Best TWAS P=3.93e-08 · Best GWAS P=2.62e-05 conditioned to 0.000298
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | SNX29 | 0.22 | 0.04 | enet | 22 | 0.06 | 2.2e-05 | 3.3 | 5.2 | 1.6e-07 | 0.28 | 0.04 | 0.53 | FALSE |
2 | GTEx | Thyroid | SNX29 | 0.36 | 0.14 | lasso | 10 | 0.20 | 6.6e-15 | 3.8 | 5.2 | 2.3e-07 | 0.48 | 0.03 | 0.62 | FALSE |
3 | ROSMAP | Brain Pre-frontal Cortex | SNX29 | 0.11 | 0.05 | lasso | 8 | 0.06 | 3.2e-08 | 3.9 | 5.2 | 2.3e-07 | 0.48 | 0.03 | 0.60 | FALSE |
4 | The Cancer Genome Atlas | Lung Adenocarcinoma | SNX29 | 0.10 | 0.02 | enet | 18 | 0.04 | 2.3e-05 | 3.2 | 5.5 | 3.9e-08 | 0.11 | 0.04 | 0.19 | TRUE |