0.3	0.4	0.6	0.3	0.9	-0.9	0.4	-0.0	0.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	2.0	0.3	1.0	-1.1	-1.4	-1.2	-1.2	-1.3	-1.4	0.3	-0.3
Heart disease (siblings)	1.7	2.0	5.2	-2.3	-0.8	1.4	1.8	1.1	1.3	1.7	1.4	0.5	1.2
Alcohol drinker status: Previous	0.6	0.7	3.4	0.2	-0.2	-0.2	-0.4	-0.7	-1.0	1.2	-0.5	0.5	1.8
Pack years of smoking	1.2	1.7	3.3	1.8	0.9	-1.7	-1.4	-1.6	-1.2	-0.5	-1.5	-0.5	-0.9
Impedance of whole body	2.7	14.0	26.0	4.9	3.9	-5.1	-3.9	-4.1	-2.9	-1.6	-3.9	-3.7	1.7
Leg fat mass (left)	1.0	4.0	7.0	1.6	1.1	-2.1	-2.6	-2.5	-2.4	-2.2	-2.6	-1.2	0.3
Arm predicted mass (left)	0.2	0.9	2.2	0.6	0.1	-1.0	-1.1	-0.9	-0.6	-1.5	-1.0	-0.8	-1.3