Best TWAS P=5.85e-08 · Best GWAS P=7.58e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | HSD17B12 | 0.50 | 0.41 | enet | 33 | 0.29 | 3.0e-08 | -4.5 | 5.3 | 1.1e-07 | -0.89 | 0.02 | 0.95 | FALSE |
2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | HSD17B12 | 0.18 | 0.22 | lasso | 2 | 0.20 | 2.2e-10 | -4.9 | 5.4 | 5.9e-08 | -0.99 | 0.00 | 0.99 | TRUE |