TWAS hub - FRK

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0610	0.0250	3.9e-04	0.057	0.029	0.035	0.032	0.052	1.6e-07	1.8e-04	3.3e-05	8.5e-05	6.1e-07
2	GTEx	Artery Tibial	0.1608	0.0481	9.1e-08	0.098	NA	0.121	NA	0.133	4.1e-08	NA	9.8e-10	NA	1.4e-10
3	GTEx	Cells EBV-transformed lymphocytes	0.1150	0.0440	8.9e-04	0.070	NA	0.088	NA	0.083	2.7e-03	NA	8.1e-04	NA	1.2e-03
4	GTEx	Cells Transformed fibroblasts	0.1220	0.0360	4.7e-08	0.175	NA	0.148	NA	0.157	4.1e-13	NA	3.4e-11	NA	8.0e-12
5	GTEx	Colon Transverse	0.1350	0.0490	1.2e-04	0.160	NA	0.094	NA	0.135	4.7e-08	NA	3.3e-05	NA	5.7e-07
6	GTEx	Muscle Skeletal	0.1029	0.0362	8.3e-06	0.050	NA	0.084	NA	0.055	1.0e-05	NA	1.4e-08	NA	4.0e-06
7	GTEx	Pancreas	0.0940	0.0430	6.7e-03	0.128	NA	0.068	NA	0.091	4.8e-06	NA	7.9e-04	NA	1.2e-04
8	GTEx	Stomach	0.1160	0.0510	2.1e-03	0.022	NA	0.031	NA	0.036	3.0e-02	NA	1.3e-02	NA	7.9e-03
9	GTEx	Thyroid	0.0810	0.0300	2.4e-04	0.096	NA	0.049	NA	0.085	8.4e-08	NA	1.2e-04	NA	4.6e-07
10	METSIM	Adipose	0.1467	0.0346	1.7e-13	0.097	0.121	0.099	0.122	0.101	2.7e-14	1.2e-17	1.4e-14	7.9e-18	7.4e-15
11	TCGA	Colon Adenocarcinoma	0.0960	0.0460	8.5e-05	0.100	0.064	0.093	NA	0.094	2.3e-06	1.4e-04	5.1e-06	NA	4.2e-06
12	TCGA	Glioblastoma Multiforme	0.1270	0.0760	8.2e-03	0.013	0.047	0.024	NA	0.011	1.3e-01	1.5e-02	6.3e-02	NA	1.5e-01
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0838	0.0475	2.0e-03	0.014	0.007	-0.002	NA	0.002	8.9e-03	4.8e-02	8.1e-01	NA	1.9e-01
14	TCGA	Brain Lower Grade Glioma	0.1298	0.0607	2.2e-04	0.037	0.033	0.039	NA	0.052	3.9e-05	1.1e-04	2.6e-05	NA	1.3e-06
15	TCGA	Prostate Adenocarcinoma	0.1010	0.0418	6.7e-07	0.075	0.052	0.040	NA	0.053	2.6e-08	4.0e-06	5.1e-05	NA	3.2e-06
16	TCGA	Stomach Adenocarcinoma	0.0330	0.0190	4.9e-03	0.003	0.027	0.016	NA	0.007	1.9e-01	4.6e-03	2.4e-02	NA	9.7e-02
17	TCGA	Thyroid Carcinoma	0.0760	0.0330	1.6e-06	0.093	0.071	0.077	NA	0.089	2.4e-09	2.0e-07	6.2e-08	NA	5.0e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
LDL Cholesterol	15.8	25.1	35.8	-2.9	-4.5	5.4	6.0	5.7	4.3	5.9	3.9	5.9	3.6	5.4	4.8	4.5	3.0	5.9	5.7	5.9
High cholesterol (Self-reported)	6.6	11.7	18.9	-2.5	-3.1	3.9	3.8	3.9	3.8	3.8	2.0	3.8	3.3	3.8	4.3	1.6	1.0	3.8	4.0	3.7
Medication: Cholesterol lowering	5.9	9.1	22.8	-0.8	-2.5	2.8	3.5	3.3	4.8	3.5	1.4	3.5	3.5	3.3	3.5	0.9	-0.1	3.5	2.6	3.5
Average weekly red wine intake	5.6	8.3	12.5	-2.5	-2.9	3.5	3.2	3.2	2.1	3.3	1.4	3.1	3.1	3.2	3.1	2.3	0.1	3.2	3.2	3.3
Gout (self-reported)	5.4	7.4	13.9	-3.0	-1.6	3.7	3.0	3.3	2.4	3.0	1.8	3.0	1.6	3.4	3.3	1.8	0.6	3.0	2.5	3.0
Medication: Simvastatin	5.0	7.4	13.3	-0.4	-2.6	2.5	3.1	3.0	3.7	3.2	1.9	3.2	2.8	2.9	3.2	1.1	0.9	3.2	2.8	3.2
Triglycerides	4.8	7.9	12.9	-2.2	-3.4	3.3	2.9	3.1	3.6	3.0	1.9	2.7	2.3	2.7	2.9	2.4	1.0	3.0	3.1	3.1
Cardiovascular Disease	4.7	15.6	22.9	-2.5	-4.2	4.2	4.3	4.0	4.0	4.2	3.7	4.2	4.8	4.0	3.9	3.8	0.6	4.3	4.4	4.1
Myopia	4.7	6.8	14.1	3.2	1.6	-3.8	-2.6	-3.2	-0.3	-2.4	-2.4	-2.6	-1.7	-3.1	-3.2	-1.4	-2.8	-2.5	-3.0	-2.4
Trunk fat percentage	4.4	17.7	24.7	2.4	3.4	-4.5	-4.8	-4.7	-4.2	-4.8	-3.8	-4.7	-3.8	-4.8	-4.3	-3.8	-1.8	-4.8	-5.0	-4.7
Chest pain or discomfort	4.4	6.3	9.4	-1.5	-2.2	2.9	2.9	3.0	1.2	2.8	1.9	2.9	3.1	2.9	2.5	1.7	1.7	2.9	2.4	2.8
Height	4.3	83.6	123.2	8.2	9.8	-11.1	-9.9	-9.5	-9.2	-9.7	-7.0	-9.4	-7.4	-9.9	-10.9	-8.3	1.0	-9.7	-10.1	-9.7
Depression (self-reported)	4.1	4.9	8.7	-1.9	-1.6	2.5	2.6	2.7	2.0	2.6	0.8	2.7	1.8	3.0	2.5	1.3	0.1	2.6	2.0	2.6
Medication: Ventolin 100micrograms inhaler	4.1	5.2	10.8	-2.5	-2.0	2.5	2.3	2.3	1.8	2.2	2.1	2.2	3.3	2.5	2.7	1.7	-1.2	2.3	2.4	2.2
Impedance of arm (left)	4.0	18.5	39.2	4.1	4.5	-5.6	-4.6	-4.8	-2.6	-4.5	-3.7	-4.5	-2.6	-5.1	-6.3	-1.7	-0.4	-4.4	-5.1	-4.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.0	4.7	6.8	0.8	2.0	-2.4	-2.4	-2.3	-1.7	-2.4	-2.6	-2.4	-2.4	-2.4	-2.4	-0.6	-1.5	-2.3	-2.4	-2.5
Trunk fat mass	3.7	15.9	21.6	2.5	3.2	-4.3	-4.5	-4.4	-4.1	-4.5	-3.4	-4.4	-3.6	-4.5	-4.0	-3.9	-1.4	-4.5	-4.7	-4.4
Forced expiratory volume in 1-second (FEV1), Best measure	3.7	11.9	20.1	4.5	2.8	-4.3	-3.6	-4.0	-3.1	-3.6	-1.3	-3.5	-3.0	-3.9	-4.4	-2.4	1.0	-3.7	-3.5	-3.6
Medication: Amlodipine	3.7	5.2	8.3	-1.8	-2.3	2.9	2.5	2.4	2.0	2.4	1.4	2.4	2.6	2.5	2.7	0.8	1.5	2.4	2.9	2.3
Mouth/teeth dental problems: Dentures	3.6	6.0	8.5	2.5	2.3	-2.7	-2.5	-2.5	-1.9	-2.5	-2.5	-2.4	-2.4	-2.9	-2.8	-2.4	1.0	-2.5	-2.9	-2.5
Diastolic blood pressure, automated reading	3.5	11.0	25.7	-1.6	-3.9	3.8	3.5	3.2	2.4	3.3	5.1	3.4	2.6	3.6	4.2	0.5	1.4	3.3	4.0	3.3
Supplements: Vitamin C	3.4	4.1	6.7	2.3	1.1	-2.5	-2.3	-2.5	-0.9	-2.2	0.1	-2.2	-2.3	-2.6	-2.0	-2.0	-0.4	-2.3	-1.8	-2.3
Mouth/teeth dental problems	3.2	4.9	11.5	-2.0	-2.4	2.5	2.4	2.3	1.7	2.4	1.6	2.4	1.3	2.8	3.4	0.0	-0.4	2.4	2.9	2.2
Medication for cholesterol	3.2	4.9	7.0	1.1	1.7	-2.4	-2.6	-2.5	-1.3	-2.5	-2.3	-2.6	-2.4	-2.5	-2.2	-1.3	-1.8	-2.6	-2.5	-2.5
Breast cancer (self-reported)	3.2	3.9	6.2	-0.7	-1.1	2.3	2.2	2.3	1.1	2.2	2.1	2.5	1.6	2.3	2.5	-0.1	1.8	2.2	2.3	2.2
Lung FEV1/FVC ratio	3.1	16.0	34.7	5.9	3.1	-5.4	-3.9	-4.4	-3.1	-3.8	-2.1	-3.6	-4.6	-4.8	-5.2	-1.8	0.4	-3.8	-4.4	-3.7
Time employed in main current job	3.1	3.6	7.5	1.2	2.1	-2.2	-2.0	-1.8	-1.3	-1.9	-2.7	-1.9	-1.3	-1.9	-1.4	-2.4	-1.3	-2.0	-2.3	-1.8
Qualifications: O levels/GCSEs or equivalent	3.1	4.9	9.7	-1.1	-3.1	2.6	2.5	2.4	2.0	2.4	1.5	2.4	1.5	2.6	3.1	0.8	0.5	2.4	2.5	2.4
Stomach or abdominal pain in last month	3.0	3.7	7.3	0.1	2.7	-1.7	-2.0	-1.7	-2.6	-2.0	-2.6	-1.9	-2.0	-1.7	-2.0	-1.4	-0.1	-2.0	-2.2	-2.0
Commuting to job workplace: Walk	3.0	3.2	10.0	-1.3	-2.1	1.8	1.8	1.8	1.5	1.6	1.5	1.5	1.4	1.6	1.3	3.2	1.3	1.7	2.5	1.6
Age when periods started (menarche)	2.9	7.1	12.6	-0.4	2.1	-2.3	-3.3	-3.1	-0.7	-3.4	-0.9	-3.5	-3.5	-3.0	-2.1	-1.6	-2.5	-3.3	-2.6	-3.4
Medication: Allopurinol	2.9	3.8	7.6	-2.7	-0.9	2.7	2.1	2.3	2.0	2.1	0.8	2.0	0.6	2.5	2.5	1.0	-0.9	2.1	1.4	2.2
Impedance of arm (right)	2.8	13.1	29.2	3.5	3.9	-4.8	-3.8	-4.0	-2.1	-3.8	-3.1	-3.7	-2.4	-4.3	-5.4	-1.2	0.1	-3.7	-4.1	-3.8
Standing height	2.8	27.9	44.2	5.5	6.0	-6.7	-5.5	-5.3	-4.5	-5.4	-4.8	-5.2	-4.3	-5.5	-6.6	-4.8	1.0	-5.2	-5.9	-5.3
Impedance of whole body	2.8	14.0	30.9	3.6	4.1	-4.9	-4.0	-4.1	-1.9	-3.9	-3.0	-3.9	-2.9	-4.4	-5.6	-1.3	0.3	-3.9	-4.2	-3.9
Mean Putamen Volume	2.7	3.1	6.0	0.1	2.1	-1.6	-2.1	-1.9	-1.2	-2.0	-1.5	-2.0	-1.9	-1.7	-1.7	-1.6	-0.8	-1.9	-2.5	-2.0
Sitting height	2.7	19.4	44.9	6.7	4.9	-6.1	-4.2	-4.3	-3.3	-4.1	-2.6	-3.8	-2.7	-4.6	-5.6	-5.0	1.7	-4.0	-4.5	-4.0
Body fat percentage	2.7	10.5	14.1	1.6	2.5	-3.3	-3.7	-3.7	-3.2	-3.7	-2.6	-3.6	-3.1	-3.7	-3.1	-3.2	-1.2	-3.7	-3.8	-3.7
Hair/balding pattern: Pattern 3	2.5	3.7	6.6	-1.2	-1.1	2.2	2.1	2.2	0.0	2.0	2.3	2.1	1.6	2.2	2.2	0.7	2.6	1.9	2.5	1.9
Worry too long after embarrassment	2.5	4.2	10.5	1.2	1.2	-2.1	-2.3	-2.3	-3.2	-2.4	-1.2	-2.4	-0.9	-2.3	-1.8	-1.6	-1.6	-2.4	-2.1	-2.4
High blood pressure	2.4	6.6	12.0	-1.2	-2.4	2.9	2.8	2.6	3.1	2.7	2.5	2.9	3.5	2.8	2.8	1.1	0.6	2.8	2.5	2.7
Whole body fat mass	2.4	10.0	13.2	1.6	2.3	-3.2	-3.6	-3.5	-3.3	-3.6	-2.9	-3.5	-3.0	-3.5	-2.9	-3.4	-1.3	-3.6	-3.6	-3.6
Number of full sisters	2.4	2.9	12.0	-1.3	-3.5	1.9	1.5	1.3	1.0	1.4	1.9	1.3	1.6	1.3	1.9	1.4	-0.0	1.2	2.7	1.3
Vascular/heart problems diagnosed by doctor	2.4	6.6	12.8	0.9	2.4	-2.8	-2.8	-2.7	-3.1	-2.8	-2.4	-2.9	-3.6	-2.8	-2.7	-1.2	-1.1	-2.9	-2.4	-2.7
Ever had hysterectomy (womb removed)	2.3	2.6	5.4	-0.2	0.3	-1.3	-2.2	-2.2	-1.8	-2.3	0.7	-2.3	-1.2	-2.0	-1.2	-0.6	-0.5	-2.3	-0.8	-2.3
Chronic bronchitis/emphysema (father)	2.3	2.7	16.0	0.4	2.2	-1.3	-1.5	-1.2	-4.0	-1.5	-0.6	-1.4	-0.6	-1.4	-1.8	-1.1	0.4	-1.5	-1.7	-1.5
Forced vital capacity (FVC), Best measure	2.3	8.3	14.8	3.3	2.7	-3.4	-3.1	-3.3	-2.6	-3.2	-1.0	-3.0	-2.2	-3.2	-3.9	-2.1	1.2	-3.2	-2.9	-3.1
Number of self-reported non-cancer illnesses	2.3	4.0	9.1	-2.6	-2.2	2.7	1.7	1.9	1.0	1.6	2.3	1.7	3.0	1.9	2.5	1.4	0.3	1.6	2.4	1.6
Wears glasses or contact lenses	2.3	2.6	5.5	1.9	2.0	-2.4	-1.6	-1.6	-1.1	-1.5	-1.4	-1.5	-1.3	-1.5	-2.2	-0.6	-1.1	-1.4	-2.1	-1.4
Blood clot in the leg (DVT)	2.2	2.8	4.9	1.4	0.7	-1.9	-2.0	-1.9	-2.1	-2.0	-0.6	-2.0	-2.2	-2.1	-1.6	-0.8	-0.5	-2.0	-1.3	-1.9
Leg pain on walking	2.2	2.7	8.1	-2.9	-1.2	2.3	1.5	1.6	0.9	1.5	0.3	1.3	2.0	1.7	1.7	1.7	-1.7	1.5	1.2	1.5
Hypertension (Self-reported)	2.2	6.0	11.5	-1.0	-2.1	2.7	2.6	2.5	2.8	2.6	2.6	2.7	3.4	2.6	2.6	1.0	0.9	2.7	2.4	2.5
Irritability	2.2	3.8	5.0	1.6	1.4	-2.2	-2.2	-2.2	-2.1	-2.2	-1.2	-2.1	-2.0	-2.2	-2.2	-1.8	-0.1	-2.2	-2.0	-2.2
Respiratory disease	2.1	4.7	8.9	-1.4	-2.3	2.3	2.3	2.2	1.1	2.3	2.2	2.2	2.9	2.0	1.6	3.0	1.0	2.2	2.5	2.3
Neck or shoulder pain in last month	2.1	2.9	13.2	-3.6	-2.1	2.1	0.8	1.0	0.9	0.7	0.8	0.5	0.5	1.4	2.8	1.1	-3.0	0.7	1.7	0.6
Allergy or Eczema	2.0	5.3	10.0	-2.1	-0.6	2.8	2.5	2.8	2.5	2.6	1.5	2.5	2.1	2.4	1.4	3.2	1.0	2.6	2.0	2.7
Forced expiratory volume in 1-second (FEV1)	2.0	6.7	14.1	3.8	2.2	-3.3	-2.7	-3.0	-2.1	-2.6	-1.1	-2.5	-2.0	-2.9	-3.5	-1.4	1.1	-2.7	-2.7	-2.6
Medication for cholesterol, blood pressure or diabetes	2.0	3.3	12.6	0.1	2.2	-1.6	-1.8	-1.6	-3.6	-1.9	-1.0	-1.8	-2.4	-1.6	-2.0	-0.8	0.2	-1.9	-1.6	-1.9
Risk taking	2.0	2.9	10.4	-0.2	3.2	-1.3	-1.5	-1.1	-1.2	-1.5	-2.7	-1.4	-1.5	-1.4	-2.3	-0.9	-0.6	-1.4	-2.4	-1.5
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	4.0	-0.5	-1.0	1.5	1.8	1.8	1.1	1.8	0.6	1.8	2.0	1.7	1.4	1.2	0.6	1.8	1.1	1.8
Asthma	1.9	3.8	5.7	-1.2	-1.7	2.0	2.4	2.3	1.5	2.3	0.9	2.4	2.0	2.2	1.9	1.6	0.7	2.4	2.2	2.4
Comparative height size at age 10	1.9	10.2	19.4	2.8	4.3	-3.9	-3.1	-2.9	-1.7	-3.0	-4.4	-2.7	-3.5	-2.8	-4.0	-3.0	-0.5	-2.8	-3.8	-2.9
Heart disease (siblings)	1.9	2.4	5.0	-0.1	-2.2	1.5	1.7	1.4	2.1	1.7	1.2	1.7	1.8	1.3	1.5	1.0	0.6	1.8	1.5	1.7
Major Depression (MDD)	1.8	2.2	3.5	0.5	-1.8	1.3	1.8	1.4	1.2	1.8	1.8	1.9	1.4	1.6	1.3	0.4	0.5	1.7	1.5	1.7
Chronic bronchitis/emphysema (mother)	1.8	2.1	3.9	-1.2	-1.0	1.6	1.6	1.6	0.6	1.5	1.9	1.5	1.2	1.6	1.5	1.2	0.9	1.6	2.0	1.5
Medication: Atorvastatin	1.8	2.2	6.1	1.1	-1.1	0.6	1.8	1.2	2.5	1.9	0.4	1.9	2.4	1.3	1.3	0.5	-0.2	1.9	0.9	1.8
Bipolar Disorder (2011)	1.7	1.6	3.6	-1.3	-1.6	1.2	1.2	1.1	1.1	1.1	1.7	1.1	0.2	0.9	1.4	1.9	0.0	1.2	1.9	1.1
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	4.7	-1.3	-2.2	1.5	1.6	1.4	1.2	1.5	-0.4	1.4	2.2	1.2	1.3	2.0	-0.3	1.5	1.8	1.5
Illnesses of siblings	1.7	2.4	6.5	-0.1	2.0	-1.7	-1.5	-1.4	-0.6	-1.5	-2.5	-1.5	-1.9	-1.3	-1.8	0.3	-1.6	-1.4	-1.9	-1.4
Emphysema/chronic bronchitis	1.7	1.9	7.5	-2.7	-2.2	1.6	0.4	0.4	-0.3	0.4	1.7	0.1	1.8	0.7	1.8	0.8	-2.2	0.3	1.2	0.3
Nervous feelings	1.6	3.1	6.3	-2.4	-2.1	2.5	1.6	1.7	1.1	1.4	2.2	1.5	1.6	1.9	2.5	0.8	-0.6	1.4	1.8	1.3
Hair/balding pattern: Pattern 4	1.6	4.0	7.9	-1.9	-1.8	2.4	2.1	2.2	2.2	2.2	0.9	2.0	1.4	2.4	2.8	0.3	-1.5	2.1	1.9	2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	5.0	-1.9	-1.5	1.8	1.4	1.6	1.1	1.3	0.7	1.3	1.7	1.5	1.2	2.2	0.3	1.3	1.6	1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	6.5	2.1	1.5	-2.3	-1.9	-2.0	-0.8	-2.0	-1.3	-1.8	-2.1	-2.0	-2.6	-0.9	0.2	-1.9	-2.0	-2.0
Asthma (self-reported)	1.6	3.3	4.8	-1.3	-1.6	1.9	2.1	2.1	1.4	2.1	0.7	2.2	2.0	2.0	1.8	1.4	0.5	2.2	2.0	2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	10.0	3.2	0.1	-2.5	-1.9	-2.5	-1.2	-1.9	0.9	-1.9	-1.0	-2.2	-1.9	-1.1	-0.5	-2.0	-1.4	-1.9
Medication: Omeprazole (e.g. Zanprol)	1.6	2.0	5.4	1.6	1.7	-1.9	-1.0	-1.3	0.0	-1.0	-2.3	-0.9	-2.2	-1.3	-1.8	-0.4	-1.1	-0.8	-1.5	-1.0
Vitamin and mineral supplements	1.5	2.1	5.2	-1.1	0.0	1.5	1.6	1.9	-0.9	1.6	-0.6	1.8	1.4	2.3	1.9	-0.8	0.9	1.7	0.8	1.7
Serious illness, injury or assault to yourself	1.5	1.9	6.9	-0.9	-2.6	2.1	1.3	1.2	1.6	1.2	1.1	1.2	0.6	1.0	1.6	0.8	0.7	1.1	1.5	1.1
Hayfever, allergic rhinitis or eczema	1.5	3.2	6.0	-1.6	-1.3	2.1	1.9	2.0	2.0	2.0	1.1	1.8	2.0	1.6	1.3	2.5	0.1	1.9	1.6	2.0
Weight	1.5	7.3	12.5	1.4	2.1	-2.7	-3.0	-2.8	-3.4	-3.0	-2.5	-2.9	-2.6	-2.7	-2.1	-3.5	-1.0	-3.0	-3.0	-2.9
Illnesses of mother	1.5	1.8	3.9	0.0	1.2	-1.4	-1.4	-1.4	-1.1	-1.3	-2.0	-1.4	-1.1	-1.4	-1.2	-0.7	-1.8	-1.4	-1.7	-1.3
Illnesses of siblings: Diabetes	1.5	1.8	6.4	1.5	-2.5	0.6	1.4	1.0	1.2	1.4	0.6	1.4	2.2	0.7	1.4	-0.2	0.5	1.3	1.4	1.3
Pack years adult smoking proportion	1.4	2.2	4.3	1.0	1.5	-1.6	-1.5	-1.5	-0.8	-1.5	-1.5	-1.4	-1.9	-1.5	-2.1	-0.3	-0.4	-1.5	-2.0	-1.5
Taking other prescription medications	1.4	2.2	4.9	-0.9	-2.2	1.7	1.5	1.6	1.7	1.4	1.3	1.5	1.7	1.5	1.7	0.9	0.1	1.4	1.8	1.4
Number of live births	1.4	2.0	9.2	1.2	2.1	-1.4	-1.2	-1.1	-3.0	-1.1	-0.2	-1.0	-0.6	-1.0	-1.2	-2.1	1.3	-1.1	-1.0	-1.1
Commuting to job workplace: Car/motor vehicle	1.4	1.6	4.8	0.5	1.7	-1.2	-0.9	-0.8	-1.4	-0.8	-2.2	-0.7	-1.4	-0.6	-0.7	-2.0	-1.5	-0.8	-1.7	-0.7
Friendships satisfaction	1.4	1.7	3.1	-1.2	-0.8	1.5	1.4	1.5	0.6	1.4	1.3	1.4	1.8	1.7	1.6	0.2	0.6	1.4	1.4	1.4
Fractured/broken bones in last 5 years	1.4	1.8	5.6	1.6	1.2	-1.3	-1.1	-1.0	-0.5	-1.1	-0.9	-1.1	-1.4	-1.5	-2.4	0.7	2.2	-1.0	-1.4	-1.1
Pain experienced in last month	1.4	2.3	16.7	4.1	1.1	-2.2	-0.4	-0.9	0.5	-0.3	0.0	-0.2	-0.8	-1.2	-2.0	-1.4	2.4	-0.4	-0.9	-0.3
Leg fat mass (left)	1.4	5.3	8.2	0.9	1.5	-2.2	-2.7	-2.5	-2.9	-2.6	-1.7	-2.6	-2.4	-2.5	-1.9	-2.6	-1.0	-2.7	-2.5	-2.6
Impedance of leg (left)	1.3	6.4	13.2	2.3	3.1	-3.2	-2.7	-2.7	-1.2	-2.6	-1.3	-2.6	-2.8	-2.9	-3.6	-1.2	1.3	-2.6	-2.6	-2.6
Qualifications: College or University degree	1.3	4.0	10.7	-1.8	-1.7	2.3	1.7	1.8	1.6	1.7	3.0	1.7	2.6	2.0	3.3	-0.1	-1.2	1.7	2.1	1.7
Had major operations	1.3	1.6	6.4	-0.8	1.4	-0.7	-1.0	-0.7	-1.0	-0.9	-2.5	-1.0	-0.2	-0.5	-1.0	-0.1	-2.4	-0.9	-2.0	-0.9
Average weekly champagne plus white wine intake	1.3	1.8	3.7	0.1	0.4	-0.9	-1.7	-1.7	-1.9	-1.7	1.7	-1.7	-1.0	-1.4	-0.5	-1.3	-0.2	-1.7	-0.8	-1.7
Age started oral contraceptive pill	1.3	1.7	4.9	-2.1	-2.2	1.6	0.5	0.6	1.4	0.5	0.3	0.2	1.9	0.3	1.3	1.9	-1.7	0.4	1.0	0.4
Bipolar Disorder (2018)	1.2	1.9	4.9	-2.2	-1.2	1.6	1.4	1.6	0.0	1.4	0.6	1.1	1.1	1.3	1.4	2.2	0.4	1.4	1.6	1.4
Coronary Artery Disease (CAD)	1.2	1.4	4.2	0.3	-1.2	0.8	1.4	0.9	1.6	1.5	0.4	1.4	1.2	0.9	0.3	2.1	0.1	1.4	1.0	1.6
HbA1C	1.2	1.4	3.4	-0.3	-1.1	1.0	1.2	1.1	1.4	1.3	1.1	1.1	1.3	0.9	0.7	1.8	-0.3	1.2	1.5	1.4
Lupus	1.2	1.9	5.1	1.1	1.2	-1.9	-1.2	-1.4	-1.3	-1.1	-1.4	-1.3	-1.4	-1.3	-2.3	0.1	-0.5	-1.1	-1.9	-1.2
Forced vital capacity (FVC)	1.2	4.6	10.0	2.8	2.4	-2.6	-2.2	-2.3	-1.7	-2.2	-1.1	-2.1	-1.4	-2.2	-3.2	-1.1	1.2	-2.2	-2.2	-2.2
Qualifications: A levels/AS levels or equivalent	1.2	2.7	6.5	-1.9	-1.8	2.1	1.4	1.6	1.8	1.4	1.1	1.3	2.5	1.6	2.5	0.3	-0.9	1.4	1.4	1.4
High blood pressure (siblings)	1.2	1.7	4.7	-0.1	-1.6	1.4	1.4	1.2	0.7	1.3	2.2	1.4	0.6	1.3	1.6	-0.3	1.0	1.2	1.8	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	3.8	-0.8	0.1	1.2	1.4	1.6	0.3	1.3	0.4	1.5	0.2	1.6	1.1	-0.1	2.0	1.3	1.4	1.4
Leg fat mass (right)	1.2	4.8	6.7	0.8	1.3	-2.1	-2.6	-2.5	-2.4	-2.5	-1.6	-2.5	-2.3	-2.5	-1.8	-2.5	-1.2	-2.6	-2.5	-2.5
Arm fat percentage (left)	1.2	4.8	6.8	0.8	1.4	-2.1	-2.5	-2.5	-2.6	-2.5	-1.9	-2.5	-1.9	-2.5	-2.0	-2.1	-1.4	-2.5	-2.6	-2.5
Eye problems/disorders: Cataract	1.2	1.4	4.5	-0.7	0.2	1.5	1.2	1.4	0.9	1.2	1.3	1.2	1.3	1.2	0.3	0.7	2.1	1.2	1.1	1.2
Arm fat mass (left)	1.2	5.0	8.2	0.9	1.3	-2.1	-2.6	-2.4	-2.9	-2.5	-2.0	-2.5	-1.8	-2.5	-1.9	-2.4	-1.2	-2.5	-2.6	-2.5
Pack years of smoking	1.2	1.8	3.4	1.1	1.4	-1.5	-1.4	-1.4	-0.6	-1.5	-1.3	-1.4	-1.6	-1.4	-1.8	-0.4	-0.5	-1.4	-1.8	-1.5
Hearing difficulty/problems: Yes	1.1	1.7	3.0	-0.9	-0.9	1.4	1.4	1.5	0.8	1.3	1.6	1.4	1.1	1.4	1.2	1.7	0.5	1.4	1.7	1.3
Hand grip strength (right)	1.1	3.0	8.9	1.9	2.3	-1.9	-1.7	-1.6	-1.7	-1.6	-0.5	-1.5	-1.8	-1.4	-1.6	-3.0	0.3	-1.6	-1.9	-1.6
Maternal smoking around birth	1.1	1.7	6.2	1.4	1.3	-1.3	-1.0	-1.0	-2.0	-1.0	0.9	-0.9	-2.5	-1.0	-1.2	-1.1	1.2	-1.0	-1.0	-1.0
Supplements: Glucosamine	1.1	1.5	5.3	-2.3	-0.1	1.6	1.0	1.4	0.8	1.0	1.2	0.9	0.8	1.3	1.0	1.8	-0.2	1.0	1.2	1.1
Medication: Atenolol	1.1	1.4	2.7	1.6	1.6	-1.4	-1.2	-1.2	-0.2	-1.0	-0.9	-1.1	-0.2	-1.3	-1.4	-0.9	-1.1	-1.0	-1.5	-1.0
Arm fat mass (right)	1.1	4.7	8.1	0.7	1.3	-2.0	-2.5	-2.4	-2.8	-2.5	-2.1	-2.5	-1.9	-2.4	-1.7	-2.3	-1.3	-2.5	-2.4	-2.4
Pulse wave peak to peak time	1.1	1.3	4.9	-2.2	-0.1	0.0	-0.9	-0.7	-0.3	-1.0	-1.9	-1.2	-0.8	-0.6	-0.1	1.3	-2.2	-0.9	-0.7	-1.0
Eye problems/disorders: None of the above	1.1	1.2	2.6	0.0	-0.3	-1.0	-1.2	-1.4	-1.5	-1.3	-0.9	-1.3	-1.6	-1.1	0.1	-0.6	-1.4	-1.3	-0.6	-1.3
Overall health rating	1.1	2.4	10.0	-3.2	-1.9	2.2	1.1	1.3	0.1	1.1	0.5	1.0	0.7	1.6	2.2	1.3	-1.5	1.0	1.8	1.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.3	0.9	0.4	-1.3	-1.3	-1.3	-1.5	-1.3	-0.4	-1.4	-1.8	-1.5	-1.2	-0.3	-0.2	-1.3	-0.8	-1.3
Intelligence (Savage-Jansen 2018)	1.0	3.0	8.5	-1.5	-1.2	1.1	1.7	1.8	2.1	1.7	0.1	1.7	2.9	2.0	2.1	1.3	-1.5	1.8	1.6	1.7
Alzheimer’s Disease (in father)	1.0	1.0	3.5	-1.3	0.0	0.5	0.8	0.7	1.2	0.9	0.8	0.9	1.9	1.0	1.3	0.4	-1.6	1.0	0.8	0.9
HDL Cholesterol	1.0	1.6	4.8	-1.9	-1.5	1.5	1.0	0.9	0.5	0.7	2.2	1.0	0.9	1.3	2.1	-0.7	-0.0	0.7	1.5	0.5
Neuroticism (2016)	1.0	1.4	2.8	-0.3	-0.6	1.1	1.5	1.2	1.1	1.5	1.1	1.7	1.2	1.2	1.3	0.4	0.9	1.5	1.2	1.5
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	3.2	-0.3	0.9	-0.6	-1.3	-1.1	-1.2	-1.3	0.1	-1.2	-0.6	-1.0	-0.3	-1.8	-0.2	-1.4	-1.1	-1.4
Multivitamins +/- minerals	1.0	1.3	2.6	0.1	-0.5	-0.7	-1.1	-1.4	1.6	-1.1	0.3	-1.3	-1.0	-1.6	-1.1	1.4	-1.4	-1.2	-0.5	-1.1
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	6.8	-1.4	-1.5	1.2	1.1	1.1	0.9	0.9	1.3	1.0	0.3	1.1	0.7	2.6	0.6	1.0	1.6	0.9
Pulse rate	1.0	1.7	2.8	0.0	-1.4	1.4	1.4	1.4	1.4	1.4	1.3	1.4	1.7	1.4	1.4	0.6	0.8	1.4	1.0	1.4
Pulse wave Arterial Stiffness index	1.0	1.1	7.2	2.7	0.9	-0.8	0.3	0.1	-0.3	0.4	1.3	0.6	0.3	-0.0	-0.6	-1.8	2.0	0.3	-0.0	0.4
Depressed Affect (Nagel 2018)	0.9	1.9	4.4	0.6	1.6	-1.7	-1.4	-1.3	-2.1	-1.4	-0.9	-1.3	-1.3	-1.1	-1.6	-1.1	-0.6	-1.3	-1.6	-1.4
Ovarian Cancer	0.9	1.3	4.6	0.1	-2.1	0.8	1.2	1.0	1.2	1.2	-0.5	1.1	1.5	0.8	1.4	0.6	0.0	1.1	1.3	1.1
Primary Biliary Cirrhosis	0.9	1.3	3.3	0.9	1.8	-1.1	-1.0	-0.9	-0.7	-0.9	-1.4	-0.9	-1.3	-1.1	-1.7	-0.6	0.0	-0.9	-1.7	-0.9
Number of treatments/medications taken	0.9	1.6	3.5	-1.4	-1.8	1.6	1.0	1.1	1.4	1.0	1.5	1.0	1.9	1.0	1.4	1.0	-0.3	1.0	1.4	0.9
Relative age of first facial hair	0.9	1.9	4.2	0.4	1.8	-1.3	-1.4	-1.3	-1.3	-1.3	-1.7	-1.3	-0.4	-1.2	-1.0	-2.0	-1.6	-1.3	-1.7	-1.3
Impedance of leg (right)	0.9	4.2	10.4	2.1	2.6	-2.5	-2.1	-2.0	-0.2	-2.0	-0.8	-2.0	-2.1	-2.4	-3.2	-1.1	1.7	-2.0	-2.2	-2.0
Qualifications: None of the above	0.9	1.9	8.1	2.8	1.2	-1.7	-0.9	-1.1	-1.4	-0.9	-1.3	-0.7	-0.6	-1.4	-1.8	-1.7	1.5	-0.9	-1.0	-0.9
Allergy	0.9	2.1	4.8	1.6	1.4	-1.7	-1.5	-1.5	-1.4	-1.5	-1.1	-1.3	-1.7	-1.2	-1.3	-2.2	0.1	-1.5	-1.6	-1.5
Happiness	0.9	1.1	2.3	1.3	0.2	-1.5	-1.0	-1.3	-0.6	-0.9	-1.5	-1.0	-1.2	-1.0	-1.4	-0.1	-0.9	-1.0	-1.0	-1.0
Noisy workplace	0.9	1.1	3.0	1.7	0.6	-1.2	-0.9	-1.2	0.4	-1.0	-0.4	-0.9	-0.8	-1.4	-1.6	-0.5	0.8	-0.9	-1.1	-1.0
Breastfed as a baby	0.9	1.1	1.9	-0.9	-0.3	1.3	1.3	1.4	0.2	1.4	-0.4	1.3	1.1	1.3	0.8	0.3	0.7	1.4	0.8	1.3
Birth weight	0.9	1.8	3.7	1.5	1.3	-1.5	-1.2	-1.2	-1.2	-1.2	-1.7	-1.2	-1.9	-1.2	-1.5	-1.0	-0.6	-1.1	-1.9	-1.1
Number of children fathered	0.9	1.0	2.6	0.2	1.1	-0.5	-1.1	-0.8	-1.3	-1.0	-0.7	-1.1	-0.9	-0.9	-1.2	-1.2	-0.4	-1.0	-1.6	-1.0
Mean time to correctly identify matches	0.9	1.7	2.8	0.1	0.6	-1.2	-1.5	-1.5	-0.8	-1.4	-1.6	-1.5	0.1	-1.5	-1.6	0.1	-1.7	-1.5	-1.6	-1.5
Knee pain experienced in last month	0.9	1.4	3.2	-1.4	1.3	0.0	-1.1	-0.7	-1.5	-1.2	-1.8	-1.1	-1.6	-0.7	-1.0	0.9	-1.2	-1.0	-1.1	-1.1
Qualifications: nursing, teaching	0.9	1.4	4.3	-1.7	-0.6	1.7	1.0	1.2	2.1	1.1	1.0	0.9	1.3	1.0	1.2	0.8	-0.3	1.1	1.0	1.1
Mineral and other dietary supplements	0.9	1.2	5.4	2.3	0.2	-1.4	-0.7	-1.0	-0.9	-0.7	-1.8	-0.6	-1.2	-0.8	-0.6	-1.6	0.1	-0.6	-1.1	-0.8
Leg fat percentage (left)	0.9	3.1	6.1	0.6	1.1	-1.5	-2.1	-2.0	-2.3	-2.0	-0.8	-2.0	-1.9	-2.0	-1.2	-2.5	-0.4	-2.1	-1.9	-2.0
Commuting to job workplace: Cycle	0.9	1.1	3.5	0.3	-0.8	1.0	0.9	0.9	0.5	0.8	1.9	1.0	1.7	0.7	0.7	-0.1	1.7	0.8	1.0	0.8
Cholesterol lowering medication	0.9	1.3	2.7	0.9	-1.1	0.6	1.4	1.1	0.8	1.4	1.1	1.4	1.6	0.9	0.7	0.9	1.3	1.4	1.2	1.4
Ever used hormone-replacement therapy (HRT)	0.8	1.0	4.0	-1.2	-0.8	1.2	0.8	0.9	0.6	0.8	1.0	0.7	1.8	0.7	0.3	2.0	-0.2	0.7	0.9	0.8
Supplements: Zinc	0.8	0.8	2.9	-1.4	-1.3	0.5	-0.1	-0.1	1.4	-0.2	1.4	-0.2	-0.1	0.1	1.3	0.1	-1.7	-0.2	1.1	-0.2
Townsend deprivation index at recruitment	0.8	1.1	3.3	1.3	0.5	-1.7	-0.8	-1.0	-1.8	-0.9	-1.3	-0.8	-0.4	-0.9	-1.3	-0.3	-0.6	-0.8	-1.0	-0.9
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.7	0.5	0.8	-0.4	-1.0	-0.9	-1.3	-1.1	-0.4	-1.0	-0.8	-0.9	-1.2	-0.4	-0.1	-1.1	-1.2	-1.1
High blood pressure (mother)	0.8	1.2	3.0	0.0	-0.9	1.0	1.2	1.2	1.3	1.2	0.6	1.2	0.6	1.1	0.6	1.7	1.1	1.2	1.2	1.2
Alcohol usually taken with meals	0.8	1.2	2.5	-0.7	-0.9	1.6	1.1	1.2	1.4	1.2	1.1	1.1	1.1	1.1	1.3	-0.0	0.8	1.1	1.0	1.2
Arm fat percentage (right)	0.8	3.2	4.6	0.4	1.0	-1.6	-2.1	-2.1	-2.1	-2.1	-1.6	-2.0	-1.6	-2.0	-1.5	-1.9	-1.2	-2.1	-2.0	-2.1
Tense / ‘highly strung’	0.8	1.4	3.9	-0.8	-2.0	1.3	1.0	0.9	0.8	0.8	2.0	1.0	0.6	1.1	2.0	-0.2	-0.3	0.8	1.6	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	3.4	-1.2	-1.1	1.2	1.0	1.0	0.4	0.9	1.9	0.9	1.3	1.2	0.9	1.6	0.9	0.9	1.4	0.9
Peak expiratory flow (PEF)	0.8	1.8	3.6	-0.5	-1.5	1.7	1.4	1.2	0.9	1.4	1.9	1.3	1.8	1.4	1.3	0.8	0.4	1.3	1.6	1.4
Headache pain in last month	0.8	1.4	4.2	-0.9	-2.1	1.5	1.1	1.0	0.1	1.0	1.6	0.9	1.0	1.1	1.2	1.8	-0.6	1.0	1.4	0.9
Glaucoma (self-reported)	0.8	0.9	3.2	1.5	-0.2	0.1	0.9	0.7	0.8	1.0	0.1	1.1	1.8	0.4	-0.4	0.9	1.7	1.0	0.3	1.0
Mouth/teeth dental problems: Loose teeth	0.8	0.9	3.8	-0.3	1.7	-0.4	-0.6	-0.4	0.7	-0.6	-1.1	-0.5	-0.7	-0.5	-1.6	1.9	-0.2	-0.4	-1.4	-0.6
Medication: Seretide 50 evohaler	0.8	0.9	1.7	-0.8	-0.5	-0.8	-1.1	-1.0	-1.0	-1.2	0.9	-1.3	0.8	-1.1	-0.4	0.1	-1.1	-1.2	-0.3	-1.2
Long-standing illness, disability or infirmity	0.8	1.1	4.5	-1.4	-2.1	1.2	0.8	0.7	0.6	0.7	0.9	0.7	1.2	0.7	1.3	0.8	-1.2	0.6	1.3	0.7
Medication: Aspirin	0.8	1.0	6.2	-0.3	-1.1	1.0	0.8	0.8	1.6	0.9	-0.5	0.7	2.5	0.6	1.0	-0.3	-0.6	0.8	0.5	0.8
Alcohol drinker status: Never	0.8	0.9	1.5	-0.2	-0.8	-0.3	-1.0	-0.9	-1.1	-1.1	-1.2	-1.2	-1.2	-1.2	-0.9	1.1	-0.6	-1.1	-0.7	-1.1
Unable to work because of sickness or disability	0.8	1.0	1.8	-0.5	-0.5	1.0	1.3	1.3	1.1	1.3	0.3	1.3	0.3	1.2	0.6	1.0	0.9	1.2	0.8	1.3
Neuroticism	0.7	1.6	3.1	0.1	0.2	-1.3	-1.5	-1.5	-1.8	-1.6	-0.3	-1.6	-0.5	-1.4	-1.2	-0.6	-1.1	-1.6	-1.2	-1.7
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.9	-0.2	-1.3	0.0	0.6	0.4	1.4	0.6	0.8	0.5	1.2	0.5	1.1	0.1	-1.7	0.6	0.8	0.6
Fed-up feelings	0.7	1.3	3.2	0.5	1.8	-1.5	-1.2	-1.1	-1.2	-1.2	-0.5	-1.1	-1.3	-0.9	-1.3	-0.7	-0.6	-1.2	-1.2	-1.2
Hip circumference	0.7	3.2	6.6	-0.7	1.2	-1.2	-1.9	-1.6	-2.4	-1.9	-2.5	-1.8	-1.0	-1.3	-0.6	-2.6	-2.3	-1.8	-2.0	-1.9
Leg fat percentage (right)	0.7	2.4	5.6	0.5	0.8	-1.3	-1.8	-1.7	-1.6	-1.8	-0.6	-1.8	-1.7	-1.8	-1.2	-2.4	-0.3	-1.9	-1.8	-1.8
Medication: Omeprazole	0.7	0.9	4.4	0.8	1.4	-1.1	-0.5	-0.6	0.1	-0.4	-2.1	-0.4	-1.3	-0.5	-1.1	-0.4	-1.0	-0.3	-1.0	-0.4
Illnesses of father: Heart disease	0.7	1.0	4.7	-0.3	-2.2	0.9	0.5	0.2	0.9	0.5	0.6	0.3	1.6	0.6	1.1	1.0	-1.9	0.4	1.0	0.4
Osteoarthritis (self-reported)	0.7	1.0	4.4	-2.1	-0.7	1.2	0.4	0.7	-0.6	0.3	1.2	0.3	0.7	0.7	0.7	2.1	-0.1	0.3	1.1	0.4
Leg predicted mass (right)	0.7	3.7	8.4	1.3	1.1	-2.1	-2.1	-2.0	-2.9	-2.1	-2.1	-2.0	-1.7	-1.9	-1.5	-1.9	-1.3	-2.1	-1.9	-2.1
Medication: Blood pressure	0.7	1.2	3.9	-1.3	-1.0	1.3	1.1	1.2	0.0	1.1	1.0	1.1	2.0	1.2	1.3	0.7	-0.0	1.2	0.7	1.0
Neuroticism (Nagel 2018)	0.6	1.4	3.9	-0.2	0.5	-1.1	-1.3	-1.4	-2.0	-1.4	-0.4	-1.3	-0.7	-1.1	-0.8	-0.8	-1.3	-1.7	-1.2	-1.4
Breast Cancer	0.6	1.4	3.7	1.9	0.3	-1.4	-1.0	-1.1	-1.9	-0.9	-0.1	-1.1	-1.0	-1.6	-1.7	0.2	1.0	-0.9	-0.9	-0.9
Fasting Glucose	0.6	0.7	4.8	2.2	-0.2	-1.1	-0.1	-0.4	-0.0	-0.4	-1.3	-0.1	-0.9	-0.8	-1.3	0.2	0.7	-0.2	-0.8	-0.5
Blood White Count	0.6	4.7	9.5	0.1	-2.4	1.9	2.6	2.1	1.6	2.7	2.0	2.5	3.1	2.2	2.2	1.0	0.2	2.6	2.1	2.8
Hand grip strength (left)	0.6	1.6	7.5	2.3	1.3	-1.5	-0.8	-0.9	-1.0	-0.8	0.9	-0.6	-1.5	-0.7	-0.7	-2.7	1.2	-0.8	-0.8	-0.8
Frequency of depressed mood in last 2 weeks	0.6	0.9	4.3	-2.1	-0.5	0.5	0.7	0.9	0.6	0.6	-0.1	0.7	0.0	1.2	0.9	1.5	-1.0	0.7	1.0	0.7
Leg fat-free mass (left)	0.6	3.0	5.2	1.3	1.0	-1.9	-1.8	-1.8	-2.3	-1.8	-1.9	-1.8	-1.4	-1.7	-1.5	-1.8	-1.1	-1.8	-1.9	-1.8
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.2	-0.8	1.2	-0.1	-0.7	-0.4	-1.4	-0.7	-1.5	-0.6	-0.3	-0.5	-0.4	-0.5	-0.6	-0.7	-1.1	-0.7
Fluid intelligence score	0.6	1.3	4.1	0.0	-0.1	0.5	1.2	1.2	1.5	1.3	0.6	1.4	2.0	1.5	1.4	0.1	-0.7	1.3	0.5	1.3
Father’s age at death	0.6	0.8	4.7	-2.2	0.6	1.0	0.2	0.5	1.3	0.2	0.5	0.1	0.6	0.7	0.5	0.9	-1.7	0.3	0.2	0.2
Leg fat-free mass (right)	0.6	3.3	7.6	1.2	1.1	-2.0	-2.0	-1.9	-2.8	-1.9	-2.0	-1.9	-1.6	-1.7	-1.3	-1.9	-1.3	-1.9	-1.8	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	4.9	1.0	1.4	-0.2	0.0	0.2	-0.9	0.1	-0.6	0.3	-0.1	0.4	0.0	-2.2	0.7	0.1	-0.6	0.1
Back pain experienced in last month	0.6	0.8	3.6	-1.9	-1.3	0.6	-0.5	-0.4	-1.1	-0.7	-0.2	-0.7	-0.7	-0.3	1.0	-0.6	-1.4	-0.7	0.4	-0.7
Supplements: Calcium	0.6	0.6	4.0	-0.3	-1.4	0.5	0.3	0.3	2.0	0.3	-0.3	0.2	-0.6	0.3	1.3	-0.4	-0.6	0.3	1.0	0.3
Alzheimer’s Disease (in mother)	0.5	0.6	2.5	0.1	0.9	-0.5	-0.6	-0.5	0.2	-0.7	-1.6	-0.6	-1.2	-0.4	-0.9	-1.2	-0.1	-0.6	-0.6	-0.7
Alzheimer’s Disease (including proxy)	0.5	0.7	4.0	-0.1	1.2	-1.1	-0.7	-0.6	0.2	-0.6	-2.0	-0.6	0.0	-0.5	-0.8	-0.9	-1.1	-0.4	-0.9	-0.6
Verbal and Numeric Reasoning (VNR)	0.5	1.2	4.0	0.3	1.0	0.2	1.3	1.4	1.2	1.4	0.0	1.5	2.0	1.3	0.4	0.3	0.2	1.5	0.2	1.5
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.6	1.6	-0.2	-0.9	-0.7	-0.9	-0.2	-0.6	0.1	-0.5	-0.6	-1.1	-0.8	-1.0	0.8	-0.7	-0.6	-0.6
Ulcerative Colitis	0.5	0.7	4.5	-0.8	2.1	-0.2	-0.5	-0.2	-1.6	-0.5	-0.1	-0.3	-1.3	0.2	-0.1	-1.3	0.3	-0.3	-0.5	-0.5
Blood Red Count	0.5	4.9	11.3	3.4	1.5	-3.2	-2.0	-2.3	-0.3	-1.8	-3.1	-1.8	-1.4	-2.0	-2.4	-2.3	-2.0	-1.9	-2.7	-1.7
Systolic Blood Pressure	0.5	2.6	4.9	0.7	-1.1	0.7	1.7	1.4	1.9	1.9	2.1	1.8	2.2	1.2	0.7	0.9	2.1	1.8	1.8	1.9
Chronotype (morning person)	0.5	1.2	5.0	1.7	-0.5	0.3	1.2	0.9	1.3	1.2	1.2	1.3	0.3	0.8	-0.2	0.3	2.2	1.1	1.1	1.2
Sensitivity / hurt feelings	0.5	0.8	2.3	0.8	0.1	-1.0	-0.9	-1.0	-1.3	-1.0	-1.5	-0.9	0.3	-0.9	-0.9	-0.2	-0.6	-1.0	-0.8	-1.0
Medication for hormone replacement therapy	0.5	0.6	1.7	-0.4	-0.4	0.9	0.7	0.7	0.7	0.7	1.3	0.8	0.6	0.7	0.4	-0.1	1.3	0.7	0.9	0.7
Diabetes (mother)	0.5	0.6	2.1	1.0	-0.4	0.5	0.9	0.7	1.4	1.0	0.4	1.0	0.6	0.6	0.5	-0.2	0.7	1.0	0.6	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.2	-1.1	-0.9	1.5	1.2	1.3	-0.1	1.1	0.0	1.1	1.4	1.3	1.3	-0.1	0.1	1.2	0.9	1.1
Leg predicted mass (left)	0.5	2.9	5.1	1.3	1.0	-1.9	-1.8	-1.8	-2.3	-1.8	-1.9	-1.7	-1.4	-1.7	-1.5	-1.8	-1.0	-1.8	-1.9	-1.8
Pain all over the body in last month	0.5	0.5	2.0	-0.1	0.5	0.3	0.6	0.7	-0.7	0.6	-1.4	0.6	1.1	0.6	-0.4	0.9	1.1	0.6	-0.0	0.6
Falls in the last year	0.5	0.6	1.8	0.0	-1.0	1.0	0.9	0.9	0.6	0.9	0.4	0.9	0.9	1.0	0.3	0.0	1.4	0.8	0.6	0.8
Exposure to tobacco smoke at home	0.5	0.5	1.8	0.3	-0.0	-0.4	-0.6	-0.6	0.8	-0.5	-0.6	-0.6	0.7	-0.7	-1.0	1.3	-1.3	-0.6	-0.5	-0.4
Loud music exposure frequency	0.5	0.6	1.6	-0.5	0.8	-0.2	-0.7	-0.5	-0.1	-0.7	-0.7	-0.7	-1.1	-0.2	-0.3	-1.2	-1.2	-0.8	-1.1	-0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	4.4	-0.1	0.8	-0.6	-0.4	-0.4	-0.3	-0.3	-0.5	-0.5	0.7	-0.7	-1.6	2.1	0.2	-0.3	-0.8	-0.3
Medication: Paracetamol	0.5	0.9	2.5	1.0	-0.3	-0.9	-1.0	-1.1	-0.3	-1.1	-0.9	-1.1	-1.6	-1.2	-1.0	0.5	-0.2	-1.0	-0.6	-1.1
Number of full brothers	0.5	0.6	2.0	-0.2	-0.9	0.9	0.8	0.5	0.9	0.7	1.4	0.7	0.1	0.4	0.4	0.8	1.1	0.6	1.1	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.5	-1.2	-0.5	0.0	-0.8	-0.7	-0.6	-0.9	0.2	-1.0	-1.0	-0.6	0.2	-0.4	-0.8	-1.0	-0.5	-0.9
Shortness of breath walking on level ground	0.5	0.6	6.2	-1.3	-0.6	0.3	-0.4	-0.4	0.3	-0.4	-0.1	-0.5	0.8	-0.1	0.6	-0.5	-2.5	-0.3	0.1	-0.5
Age at last live birth	0.5	0.8	2.0	-0.6	1.1	-0.5	-1.0	-0.8	-0.2	-0.9	-1.4	-1.1	-0.7	-0.4	-0.5	-0.5	-1.1	-1.1	-1.2	-0.8
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	1.1	1.2	-0.8	-0.7	-0.6	-0.9	-0.7	-0.1	-0.6	-0.8	-0.7	-0.6	-0.7	1.0	-0.7	-0.5	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.2	0.1	-0.2	0.6	0.9	1.1	1.1	1.0	-0.5	1.0	-0.1	0.8	0.1	0.8	0.9	1.0	0.2	1.0
Osteoporosis (self-reported)	0.5	0.6	1.2	0.2	0.5	-0.4	-1.0	-0.9	-0.1	-0.9	0.5	-1.1	-0.6	-1.1	-1.1	-0.3	0.4	-1.1	-0.6	-0.9
Ever taken oral contraceptive pill	0.5	0.6	1.8	-0.5	-0.6	0.6	0.8	0.8	1.4	0.8	0.2	0.8	0.9	0.8	0.2	1.2	0.1	0.8	0.7	0.9
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.6	0.3	0.5	-0.8	-0.8	-0.8	-0.5	-0.9	0.1	-0.9	-0.2	-1.0	-0.6	-1.3	-0.2	-0.8	-0.9	-0.9
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.8	-1.4	-0.6	0.8	0.7	0.7	0.2	0.6	0.4	0.6	-0.5	0.8	0.8	1.3	-0.7	0.7	1.2	0.6
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.7	-1.0	0.5	-0.3	-0.8	-0.7	-0.7	-0.8	1.7	-0.9	0.2	-0.8	-1.0	0.9	-0.1	-0.9	-0.2	-0.8
Average weekly beer plus cider intake	0.5	0.7	3.0	0.9	0.8	-0.9	-0.5	-0.6	-0.7	-0.6	-1.2	-0.5	-1.7	-0.6	-0.9	-0.1	0.8	-0.5	-0.9	-0.6
Bipolar Disorder or Schizophrenia	0.4	0.9	4.8	-2.2	-1.4	1.3	0.3	0.5	-0.9	0.2	0.1	0.1	0.6	0.3	0.6	1.8	0.2	0.2	1.1	0.1
Age at First Birth	0.4	0.5	2.7	-0.5	-1.4	1.0	0.0	0.1	1.6	-0.0	1.2	-0.2	0.2	-0.1	1.0	-0.2	-0.2	-0.0	0.5	-0.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.5	-1.5	-1.6	0.8	0.1	0.2	-0.7	0.0	0.5	-0.0	0.2	0.1	0.8	0.5	-1.2	-0.0	0.6	0.0
Average weekly fortified wine intake	0.4	0.4	1.2	-1.1	0.1	-0.2	-0.8	-0.5	-0.7	-0.9	-0.2	-0.9	-0.4	-0.5	-0.5	0.5	-0.8	-0.8	-0.6	-0.9
Relative age voice broke	0.4	0.5	4.5	-1.4	-0.1	0.4	0.2	0.2	0.6	0.2	-0.9	0.1	0.6	0.3	0.6	0.5	-2.1	0.3	-0.0	0.2
Qualifications: CSEs or equivalent	0.4	0.6	3.1	1.8	-0.8	-0.6	-0.1	-0.5	1.4	-0.1	-1.2	-0.1	-0.8	-0.5	-0.5	-0.2	0.3	-0.1	-0.8	-0.1
Waist circumference	0.4	1.5	3.8	-0.4	0.6	-0.6	-1.3	-1.2	-2.0	-1.3	-1.3	-1.3	-1.2	-1.0	-0.3	-1.9	-0.9	-1.3	-1.2	-1.3
Number of incorrect matches in round	0.4	0.7	2.4	0.0	1.0	-0.6	-0.7	-0.5	-1.6	-0.7	0.0	-0.7	-0.5	-0.8	-1.3	0.9	1.3	-0.7	-0.6	-0.7
Hair/balding pattern: Pattern 2	0.4	0.5	4.0	0.4	-1.3	-0.2	-0.4	-0.6	-0.3	-0.4	0.5	-0.5	0.3	-0.5	0.3	0.4	-2.0	-0.4	-0.0	-0.4
Had menopause	0.4	0.5	1.4	0.5	-0.1	0.1	0.8	0.8	-0.1	0.8	-0.7	0.8	1.0	0.4	-0.4	1.2	1.0	0.8	0.5	0.8
Heart attack	0.4	0.5	1.7	0.9	-0.7	0.1	0.7	0.5	0.7	0.7	0.4	0.8	0.5	0.4	0.6	-0.3	1.3	0.7	0.7	0.7
Length of working week for main job	0.4	0.5	1.6	0.9	-0.2	-0.4	-0.7	-0.7	-0.2	-0.7	-0.7	-0.6	-1.3	-0.9	-0.9	0.5	-0.1	-0.7	-0.6	-0.6
Pulse wave reflection index	0.4	0.5	3.3	1.2	0.1	-0.4	0.1	-0.1	-0.4	0.1	1.4	0.2	-0.2	-0.2	-0.3	-0.5	1.8	0.0	0.8	0.0
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	2.8	-0.4	0.4	-0.5	-1.0	-0.8	0.1	-1.1	0.7	-1.0	-0.5	-0.7	-0.1	-1.7	-1.0	-1.1	-0.6	-1.1
Medication: Blood pressure	0.4	0.8	5.3	0.8	-1.1	0.5	0.8	0.5	2.3	0.9	0.1	0.8	1.0	0.5	0.5	0.6	0.1	0.9	0.6	0.9
Migraine (self-reported)	0.4	0.5	1.6	1.3	0.0	-0.9	-0.7	-0.8	-0.7	-0.7	0.4	-0.7	0.6	-1.0	-0.7	-0.8	-0.3	-0.7	-0.4	-0.8
Medication: Ibuprofen	0.4	0.5	3.5	-1.9	0.1	0.4	-0.2	0.1	-0.7	-0.2	-0.4	-0.4	-1.0	0.1	0.7	0.2	-1.4	-0.2	-0.0	-0.2
Medication: Aspirin	0.4	0.6	4.9	0.4	-0.5	0.4	0.4	0.4	1.1	0.5	-0.9	0.4	2.2	0.2	0.4	-0.8	-0.3	0.5	-0.2	0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.4	1.2	-0.4	-0.8	-0.9	-1.0	-0.5	-0.9	1.1	-0.9	-0.9	-1.1	-0.7	0.1	0.1	-0.9	-0.3	-0.9
Mother’s age at death	0.4	0.5	2.7	0.1	0.4	0.4	0.3	0.4	1.6	0.4	0.9	0.4	1.4	0.4	0.7	-0.5	-0.3	0.4	-0.3	0.4
Illnesses of father: High blood pressure	0.4	0.5	2.9	0.5	-1.7	0.1	0.2	-0.0	-0.7	0.1	1.1	0.1	0.3	0.3	1.0	-0.8	-0.9	0.1	0.9	0.1
Basal metabolic rate	0.4	2.4	5.5	1.2	0.9	-1.6	-1.6	-1.5	-2.4	-1.6	-1.3	-1.5	-1.5	-1.4	-1.0	-2.4	-0.4	-1.6	-1.5	-1.6
Basal cell carcinoma (self-reported)	0.4	0.5	3.7	0.4	-0.9	0.4	0.4	0.2	1.9	0.4	0.4	0.4	1.1	-0.1	0.2	-0.5	-0.7	0.4	0.2	0.4
Alcohol drinker status: Previous	0.4	0.4	2.1	-0.0	-0.6	-0.4	-0.4	-0.6	0.5	-0.5	-0.3	-0.5	-1.1	-0.5	-0.6	1.4	-1.1	-0.4	-0.2	-0.5
Worry (Nagel 2018)	0.3	0.5	2.8	-1.0	-1.7	0.4	-0.2	-0.2	-0.2	-0.4	1.0	-0.3	0.8	0.0	1.0	0.0	-1.4	-0.4	0.4	-0.4
Rheumatoid Arthritis	0.3	0.4	1.1	0.8	0.0	-0.5	-0.5	-0.6	-1.0	-0.5	1.0	-0.5	-0.3	-0.6	-0.2	-0.9	0.5	-0.5	-0.2	-0.5
Hypothyroidism (self reported)	0.3	0.7	2.7	0.6	0.2	-0.8	-1.0	-0.9	0.1	-1.0	0.2	-0.9	-0.6	-0.8	-0.4	-1.6	-0.9	-1.1	-0.6	-1.0
Average weekly spirits intake	0.3	0.4	0.7	0.8	-0.3	-0.6	-0.8	-0.9	0.6	-0.8	0.4	-0.7	-0.6	-0.8	-0.5	-0.3	-0.3	-0.9	-0.6	-0.8
Systolic blood pressure, automated reading	0.3	0.8	4.0	1.5	-0.4	-0.3	0.6	0.4	0.4	0.7	2.0	0.6	1.2	0.3	0.2	-0.7	1.4	0.6	0.5	0.7
Diabetes (father)	0.3	0.4	4.4	2.1	0.0	-0.8	-0.2	-0.5	-0.6	-0.2	0.7	-0.1	-0.4	-0.5	-0.6	-0.3	0.4	-0.2	-0.1	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	2.4	-1.5	0.1	-0.1	-0.0	0.0	-0.3	-0.1	-0.5	-0.1	-0.5	0.3	0.1	0.9	-1.5	-0.0	0.0	-0.1
Hearing difficulty/problems with background noise	0.3	0.6	3.4	-1.8	-0.5	0.6	-0.0	0.4	-1.0	-0.0	0.0	-0.1	0.3	0.3	0.8	1.1	-1.3	-0.0	0.7	-0.0
Medication: Ramipril	0.3	0.3	1.2	-0.4	0.5	0.1	0.4	0.5	0.0	0.4	-0.6	0.6	0.7	0.7	0.8	-1.1	-0.3	0.5	-0.5	0.5
Alcohol intake versus 10 years previously	0.3	0.5	3.3	0.4	0.7	-0.0	-0.4	-0.3	-0.6	-0.4	-0.8	-0.2	-1.3	-0.3	-0.5	-1.0	1.8	-0.4	-0.4	-0.4
Worrier / anxious feelings	0.3	0.5	2.1	-0.6	-1.5	0.2	0.1	0.0	-1.1	0.0	0.6	-0.0	1.3	0.2	0.9	0.7	-0.9	0.0	0.6	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.3	-1.2	0.3	0.1	-0.3	-0.0	-0.9	-0.2	-0.6	-0.4	-1.0	0.1	0.5	-0.2	-1.1	-0.2	-0.3	-0.2
Ever highly irritable/argumentative for 2 days	0.3	0.4	3.0	1.0	-0.2	-0.2	0.4	0.1	-0.1	0.3	0.6	0.4	-0.2	0.2	-0.5	1.0	1.7	0.4	0.3	0.3
Arm fat-free mass (right)	0.3	1.5	3.8	1.0	0.5	-1.2	-1.3	-1.2	-1.9	-1.2	-1.0	-1.3	-1.4	-1.1	-0.6	-1.8	-0.3	-1.3	-1.1	-1.2
Comparative body size at age 10	0.3	0.8	7.6	-0.5	-1.8	0.4	-0.1	-0.3	0.2	-0.2	0.3	-0.2	-0.4	-0.3	0.8	1.2	-2.8	-0.1	0.3	-0.2
Heart disease (mother)	0.3	0.4	2.6	0.8	-0.2	0.0	0.1	0.1	0.9	0.1	1.6	0.1	1.2	-0.2	-0.4	0.5	0.5	0.1	0.3	0.1
Arm predicted mass (right)	0.3	1.6	4.2	1.0	0.6	-1.3	-1.4	-1.2	-2.0	-1.3	-1.0	-1.4	-1.4	-1.2	-0.8	-1.8	-0.1	-1.4	-1.1	-1.3
Suffer from ‘nerves’	0.3	0.4	1.6	-0.6	-0.4	0.2	0.3	0.4	1.1	0.3	-0.4	0.3	1.1	0.6	1.2	-0.7	-1.3	0.3	-0.0	0.3
Family relationship satisfaction	0.3	0.4	0.9	-0.3	0.1	-0.3	-0.6	-0.6	0.9	-0.6	-0.2	-0.6	0.1	-0.6	-1.0	0.8	-0.8	-0.6	-0.5	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	2.1	1.0	-1.4	0.0	0.5	0.2	0.8	0.5	0.6	0.5	-0.4	0.3	0.6	-0.5	0.5	0.4	0.7	0.5
Smoking status: Previous	0.3	0.5	2.2	0.8	0.0	-0.6	-0.2	-0.3	1.4	-0.1	-0.2	-0.1	1.0	-0.3	0.0	-1.1	-1.5	-0.1	-0.8	-0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	1.9	-0.1	0.5	-0.1	-0.1	-0.0	1.0	-0.1	-0.9	-0.1	-1.4	-0.2	-0.5	0.1	1.4	-0.1	-0.2	-0.1
Hearing aid user	0.3	0.3	1.9	1.4	-0.1	-0.5	0.3	0.1	-0.0	0.2	0.5	0.4	-0.2	0.0	-0.6	0.6	1.4	0.3	0.5	0.2
Financial situation satisfaction	0.3	0.4	0.9	0.1	0.3	0.3	0.8	0.7	0.7	1.0	-0.2	1.0	0.5	0.8	-0.0	0.3	-0.1	1.0	0.4	1.0
Medication: Bendroflumethiazide	0.3	0.5	2.5	-0.6	-0.8	0.6	0.3	0.3	0.7	0.3	1.6	0.3	0.9	0.4	0.7	0.9	-1.0	0.4	0.3	0.3
Medication: Paracetamol	0.3	0.4	1.8	0.1	-0.0	-0.3	-0.5	-0.5	0.0	-0.5	-1.2	-0.6	-1.3	-0.6	-0.6	1.0	-0.5	-0.5	-0.3	-0.5
Medication: Lisinopril	0.3	0.4	1.8	0.3	-0.8	0.6	0.5	0.5	0.7	0.4	0.7	0.5	0.8	0.1	0.2	1.3	0.3	0.6	0.5	0.4
Number of operations (self-reported)	0.3	0.4	2.6	-1.1	0.3	-0.1	-0.7	-0.5	-0.4	-0.6	0.1	-0.7	0.2	-0.3	-0.1	-0.1	-1.6	-0.6	-0.9	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.9	1.1	-0.6	0.0	0.6	0.4	0.6	0.6	0.6	0.7	0.4	0.2	0.5	-0.4	1.4	0.6	0.6	0.6
Depression (Nagel 2018)	0.2	0.3	1.8	-1.3	0.2	-0.2	0.2	0.2	-0.1	0.1	-0.8	0.1	-0.2	0.4	0.3	0.8	-1.3	0.2	0.2	0.1
Schizophrenia (2018)	0.2	0.5	1.3	-1.0	-0.8	0.4	-0.7	-0.7	-1.2	-0.9	-0.4	-0.8	-0.1	-0.6	-0.4	0.6	-0.0	-0.8	0.1	-0.9
Reaction Time	0.2	0.3	1.7	-0.8	-0.5	-0.1	-0.2	-0.2	-0.3	-0.2	-0.8	-0.3	0.9	-0.2	-0.4	1.1	-1.3	-0.2	-0.2	-0.2
Crohns Disease (2012)	0.2	0.3	1.2	0.1	0.9	-0.4	-0.2	-0.3	0.9	-0.1	-1.0	-0.2	-0.1	-0.2	-0.4	-0.3	-1.1	-0.1	-0.5	-0.1
Schizophrenia (2014)	0.2	0.3	1.6	-1.0	-1.3	0.7	0.1	0.0	-0.3	-0.1	0.7	-0.0	0.7	-0.1	0.4	0.7	0.5	-0.1	0.8	-0.2
BMI	0.2	1.2	4.3	-0.8	-1.5	-0.1	-1.0	-1.0	-1.3	-1.0	-0.5	-1.2	-1.5	-1.0	0.6	-0.6	-2.1	-1.1	-0.3	-1.0
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.9	0.6	-0.9	0.2	0.5	0.3	0.6	0.5	0.3	0.6	0.9	0.3	0.7	-0.1	0.3	0.5	0.7	0.5
Hair Pigment	0.2	4.5	7.1	-0.4	1.8	-1.8	-2.6	-2.5	-1.8	-2.6	-1.6	-2.7	-1.4	-2.2	-1.4	-1.9	-2.4	-2.5	-2.4	-2.6
Angina	0.2	0.3	1.7	0.5	0.1	0.2	0.5	0.4	0.9	0.5	-0.7	0.5	1.3	0.3	-0.0	0.1	0.1	0.6	-0.3	0.5
Medication: Metformin	0.2	0.3	2.1	0.4	-0.6	-0.2	-0.0	-0.2	1.5	0.0	-1.0	0.0	0.4	-0.1	0.5	-0.8	-1.0	-0.0	0.1	0.1
Severe depression (siblings)	0.2	0.3	1.1	-0.4	-0.8	0.2	-0.5	-0.4	0.1	-0.6	0.3	-0.6	-0.7	-0.3	0.4	-0.5	-1.1	-0.6	0.1	-0.6
Body mass index (BMI)	0.2	0.7	2.6	-1.2	-0.6	0.3	-0.6	-0.5	-1.5	-0.6	-0.4	-0.7	-0.7	-0.3	0.9	-1.4	-1.6	-0.7	-0.4	-0.6
Past tobacco smoking	0.2	0.3	1.6	-1.0	0.0	0.5	0.1	0.2	-0.5	-0.0	-0.3	-0.0	-1.0	0.3	0.0	1.3	0.8	-0.1	0.4	0.0
Had other major operations	0.2	0.2	1.0	-0.7	0.2	0.1	-0.4	-0.3	-0.3	-0.5	0.3	-0.5	-0.5	-0.4	-0.4	0.8	1.0	-0.5	-0.1	-0.5
Diabetes (self-reported)	0.2	0.4	1.5	0.4	-0.7	-0.0	0.4	0.2	1.2	0.4	-0.7	0.4	1.1	0.3	0.8	-0.6	-0.6	0.4	0.3	0.4
Neuroticism score	0.2	0.4	1.3	-0.2	0.3	-0.6	-0.8	-0.6	-0.8	-0.8	-0.1	-0.8	0.4	-0.4	-0.3	-0.7	-1.1	-0.8	-0.8	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.2	0.4	-0.4	-0.8	-0.4	-0.5	-0.5	-0.4	-1.1	-0.4	-0.2	-0.4	-0.6	1.0	-0.9	-0.4	-0.4	-0.4
Medication: Lansoprazole	0.2	0.2	1.2	1.1	-0.7	-0.1	0.0	-0.1	-0.3	-0.0	0.2	0.1	0.3	-0.4	-0.4	1.0	0.4	0.1	-0.0	-0.1
Wheeze or whistling in the chest in last year	0.2	0.4	1.5	-1.2	-1.0	1.0	0.1	0.2	-0.3	0.1	-0.4	0.1	1.2	0.2	0.7	-0.0	-0.8	0.1	0.2	0.0
Age at first live birth	0.2	0.4	1.8	-0.3	-0.7	-0.1	-0.4	-0.4	1.3	-0.4	-0.3	-0.6	-0.1	-0.4	0.2	0.7	-1.4	-0.5	0.1	-0.4
Angina (self-reported)	0.2	0.3	1.3	0.5	0.2	0.3	0.5	0.5	1.1	0.5	-0.6	0.5	1.1	0.4	-0.0	0.1	0.0	0.6	-0.3	0.5
Pulse rate, automated reading	0.2	0.7	1.7	0.0	-0.4	0.9	0.8	0.7	1.1	0.8	1.2	1.0	0.3	1.0	1.2	-1.3	0.1	0.8	0.2	0.8
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.3	-0.1	-0.5	0.3	0.4	0.3	-0.1	0.3	0.9	0.4	1.1	0.5	0.5	0.3	0.5	0.4	1.0	0.3
Whole body fat-free mass	0.2	1.2	3.7	1.0	0.6	-1.1	-1.1	-1.0	-1.9	-1.1	-1.0	-1.1	-1.0	-0.9	-0.5	-1.9	-0.3	-1.1	-1.0	-1.1
Loneliness, isolation	0.2	0.3	1.3	-0.7	0.5	0.3	0.4	0.6	-0.9	0.5	0.1	0.5	1.1	0.6	-0.1	0.6	0.6	0.5	0.2	0.5
Ever had bowel cancer screening	0.2	0.3	1.6	0.3	0.3	0.5	0.2	0.1	-0.5	0.2	1.3	0.2	0.7	0.2	0.4	-0.8	0.6	0.2	0.2	0.2
Diabetes diagnosed by doctor	0.2	0.4	1.3	0.7	-0.7	-0.4	0.2	0.0	1.1	0.2	-0.4	0.2	1.1	0.0	0.7	-1.1	-0.7	0.2	0.2	0.3
Medication: Gliclazide	0.2	0.2	0.6	0.5	0.3	-0.7	-0.4	-0.5	0.1	-0.4	-0.1	-0.4	-0.1	-0.6	-0.6	0.8	0.2	-0.4	-0.4	-0.4
Smoking status: Current	0.2	0.3	2.4	0.5	0.6	0.1	0.1	0.2	-0.8	0.1	0.1	0.1	-0.4	-0.0	-0.6	0.4	1.5	0.1	0.3	0.1
Whole body water mass	0.2	1.1	3.5	1.0	0.6	-1.1	-1.1	-0.9	-1.8	-1.1	-0.9	-1.0	-0.9	-0.9	-0.5	-1.9	-0.2	-1.1	-1.0	-1.1
Guilty feelings	0.2	0.2	2.4	-1.5	0.9	0.3	0.0	0.4	-0.0	0.0	0.0	0.0	-0.1	0.4	0.3	-0.2	-0.7	0.0	-0.0	0.0
Eye problems/disorders: Glaucoma	0.2	0.3	1.6	1.1	0.2	-0.1	0.3	0.2	-0.2	0.3	0.4	0.4	0.9	0.1	-0.5	-0.3	1.3	0.3	-0.2	0.3
Ever smoked	0.2	0.3	1.3	0.9	-0.4	-0.0	0.2	0.1	0.6	0.2	1.1	0.2	1.1	-0.0	0.4	-1.0	-0.8	0.3	0.2	0.2
Ever had prostate specific antigen (PSA) test	0.2	0.2	2.2	-0.3	0.8	0.7	-0.0	0.4	0.4	0.0	0.4	0.1	-0.1	-0.0	-0.2	-0.6	1.5	0.0	-0.2	0.0
Arm predicted mass (left)	0.2	1.1	4.2	1.0	0.5	-1.0	-1.0	-0.9	-1.9	-1.0	-0.8	-1.0	-1.3	-0.9	-0.3	-2.0	0.1	-1.0	-0.8	-1.0
Schizophrenia vs Biploar Disorder	0.1	0.2	0.8	0.9	-0.3	0.2	-0.1	-0.4	0.0	-0.2	0.7	-0.0	0.5	-0.3	-0.3	-0.9	-0.3	-0.2	-0.1	-0.3
Crohns Disease (2017)	0.1	0.3	1.1	0.2	0.8	-0.5	-0.5	-0.5	0.0	-0.6	-0.6	-0.5	-0.2	-0.5	-0.4	-1.1	-0.5	-0.5	-0.7	-0.6
Irritable Bowel Disease (IBD)	0.1	0.2	1.0	-0.4	1.0	-0.0	-0.1	0.0	-0.5	-0.1	-0.2	0.1	-0.5	0.3	0.1	-0.9	-0.3	-0.0	-0.2	-0.2
Ulcerative Colitis (UC)	0.1	0.2	0.8	-0.6	0.7	0.2	0.4	0.3	-0.6	0.3	0.2	0.5	-0.4	0.9	0.6	-0.6	-0.4	0.4	0.2	0.3
Body Mass Index (BMI) (2010)	0.1	0.2	0.7	-0.7	-0.8	0.2	-0.4	-0.3	0.3	-0.4	-0.4	-0.5	-0.4	-0.2	0.1	0.7	-0.6	-0.4	-0.0	-0.4
Blood Eosinophil Count	0.1	1.1	3.3	-0.9	-1.6	1.2	1.0	1.0	0.1	1.1	-0.3	0.9	1.0	0.7	0.5	1.8	0.5	1.0	1.2	1.1
Blood Platelet Count	0.1	0.9	1.8	-0.9	0.9	-0.4	-1.2	-1.0	-1.2	-1.3	0.3	-1.4	-0.9	-1.1	-0.3	-0.6	0.4	-1.4	-0.6	-1.2
Waist Hip Ratio (WHR)	0.1	0.4	4.0	-0.5	-0.4	0.6	0.2	0.2	-0.4	0.1	0.5	0.1	-0.9	0.0	0.2	0.2	2.0	0.0	0.8	0.1
Smoking Status	0.1	0.2	0.8	0.9	0.8	-0.3	-0.2	-0.2	-0.3	-0.1	0.1	-0.1	0.3	-0.5	-0.7	-0.1	0.3	-0.1	-0.3	-0.1
Lung FVC	0.1	0.3	1.6	-0.7	0.2	0.5	-0.2	-0.2	0.6	-0.3	1.3	-0.2	-0.0	-0.1	-0.4	0.9	0.8	-0.2	0.5	-0.3
Medication: Co-codamol	0.1	0.1	1.1	-0.0	-0.1	-0.1	-0.1	0.0	-0.4	-0.1	0.2	-0.1	1.0	-0.0	0.2	0.3	-0.2	-0.1	0.4	-0.0
Current tobacco smoking	0.1	0.2	1.2	0.5	0.7	-0.0	0.1	0.1	-0.6	0.1	-0.2	0.2	-0.5	-0.0	-0.6	0.3	1.1	0.2	0.1	0.2
Medication: Levothyroxine sodium	0.1	0.2	2.2	-0.2	0.2	0.1	-0.2	0.0	0.4	-0.3	0.6	-0.0	-0.2	0.0	0.3	-1.5	-0.1	-0.3	-0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.4	-0.3	-0.1	0.4	0.3	0.3	-0.4	0.4	-0.3	0.4	0.7	0.3	0.3	-0.6	0.2	0.4	0.2	0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.5	-0.4	-0.3	0.2	-0.0	-0.0	0.2	-0.1	-0.7	-0.0	0.6	0.2	0.1	-0.1	-0.6	0.0	-0.0	-0.1
Financial difficulties in last 2 years	0.1	0.1	0.8	-0.5	-0.1	-0.1	-0.1	-0.0	-0.3	-0.1	0.2	-0.1	0.1	0.0	-0.5	0.9	-0.4	-0.0	-0.3	-0.1
Trunk fat-free mass	0.1	0.6	4.2	1.0	0.4	-0.6	-0.5	-0.4	-1.5	-0.5	-0.2	-0.4	-0.6	-0.3	-0.0	-2.0	0.6	-0.5	-0.5	-0.6
Prospective memory result	0.1	0.1	0.6	-0.3	0.2	0.4	-0.0	-0.0	0.5	-0.0	0.8	0.0	0.2	0.0	-0.3	0.1	0.8	-0.0	0.1	-0.1
Lung cancer (father)	0.1	0.2	1.0	0.5	-0.4	-0.4	0.0	-0.0	-1.0	0.0	0.1	0.0	0.0	0.1	0.3	-0.9	-0.1	-0.0	0.5	0.0
Trunk predicted mass	0.1	0.6	4.0	1.0	0.4	-0.6	-0.5	-0.4	-1.4	-0.5	-0.3	-0.5	-0.6	-0.4	-0.1	-2.0	0.6	-0.5	-0.5	-0.6
Birth weight of first child	0.1	0.2	1.5	-0.3	-0.2	0.0	-0.2	-0.0	-0.0	-0.1	0.9	-0.3	-1.2	-0.0	0.5	0.1	-0.5	-0.2	0.3	-0.1
Exposure to tobacco smoke outside home	0.1	0.1	1.6	0.0	-0.0	0.3	0.0	0.3	0.1	-0.1	0.3	0.0	0.7	0.1	-0.3	0.0	1.3	-0.0	0.0	-0.1
Health satisfaction	0.1	0.2	0.9	-1.0	-0.2	0.5	-0.0	0.1	-0.6	0.0	-0.6	-0.0	-0.1	0.4	0.2	-0.8	-0.4	-0.1	-0.3	0.0
Medication for pain relief, constipation, heartburn	0.1	0.2	1.2	-0.6	0.2	0.0	-0.4	-0.3	-1.1	-0.4	1.0	-0.4	0.0	-0.2	0.2	-0.2	-0.1	-0.5	0.1	-0.4
Alcohol intake frequency.	0.1	0.3	1.8	0.3	-0.1	-0.4	-0.2	-0.3	-0.4	-0.3	-1.4	-0.3	-1.3	-0.3	-0.7	0.6	0.0	-0.3	-0.4	-0.3
Mood swings	0.1	0.2	0.7	0.4	0.7	-0.8	-0.3	-0.3	-0.1	-0.3	-0.5	-0.3	-0.6	-0.1	-0.8	-0.3	0.2	-0.4	-0.5	-0.3
Miserableness	0.1	0.2	1.4	-0.4	1.0	-0.2	0.0	0.3	-0.4	0.1	-1.2	0.1	-0.1	0.4	-0.0	-0.3	-0.4	0.1	-0.7	0.2
Commuting to job workplace: Public transport	0.1	0.1	0.4	-0.0	-0.4	0.2	-0.1	-0.0	-0.2	-0.2	0.1	-0.2	0.5	-0.2	0.1	-0.6	0.5	-0.1	0.2	-0.2
Arm fat-free mass (left)	0.1	0.7	3.2	0.7	0.2	-0.7	-0.7	-0.6	-1.6	-0.7	-0.7	-0.7	-0.8	-0.5	0.0	-1.8	0.2	-0.7	-0.5	-0.7
Ever depressed for a whole week	0.1	0.1	1.1	-0.3	-1.0	0.6	-0.1	-0.3	0.0	-0.3	-0.2	-0.2	-0.3	0.0	0.2	-0.3	0.1	-0.3	0.1	-0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.4	1.8	-0.2	0.1	0.1	0.6	0.6	0.6	0.7	-0.1	0.5	0.8	0.3	-0.5	1.4	0.7	0.6	0.3	0.7
Tanning	0.0	0.4	1.3	-0.7	0.6	0.5	0.6	0.6	1.1	0.6	-1.0	0.6	-0.3	0.4	-0.2	0.7	0.9	0.7	-0.3	0.6

Hub : Genes

FRK

Models

Trait associations