Best TWAS P=3.19e-08 · Best GWAS P=3.11e-08 conditioned to 0.0538
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | ACTR1B | 0.42 | 0.19 | enet | 11 | 0.23 | 2.3e-16 | -4.4 | -5.5 | 3.2e-08 | 0.78 | 0.16 | 0.81 | TRUE |
| 2 | GTEx | Whole Blood | ACTR1B | 0.09 | 0.04 | lasso | 3 | 0.04 | 1.7e-04 | -4.4 | -5.5 | 3.9e-08 | 0.83 | 0.00 | 0.99 | FALSE |
| 3 | METSIM | Adipose | ACTR1B | 0.18 | 0.14 | lasso | 7 | 0.16 | 2.0e-22 | -5.5 | -5.3 | 1.2e-07 | 0.92 | 0.00 | 1.00 | FALSE |