[Hub]/) : Traits : Impedance of arm (left) :

chr9:93,630,445-97,136,378

Best TWAS P=2.45e-23 · Best GWAS P=2.02e-23 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPP 0.43 0.52 bslmm 525 0.51 2.3e-72 -5.4 -5.4 5.8e-08 0.65 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100128361 0.10 0.08 lasso 4 0.09 2.2e-11 -5.4 -5.5 3.7e-08 0.71 0.99 0.01 FALSE
3 CommonMind Brain Pre-frontal Cortex OGN 0.04 0.04 lasso 4 0.04 2.3e-05 -4.9 -6.6 4.5e-11 0.68 0.34 0.60 FALSE
4 GTEx Adipose Subcutaneous ANKRD19P 0.06 0.03 enet 16 0.04 2.2e-04 -2.9 5.8 8.3e-09 -0.71 0.25 0.72 FALSE
5 GTEx Adipose Visceral Omentum CENPP 0.28 0.29 enet 14 0.30 5.1e-16 -5.0 -5.2 2.6e-07 0.63 1.00 0.00 FALSE
6 GTEx Adrenal Gland CENPP 0.45 0.32 enet 21 0.31 7.5e-12 -5.4 -5.2 1.7e-07 0.63 1.00 0.00 FALSE
7 GTEx Artery Aorta NOL8 0.09 0.04 lasso 9 0.02 2.3e-02 -9.1 8.6 8.8e-18 -0.89 0.05 0.93 FALSE
8 GTEx Artery Tibial NOL8 0.04 0.03 lasso 4 0.03 3.5e-03 -10.0 9.6 7.1e-22 -0.99 0.02 0.95 FALSE
9 GTEx Brain Cerebellar Hemisphere IPPK 0.17 0.22 lasso 13 0.16 6.8e-05 -9.4 -9.2 4.3e-20 0.94 0.09 0.87 FALSE
10 GTEx Brain Cerebellum IPPK 0.12 0.01 enet 17 0.01 1.6e-01 -8.0 -6.4 1.4e-10 0.81 0.07 0.53 FALSE
11 GTEx Brain Cerebellum CENPP 0.41 0.34 lasso 6 0.32 2.5e-10 -5.0 -5.2 2.2e-07 0.64 0.98 0.01 FALSE
12 GTEx Brain Cortex CENPP 0.24 0.29 lasso 9 0.28 2.1e-08 -4.9 -5.2 2.5e-07 0.65 0.29 0.70 FALSE
13 GTEx Brain Frontal Cortex BA9 CENPP 0.47 0.30 lasso 9 0.29 1.8e-08 -4.9 -5.3 1.3e-07 0.61 0.77 0.10 FALSE
14 GTEx Brain Hypothalamus CENPP 0.35 0.22 lasso 6 0.14 4.0e-04 -5.0 -5.4 8.0e-08 0.64 0.32 0.31 FALSE
15 GTEx Cells Transformed fibroblasts OGN 0.03 0.03 lasso 2 0.01 3.2e-02 -8.8 -8.8 1.1e-18 0.84 0.11 0.83 FALSE
16 GTEx Cells Transformed fibroblasts PHF2 0.07 0.06 lasso 5 0.04 5.5e-04 -7.5 -7.4 9.9e-14 0.08 0.01 0.99 TRUE
17 GTEx Colon Sigmoid CENPP 0.55 0.40 lasso 5 0.39 8.8e-15 -5.4 -5.4 8.0e-08 0.63 1.00 0.00 FALSE
18 GTEx Colon Transverse CENPP 0.25 0.26 lasso 2 0.24 1.5e-11 -5.4 -5.4 8.0e-08 0.64 1.00 0.00 FALSE
19 GTEx Esophagus Gastroesophageal Junction CENPP 0.22 0.19 lasso 8 0.15 6.2e-06 -5.4 -6.0 2.1e-09 0.70 0.54 0.44 FALSE
20 GTEx Esophagus Muscularis OGN 0.07 0.03 enet 13 0.02 2.0e-02 -2.1 -5.6 2.3e-08 0.60 0.07 0.85 FALSE
21 GTEx Esophagus Muscularis CENPP 0.40 0.40 lasso 5 0.41 2.7e-26 -5.4 -5.2 1.7e-07 0.64 1.00 0.00 FALSE
22 GTEx Heart Atrial Appendage CENPP 0.41 0.40 lasso 7 0.40 1.7e-19 -4.9 -5.2 2.1e-07 0.61 1.00 0.00 FALSE
23 GTEx Liver OGN 0.13 0.03 lasso 4 0.04 3.5e-02 -4.6 -6.9 4.0e-12 0.63 0.05 0.73 FALSE
24 GTEx Liver ECM2 0.16 0.18 enet 8 0.18 7.4e-06 -8.6 8.6 9.2e-18 -0.85 0.16 0.82 FALSE
25 GTEx Liver CENPP 0.44 0.21 lasso 9 0.21 2.0e-06 -6.0 -5.9 4.7e-09 0.72 0.75 0.08 FALSE
26 GTEx Lung CENPP 0.30 0.24 lasso 8 0.27 1.1e-20 -5.4 -5.5 3.4e-08 0.62 1.00 0.00 FALSE
27 GTEx Lung NOL8 0.08 0.03 enet 15 0.04 2.3e-04 -8.0 7.5 5.8e-14 -0.88 0.03 0.97 FALSE
28 GTEx Muscle Skeletal OGN 0.03 0.02 enet 9 0.03 3.0e-04 -9.0 -9.1 1.3e-19 0.90 0.05 0.92 FALSE
29 GTEx Muscle Skeletal CENPP 0.30 0.29 lasso 6 0.30 1.0e-29 -5.4 -5.4 8.6e-08 0.65 1.00 0.00 FALSE
30 GTEx Nerve Tibial OGN 0.08 0.14 lasso 9 0.12 6.3e-09 -9.7 -9.6 5.8e-22 0.93 0.08 0.92 FALSE
31 GTEx Nerve Tibial CENPP 0.47 0.36 enet 45 0.39 7.6e-29 -5.0 -5.7 1.4e-08 0.61 1.00 0.00 FALSE
32 GTEx Nerve Tibial NOL8 0.10 0.02 enet 7 0.03 4.7e-03 -8.6 8.9 3.7e-19 -0.89 0.13 0.82 FALSE
33 GTEx Pituitary IPPK 0.16 0.07 lasso 4 0.07 8.5e-03 -7.7 -8.6 7.5e-18 0.85 0.10 0.58 FALSE
34 GTEx Pituitary CENPP 0.38 0.31 lasso 8 0.34 2.9e-09 -4.9 -5.2 1.5e-07 0.66 0.32 0.65 FALSE
35 GTEx Skin Sun Exposed Lower leg CENPP 0.20 0.06 lasso 9 0.14 2.9e-11 3.1 -5.7 1.5e-08 0.56 0.97 0.03 FALSE
36 GTEx Small Intestine Terminal Ileum CENPP 0.29 0.11 enet 11 0.10 2.9e-03 -8.2 -7.0 1.9e-12 0.71 0.17 0.45 FALSE
37 GTEx Spleen NOL8 0.29 0.24 lasso 2 0.19 1.1e-05 -7.6 7.6 2.8e-14 -0.74 0.16 0.77 FALSE
38 GTEx Stomach CENPP 0.28 0.24 lasso 6 0.22 5.0e-11 -5.4 -5.2 2.0e-07 0.61 0.98 0.02 FALSE
39 GTEx Testis NOL8 0.19 0.24 lasso 11 0.23 1.3e-10 -10.0 10.0 2.4e-23 -0.99 0.02 0.98 TRUE
40 GTEx Thyroid OGN 0.09 0.08 lasso 4 0.05 9.9e-05 -6.8 -7.5 8.2e-14 0.65 0.22 0.77 FALSE
41 GTEx Whole Blood NOL8 0.05 0.01 enet 21 0.01 3.5e-02 -9.3 7.6 2.5e-14 -0.69 0.04 0.87 FALSE
42 METSIM Adipose NOL8 0.06 0.03 blup 418 0.04 4.1e-07 -6.0 8.2 3.4e-16 -0.82 0.03 0.97 FALSE
43 METSIM Adipose ROR2 0.12 0.04 bslmm 639 0.05 3.2e-08 3.2 5.5 3.5e-08 -0.28 1.00 0.00 FALSE
44 NTR Blood ASPN 0.03 0.04 lasso 8 0.03 3.4e-11 -5.4 -5.7 1.0e-08 0.66 1.00 0.00 FALSE
45 NTR Blood CENPP 0.02 0.02 lasso 4 0.02 2.0e-07 -5.4 -7.8 9.0e-15 0.82 0.44 0.56 FALSE
46 NTR Blood IPPK 0.02 0.01 bslmm 416 0.01 9.9e-06 -8.8 -8.3 1.6e-16 0.79 0.29 0.70 FALSE
47 NTR Blood OGN 0.10 0.11 lasso 3 0.11 5.1e-33 -5.4 -5.4 7.7e-08 0.64 1.00 0.00 FALSE
48 YFS Blood NOL8 0.06 0.09 lasso 17 0.10 1.5e-29 -9.7 8.8 1.2e-18 -0.94 0.01 0.99 FALSE
49 The Cancer Genome Atlas Breast Invasive Carcinoma CENPP 0.07 0.03 lasso 5 0.06 2.1e-11 3.1 -6.7 2.8e-11 0.58 0.99 0.01 FALSE
50 The Cancer Genome Atlas Breast Invasive Carcinoma ECM2 0.03 0.02 lasso 5 0.02 3.9e-05 5.0 -7.1 8.9e-13 0.81 0.02 0.97 FALSE
51 The Cancer Genome Atlas Breast Invasive Carcinoma OGN 0.02 0.02 lasso 1 0.02 2.7e-04 -9.7 -9.7 2.5e-22 0.94 0.05 0.93 FALSE
52 The Cancer Genome Atlas Breast Invasive Carcinoma PHF2 0.02 0.01 blup 104 0.01 4.6e-03 -7.7 -7.0 2.1e-12 0.09 0.00 0.98 FALSE
53 The Cancer Genome Atlas Esophageal Carcinoma PHF2 0.29 0.14 blup 103 0.16 1.0e-05 -6.8 -6.7 2.5e-11 0.05 0.05 0.90 FALSE
54 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CENPP 0.06 0.02 blup 160 0.04 6.3e-05 3.1 -6.1 1.4e-09 0.51 0.53 0.05 FALSE
55 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma OGN 0.02 0.01 blup 51 0.01 3.4e-02 -7.8 -8.9 5.8e-19 0.85 0.05 0.33 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CENPP 0.23 0.16 lasso 8 0.16 1.3e-17 -5.4 -5.7 1.5e-08 0.65 1.00 0.00 FALSE
57 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CENPP 0.23 0.16 lasso 6 0.16 1.9e-09 -5.4 -5.3 9.1e-08 0.64 0.99 0.00 FALSE
58 The Cancer Genome Atlas Brain Lower Grade Glioma CENPP 0.33 0.28 lasso 8 0.28 1.6e-31 -5.4 -5.4 8.8e-08 0.66 1.00 0.00 FALSE
59 The Cancer Genome Atlas Liver Hepatocellular Carcinoma OGN 0.07 0.08 lasso 1 0.06 8.0e-04 -9.2 -9.2 4.0e-20 0.89 0.04 0.84 FALSE
60 The Cancer Genome Atlas Lung Adenocarcinoma CENPP 0.14 0.08 lasso 5 0.07 2.9e-08 -5.4 -5.4 8.1e-08 0.60 1.00 0.00 FALSE
61 The Cancer Genome Atlas Lung Adenocarcinoma OGN 0.07 0.12 blup 52 0.14 1.2e-15 -9.2 -9.5 2.0e-21 0.94 0.13 0.87 FALSE
62 The Cancer Genome Atlas Lung Adenocarcinoma OMD 0.04 0.06 lasso 3 0.05 1.1e-06 -9.2 -9.2 5.3e-20 0.89 0.15 0.85 FALSE
63 The Cancer Genome Atlas Lung Adenocarcinoma PHF2 0.07 0.03 blup 104 0.05 1.9e-06 -6.8 -5.7 1.1e-08 -0.02 0.16 0.81 FALSE
64 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CENPP 0.06 0.04 blup 160 0.05 5.6e-06 3.1 -6.9 3.8e-12 0.62 0.73 0.10 FALSE
65 The Cancer Genome Atlas Lung Squamous Cell Carcinoma OGN 0.02 0.02 blup 52 0.02 2.8e-03 7.7 -9.6 6.5e-22 0.92 0.06 0.82 FALSE
66 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CENPP 0.10 0.01 blup 161 0.04 6.3e-04 -2.3 -5.7 1.1e-08 0.51 0.26 0.10 FALSE
67 The Cancer Genome Atlas Pancreatic Adenocarcinoma C9orf44 0.27 0.05 lasso 6 0.10 7.4e-05 -6.0 5.6 1.9e-08 -0.50 0.13 0.16 FALSE
68 The Cancer Genome Atlas Pancreatic Adenocarcinoma OGN 0.05 0.02 blup 52 0.03 2.4e-02 7.7 -9.6 5.5e-22 0.92 0.03 0.65 FALSE
69 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CENPP 0.14 0.04 lasso 12 0.03 1.9e-02 -5.4 -5.6 2.8e-08 0.69 0.11 0.36 FALSE
70 The Cancer Genome Atlas Prostate Adenocarcinoma CENPP 0.29 0.19 lasso 13 0.19 4.5e-19 -5.0 -6.2 4.9e-10 0.72 1.00 0.00 FALSE
71 The Cancer Genome Atlas Prostate Adenocarcinoma OGN 0.16 0.01 enet 16 0.05 5.8e-06 -9.4 -5.2 2.5e-07 0.52 0.04 0.51 FALSE
72 The Cancer Genome Atlas Thyroid Carcinoma CENPP 0.22 0.15 blup 158 0.19 3.3e-18 -4.5 -5.6 2.0e-08 0.62 1.00 0.00 FALSE
73 The Cancer Genome Atlas Thyroid Carcinoma IPPK 0.03 0.04 blup 50 0.04 6.7e-05 4.6 -5.9 3.6e-09 0.51 0.69 0.04 FALSE
74 The Cancer Genome Atlas Thyroid Carcinoma NOL8 0.02 0.01 blup 38 0.02 7.3e-03 -7.9 9.8 8.0e-23 -0.94 0.02 0.74 FALSE