Best TWAS P=1.25e-07 · Best GWAS P=2.01e-07 conditioned to 0.267
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | TEX10 | 0.27 | 0.27 | lasso | 8 | 0.28 | 7e-23 | -5.2 | -5.1 | 2.8e-07 | 1.00 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | INVS | 0.10 | 0.03 | blup | 107 | 0.07 | 4e-04 | -4.9 | -5.3 | 1.2e-07 | 0.89 | 0.02 | 0.94 | TRUE |