TWAS hub - ACTR1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2850	0.0680	6.7e-09	0.146	NA	0.193	NA	0.180	5.2e-12	NA	1.1e-15	NA	1.4e-14
2	GTEx	Adipose Visceral Omentum	0.2560	0.0870	2.2e-03	0.166	NA	0.159	NA	0.182	5.5e-09	NA	1.3e-08	NA	9.6e-10
3	GTEx	Artery Aorta	0.1560	0.0680	1.4e-04	0.175	NA	0.163	NA	0.155	6.4e-10	NA	2.5e-09	NA	6.5e-09
4	GTEx	Artery Tibial	0.3125	0.0629	0.0e+00	0.254	NA	0.331	NA	0.335	6.3e-20	NA	1.3e-26	NA	4.8e-27
5	GTEx	Brain Cerebellum	0.3620	0.1130	9.3e-04	0.382	NA	0.344	NA	0.379	2.7e-12	NA	5.8e-11	NA	3.6e-12
6	GTEx	Colon Sigmoid	0.1560	0.0590	1.1e-05	0.046	NA	0.199	NA	0.201	1.0e-02	NA	1.3e-07	NA	1.2e-07
7	GTEx	Colon Transverse	0.1700	0.0720	3.8e-03	0.145	NA	0.134	NA	0.146	2.0e-07	NA	6.4e-07	NA	1.9e-07
8	GTEx	Esophagus Gastroesophageal Junction	0.2700	0.0950	3.8e-06	0.209	NA	0.220	NA	0.216	4.3e-08	NA	1.8e-08	NA	2.5e-08
9	GTEx	Esophagus Muscularis	0.2730	0.0670	1.6e-10	0.175	NA	0.239	NA	0.249	8.4e-11	NA	1.2e-14	NA	2.9e-15
10	GTEx	Lung	0.2020	0.0743	2.0e-03	0.126	NA	0.103	NA	0.119	7.3e-10	NA	3.0e-08	NA	2.4e-09
11	GTEx	Nerve Tibial	0.4211	0.0698	6.3e-10	0.190	NA	0.231	NA	0.188	1.7e-13	NA	2.3e-16	NA	2.4e-13
12	GTEx	Pancreas	0.0910	0.0490	2.8e-03	0.089	NA	0.085	NA	0.063	1.4e-04	NA	2.0e-04	NA	1.2e-03
13	GTEx	Pituitary	0.6800	0.0890	3.3e-04	0.500	NA	0.463	NA	0.488	1.6e-14	NA	3.4e-13	NA	4.8e-14
14	GTEx	Skin Sun Exposed Lower leg	0.1280	0.0510	7.4e-05	0.114	NA	0.113	NA	0.109	1.0e-09	NA	1.4e-09	NA	2.4e-09
15	GTEx	Spleen	0.2450	0.1190	1.5e-03	0.316	NA	0.231	NA	0.300	7.1e-09	NA	1.3e-06	NA	1.9e-08
16	GTEx	Testis	0.2260	0.0940	7.2e-04	0.214	NA	0.170	NA	0.197	7.4e-10	NA	5.1e-08	NA	4.1e-09
17	GTEx	Thyroid	0.4790	0.0750	1.8e-12	0.330	NA	0.314	NA	0.325	6.8e-26	NA	1.5e-24	NA	1.8e-25
18	GTEx	Vagina	0.3430	0.1260	4.7e-03	0.006	NA	-0.003	NA	-0.005	2.3e-01	NA	3.9e-01	NA	4.5e-01
19	GTEx	Whole Blood	0.0890	0.0420	9.7e-03	0.044	NA	0.030	NA	0.039	6.2e-05	NA	8.2e-04	NA	1.7e-04
20	METSIM	Adipose	0.1820	0.0459	5.0e-16	0.140	0.138	0.152	0.154	0.155	2.4e-20	4.5e-20	5.2e-22	2.3e-22	2.0e-22
21	ROSMAP	Brain Pre-frontal Cortex	0.2661	0.0539	2.8e-16	0.173	0.162	0.177	0.187	0.181	1.2e-21	2.6e-20	3.6e-22	1.8e-23	1.2e-22
22	YFS	Blood	0.1009	0.0267	0.0e+00	0.099	0.119	0.132	0.128	0.131	1.6e-30	7.2e-37	8.1e-41	1.2e-39	1.0e-40
23	TCGA	Cervical Squamous Cell Carcinoma	0.0620	0.0390	3.6e-03	0.033	0.012	0.009	NA	0.019	9.4e-03	7.6e-02	1.1e-01	NA	3.7e-02
24	TCGA	Head and Neck Squamous Cell Carcinoma	0.0765	0.0414	6.9e-05	0.005	0.035	0.044	NA	0.034	8.1e-02	7.9e-05	9.1e-06	NA	9.2e-05
25	TCGA	Stomach Adenocarcinoma	0.0820	0.0510	2.0e-03	0.008	0.030	0.022	NA	0.013	7.8e-02	2.8e-03	1.0e-02	NA	3.7e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Ever depressed for a whole week	10.6	13.0	18.8	-3.8	-3.2	-4.2	-4.0	-3.7	-4.1	-3.6	-3.5	-4.3	-3.6	-3.4	-4.0	-3.6	-3.5	-3.8	-3.6	-3.6	-4.3	-3.6	-3.8	-3.9	-4.1	-2.9	0.4	-0.6
Qualifications: nursing, teaching	8.4	13.0	20.5	-4.0	-3.2	-4.1	-4.3	-3.2	-4.3	-3.3	-4.2	-4.5	-3.2	-3.4	-3.5	-3.3	-3.4	-3.6	-3.2	-3.2	-4.5	-3.4	-3.7	-3.8	-4.3	-3.9	-0.4	-1.6
Mean Putamen Volume	7.3	8.3	14.4	-2.9	-2.6	-3.3	-3.4	-3.2	-3.0	-3.1	-2.5	-3.5	-3.2	-2.7	-1.6	-3.2	-2.4	-3.1	-3.2	-3.1	-2.9	-2.9	-3.0	-3.5	-3.8	-2.1	0.2	-0.2
Alcohol drinker status: Never	6.4	7.6	12.0	-3.4	-3.1	-3.1	-3.1	-3.1	-2.3	-3.1	-2.5	-2.8	-3.0	-2.7	-2.5	-3.1	-3.5	-3.0	-3.0	-3.0	-2.9	-2.7	-2.1	-3.0	-2.9	-1.0	1.4	0.4
Bipolar Disorder or Schizophrenia	6.3	15.5	26.1	-3.8	-4.0	-4.2	-3.4	-4.9	-2.3	-5.0	-0.9	-3.0	-5.0	-3.9	-3.1	-5.1	-3.3	-4.8	-5.0	-5.0	-2.9	-4.3	-4.4	-4.7	-3.3	1.4	2.8	3.8
Smoking Status	5.9	14.2	19.1	3.5	3.8	4.2	4.2	4.2	3.7	4.1	2.4	3.9	4.2	3.7	3.9	4.1	3.9	4.3	4.2	4.3	3.8	3.9	4.3	4.4	4.3	1.4	-1.2	-1.0
Bipolar Disorder (2018)	5.8	9.2	14.6	-3.1	-2.8	-3.5	-3.1	-3.4	-3.1	-3.4	-2.1	-3.1	-3.5	-2.9	-3.1	-3.5	-2.5	-3.4	-3.5	-3.4	-2.9	-3.2	-3.8	-3.4	-3.5	-1.1	1.0	1.2
Medication: Lansoprazole	5.7	6.5	9.9	2.5	2.8	2.6	2.2	3.1	1.3	3.1	0.6	2.3	3.1	2.5	2.9	3.1	2.9	2.9	3.1	3.1	1.9	2.9	2.9	3.1	2.2	-0.0	-1.8	-1.6
Loud music exposure frequency	5.7	6.2	9.3	-2.5	-2.9	-2.6	-2.5	-3.0	-1.5	-3.0	-1.7	-2.5	-3.0	-2.8	-1.8	-3.0	-1.9	-3.0	-3.0	-3.0	-2.4	-2.9	-2.4	-2.9	-2.0	-0.3	1.9	0.9
BMI	5.2	29.9	46.1	6.5	6.7	6.2	5.7	5.6	3.9	5.7	4.2	5.7	5.6	6.8	5.6	5.5	5.7	6.0	5.6	5.6	6.2	6.6	6.1	5.7	4.4	2.2	-3.8	-0.6
Fed-up feelings	5.1	9.4	20.5	3.5	4.0	3.0	2.5	3.6	0.6	3.8	1.3	2.9	3.6	4.5	2.0	3.7	3.0	3.1	3.6	3.6	2.4	4.1	3.5	3.5	1.5	0.1	-2.5	-0.7
Past tobacco smoking	5.1	9.4	13.8	-2.8	-2.9	-3.3	-3.3	-3.6	-2.9	-3.4	-1.9	-3.2	-3.5	-2.9	-2.9	-3.4	-3.5	-3.4	-3.5	-3.5	-2.9	-3.1	-3.6	-3.6	-3.7	-1.2	0.5	0.6
Ever unenthusiastic/disinterested for a whole week	4.8	5.8	10.5	-2.2	-1.7	-2.7	-2.9	-2.3	-2.9	-2.1	-2.7	-3.1	-2.2	-2.1	-3.2	-2.2	-1.9	-2.4	-2.2	-2.2	-2.8	-2.3	-2.7	-2.4	-3.0	-2.5	-0.3	-0.8
Ever smoked	4.7	8.3	12.6	2.7	2.9	3.0	3.0	3.5	2.3	3.4	1.6	2.9	3.5	2.9	2.7	3.4	3.0	3.3	3.5	3.5	2.4	3.1	3.1	3.4	3.1	0.5	-1.1	-0.9
Had menopause	4.3	5.4	7.0	-2.5	-2.3	-2.6	-2.5	-2.4	-1.9	-2.4	-2.4	-2.5	-2.4	-2.5	-2.6	-2.4	-2.5	-2.3	-2.4	-2.4	-2.4	-2.6	-2.6	-2.6	-2.3	-1.3	0.3	-0.5
Bipolar Disorder (2011)	4.2	4.0	9.7	-2.7	-2.9	0.0	-2.6	0.0	-2.0	0.0	-0.8	-2.1	0.0	-2.9	-2.7	0.0	-2.6	0.0	0.0	0.0	-2.4	0.0	-3.1	-3.0	-2.5	0.6	2.6	2.8
Blood Eosinophil Count	4.2	32.6	80.6	5.8	6.1	6.5	4.9	6.2	4.2	6.2	1.9	3.5	6.1	4.6	4.5	6.4	4.9	7.4	6.1	6.1	5.6	5.3	5.7	5.3	4.3	-2.4	-8.3	-9.0
Medication: Blood pressure	4.2	7.4	11.1	2.8	3.3	3.0	2.5	3.3	1.4	3.3	1.5	2.4	3.3	3.0	1.8	3.3	2.4	3.2	3.3	3.3	2.5	3.1	2.8	3.1	2.2	-0.2	-2.1	-1.6
Body mass index (BMI)	4.1	17.3	28.5	4.9	5.0	4.5	4.1	4.3	2.6	4.5	3.0	4.3	4.3	5.3	4.2	4.3	4.6	4.4	4.3	4.3	4.4	5.2	5.0	4.3	3.2	1.6	-3.0	-0.6
Friendships satisfaction	4.0	5.0	17.3	-1.7	-1.1	-2.3	-3.0	-1.5	-3.6	-1.3	-4.2	-3.0	-1.4	-1.2	-2.2	-1.3	-1.5	-1.9	-1.4	-1.4	-2.9	-1.3	-1.9	-1.9	-3.3	-3.5	-1.3	-1.6
Vascular/heart problems diagnosed by doctor	4.0	11.0	20.8	-3.6	-3.3	-3.6	-3.5	-3.0	-3.2	-3.1	-3.8	-3.6	-3.1	-3.7	-4.4	-3.1	-3.4	-3.2	-3.1	-3.0	-3.6	-3.7	-4.6	-3.4	-3.4	-2.4	0.6	-0.2
Schizophrenia (2018)	3.9	8.2	15.0	-2.3	-2.9	-2.6	-1.9	-3.7	-0.5	-3.7	0.6	-1.4	-3.8	-2.8	-2.0	-3.8	-2.3	-3.5	-3.8	-3.8	-1.4	-3.3	-3.0	-3.3	-1.5	2.6	2.8	3.9
Impedance of arm (right)	3.9	18.4	30.2	-5.1	-5.3	-4.6	-4.1	-4.6	-2.2	-4.8	-2.5	-3.9	-4.6	-5.4	-4.4	-4.6	-4.4	-4.7	-4.6	-4.6	-4.3	-5.5	-5.1	-4.4	-3.2	-0.5	4.0	1.6
Leg pain on walking	3.9	4.9	9.1	2.4	2.8	2.2	1.9	2.6	1.1	2.7	1.4	2.2	2.7	3.0	1.2	2.7	2.0	2.3	2.7	2.6	1.8	2.8	2.7	2.6	1.6	0.3	-1.6	-0.8
Impedance of arm (left)	3.8	17.4	30.6	-4.8	-5.1	-4.3	-3.8	-4.5	-1.9	-4.6	-2.3	-3.8	-4.5	-5.5	-4.4	-4.5	-4.5	-4.5	-4.5	-4.4	-4.0	-5.5	-5.3	-4.2	-2.9	-0.5	3.9	1.6
Diastolic blood pressure, automated reading	3.8	11.8	20.5	3.3	2.8	3.8	4.1	3.3	4.3	3.1	4.0	4.0	3.2	3.0	4.5	3.1	3.9	3.5	3.2	3.1	4.0	2.9	3.4	3.4	4.5	3.1	0.1	0.4
Cardiovascular Disease	3.7	12.1	29.0	4.0	3.3	4.0	3.8	2.8	4.0	3.0	4.0	3.7	2.9	3.6	5.4	2.9	3.3	3.4	2.9	2.8	4.1	3.7	5.0	3.3	3.6	2.6	-0.9	-0.1
Medication: Amlodipine	3.7	5.1	7.6	2.5	2.4	2.5	2.3	2.5	1.8	2.6	1.4	2.4	2.5	2.5	2.3	2.6	2.0	2.6	2.5	2.5	2.2	2.7	2.8	2.6	2.1	0.8	-1.1	-0.5
Alcohol intake frequency.	3.7	8.6	15.6	-2.5	-2.6	-3.1	-3.1	-4.0	-2.7	-3.7	-1.4	-2.8	-3.9	-2.2	-1.6	-3.8	-3.2	-3.6	-3.9	-3.9	-2.2	-2.7	-2.1	-3.6	-3.5	0.0	0.9	1.4
Tinnitus: Yes, now most or all of the time	3.7	4.3	12.5	-2.3	-1.2	-2.5	-2.7	-1.6	-3.5	-1.6	-2.7	-2.3	-1.6	-1.2	-2.5	-1.8	-1.9	-2.2	-1.6	-1.6	-2.8	-1.3	-2.0	-1.9	-2.8	-2.2	-0.7	-0.4
Reaction Time	3.5	6.7	9.5	2.8	2.6	2.9	3.0	2.7	2.3	2.8	1.8	2.5	2.8	2.7	3.0	2.8	2.5	3.0	2.8	2.7	2.7	2.9	3.1	2.9	2.9	0.7	-1.1	-0.6
Commuting to job workplace: Car/motor vehicle	3.5	4.0	5.9	2.2	2.0	2.4	2.1	2.2	2.1	2.2	1.8	2.3	2.3	1.9	1.6	2.2	1.7	2.3	2.3	2.2	2.2	1.9	1.8	2.4	2.1	1.1	-0.6	-0.2
Leg fat mass (right)	3.3	12.8	20.0	4.1	4.2	4.0	3.7	3.8	2.5	3.8	3.1	3.9	3.8	4.5	3.5	3.6	4.1	3.8	3.8	3.8	3.9	4.3	3.8	3.8	2.9	1.7	-2.1	0.1
High blood pressure	3.2	8.8	15.8	3.2	2.9	3.2	3.1	2.8	2.8	2.9	3.4	3.3	2.8	3.4	3.9	2.9	3.1	2.9	2.8	2.8	3.1	3.3	4.0	3.1	3.0	2.1	-0.6	0.1
Exposure to tobacco smoke outside home	3.2	4.3	7.7	2.1	2.7	1.9	1.9	2.4	0.7	2.4	1.1	2.0	2.4	2.8	1.9	2.3	2.0	2.2	2.4	2.4	1.6	2.7	2.5	2.2	1.6	0.3	-1.7	-0.6
Leg fat percentage (left)	3.2	11.7	18.7	3.6	4.0	3.7	3.3	3.7	2.2	3.7	2.5	3.5	3.7	4.3	3.6	3.6	3.8	3.6	3.7	3.7	3.4	4.2	4.2	3.6	2.7	1.2	-2.4	-0.9
Age started oral contraceptive pill	3.2	4.0	8.4	-2.2	-1.9	-2.0	-2.1	-1.9	-1.7	-1.9	-1.5	-2.3	-1.9	-2.4	-2.6	-1.9	-2.1	-1.9	-1.9	-1.9	-2.0	-2.5	-2.9	-2.0	-1.9	-1.5	0.7	-0.3
Ever used hormone-replacement therapy (HRT)	3.1	3.9	5.7	2.2	2.3	2.1	2.0	2.2	1.2	2.3	1.3	2.0	2.3	2.3	1.6	2.3	2.2	2.1	2.3	2.3	1.8	2.4	2.3	2.4	1.7	0.5	-0.9	-0.2
Leg fat mass (left)	3.1	12.3	19.1	3.9	4.1	3.9	3.6	3.8	2.4	3.8	2.9	3.8	3.7	4.4	3.4	3.6	4.1	3.7	3.7	3.8	3.7	4.2	3.8	3.7	2.9	1.6	-2.0	0.0
Alcohol usually taken with meals	3.0	4.8	9.1	-2.4	-2.7	-2.8	-2.4	-2.1	-2.1	-2.1	-1.6	-2.5	-2.2	-2.8	-1.5	-2.0	-2.3	-2.5	-2.2	-2.2	-3.0	-2.3	-2.4	-2.4	-1.7	-1.4	1.0	0.2
Leg fat percentage (right)	3.0	10.8	17.6	3.7	4.0	3.7	3.2	3.5	2.1	3.5	2.6	3.4	3.5	4.2	3.3	3.4	3.5	3.5	3.5	3.5	3.5	4.0	3.8	3.4	2.5	1.2	-2.5	-0.8
Mouth/teeth dental problems: Loose teeth	3.0	3.6	7.1	2.3	2.6	1.9	1.8	2.1	0.6	2.2	0.7	1.9	2.1	2.7	1.5	2.2	1.9	2.0	2.1	2.1	1.8	2.5	1.9	2.0	1.3	0.4	-1.4	0.1
Average weekly beer plus cider intake	3.0	4.3	8.5	1.8	1.5	2.3	2.7	1.9	2.9	1.8	1.7	2.7	1.9	1.6	1.5	1.8	2.0	2.4	1.9	1.9	2.7	1.9	2.3	2.3	2.8	2.4	0.1	0.4
Mean time to correctly identify matches	2.9	5.5	8.5	2.4	2.5	2.6	2.7	2.4	2.1	2.4	1.8	2.3	2.4	2.4	2.9	2.3	2.2	2.7	2.4	2.4	2.6	2.6	2.9	2.5	2.7	0.8	-1.0	-0.5
Hypertension (Self-reported)	2.9	8.1	15.1	3.1	2.7	3.1	3.0	2.6	2.9	2.7	3.3	3.1	2.6	3.1	3.7	2.7	2.9	2.8	2.6	2.6	3.0	3.1	3.9	2.9	3.0	2.0	-0.3	0.2
Waist circumference	2.8	10.3	15.2	3.7	3.9	3.5	3.3	3.3	2.2	3.4	2.6	3.3	3.3	3.9	3.3	3.2	3.8	3.5	3.3	3.3	3.6	3.8	3.4	3.4	2.5	1.3	-2.4	-0.4
Arm fat mass (left)	2.8	11.4	18.5	3.9	4.0	3.6	3.4	3.6	2.2	3.6	2.6	3.6	3.6	4.3	3.3	3.5	3.8	3.6	3.6	3.6	3.5	4.2	3.7	3.6	2.6	1.4	-2.2	-0.1
Intelligence (Savage-Jansen 2018)	2.7	8.3	12.3	-3.0	-2.9	-3.2	-3.4	-2.9	-2.8	-2.9	-2.4	-3.1	-2.9	-3.2	-3.5	-2.8	-2.0	-3.3	-2.9	-2.8	-3.3	-3.2	-3.5	-2.9	-2.9	-1.6	1.7	0.8
Tinnitus: Yes, but not now, but have in the past	2.7	2.9	5.4	-1.8	-2.1	-1.7	-1.5	-2.3	-0.5	-2.3	-0.4	-1.3	-2.3	-1.9	-1.1	-2.3	-1.3	-1.9	-2.3	-2.3	-0.9	-1.9	-1.4	-2.1	-1.6	0.7	1.3	1.1
Arm fat mass (right)	2.7	11.3	19.3	3.9	4.0	3.6	3.3	3.6	2.0	3.6	2.4	3.4	3.6	4.4	3.3	3.5	3.8	3.5	3.6	3.6	3.4	4.2	3.8	3.5	2.5	1.1	-2.4	-0.3
Supplements: Fish oil (including cod liver oil)	2.7	3.5	6.2	-2.0	-1.7	-2.0	-2.2	-1.9	-1.9	-1.9	-2.2	-2.5	-1.9	-1.6	-1.4	-1.9	-1.6	-2.0	-1.9	-1.9	-2.3	-1.9	-1.6	-2.0	-1.9	-2.0	-0.1	-1.1
Schizophrenia (2014)	2.6	5.6	11.2	-1.9	-2.1	-2.3	-1.7	-3.2	-0.9	-3.2	0.0	-1.6	-3.3	-2.2	-1.2	-3.3	-1.8	-2.8	-3.3	-3.2	-1.1	-2.5	-2.6	-2.9	-1.8	1.5	1.7	3.0
Diverticular disease/diverticulitis (self-reported)	2.6	3.1	5.5	-1.4	-2.1	-2.0	-1.6	-2.3	-1.2	-2.1	-0.8	-1.9	-2.3	-1.7	-0.2	-2.1	-2.3	-2.0	-2.3	-2.3	-1.6	-1.7	-1.0	-2.3	-1.7	-0.3	0.8	0.4
Qualifications: College or University degree	2.5	7.8	19.2	-2.9	-2.7	-2.9	-2.8	-2.5	-1.9	-2.5	-2.6	-3.4	-2.6	-4.1	-3.6	-2.4	-2.6	-2.4	-2.6	-2.5	-2.9	-3.7	-4.4	-2.8	-2.1	-2.4	0.9	-0.8
Commuting to job workplace: Public transport	2.5	3.0	6.9	-1.9	-1.0	-1.8	-2.0	-1.2	-2.4	-1.3	-2.1	-2.4	-1.3	-1.6	-1.6	-1.3	-1.5	-1.4	-1.3	-1.2	-2.1	-1.6	-2.0	-1.7	-2.0	-2.6	-0.8	-1.6
Coronary Artery Disease (CAD)	2.4	2.9	5.9	2.0	2.4	1.9	1.5	1.9	0.9	1.9	0.8	1.4	1.8	2.3	1.7	1.8	1.4	1.9	1.8	1.8	1.7	2.0	1.8	1.8	1.1	-0.0	-1.5	-0.9
Heart attack	2.4	3.1	5.2	1.8	2.2	1.8	1.3	2.2	0.2	2.3	-0.5	1.2	2.3	2.0	0.9	2.3	0.9	2.0	2.3	2.2	1.3	2.2	1.8	2.1	1.0	-0.9	-1.9	-1.4
Arm fat-free mass (right)	2.4	12.2	18.1	4.2	4.2	3.9	3.9	3.8	2.5	3.9	2.9	3.6	3.8	4.1	2.9	3.8	4.0	4.0	3.8	3.8	4.0	4.1	2.8	3.7	2.9	1.1	-2.4	0.1
Number of children fathered	2.4	2.7	4.0	1.8	2.0	1.9	1.6	1.9	0.9	1.9	0.9	1.4	1.9	1.9	1.5	1.8	1.7	1.9	1.9	1.9	1.8	1.9	1.6	1.7	1.1	-0.1	-1.8	-1.2
Knee pain experienced in last month	2.4	3.7	7.8	2.6	2.8	2.3	1.9	2.0	1.0	2.2	0.9	1.8	2.0	2.6	1.2	2.0	2.0	2.1	2.0	2.0	2.2	2.4	1.7	2.0	1.3	0.2	-1.9	-0.3
Osteoarthritis (self-reported)	2.4	3.2	5.2	2.3	2.2	2.1	1.9	2.0	1.4	2.1	1.4	2.0	2.0	1.8	0.5	2.1	1.6	2.0	2.0	2.0	2.1	1.9	1.2	2.0	1.8	0.7	-0.8	0.2
Heart attack/myocardial infarction (self-reported)	2.4	3.1	5.3	1.8	2.2	1.8	1.3	2.2	0.1	2.3	-0.5	1.3	2.3	2.1	0.7	2.3	0.8	2.0	2.3	2.3	1.2	2.2	1.7	2.1	1.0	-0.9	-1.8	-1.3
Rheumatoid Arthritis	2.3	3.2	6.7	-2.0	-1.4	-1.9	-2.2	-1.3	-2.5	-1.4	-2.3	-2.3	-1.3	-1.2	-2.1	-1.4	-1.6	-1.4	-1.3	-1.3	-1.8	-1.0	-1.2	-2.0	-2.6	-2.4	-1.5	-1.6
Hip circumference	2.3	10.0	16.1	3.8	3.7	3.4	3.5	3.3	2.3	3.3	3.1	3.5	3.2	3.9	2.6	3.2	4.0	3.3	3.2	3.3	3.5	3.7	2.8	3.3	2.7	1.8	-1.4	0.9
Alcohol intake versus 10 years previously	2.3	3.5	6.7	2.3	2.5	1.9	1.7	1.9	0.8	2.0	1.3	1.8	1.9	2.6	1.6	2.0	2.1	1.9	1.9	1.9	2.0	2.5	2.2	1.8	1.4	0.4	-1.8	-0.4
Noisy workplace	2.3	2.9	9.9	1.6	2.8	1.3	0.4	1.9	-0.7	2.1	-0.6	0.4	2.0	2.1	-0.8	1.9	0.6	1.5	2.0	1.9	0.7	1.9	1.1	1.5	-0.0	-2.2	-3.1	-2.5
Medication for cholesterol, blood pressure or diabetes	2.3	3.7	6.0	-1.8	-2.4	-2.0	-1.3	-2.4	-0.5	-2.4	-0.6	-1.3	-2.4	-2.0	-1.0	-2.4	-1.8	-2.3	-2.4	-2.4	-1.5	-2.2	-2.1	-2.0	-1.2	1.0	2.3	2.2
Whole body fat mass	2.3	9.6	14.7	3.5	3.6	3.4	3.2	3.3	2.1	3.3	2.5	3.3	3.3	3.8	2.9	3.2	3.7	3.3	3.3	3.3	3.3	3.7	3.1	3.3	2.5	1.4	-1.8	0.0
Arm predicted mass (left)	2.3	11.6	18.7	4.0	4.2	3.7	3.6	3.8	2.0	3.8	2.4	3.4	3.7	4.3	2.9	3.7	4.0	3.8	3.7	3.8	3.6	4.2	3.0	3.6	2.5	0.8	-2.6	0.1
Medication: Cholesterol lowering	2.2	3.4	5.4	1.7	2.0	2.0	1.4	2.3	0.9	2.2	0.8	1.4	2.3	1.7	1.3	2.2	2.0	2.2	2.3	2.3	1.6	2.1	2.1	2.0	1.4	-0.6	-1.9	-1.9
Emphysema/chronic bronchitis	2.2	2.4	4.8	2.0	1.9	1.9	1.7	1.3	1.6	1.4	1.1	1.5	1.3	1.7	1.8	1.3	1.9	1.7	1.3	1.3	2.2	1.7	1.7	1.6	1.4	0.9	-1.1	-0.3
Average weekly spirits intake	2.1	2.6	3.9	1.7	1.5	1.9	1.8	1.9	1.4	1.8	1.1	2.0	1.9	1.6	0.2	1.8	1.8	1.7	1.9	1.9	1.6	1.7	1.3	2.0	1.9	0.9	-0.2	0.4
Qualifications: CSEs or equivalent	2.1	2.7	5.2	2.3	1.7	1.7	1.9	1.5	1.3	1.6	1.7	2.2	1.4	2.1	1.8	1.6	1.6	1.5	1.4	1.4	1.9	1.8	1.3	1.7	1.4	1.8	-0.7	1.0
Mouth/teeth dental problems	2.1	3.2	9.5	-1.9	-2.5	-1.7	-1.2	-1.9	0.0	-1.9	0.6	-1.0	-1.8	-2.6	-1.5	-1.8	-1.8	-1.9	-1.8	-1.8	-1.4	-2.3	-2.1	-1.5	-0.7	0.9	3.1	2.0
Arm predicted mass (right)	2.1	10.8	16.3	4.0	4.0	3.7	3.6	3.6	2.3	3.7	2.5	3.3	3.6	3.9	2.6	3.6	3.7	3.8	3.6	3.6	3.7	3.8	2.4	3.5	2.7	0.9	-2.4	0.1
Pulse rate, automated reading	2.1	6.7	11.9	3.0	2.5	3.3	3.2	2.4	3.5	2.5	2.6	2.8	2.4	1.9	2.8	2.5	2.7	3.0	2.4	2.4	3.3	1.9	2.0	2.8	3.3	1.8	-0.9	-0.8
Alcohol drinker status: Previous	2.1	2.4	10.1	-0.6	-1.4	-0.7	-0.2	-1.9	1.0	-1.8	1.5	-0.1	-1.8	-1.2	0.1	-1.8	-0.7	-1.4	-1.8	-1.9	0.3	-1.4	-0.7	-1.2	-0.0	2.5	3.1	3.2
Hypothyroidism (self reported)	2.0	4.6	14.5	-1.1	-0.4	-1.9	-2.5	-1.2	-3.6	-1.1	-3.4	-2.6	-1.3	-0.6	-2.4	-1.1	-1.8	-1.3	-1.3	-1.3	-1.7	-0.9	-2.4	-2.2	-3.8	-3.3	-3.0	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.5	10.7	2.1	2.9	1.8	1.1	2.8	-0.8	2.8	-0.6	1.1	2.8	2.7	-0.6	2.8	1.1	2.1	2.8	2.7	0.8	2.6	1.4	2.0	0.6	-2.0	-3.3	-2.1
Financial difficulties in last 2 years	2.0	2.6	7.1	1.7	1.3	1.7	2.0	1.2	2.2	1.2	1.8	1.7	1.2	1.6	2.7	1.2	1.6	1.6	1.2	1.2	2.0	1.6	2.4	1.4	2.0	1.4	-0.3	0.1
Weight	2.0	10.0	15.3	3.9	3.7	3.6	3.4	3.3	2.3	3.4	2.8	3.4	3.3	3.8	2.8	3.3	3.8	3.4	3.3	3.3	3.5	3.7	2.9	3.4	2.5	1.4	-1.8	0.3
Happiness	2.0	2.5	7.7	-0.9	-0.3	-1.4	-2.1	-1.1	-2.6	-0.9	-2.8	-2.2	-1.1	-0.5	-1.1	-0.9	-1.3	-1.4	-1.1	-1.1	-1.8	-0.7	-0.8	-1.4	-2.4	-2.7	-1.4	-1.6
Arm fat-free mass (left)	2.0	10.1	16.3	3.8	3.9	3.5	3.3	3.5	1.8	3.6	2.2	3.1	3.5	4.0	2.7	3.5	3.7	3.6	3.5	3.5	3.4	4.0	2.8	3.3	2.3	0.7	-2.6	-0.2
Impedance of whole body	2.0	10.2	18.2	-4.1	-4.0	-3.3	-3.0	-3.2	-1.6	-3.4	-2.0	-3.0	-3.2	-4.2	-3.6	-3.3	-3.4	-3.3	-3.2	-3.2	-3.3	-4.3	-4.1	-3.1	-2.2	-0.8	2.9	0.7
Major Depression (MDD)	1.9	2.3	9.7	1.8	2.2	1.2	0.8	1.5	-0.5	1.6	-0.3	0.4	1.5	2.1	1.0	1.5	1.2	1.5	1.5	1.5	1.0	1.9	1.3	1.1	-0.1	-1.5	-3.1	-1.9
Medication: Co-codamol	1.9	2.3	4.3	1.8	2.0	1.6	1.4	1.4	1.0	1.5	1.4	1.5	1.4	2.0	1.4	1.4	1.3	1.5	1.4	1.4	1.9	2.1	2.0	1.4	0.8	0.5	-1.5	-0.3
Wears glasses or contact lenses	1.9	2.2	6.8	-1.8	-1.7	-1.1	-1.2	-1.6	0.2	-1.7	-0.6	-1.5	-1.6	-2.6	-1.5	-1.7	-1.5	-1.1	-1.6	-1.6	-0.9	-2.3	-2.3	-1.4	-0.7	-0.3	0.8	-0.5
Illnesses of father: High blood pressure	1.9	2.3	3.5	1.8	1.4	1.8	1.6	1.8	1.4	1.8	1.8	1.9	1.8	1.8	0.5	1.8	1.4	1.5	1.8	1.7	1.5	1.2	0.8	1.7	1.5	1.0	0.4	0.6
Pulse wave reflection index	1.8	2.2	6.8	1.2	1.0	1.5	1.3	1.6	1.3	1.5	0.7	1.5	1.6	1.4	2.5	1.6	1.4	1.4	1.6	1.5	1.1	1.7	2.6	1.6	1.7	0.6	-0.3	-0.8
Illnesses of siblings: Diabetes	1.8	2.2	4.3	-2.1	-1.8	-1.9	-1.8	-1.6	-1.7	-1.6	-1.3	-1.6	-1.5	-1.4	-0.3	-1.6	-1.4	-1.8	-1.5	-1.5	-2.1	-1.2	-0.5	-1.5	-1.4	-0.8	0.6	-0.1
Smoking status: Current	1.8	2.9	4.8	1.4	2.0	1.6	1.5	2.1	0.6	2.1	0.7	1.7	2.2	2.2	1.9	2.0	1.5	1.8	2.2	2.1	1.3	2.2	1.9	1.9	1.2	-0.0	-1.2	-0.6
Schizophrenia vs Biploar Disorder	1.7	2.3	7.3	1.4	0.9	1.7	2.0	1.1	2.7	1.1	2.2	1.7	0.0	0.6	2.3	1.1	1.5	1.6	0.0	1.1	2.1	0.9	1.4	1.4	2.2	1.7	0.1	0.2
Fasting Glucose	1.7	2.0	5.2	1.2	1.5	1.6	1.7	1.4	1.4	1.3	2.3	1.9	1.4	1.4	0.7	1.2	0.6	1.4	1.4	1.3	1.8	1.3	1.2	1.3	1.8	1.6	0.5	1.1
Smoking status: Previous	1.7	2.5	6.1	1.3	1.1	1.7	1.7	1.6	2.2	1.5	1.2	1.8	1.6	1.0	1.4	1.5	2.2	1.6	1.6	1.6	1.5	1.2	2.0	1.8	2.5	1.3	0.8	0.1
High blood pressure (mother)	1.6	2.3	3.4	1.9	1.6	1.7	1.7	1.6	1.5	1.6	1.6	1.5	1.6	1.4	1.7	1.6	1.7	1.6	1.6	1.6	1.5	1.5	1.6	1.7	1.7	0.5	-0.4	-0.1
Pulse rate	1.6	2.6	6.3	1.9	1.3	1.9	2.2	1.0	2.4	1.0	2.3	2.1	1.0	1.1	1.5	1.0	1.8	1.4	1.0	1.0	2.3	0.9	0.2	1.5	2.0	2.5	0.5	1.7
Heart disease (mother)	1.6	2.0	3.6	-1.4	-1.2	-1.4	-1.5	-1.4	-1.6	-1.4	-1.8	-1.7	-1.4	-1.3	-0.8	-1.4	-1.6	-1.3	-1.4	-1.3	-1.4	-1.4	-1.9	-1.5	-1.8	-1.4	-0.5	-0.5
Arm fat percentage (left)	1.6	6.3	10.4	2.8	2.9	2.7	2.5	2.5	1.7	2.6	2.1	2.8	2.5	3.2	2.8	2.5	2.9	2.5	2.5	2.5	2.7	3.1	3.2	2.6	2.0	1.4	-1.5	-0.1
Medication: Lisinopril	1.6	2.1	3.6	1.6	1.6	1.7	1.8	1.6	1.6	1.6	1.7	1.8	1.6	1.1	0.7	1.5	1.6	1.7	1.6	1.6	1.9	1.1	0.1	1.6	1.5	1.0	-0.3	0.6
Body fat percentage	1.5	5.9	9.9	2.6	2.8	2.7	2.4	2.6	1.6	2.6	1.9	2.6	2.6	3.1	2.3	2.5	2.9	2.5	2.6	2.6	2.5	3.0	2.9	2.6	1.9	1.1	-1.6	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	1.9	6.1	1.5	1.9	1.0	0.5	1.5	-1.0	1.7	-0.4	0.5	1.6	2.0	0.3	1.7	1.1	1.2	1.6	1.6	0.4	1.8	1.0	1.4	-0.3	-1.5	-2.5	-1.4
Mineral and other dietary supplements	1.5	2.0	3.2	1.3	1.2	1.6	1.7	1.5	1.5	1.4	1.4	1.7	1.5	1.1	1.2	1.4	1.5	1.7	1.5	1.5	1.8	1.3	1.3	1.5	1.5	1.1	-0.5	-0.2
Trunk fat mass	1.4	6.1	9.4	2.8	2.8	2.7	2.6	2.6	1.9	2.6	2.2	2.8	2.6	3.0	2.3	2.5	3.1	2.6	2.6	2.6	2.6	2.9	2.5	2.7	2.1	1.4	-1.1	0.3
Qualifications: A levels/AS levels or equivalent	1.4	3.0	9.8	-1.8	-1.3	-1.7	-2.0	-1.3	-1.7	-1.4	-1.5	-1.9	-1.4	-2.1	-2.6	-1.4	-1.8	-1.7	-1.4	-1.3	-2.0	-2.1	-3.1	-1.5	-1.8	-1.6	0.6	0.0
Tense / ‘highly strung’	1.4	2.3	4.1	1.8	1.8	1.7	1.4	1.6	0.8	1.7	0.7	1.3	1.6	2.0	1.3	1.7	1.3	1.8	1.6	1.6	1.6	1.8	1.5	1.6	0.7	0.0	-2.0	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.8	8.8	-1.8	-1.4	-1.9	-2.0	-1.0	-2.4	-1.1	-1.9	-1.9	-1.0	-1.6	-3.0	-1.0	-1.5	-1.6	-1.0	-0.9	-2.5	-1.4	-2.1	-1.2	-2.0	-2.1	0.1	-0.4
Basal metabolic rate	1.4	8.0	13.0	3.6	3.4	3.1	3.1	3.0	2.0	3.1	2.5	3.0	2.9	3.4	2.5	3.0	3.4	3.1	2.9	3.0	3.2	3.3	2.1	3.0	2.2	1.3	-1.7	0.7
Depressed Affect (Nagel 2018)	1.3	2.8	8.0	2.2	2.5	1.4	1.1	1.9	-0.4	2.2	0.6	1.4	2.0	2.8	1.0	2.1	1.2	1.4	2.0	1.9	0.9	2.4	2.0	2.0	0.4	-0.4	-1.6	-0.4
Body Mass Index (BMI) (2010)	1.3	1.7	3.7	1.6	1.8	1.6	1.2	1.4	0.6	1.5	-0.6	0.6	1.4	1.2	1.0	1.5	0.6	1.8	1.4	1.4	1.4	1.5	1.0	1.3	0.9	-0.8	-1.9	-1.4
Diabetes (father)	1.3	1.6	2.9	-1.2	-1.7	-1.4	-1.0	-1.5	-0.4	-1.5	0.2	-0.8	-1.6	-1.5	-0.1	-1.5	-1.3	-1.5	-1.6	-1.6	-1.1	-1.5	-1.6	-1.5	-0.7	0.6	1.3	1.2
Diabetes (mother)	1.3	1.7	6.3	1.3	1.5	1.0	0.7	1.5	-0.3	1.6	-0.4	0.3	1.5	1.6	0.1	1.6	1.2	1.5	1.5	1.5	0.7	1.3	0.2	1.2	-0.1	-1.6	-2.5	-1.8
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	3.6	1.3	1.2	1.3	1.5	1.5	1.2	1.5	1.4	1.8	1.5	1.9	1.3	1.5	1.7	1.3	1.5	1.4	1.3	1.7	1.6	1.5	1.3	1.2	0.1	0.6
Medication: Ramipril	1.3	1.6	3.1	1.4	1.6	1.1	0.7	1.5	-0.1	1.6	0.3	0.7	1.5	1.6	1.1	1.6	0.9	1.3	1.5	1.5	0.7	1.6	1.5	1.4	0.4	-0.9	-1.8	-1.5
Arm fat percentage (right)	1.3	5.2	10.2	2.5	2.7	2.3	2.1	2.3	1.2	2.3	1.7	2.4	2.3	3.2	2.6	2.2	2.7	2.2	2.3	2.3	2.3	3.0	3.1	2.3	1.6	1.1	-1.6	-0.2
Eye problems/disorders: None of the above	1.3	1.5	2.8	-1.3	-1.1	-1.2	-1.3	-1.3	-0.6	-1.4	-0.2	-1.7	-1.4	-1.6	-0.7	-1.4	-0.6	-1.1	-1.4	-1.3	-0.8	-1.6	-1.1	-1.5	-1.4	-1.1	-0.4	-1.4
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.5	1.7	1.5	1.3	1.6	1.2	1.0	1.3	1.9	1.6	1.2	1.8	0.2	1.2	1.0	1.2	1.2	1.1	1.5	1.4	0.7	1.3	1.1	1.2	-0.2	1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.8	5.8	1.8	2.0	1.6	1.2	2.3	0.0	2.4	0.1	1.3	2.3	2.1	-0.5	2.4	0.9	1.8	2.3	2.3	0.7	2.0	1.1	1.8	1.2	-0.9	-1.9	-1.2
Medication: Atenolol	1.2	1.5	2.5	1.4	1.5	1.6	1.0	1.3	0.5	1.4	0.5	1.0	1.4	1.4	0.6	1.4	1.1	1.4	1.4	1.4	1.3	1.5	1.6	1.4	0.8	-0.2	-1.1	-0.9
Medication: Simvastatin	1.2	1.8	5.7	1.1	1.4	1.2	0.6	1.6	-0.1	1.6	-0.1	0.7	1.6	1.4	1.4	1.6	1.1	1.2	1.6	1.6	0.6	1.7	2.4	1.3	0.7	-0.8	-1.6	-2.0
Illnesses of siblings	1.2	1.7	3.2	1.8	1.7	1.4	1.5	1.2	1.1	1.4	1.6	1.6	1.2	1.3	0.9	1.3	1.3	1.3	1.2	1.2	1.7	1.4	0.5	1.3	1.0	1.1	-0.1	1.4
Exposure to tobacco smoke at home	1.2	1.3	3.3	1.0	1.0	1.1	1.2	1.1	0.9	1.1	1.3	1.2	1.1	0.9	1.8	1.1	1.3	1.2	1.1	1.1	1.2	1.4	1.8	1.1	1.0	0.7	-0.5	-0.2
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	8.9	-0.4	0.4	-0.8	-1.6	-0.1	-2.6	-0.0	-2.8	-1.6	-0.2	0.1	-1.9	-0.1	-0.6	-0.3	-0.2	-0.2	-0.9	-0.0	-1.4	-1.0	-2.6	-3.0	-3.0	-2.1
High blood pressure (siblings)	1.2	1.8	5.2	-1.4	-1.4	-1.1	-1.5	-1.1	-1.0	-1.1	-1.9	-1.7	-1.1	-1.4	-1.4	-1.0	-1.3	-1.0	-1.1	-1.1	-1.7	-1.4	-0.4	-1.2	-0.8	-1.6	-0.6	-2.3
Number of full sisters	1.2	1.4	5.2	0.9	1.3	1.3	1.3	1.2	0.9	1.0	0.7	1.0	1.2	1.5	2.3	0.9	1.3	1.2	1.2	1.2	1.1	1.4	1.8	1.3	1.1	0.3	-0.0	0.1
Whole body fat-free mass	1.2	6.8	11.4	3.4	3.1	2.9	3.0	2.7	1.9	2.8	2.4	2.8	2.7	3.1	2.3	2.8	3.2	2.9	2.7	2.7	3.0	3.0	1.8	2.7	2.1	1.2	-1.5	0.8
Pain experienced in last month	1.2	2.0	3.8	-1.8	-1.7	-1.5	-1.6	-1.4	-0.7	-1.5	-1.1	-1.5	-1.4	-1.9	-2.0	-1.4	-1.7	-1.3	-1.4	-1.4	-1.3	-1.6	-1.6	-1.5	-1.3	-0.7	0.8	0.2
Height	1.1	21.5	58.1	-4.4	-4.7	-4.7	-4.3	-4.7	-3.5	-4.7	-3.7	-4.8	-4.8	-5.6	-5.9	-4.7	-4.4	-4.4	-4.8	-4.7	-4.3	-5.8	-7.6	-4.9	-4.4	-2.0	2.2	1.6
Pack years adult smoking proportion	1.1	1.6	2.6	1.6	1.5	1.4	1.3	1.3	0.8	1.4	0.7	1.4	1.4	1.3	1.6	1.4	1.0	1.4	1.4	1.3	1.5	1.6	1.2	1.3	0.7	0.6	-1.1	0.0
Mouth/teeth dental problems: Dentures	1.1	1.9	6.5	1.7	1.8	1.6	1.3	1.5	0.5	1.5	0.0	1.0	1.5	1.5	0.2	1.5	0.6	1.8	1.5	1.5	1.4	1.4	0.8	1.3	0.8	-0.5	-2.5	-1.7
Migraine (self-reported)	1.1	1.4	3.9	-1.3	-0.9	-1.5	-1.6	-0.9	-1.6	-0.9	-0.4	-0.7	-0.9	-0.8	-2.0	-1.0	-1.3	-1.6	-0.9	-1.0	-1.6	-0.9	-1.0	-1.1	-1.5	-0.0	1.0	1.0
Overall health rating	1.1	2.3	6.3	2.1	2.4	1.5	1.1	1.5	-0.2	1.7	-0.0	1.4	1.5	2.5	0.9	1.5	1.7	1.4	1.5	1.5	1.5	2.1	1.1	1.4	0.2	0.2	-2.2	-0.1
Whole body water mass	1.1	6.4	10.8	3.3	3.1	2.8	2.8	2.7	1.8	2.8	2.2	2.7	2.6	3.0	2.2	2.7	3.1	2.8	2.6	2.7	2.9	3.0	1.8	2.6	1.9	1.1	-1.6	0.7
Financial situation satisfaction	1.1	1.4	3.1	1.3	1.3	1.3	1.0	1.3	0.7	1.3	0.1	0.9	1.3	1.4	1.1	1.3	1.6	1.2	1.3	1.3	0.9	1.4	1.8	1.3	1.0	-0.1	-0.9	-0.9
Medication for hormone replacement therapy	1.0	1.2	2.2	1.5	1.0	1.1	1.2	1.0	0.8	1.1	1.4	1.3	1.0	1.3	0.9	1.1	1.2	1.0	1.0	1.0	1.1	1.2	0.9	1.2	0.9	0.8	-0.0	0.8
Leg fat-free mass (left)	1.0	5.5	9.7	3.1	2.8	2.6	2.7	2.4	1.8	2.5	2.3	2.7	2.3	2.7	1.9	2.4	2.9	2.5	2.3	2.3	2.8	2.6	1.5	2.4	1.9	1.5	-1.0	1.2
Trunk fat percentage	1.0	3.8	6.3	2.0	2.2	2.1	2.0	2.1	1.4	2.0	1.6	2.2	2.1	2.5	1.8	2.0	2.5	2.0	2.1	2.1	2.0	2.3	2.2	2.1	1.7	1.1	-0.9	0.1
Leg predicted mass (left)	1.0	5.6	9.9	3.1	2.9	2.6	2.7	2.4	1.8	2.5	2.3	2.7	2.3	2.7	1.9	2.4	2.9	2.5	2.3	2.4	2.9	2.6	1.4	2.4	1.9	1.5	-1.0	1.2
Trunk fat-free mass	1.0	5.7	9.6	3.1	2.9	2.7	2.7	2.5	1.7	2.6	2.1	2.5	2.5	2.8	2.1	2.5	2.8	2.7	2.5	2.5	2.8	2.8	1.6	2.5	1.8	0.9	-1.6	0.6
Trunk predicted mass	1.0	5.8	9.5	3.1	2.9	2.7	2.8	2.5	1.7	2.6	2.1	2.5	2.5	2.8	2.1	2.5	2.8	2.7	2.5	2.5	2.8	2.8	1.6	2.5	1.9	0.9	-1.6	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	7.3	1.4	1.7	0.8	0.5	1.2	-0.8	1.4	-0.5	0.4	1.2	1.6	-0.2	1.3	1.0	1.1	1.2	1.2	0.6	1.7	1.2	1.0	-0.3	-1.2	-2.7	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.6	0.9	1.5	1.0	0.7	1.3	-0.1	1.3	-0.2	0.7	1.3	1.6	1.1	1.2	0.8	1.1	1.3	1.3	0.6	1.6	1.6	1.2	0.3	-0.5	-1.2	-0.8
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.3	-0.9	-1.3	-1.2	-0.9	-1.5	-0.4	-1.4	-0.0	-0.7	-1.5	-0.6	-0.3	-1.4	-0.8	-1.4	-1.5	-1.5	-0.7	-1.1	-1.1	-1.3	-0.9	0.7	1.0	1.3
Long-standing illness, disability or infirmity	1.0	1.5	5.8	1.4	1.9	0.8	0.1	1.3	-1.1	1.5	-0.3	0.3	1.3	1.8	-0.4	1.4	0.5	0.8	1.3	1.3	0.4	1.5	0.9	0.9	-0.4	-1.3	-2.4	-1.4
Myopia	1.0	1.5	3.1	-0.7	-0.9	-1.1	-1.1	-1.7	-0.7	-1.6	-0.4	-1.1	-1.8	-0.9	-0.1	-1.7	-0.7	-1.5	-1.8	-1.7	-0.6	-1.4	-1.3	-1.5	-1.3	0.4	0.8	1.1
Pack years of smoking	1.0	1.4	2.2	1.5	1.5	1.3	1.2	1.3	0.9	1.4	0.5	1.3	1.3	1.2	1.5	1.4	0.8	1.4	1.3	1.3	1.5	1.5	1.1	1.2	0.7	0.4	-1.1	-0.2
Prostate Cancer	0.9	1.3	3.1	0.5	1.2	0.9	0.5	1.5	-0.1	1.3	-0.2	0.8	1.5	1.8	0.4	1.3	1.4	1.1	1.5	1.5	0.5	1.6	1.2	1.3	0.1	-0.7	-1.6	-1.0
Crohns Disease (2012)	0.9	1.5	3.6	1.1	0.7	1.1	1.4	0.9	1.5	0.9	1.9	1.7	0.9	0.7	1.5	0.9	1.4	1.0	0.9	0.9	1.2	1.0	1.5	1.2	1.5	1.9	0.8	1.0
Hearing difficulty/problems: Yes	0.9	1.3	2.6	1.3	1.4	1.1	0.9	1.3	0.2	1.3	1.1	1.4	1.3	1.6	0.9	1.3	1.3	0.9	1.3	1.3	1.0	1.6	1.1	1.3	0.5	0.6	-0.3	0.8
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	3.8	-0.4	-0.0	-1.0	-1.4	-0.7	-2.0	-0.6	-1.7	-1.4	-0.7	-0.1	-1.1	-0.6	-0.6	-0.9	-0.7	-0.7	-1.1	-0.4	-1.2	-1.0	-1.8	-1.6	-1.2	-0.6
Taking other prescription medications	0.9	1.3	3.5	1.9	1.8	1.0	0.6	1.1	-0.5	1.3	0.3	0.9	1.1	1.8	1.0	1.3	1.2	0.9	1.1	1.1	0.9	1.6	1.1	1.0	-0.1	-0.0	-1.8	-0.3
Serious illness, injury or assault to yourself	0.9	1.1	4.9	-0.4	0.2	-0.9	-1.2	-0.7	-1.6	-0.6	-1.2	-1.0	-0.7	-0.7	-2.1	-0.7	-1.0	-0.8	-0.7	-0.7	-0.7	-0.8	-2.2	-1.0	-1.7	-1.0	-0.8	0.3
Medication: Levothyroxine sodium	0.9	1.6	9.8	0.5	1.2	0.1	-0.5	0.9	-1.4	0.9	-1.8	-0.7	0.8	1.1	-0.9	0.9	0.3	0.7	0.8	0.8	0.0	0.7	-0.7	-0.1	-1.5	-2.6	-3.1	-2.3
Neuroticism score	0.9	2.0	5.7	1.7	2.1	1.1	0.9	1.6	-0.5	1.8	0.3	1.0	1.6	2.4	1.0	1.7	1.2	1.3	1.6	1.6	0.7	2.0	1.3	1.4	-0.0	-0.6	-1.8	-0.5
Falls in the last year	0.9	1.3	5.1	-0.4	-0.8	-0.9	-0.5	-1.6	-0.1	-1.4	0.4	-0.3	-1.6	-0.7	-0.1	-1.5	-0.9	-1.3	-1.6	-1.6	-0.1	-0.8	-1.0	-1.3	-0.6	1.4	1.2	2.3
Prospective memory result	0.9	1.2	2.7	1.4	1.2	1.2	1.0	1.1	0.8	1.1	0.5	0.6	1.0	1.0	1.4	1.1	0.7	1.3	1.0	1.0	1.3	1.2	1.2	0.7	0.9	-0.3	-1.6	-1.3
Illnesses of mother	0.9	1.1	1.8	-1.1	-1.0	-1.2	-1.2	-1.0	-1.1	-1.0	-1.3	-1.1	-1.0	-1.2	-1.4	-1.0	-1.0	-1.2	-1.0	-1.0	-1.3	-1.2	-0.9	-1.1	-0.8	-0.4	0.6	-0.0
Suffer from ‘nerves’	0.9	1.5	10.1	0.7	1.2	0.2	-0.2	0.7	-1.7	0.9	-1.4	-0.3	0.8	1.5	0.5	0.8	-0.8	0.6	0.8	0.7	-0.2	1.1	0.5	0.3	-1.4	-1.9	-3.2	-2.2
Family relationship satisfaction	0.9	1.1	6.1	-0.6	-0.2	-0.8	-1.7	-0.6	-1.6	-0.4	-2.5	-1.5	-0.5	-0.3	-0.9	-0.4	-0.1	-1.0	-0.5	-0.5	-1.5	-0.3	0.2	-0.7	-1.2	-1.9	-0.5	-1.2
Mood swings	0.9	1.7	4.9	1.3	1.8	0.9	0.7	1.5	-0.6	1.6	0.1	1.1	1.5	2.2	0.6	1.5	1.1	1.0	1.5	1.5	0.5	2.0	1.8	1.4	0.2	-0.3	-1.4	-0.4
Medication for cholesterol	0.9	1.3	3.7	-1.9	-1.2	-1.3	-1.0	-0.8	-0.7	-1.1	-1.3	-1.0	-0.8	-1.4	-1.8	-1.2	-1.1	-0.9	-0.8	-0.8	-1.2	-1.4	-1.8	-1.1	-0.7	-0.5	0.8	0.2
Osteoporosis (self-reported)	0.9	1.2	2.7	1.5	1.6	1.1	1.0	1.1	0.4	1.2	0.3	0.7	1.1	1.4	1.5	1.2	1.4	1.2	1.1	1.1	1.1	1.1	0.6	1.0	0.5	-0.3	-1.2	-0.5
Average weekly champagne plus white wine intake	0.9	1.2	2.7	-1.2	-1.1	-1.4	-1.4	-0.8	-1.5	-0.9	-1.5	-1.6	-0.9	-0.7	-0.6	-0.8	-0.6	-1.1	-0.9	-0.9	-1.6	-0.7	-0.6	-1.2	-1.2	-1.6	0.3	-0.3
Neuroticism (Nagel 2018)	0.8	1.8	5.8	1.5	2.1	0.9	0.6	1.5	-0.9	1.7	-0.0	0.9	1.6	2.4	0.7	1.6	0.6	1.1	1.6	1.6	0.5	2.0	1.3	1.4	-0.3	-0.8	-2.0	-0.7
Alzheimer’s Disease (in father)	0.8	0.9	2.8	-0.9	-0.3	-0.9	-1.1	-0.5	-1.4	-0.5	-1.2	-1.2	-0.5	-0.8	-1.2	-0.6	-0.9	-0.7	-0.5	-0.5	-1.1	-0.8	-1.4	-0.9	-1.2	-1.7	-0.4	-0.7
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.2	1.4	0.3	1.1	1.4	0.7	1.5	0.8	2.0	1.5	0.7	0.7	1.9	0.9	1.7	0.8	0.7	0.7	1.3	0.9	1.4	1.1	1.6	1.9	0.4	0.8
Neuroticism	0.8	1.9	7.8	1.3	2.0	0.6	0.2	1.4	-1.5	1.6	-0.8	0.3	1.4	2.3	0.2	1.5	0.3	1.0	1.4	1.4	0.2	1.9	0.8	1.1	-0.9	-1.6	-2.8	-1.2
Current tobacco smoking	0.8	1.3	2.3	0.9	1.3	1.0	0.9	1.4	0.1	1.4	0.4	1.1	1.4	1.5	1.4	1.3	0.9	1.1	1.4	1.4	0.8	1.5	1.3	1.2	0.6	-0.1	-1.2	-0.6
Fluid intelligence score	0.8	1.6	5.1	-1.6	-1.7	-1.5	-1.3	-1.1	-0.6	-1.2	-0.3	-0.7	-1.1	-1.8	-1.2	-1.1	-0.5	-1.5	-1.1	-1.0	-1.4	-1.3	-1.2	-1.0	-0.7	0.3	2.2	1.7
Leg fat-free mass (right)	0.8	4.4	7.5	2.7	2.5	2.3	2.4	2.1	1.6	2.2	2.0	2.4	2.1	2.4	1.7	2.2	2.7	2.2	2.1	2.1	2.4	2.4	1.4	2.2	1.7	1.3	-0.8	1.1
Leg predicted mass (right)	0.8	4.3	7.4	2.7	2.5	2.3	2.3	2.1	1.6	2.2	1.9	2.3	2.1	2.4	1.7	2.2	2.7	2.2	2.1	2.1	2.4	2.4	1.4	2.1	1.7	1.2	-0.8	1.0
Depression (Nagel 2018)	0.7	1.1	3.4	1.6	1.5	0.9	0.8	0.9	-0.1	1.2	0.5	1.0	1.0	1.8	0.9	1.2	0.9	0.8	1.0	1.0	0.9	1.6	1.0	1.0	-0.0	0.3	-1.0	0.4
Alzheimer’s Disease (including proxy)	0.7	1.0	2.3	-1.3	-0.8	-1.1	-1.4	-0.7	-1.4	-0.8	-1.5	-1.3	-0.7	-0.8	-0.8	-0.8	-1.1	-1.1	-0.7	-0.7	-1.5	-0.7	-0.3	-0.9	-1.1	-1.4	0.1	-0.8
Ulcerative Colitis (UC)	0.7	1.3	4.5	0.6	0.5	1.1	1.2	0.5	2.1	0.3	1.8	1.2	0.4	0.4	1.9	0.3	2.0	0.8	0.4	0.5	1.6	0.5	1.2	0.7	1.5	1.6	0.8	0.4
Age at First Birth	0.7	1.0	4.7	-1.1	-1.1	-0.6	-0.3	-1.0	0.6	-1.1	-0.7	-0.7	-1.0	-1.7	-1.0	-1.1	-0.9	-0.5	-1.0	-1.0	-0.3	-1.7	-2.2	-0.8	-0.2	0.1	0.8	0.3
Ulcerative Colitis	0.7	1.1	3.7	0.7	0.6	1.0	1.1	0.5	1.7	0.4	1.5	1.0	0.4	0.8	1.9	0.4	1.5	0.7	0.4	0.4	1.3	0.6	1.4	0.7	1.5	1.4	-0.8	-0.3
Angina	0.7	0.9	3.5	0.9	1.0	0.9	0.5	0.9	-0.0	1.0	-0.1	0.4	1.0	1.2	1.1	1.0	1.0	0.7	1.0	0.9	0.5	1.4	1.9	1.0	0.7	-0.5	-1.0	-1.0
Average weekly fortified wine intake	0.7	0.8	2.3	-0.6	-0.2	-0.7	-0.9	-0.7	-1.1	-0.7	-1.1	-1.2	-0.7	-0.8	-1.3	-0.8	-0.7	-0.5	-0.7	-0.7	-0.6	-0.8	-1.5	-0.9	-1.3	-1.3	-1.0	-0.6
Maternal smoking around birth	0.7	0.9	3.5	1.0	1.2	0.7	0.9	0.8	0.2	0.8	0.9	1.4	0.8	1.9	1.3	0.7	0.7	0.6	0.8	0.7	0.8	1.4	1.3	0.8	0.6	1.3	-0.2	1.1
Supplements: Glucosamine	0.7	0.9	1.8	-0.8	-0.7	-0.8	-1.1	-0.9	-0.7	-0.9	-1.3	-0.9	-0.9	-0.8	-1.3	-0.9	-1.2	-1.1	-0.9	-1.0	-1.0	-1.0	-1.3	-1.0	-0.9	-0.3	1.1	1.1
Qualifications: None of the above	0.7	1.6	5.5	1.3	1.1	1.5	1.3	0.6	1.4	0.7	1.4	1.4	0.7	1.7	1.7	0.6	1.1	1.0	0.7	0.6	1.9	1.4	2.3	1.0	1.0	1.6	-0.1	0.4
Breastfed as a baby	0.7	0.9	2.6	-1.3	-1.3	-1.0	-0.4	-0.9	0.3	-1.2	0.7	-0.1	-1.0	-1.2	0.5	-1.2	-0.2	-1.0	-1.0	-1.0	-0.5	-1.0	-0.5	-0.8	0.1	1.3	1.6	1.2
Worry too long after embarrassment	0.7	1.1	2.0	-1.3	-1.1	-1.4	-1.1	-1.0	-1.4	-1.1	-1.2	-1.3	-1.0	-0.8	-0.4	-1.0	-0.9	-1.1	-1.0	-1.0	-1.4	-0.8	-0.7	-1.3	-1.2	-1.0	-0.0	-0.3
Had major operations	0.7	0.9	2.7	0.6	0.6	0.8	0.6	1.2	0.2	1.1	-0.5	0.4	1.2	0.7	0.2	1.2	1.1	1.2	1.2	1.2	0.4	0.7	0.3	0.9	0.7	-0.9	-1.5	-1.6
Eye problems/disorders: Glaucoma	0.7	0.9	2.1	0.9	0.8	0.9	0.8	1.1	0.2	1.2	0.1	1.0	1.2	1.5	0.5	1.2	0.6	0.8	1.2	1.1	0.6	1.4	1.3	1.1	0.8	0.3	-0.4	0.1
Medication: Paracetamol	0.7	1.1	2.5	1.2	1.1	1.0	1.0	0.8	0.7	0.9	1.0	1.1	0.9	1.4	1.5	0.9	1.2	0.9	0.9	0.9	1.1	1.4	1.6	1.1	0.6	0.8	-0.2	0.6
Unable to work because of sickness or disability	0.7	0.8	2.3	1.1	1.4	1.0	0.5	0.8	-0.1	1.0	-0.3	0.7	0.9	1.0	0.7	0.9	0.8	0.8	0.9	1.0	0.8	1.4	1.4	1.0	0.2	-0.1	-1.5	-0.8
Worry (Nagel 2018)	0.6	1.3	7.6	0.8	1.2	0.4	0.2	1.0	-1.2	1.1	-0.7	0.1	1.0	1.5	0.2	1.1	-0.4	0.9	1.0	1.0	0.1	1.2	0.5	0.7	-0.9	-1.6	-2.8	-2.0
Breast Cancer	0.6	1.4	2.9	0.9	1.0	1.2	1.1	1.5	1.2	1.4	0.5	1.3	1.4	1.3	0.9	1.4	1.3	1.2	1.4	1.4	0.9	1.1	1.5	1.4	1.7	0.5	0.1	-0.3
Number of treatments/medications taken	0.6	1.0	3.1	1.3	1.5	1.0	0.4	0.9	-0.1	1.1	0.6	0.8	1.0	1.2	1.3	1.1	1.0	0.8	1.0	0.9	0.8	1.5	1.8	1.0	0.2	-0.0	-1.2	-0.6
Impedance of leg (right)	0.6	2.9	6.5	-2.3	-2.0	-1.6	-1.6	-1.5	-1.0	-1.7	-1.2	-1.7	-1.5	-2.2	-2.4	-1.7	-2.1	-1.6	-1.5	-1.5	-1.7	-2.4	-2.5	-1.5	-1.4	-0.8	1.2	-0.1
Impedance of leg (left)	0.6	2.7	6.4	-2.5	-2.1	-1.7	-1.7	-1.3	-1.0	-1.6	-1.4	-1.7	-1.3	-2.1	-2.2	-1.5	-1.8	-1.5	-1.3	-1.3	-2.0	-2.2	-2.1	-1.4	-1.2	-1.1	1.3	-0.5
Number of live births	0.6	0.9	3.1	-1.1	-0.7	-1.2	-1.2	-0.6	-1.8	-0.6	-1.1	-0.8	-0.6	-0.9	-1.1	-0.6	-0.9	-1.0	-0.6	-0.6	-1.4	-0.5	-0.6	-0.9	-1.2	-0.6	-0.3	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.5	0.0	0.5	0.3	0.3	0.9	-0.3	0.7	-0.2	-0.1	0.9	0.8	-0.1	0.7	-0.0	0.9	0.9	0.9	0.0	0.7	0.3	0.5	0.0	-1.5	-1.9	-1.8
Length of working week for main job	0.6	0.7	1.2	0.8	0.7	0.9	0.8	0.8	0.8	0.8	0.9	1.1	0.9	0.8	0.8	0.8	0.9	0.8	0.9	0.9	0.8	0.9	1.1	1.0	0.9	0.8	-0.0	0.1
Number of full brothers	0.6	0.8	4.5	-0.7	-0.0	-0.5	-0.9	-0.3	-1.1	-0.3	-1.5	-1.2	-0.3	-0.1	-0.5	-0.4	-0.2	-0.3	-0.3	-0.2	-0.9	-0.1	0.4	-0.4	-0.7	-1.9	-1.4	-2.1
Health satisfaction	0.6	0.8	3.5	-0.4	0.0	-0.6	-1.2	-0.3	-1.4	-0.2	-1.8	-0.9	-0.3	-0.4	-1.9	-0.2	-1.1	-0.5	-0.3	-0.3	-1.0	-0.5	-1.2	-0.4	-1.2	-1.3	-0.9	-0.8
Angina (self-reported)	0.6	0.8	2.7	0.7	1.0	0.8	0.3	0.9	-0.3	1.0	-0.4	0.3	1.0	1.1	0.8	1.0	0.8	0.7	1.0	1.0	0.3	1.3	1.6	0.9	0.4	-0.8	-1.2	-1.2
Age at last live birth	0.6	0.9	2.4	-1.4	-1.2	-0.9	-1.0	-0.7	-0.5	-0.8	-0.9	-1.1	-0.7	-1.4	-1.6	-0.8	-1.0	-0.8	-0.7	-0.6	-1.1	-1.1	-1.1	-0.8	-0.6	-1.0	0.6	-0.4
Alzheimer’s Disease (in mother)	0.5	0.6	1.1	-1.1	-1.0	-0.8	-0.9	-0.7	-0.8	-0.8	-1.1	-0.9	-0.7	-0.6	0.2	-0.8	-0.8	-0.8	-0.7	-0.7	-1.0	-0.4	0.4	-0.7	-0.7	-0.5	0.2	-0.6
Irritable Bowel Disease (IBD)	0.5	1.2	5.4	0.3	-0.1	0.8	1.0	0.1	2.2	-0.1	1.8	1.3	0.0	-0.3	1.3	-0.1	1.5	0.4	0.0	0.1	1.2	0.0	1.0	0.5	1.6	2.3	1.8	1.3
Verbal and Numeric Reasoning (VNR)	0.5	1.1	4.8	-0.9	-1.3	-0.9	-0.7	-1.1	0.2	-1.1	0.6	-0.3	-1.1	-1.4	-0.5	-1.1	0.1	-1.2	-1.1	-1.1	-0.6	-1.2	-0.9	-0.8	-0.1	1.0	2.2	1.9
Ovarian Cancer	0.5	0.6	2.5	-0.2	-0.1	0.4	0.8	0.6	1.3	0.4	1.4	1.1	0.6	-0.2	-0.2	0.4	0.2	0.5	0.6	0.6	0.4	0.2	0.9	0.7	1.6	1.3	1.2	0.5
Lupus	0.5	0.7	4.8	0.1	0.7	-0.1	-0.7	0.3	-1.5	0.3	-0.8	-0.6	0.3	0.5	-0.5	0.2	-0.3	0.1	0.3	0.3	-0.3	0.3	-0.6	-0.1	-1.4	-1.7	-2.2	-1.5
Chronotype (morning person)	0.5	1.1	2.7	-0.9	-1.0	-1.1	-1.2	-1.0	-1.4	-0.9	-1.0	-1.0	-0.9	-1.1	-1.4	-0.8	-1.0	-1.1	-0.9	-0.9	-1.1	-0.9	-1.5	-1.1	-1.6	-0.6	-0.2	0.1
Multivitamins +/- minerals	0.5	0.7	2.1	-1.1	-0.9	-0.8	-1.0	-0.5	-0.9	-0.6	-1.0	-1.2	-0.5	-0.6	-0.1	-0.5	-0.8	-0.7	-0.5	-0.5	-1.2	-0.3	0.7	-0.6	-0.6	-1.3	-0.3	-1.4
Pain all over the body in last month	0.5	0.5	1.2	0.8	1.1	0.7	0.5	0.9	0.0	0.9	0.5	0.6	0.9	0.9	0.2	0.9	0.2	0.7	0.9	0.8	0.7	0.7	0.2	0.7	0.1	-0.1	-1.1	-0.6
Pulse wave Arterial Stiffness index	0.5	0.6	3.9	0.3	-0.2	0.5	0.6	-0.1	1.2	-0.2	1.0	0.9	-0.2	-0.2	1.3	-0.2	0.3	0.1	-0.2	-0.1	0.7	-0.2	0.2	0.3	0.9	2.0	1.2	1.2
Peak expiratory flow (PEF)	0.5	1.1	4.9	0.7	0.6	1.0	0.8	1.1	0.6	1.0	0.4	0.1	1.1	0.4	1.5	1.1	1.1	1.4	1.1	1.1	0.5	0.5	-0.0	0.9	0.1	-1.3	-1.9	-2.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.6	-1.2	-1.5	-1.0	-1.0	-0.6	-0.2	-0.8	-0.9	-0.5	-0.7	-1.2	-1.1	-0.6	-0.4	-1.0	-0.7	-0.6	-1.3	-1.0	-0.9	-0.7	-0.0	0.1	1.6	0.8
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	3.4	1.0	1.1	0.7	0.5	0.5	0.3	0.6	0.2	0.6	0.5	1.4	1.9	0.5	1.1	0.5	0.5	0.5	0.9	1.2	1.3	0.5	0.2	0.3	-0.7	0.2
Medication: Paracetamol	0.5	0.8	2.8	1.0	0.8	0.9	0.9	0.7	0.6	0.8	0.8	1.0	0.7	1.2	1.3	0.7	1.2	0.7	0.7	0.7	0.9	1.2	1.7	0.9	0.7	0.8	-0.1	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	2.4	0.2	0.9	0.7	0.5	0.6	0.6	0.5	-0.5	0.1	0.6	0.4	1.5	0.4	-0.0	0.9	0.6	0.6	0.8	0.5	0.6	0.3	0.4	-0.7	-1.3	-1.6
Pulse wave peak to peak time	0.5	0.6	4.3	-0.3	0.2	-0.5	-0.6	0.1	-1.2	0.2	-1.0	-1.0	0.2	0.0	-1.5	0.2	-0.3	-0.0	0.2	0.1	-0.8	0.1	-0.4	-0.3	-1.0	-2.1	-1.2	-1.1
Shortness of breath walking on level ground	0.5	0.6	2.1	0.6	1.1	0.4	0.2	0.9	-0.4	0.9	-0.9	0.1	0.9	0.9	-0.4	0.9	0.4	0.7	0.9	0.9	0.2	0.7	0.5	0.7	0.1	-1.0	-1.5	-1.3
Medication for pain relief, constipation, heartburn	0.5	0.9	2.8	-1.0	-0.7	-1.0	-1.0	-0.9	-0.9	-0.9	-0.6	-0.9	-0.9	-0.7	-0.6	-1.0	-1.1	-0.9	-0.9	-0.9	-0.9	-1.0	-1.7	-1.0	-1.3	-0.6	0.3	0.5
Medication: Omeprazole	0.5	0.7	1.5	-0.3	-0.3	-0.8	-1.1	-0.9	-1.2	-0.7	-1.0	-0.9	-0.9	-0.3	-1.1	-0.7	-0.8	-1.0	-0.9	-0.9	-0.9	-0.6	-0.6	-0.8	-1.0	-0.6	-0.6	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.0	-0.7	-0.7	-0.9	-0.7	-1.0	-0.5	-1.0	-0.7	-0.9	-1.0	-0.8	0.3	-1.0	-0.4	-0.8	-1.0	-0.9	-0.5	-0.4	0.2	-0.9	-0.5	-0.3	0.7	0.3
Commuting to job workplace: Walk	0.5	0.5	1.0	-0.9	-0.7	-1.0	-0.6	-0.9	-0.7	-1.0	-1.0	-0.7	-0.9	-0.5	-0.3	-1.0	-0.3	-0.9	-0.9	-0.9	-0.7	-0.6	-0.5	-0.9	-0.6	-0.0	0.3	0.5
Eye problems/disorders: Cataract	0.5	0.5	2.0	0.8	0.6	0.5	1.0	0.7	0.4	0.7	-0.0	1.1	0.7	0.8	-0.1	0.7	0.1	0.5	0.7	0.7	0.4	0.6	-0.0	0.8	1.1	1.0	0.7	1.4
Back pain experienced in last month	0.5	0.7	1.2	0.9	0.8	0.8	0.9	0.7	0.8	0.7	0.6	1.1	0.7	1.0	0.9	0.7	0.8	0.7	0.7	0.7	0.8	0.9	1.1	0.8	0.9	1.0	0.2	0.6
Breast cancer (self-reported)	0.5	0.6	1.9	-0.3	-0.3	-0.7	-0.8	-0.6	-1.1	-0.5	-1.1	-0.6	-0.7	-0.8	-1.4	-0.6	-1.1	-0.7	-0.7	-0.7	-0.6	-0.7	-1.3	-1.0	-0.7	-0.4	-0.0	0.6
Medication: Blood pressure	0.5	1.0	3.3	1.5	1.0	1.0	0.9	0.4	0.9	0.6	1.6	1.0	0.4	1.3	1.7	0.5	0.9	0.7	0.4	0.4	1.4	1.3	1.8	0.7	0.7	1.2	-0.3	0.5
Number of operations (self-reported)	0.5	0.7	3.5	-0.6	-0.2	-0.5	-0.7	0.3	-1.4	0.2	-1.6	-0.8	0.2	-0.5	-0.6	0.3	0.1	0.1	0.2	0.3	-0.9	-0.1	-0.3	-0.3	-0.8	-1.7	-1.4	-1.9
Supplements: Calcium	0.5	0.5	1.3	-0.8	-0.5	-0.7	-0.6	-0.8	-0.3	-0.9	0.2	-0.6	-0.9	-1.2	0.4	-0.9	-0.5	-0.7	-0.9	-0.8	-0.4	-1.0	-1.1	-0.8	-0.6	-0.0	0.3	0.2
HDL Cholesterol	0.4	0.7	2.6	0.6	0.0	0.6	0.7	0.4	1.3	0.4	1.4	1.1	0.3	-0.0	0.5	0.5	0.9	0.2	0.3	0.4	0.6	0.0	-0.0	0.5	1.2	1.6	1.6	1.5
Systolic blood pressure, automated reading	0.4	1.3	6.5	0.5	0.2	0.4	0.9	-0.0	1.2	-0.0	2.2	1.4	-0.0	0.8	1.6	-0.1	0.6	-0.1	-0.0	-0.1	1.1	0.5	1.1	0.2	1.0	2.6	1.7	2.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.9	1.0	1.0	0.7	0.7	0.7	0.2	0.8	0.3	0.6	0.7	1.4	0.9	0.8	0.7	0.8	0.7	0.7	0.7	1.0	0.8	0.6	0.2	0.0	-0.9	-0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.5	-0.4	-0.7	-0.3	-0.1	-0.7	0.7	-0.8	0.8	-0.1	-0.8	-1.0	0.7	-0.8	-0.5	-0.4	-0.8	-0.7	0.2	-0.8	-0.7	-0.6	0.1	0.9	1.2	1.2
Father’s age at death	0.4	0.6	1.3	-0.9	-1.1	-0.8	-0.4	-0.7	0.1	-0.9	0.6	-0.4	-0.8	-0.8	0.6	-0.8	-0.7	-0.9	-0.8	-0.8	-0.7	-0.8	-0.6	-0.7	-0.3	0.5	1.1	0.9
Worrier / anxious feelings	0.4	0.8	3.4	-0.7	-0.3	-1.1	-1.0	-0.6	-1.8	-0.5	-1.1	-1.1	-0.5	-0.3	-1.2	-0.5	-1.1	-0.8	-0.5	-0.5	-1.2	-0.4	-0.9	-0.7	-1.5	-1.3	-0.5	-0.2
Asthma	0.4	0.7	1.7	-0.2	-0.5	-0.9	-0.8	-1.2	-0.6	-1.1	0.6	-0.3	-1.2	-0.1	-0.3	-1.1	-0.5	-1.1	-1.2	-1.3	-0.2	-0.4	-0.2	-1.2	-0.9	0.9	0.5	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	1.3	0.6	0.2	0.7	0.9	0.9	0.9	0.8	0.5	1.0	0.9	0.5	-0.1	0.8	1.1	0.7	0.9	0.9	0.6	0.7	0.7	0.8	1.1	0.7	0.3	0.3
Ever highly irritable/argumentative for 2 days	0.4	0.4	3.5	-0.3	0.4	-0.2	-0.5	0.3	-0.8	0.2	-1.3	-0.9	0.3	0.1	-0.5	0.2	0.1	-0.0	0.3	0.3	-0.8	-0.1	-0.2	0.1	-0.5	-1.9	-0.5	-1.4
Wheeze or whistling in the chest in last year	0.4	0.7	3.1	0.9	0.4	0.7	0.7	0.2	1.1	0.3	1.5	0.7	0.2	0.9	1.3	0.3	1.1	0.4	0.2	0.1	1.0	0.7	1.8	0.3	0.8	1.0	0.3	0.2
Neck or shoulder pain in last month	0.4	0.6	1.9	1.0	1.0	0.5	0.3	0.7	-0.6	0.9	0.3	0.5	0.7	1.2	0.5	0.9	1.0	0.3	0.7	0.7	-0.1	1.1	1.4	0.9	0.2	-0.1	-0.4	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.0	-0.9	-0.9	-0.9	-0.5	-0.9	-0.2	-1.0	-0.4	-0.2	-0.9	-0.5	-0.2	-1.0	0.4	-1.0	-0.9	-0.9	-0.8	-0.8	-0.2	-0.6	0.0	1.1	1.4	1.2
Asthma (self-reported)	0.4	0.8	2.0	-0.4	-0.6	-1.0	-1.0	-1.3	-0.7	-1.2	0.4	-0.5	-1.4	-0.2	-0.5	-1.2	-0.7	-1.3	-1.4	-1.4	-0.3	-0.5	-0.2	-1.4	-1.0	0.7	0.4	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	4.6	-0.5	-1.0	-0.5	-0.4	-1.0	0.5	-0.9	0.5	-0.8	-1.0	-1.9	-0.4	-0.9	-0.7	-0.6	-1.0	-1.0	-0.4	-1.7	-2.1	-0.8	-0.5	-0.0	1.0	0.4
Hearing aid user	0.4	0.5	1.5	0.8	1.1	0.7	0.5	0.7	0.1	0.8	-0.1	0.5	0.7	0.6	0.2	0.7	0.2	0.7	0.7	0.7	0.7	1.0	0.9	0.6	0.7	-0.2	-1.2	-0.7
Mother’s age at death	0.4	0.5	4.1	-0.2	-0.5	-0.1	0.3	0.1	0.6	-0.1	0.8	0.4	-0.0	-0.4	-0.6	0.0	0.5	-0.3	-0.0	0.0	-0.2	-0.5	-0.5	0.1	1.0	1.0	2.0	1.6
Risk taking	0.4	0.6	2.9	0.6	0.1	1.0	1.1	0.7	1.5	0.7	0.3	0.6	0.8	-0.4	-0.3	0.8	0.5	1.0	0.8	0.8	0.8	-0.1	0.2	1.0	1.7	0.3	0.7	-0.4
Primary Biliary Cirrhosis	0.3	0.4	1.2	-0.4	-0.2	-0.7	-0.6	-0.8	-0.8	-0.7	0.4	-0.4	-0.7	-0.1	-0.7	-0.7	-0.9	-0.7	-0.7	-0.7	-0.3	-0.2	-0.2	-0.6	-1.1	0.1	0.2	0.7
Blood Platelet Count	0.3	3.6	6.8	2.1	1.9	2.1	1.6	2.2	1.2	2.3	-0.7	1.4	2.2	1.8	1.3	2.4	1.5	2.5	2.2	2.1	1.6	1.9	1.8	1.9	1.4	-0.5	-2.6	-2.4
Blood Red Count	0.3	2.9	7.1	-1.5	-0.8	-1.9	-2.2	-1.7	-2.5	-1.6	-1.3	-1.7	-1.7	-0.6	-1.9	-1.8	-1.4	-2.1	-1.7	-1.7	-1.8	-1.3	-2.0	-1.9	-2.7	-0.9	0.2	1.0
Sensitivity / hurt feelings	0.3	0.5	1.3	1.1	0.9	0.4	0.4	0.4	-0.3	0.5	0.2	0.5	0.3	1.1	1.0	0.5	1.1	0.4	0.3	0.4	0.6	1.1	0.9	0.4	-0.2	0.4	-0.6	0.7
Ever had hysterectomy (womb removed)	0.3	0.4	1.7	-0.4	-0.1	-0.6	-0.8	-0.3	-1.3	-0.3	-0.9	-0.6	-0.3	-0.1	-1.1	-0.3	-0.3	-0.5	-0.3	-0.3	-0.6	-0.1	-0.5	-0.5	-1.1	-0.7	-0.6	-0.1
Severe depression (siblings)	0.3	0.4	1.7	0.4	0.7	-0.1	-0.3	0.2	-1.3	0.4	-0.7	-0.4	0.3	0.5	-1.1	0.3	-0.0	-0.0	0.3	0.3	-0.5	0.4	-0.3	0.3	-0.7	-1.2	-1.1	-0.4
Townsend deprivation index at recruitment	0.3	0.4	2.0	-0.2	0.6	-0.3	-0.6	-0.1	-1.3	-0.1	-1.0	-0.6	-0.1	0.8	-0.1	-0.2	0.5	-0.2	-0.1	-0.0	-0.1	0.6	0.6	-0.4	-0.9	-1.2	-1.4	-0.9
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.1	0.4	0.7	0.3	0.0	0.7	-0.8	0.7	-0.8	-0.1	0.6	0.7	-0.4	0.6	0.7	0.5	0.6	0.6	0.0	0.4	-0.4	0.4	-0.1	-1.0	-1.0	-0.8
Chronic bronchitis/emphysema (father)	0.3	0.4	2.1	0.2	0.8	0.1	-0.1	0.5	-0.9	0.5	-0.7	-0.1	0.5	1.0	-0.5	0.4	0.3	0.4	0.5	0.5	0.1	0.6	-0.1	0.3	-0.7	-0.9	-1.4	-0.7
Number of incorrect matches in round	0.3	0.5	2.1	-0.1	0.2	0.3	0.4	0.8	0.1	0.7	-0.5	0.2	0.8	0.4	0.8	0.8	0.5	0.7	0.8	0.8	0.1	0.7	1.1	0.7	0.5	-0.8	-0.7	-1.5
Nervous feelings	0.3	0.5	3.5	0.4	0.6	0.0	-0.1	0.5	-0.9	0.6	-0.9	-0.1	0.5	1.1	0.2	0.6	-0.4	0.4	0.5	0.5	-0.1	0.7	0.1	0.2	-0.9	-1.0	-1.9	-1.1
Diabetes (self-reported)	0.3	0.5	1.5	1.0	0.2	0.6	0.7	0.5	0.8	0.6	1.0	0.9	0.5	0.5	0.9	0.7	1.2	0.5	0.5	0.5	0.6	0.5	0.6	0.7	0.8	1.0	0.1	0.4
Standing height	0.3	3.0	15.8	-1.6	-2.0	-1.4	-0.9	-1.5	-0.1	-1.6	-0.1	-1.3	-1.6	-2.7	-2.4	-1.5	-1.1	-1.3	-1.6	-1.5	-1.2	-2.6	-4.0	-1.5	-1.0	-0.0	2.1	1.8
Blood clot in the leg (DVT)	0.3	0.4	1.1	-0.3	-0.7	-0.2	0.2	-0.9	1.0	-0.9	0.4	-0.2	-0.9	-0.7	0.4	-0.9	-0.6	-0.3	-0.9	-0.9	0.4	-0.7	-0.2	-0.6	0.5	0.9	0.5	0.2
Birth weight	0.3	0.6	2.1	0.3	0.3	0.9	0.9	0.9	1.4	0.8	0.2	0.4	0.9	-0.4	-0.7	0.8	0.4	1.2	0.9	0.9	0.7	-0.2	-0.6	1.0	1.3	-0.3	-0.1	-1.0
Medication: Allopurinol	0.3	0.3	1.9	0.1	-0.3	-0.4	-0.3	-0.6	-0.2	-0.4	0.6	-0.1	-0.6	-0.5	-0.9	-0.4	-0.6	-0.4	-0.6	-0.5	-0.0	-0.5	-0.9	-0.3	-0.5	0.6	0.9	1.4
Medication: Seretide 50 evohaler	0.3	0.3	2.0	0.2	-0.0	-0.2	0.1	-0.5	0.4	-0.4	0.4	0.4	-0.6	0.1	0.2	-0.5	0.1	-0.4	-0.6	-0.6	0.2	-0.3	-0.2	-0.3	0.4	1.3	1.0	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	2.7	0.7	0.5	0.2	0.2	0.1	-0.4	0.3	0.5	0.8	0.2	1.3	0.3	0.2	-0.0	-0.2	0.2	0.1	0.3	1.0	0.8	0.3	-0.2	1.1	0.1	1.6
Medication: Aspirin	0.3	0.5	2.0	0.4	0.4	0.5	0.4	0.7	0.4	0.8	-0.0	0.2	0.8	0.1	0.1	0.9	0.5	0.7	0.8	0.8	0.2	0.5	1.2	0.6	1.0	-0.6	-0.5	-1.4
Average weekly red wine intake	0.3	0.5	1.4	-0.0	0.2	0.6	0.6	1.1	0.8	0.9	-0.1	0.7	1.1	-0.3	0.3	1.0	0.5	0.9	1.1	1.1	-0.0	0.2	-0.3	0.9	1.2	-0.1	0.1	-0.5
Loneliness, isolation	0.3	0.4	1.8	0.7	0.8	0.2	0.1	0.5	-0.6	0.6	-0.2	0.5	0.5	1.4	0.4	0.6	0.9	0.1	0.5	0.5	-0.0	1.1	1.0	0.5	-0.2	0.1	-0.3	0.5
Diabetes diagnosed by doctor	0.3	0.5	2.0	0.5	-0.2	0.4	0.6	0.3	0.9	0.3	1.3	0.9	0.2	0.0	1.2	0.4	1.1	0.2	0.2	0.3	0.4	0.3	0.6	0.5	0.9	1.4	0.7	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	2.3	0.6	-0.0	0.3	0.5	-0.2	0.9	-0.0	1.5	0.1	-0.2	-0.2	1.4	-0.0	0.0	0.1	-0.2	-0.1	0.6	0.1	0.7	0.1	0.5	0.4	0.2	0.0
Medication: Aspirin	0.3	0.4	1.3	0.4	0.2	0.6	0.4	0.7	0.6	0.7	0.2	0.4	0.7	-0.0	0.3	0.8	0.6	0.7	0.7	0.7	0.2	0.5	1.1	0.7	1.0	-0.1	-0.1	-0.9
Illnesses of father: None of the above (group 1)	0.3	0.3	1.5	-0.4	-0.9	-0.3	-0.2	-0.6	0.6	-0.6	0.1	-0.2	-0.6	-0.9	0.5	-0.6	0.5	-0.5	-0.6	-0.6	-0.3	-0.6	0.6	-0.3	0.8	0.6	1.2	0.2
Number of self-reported non-cancer illnesses	0.3	0.6	3.6	0.1	0.5	-0.2	-0.8	0.1	-1.5	0.2	-0.9	-0.5	0.1	0.5	-0.3	0.2	0.1	-0.1	0.1	0.1	-0.5	0.4	0.3	-0.3	-1.4	-1.3	-1.9	-1.5
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	0.7	0.7	0.8	0.8	0.6	0.8	0.6	0.2	0.4	0.6	0.1	0.3	0.6	0.7	0.9	0.6	0.6	0.7	0.3	0.1	0.5	1.0	-0.1	-0.5	-0.7
Commuting to job workplace: Cycle	0.3	0.4	1.8	0.0	-0.2	-0.3	0.1	-0.6	0.4	-0.5	0.6	-0.1	-0.6	-0.5	-0.6	-0.6	-0.6	-0.4	-0.6	-0.6	0.1	-0.7	-1.1	-0.5	0.2	0.7	1.1	1.4
Cholesterol lowering medication	0.3	0.4	1.4	-0.1	-0.1	-0.5	-0.9	-0.5	-1.2	-0.3	-1.0	-0.8	-0.4	-0.2	0.3	-0.3	-0.3	-0.6	-0.4	-0.4	-0.8	-0.1	0.4	-0.6	-0.9	-0.9	-0.8	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.1	-0.2	-0.7	-0.2	0.3	-0.8	1.1	-0.8	0.4	-0.2	-0.9	-0.8	0.4	-0.8	-0.5	-0.2	-0.9	-0.9	0.4	-0.8	-0.2	-0.6	0.5	0.7	0.4	0.1
Heart disease (siblings)	0.3	0.4	1.5	-0.6	-0.2	-0.8	-0.9	-0.2	-1.2	-0.3	-1.0	-0.7	-0.2	0.0	-0.9	-0.3	-0.2	-0.6	-0.2	-0.2	-0.9	-0.1	-0.2	-0.4	-1.1	-0.9	-0.6	-0.6
Crohns Disease (2017)	0.2	0.4	2.8	-0.2	-0.7	0.1	0.3	-0.3	1.1	-0.4	0.8	0.7	-0.3	-0.8	0.2	-0.3	0.3	-0.2	-0.3	-0.3	0.3	-0.3	0.5	-0.0	0.8	1.7	1.4	1.1
HbA1C	0.2	0.2	1.4	0.0	-0.0	0.3	0.3	0.2	0.6	0.2	1.2	0.4	0.3	0.0	1.0	0.2	0.4	0.2	0.3	0.3	0.3	-0.0	0.1	0.3	0.1	0.4	0.4	0.2
Triglycerides	0.2	0.4	1.9	0.0	0.3	0.2	-0.2	0.3	-0.2	0.3	-0.8	-0.3	0.3	0.7	1.4	0.2	0.6	0.3	0.3	0.3	-0.2	0.7	1.3	0.2	-0.1	-0.9	-0.9	-1.3
Systolic Blood Pressure	0.2	1.2	5.4	0.5	0.1	0.3	0.9	-0.1	1.0	-0.1	1.9	1.2	-0.1	0.8	2.1	-0.1	0.8	-0.1	-0.1	-0.1	1.0	0.7	1.5	0.2	0.9	2.3	1.4	2.0
Lung FVC	0.2	0.8	2.3	0.8	1.3	1.1	1.0	0.9	0.9	0.8	0.1	0.2	0.8	0.3	1.4	0.7	0.8	1.3	0.8	0.8	1.1	0.4	-0.2	0.5	0.5	-0.8	-1.5	-1.5
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.3	0.9	0.7	0.5	0.3	0.6	-0.1	0.7	0.4	0.5	0.6	1.1	-0.3	0.8	0.4	0.5	0.6	0.6	0.5	0.8	0.3	0.5	-0.3	-0.1	-0.6	0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.0	0.4	0.4	-0.1	-0.2	-0.1	-0.7	0.0	-0.3	-0.1	-0.1	1.0	-0.0	-0.0	0.3	-0.2	-0.1	-0.1	-0.0	0.7	0.7	-0.2	-0.6	-0.2	-0.8	0.1
Vitamin and mineral supplements	0.2	0.3	2.0	0.1	-0.1	-0.0	0.3	-0.5	0.6	-0.4	0.6	0.5	-0.5	-0.2	0.5	-0.5	-0.3	-0.1	-0.5	-0.5	0.6	-0.2	-0.5	-0.3	0.1	1.4	0.5	1.4
Medication: Metformin	0.2	0.2	1.1	0.6	-0.4	0.3	0.3	0.0	0.7	0.1	0.8	0.5	-0.0	-0.2	0.9	0.3	0.4	0.1	-0.0	0.0	0.3	-0.0	0.6	0.1	0.7	1.1	0.4	0.1
Hand grip strength (right)	0.2	0.5	1.5	-0.6	-1.1	-0.4	-0.1	-0.8	0.7	-0.9	0.7	-0.5	-0.8	-1.2	-0.3	-0.8	-0.3	-0.5	-0.8	-0.8	-0.2	-1.2	-1.1	-0.6	0.3	0.3	1.0	0.3
Relative age voice broke	0.2	0.3	1.9	0.3	0.2	0.5	0.7	0.6	1.0	0.5	0.3	0.5	0.6	0.4	0.0	0.6	0.1	0.5	0.6	0.5	0.3	0.3	1.0	0.6	1.4	0.2	0.5	-0.3
Age when periods started (menarche)	0.2	0.4	2.4	-1.1	-0.6	-0.6	-0.4	-0.3	0.0	-0.4	0.6	-0.2	-0.2	-0.6	-1.1	-0.4	-0.7	-0.6	-0.2	-0.3	-0.7	-0.8	-1.0	-0.1	-0.3	0.0	1.5	0.8
Stomach or abdominal pain in last month	0.2	0.3	0.7	-0.1	-0.9	-0.6	-0.6	-0.7	-0.5	-0.6	-0.5	-0.6	-0.8	-0.3	0.2	-0.5	0.2	-0.7	-0.8	-0.7	-0.6	-0.5	-0.3	-0.7	-0.7	-0.1	0.1	-0.0
Hearing difficulty/problems with background noise	0.2	0.3	0.7	-0.0	-0.2	-0.5	-0.7	-0.6	-0.8	-0.4	-0.5	-0.4	-0.6	0.1	0.5	-0.5	0.5	-0.8	-0.6	-0.5	-0.6	-0.0	0.1	-0.5	-0.7	0.1	0.4	0.8
Hair/balding pattern: Pattern 2	0.2	0.3	1.6	0.2	0.1	0.2	0.6	-0.0	0.8	-0.1	0.8	0.5	-0.0	0.0	0.1	-0.1	-0.2	0.1	-0.0	-0.0	0.4	-0.2	-0.5	0.3	0.7	0.9	0.9	1.3
Allergy	0.2	0.5	2.7	-0.6	-0.4	-0.5	-0.7	0.0	-1.1	-0.0	-1.6	-0.7	0.1	0.0	-1.3	0.0	-0.6	-0.3	0.1	0.1	-1.1	-0.3	-0.7	-0.2	-0.7	-1.3	-0.5	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	5.9	-0.6	-0.8	-0.4	-0.4	-0.4	-0.0	-0.5	-0.1	-0.7	-0.4	-1.5	-1.2	-0.4	-0.7	-0.4	-0.4	-0.4	-0.7	-1.4	-2.4	-0.3	-0.6	-0.6	0.7	0.3
Birth weight of first child	0.2	0.3	1.8	0.2	0.5	0.4	0.3	0.5	-0.3	0.4	0.6	-0.1	0.5	0.1	-0.8	0.3	0.4	0.7	0.5	0.5	0.4	-0.0	-0.9	0.2	-0.1	-1.0	-1.3	-1.1
Headache pain in last month	0.2	0.3	1.2	-0.5	-0.4	-0.6	-0.8	-0.5	-1.1	-0.4	-0.7	-0.5	-0.4	0.0	-0.3	-0.4	-0.2	-0.7	-0.4	-0.4	-0.8	-0.1	0.3	-0.4	-0.7	-0.3	-0.2	-0.2
Glaucoma (self-reported)	0.2	0.2	1.1	-0.1	0.0	-0.3	-0.3	0.2	-1.1	0.3	-1.0	-0.2	0.3	0.5	-0.5	0.3	-0.6	-0.0	0.3	0.2	-0.7	0.4	0.2	0.0	-0.3	-0.8	-0.8	-0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.5	0.4	0.5	0.4	0.4	0.2	0.5	0.2	0.7	0.9	0.2	0.3	-0.8	0.1	0.6	0.1	0.2	0.2	0.6	0.3	0.4	0.4	0.7	1.2	0.5	0.8
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.3	-0.1	0.1	0.1	0.5	0.2	0.4	0.1	1.1	0.6	0.2	0.3	0.3	0.1	0.1	0.3	0.2	0.2	0.4	0.0	-0.4	0.1	0.1	0.8	0.5	0.9
Forced vital capacity (FVC), Best measure	0.2	0.6	6.7	-0.3	-0.4	-0.2	-0.1	-0.3	0.1	-0.3	-0.4	-0.6	-0.3	-1.3	-1.4	-0.2	-0.7	-0.0	-0.3	-0.3	-0.4	-1.3	-2.6	-0.3	-0.5	-0.7	0.2	0.1
Medication: Ibuprofen	0.2	0.2	0.4	0.3	-0.0	0.4	0.6	0.5	0.5	0.4	0.2	0.6	0.5	0.2	-0.4	0.5	0.6	0.4	0.5	0.5	0.3	0.3	0.2	0.5	0.7	0.5	0.4	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.7	-0.3	-0.1	-0.4	-0.4	-0.4	-0.6	-0.4	-0.4	-0.3	-0.4	-0.3	-0.8	-0.4	-0.8	-0.3	-0.4	-0.4	-0.2	-0.2	-0.5	-0.6	-0.5	-0.2	-0.9	-0.4
Comparative height size at age 10	0.2	1.0	6.8	-0.4	-0.6	-0.6	-0.7	-0.8	-0.4	-0.7	-0.8	-1.0	-0.8	-1.5	-1.8	-0.7	-0.5	-0.5	-0.8	-0.7	-0.4	-1.4	-2.6	-0.9	-1.1	-0.6	0.7	0.8
Chest pain or discomfort	0.2	0.3	1.5	0.7	0.6	0.5	0.3	0.3	0.3	0.4	0.3	0.4	0.4	0.8	1.1	0.4	0.8	0.3	0.4	0.4	0.4	0.8	1.2	0.4	0.4	0.1	-0.6	-0.5
Supplements: Vitamin C	0.2	0.2	0.8	0.4	0.5	0.1	-0.2	0.3	-0.9	0.4	-0.3	-0.2	0.3	0.7	-0.4	0.4	0.6	0.1	0.3	0.4	-0.2	0.1	-0.5	0.3	-0.5	-0.9	-0.4	-0.3
Ever had bowel cancer screening	0.2	0.3	0.9	-0.7	-0.4	-0.4	-0.5	-0.5	-0.1	-0.5	-0.9	-0.7	-0.5	-0.6	0.0	-0.5	-0.2	-0.2	-0.5	-0.5	-0.1	-0.3	0.1	-0.7	-0.6	-0.5	-0.5	-1.0
Medication: Gliclazide	0.2	0.2	1.3	0.1	-0.2	-0.2	-0.2	-0.5	0.1	-0.4	0.0	0.1	-0.5	-0.5	0.4	-0.4	-0.2	-0.7	-0.5	-0.5	-0.2	-0.5	-0.8	-0.2	-0.1	0.9	0.8	1.1
High cholesterol (Self-reported)	0.2	0.4	2.6	0.3	0.5	0.6	-0.1	0.5	-0.2	0.5	0.2	0.1	0.5	0.1	0.7	0.5	0.5	0.4	0.5	0.5	0.2	0.6	1.2	0.3	0.1	-0.5	-1.1	-1.6
Basal cell carcinoma (self-reported)	0.2	0.2	0.9	-0.9	-0.4	-0.6	-0.4	-0.2	-0.4	-0.3	-0.6	-0.6	-0.1	-0.6	-0.7	-0.3	-0.6	-0.2	-0.1	-0.1	-0.7	-0.1	-0.0	-0.1	-0.5	-0.8	-0.3	-0.6
LDL Cholesterol	0.1	0.1	1.1	0.0	-0.0	-0.0	0.1	-0.2	0.5	-0.3	-0.1	0.1	-0.3	0.5	1.1	-0.3	0.3	-0.1	-0.3	-0.3	0.0	0.1	0.7	-0.0	0.3	0.5	0.6	0.5
Neuroticism (2016)	0.1	0.2	0.7	0.8	0.6	0.5	0.3	0.3	-0.2	0.5	-0.2	0.4	0.4	0.6	-0.5	0.5	0.1	0.3	0.4	0.4	0.5	0.6	0.3	0.3	0.0	0.0	-0.5	0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	0.3	0.3	-0.1	0.1	-0.2	-0.1	-0.1	-0.2	0.0	-0.2	0.5	0.6	-0.2	0.6	-0.1	-0.2	-0.2	0.2	0.2	0.3	-0.0	-0.1	-0.6	-0.6	-0.3
Blood White Count	0.1	0.8	5.3	-0.6	-0.1	-1.2	-1.2	-0.6	-2.3	-0.5	-0.7	-0.4	-0.5	0.3	-1.2	-0.6	-0.6	-1.1	-0.5	-0.6	-1.1	0.1	-0.6	-0.8	-1.8	-0.3	-0.8	0.7
Heel T-Score	0.1	0.6	3.3	-0.5	0.0	-1.0	-0.8	-0.2	-1.8	-0.2	-0.3	-0.1	-0.2	0.7	-1.6	-0.3	-0.6	-0.9	-0.2	-0.3	-1.1	0.2	-0.5	-0.5	-1.0	-0.2	0.2	1.2
Waist Hip Ratio (WHR)	0.1	0.5	6.5	-0.3	-0.1	0.0	-0.2	-0.2	0.2	-0.1	-0.7	-0.8	-0.1	-0.7	0.3	-0.1	-0.3	0.4	-0.1	-0.1	-0.1	-0.4	0.2	-0.1	-0.1	-1.2	-1.6	-2.5
Allergy or Eczema	0.1	0.3	1.3	-0.6	-0.3	-0.4	-0.7	-0.4	-0.4	-0.3	-0.4	-0.9	-0.4	-1.1	-0.1	-0.3	-0.4	-0.3	-0.4	-0.3	-0.5	-0.4	0.1	-0.5	-0.4	-1.1	-0.3	-1.1
Respiratory disease	0.1	0.1	0.9	0.2	0.7	-0.1	-0.5	-0.2	-0.5	-0.1	-0.1	-0.1	-0.2	0.4	-0.2	-0.2	-0.1	-0.2	-0.2	-0.2	0.2	0.4	0.4	-0.3	-0.6	-0.2	-0.9	-0.2
Hair Pigment	0.1	4.1	7.3	2.1	2.5	1.9	1.3	2.7	-0.4	2.7	-0.3	1.5	2.7	2.5	0.4	2.7	2.0	2.0	2.7	2.7	1.2	2.5	2.0	2.4	1.2	-1.0	-2.1	-1.4
Hand grip strength (left)	0.1	0.2	0.9	0.1	-0.5	-0.2	0.4	-0.4	0.6	-0.4	0.6	-0.1	-0.4	-0.3	0.0	-0.3	0.1	-0.1	-0.4	-0.4	0.0	-0.6	-0.9	-0.1	0.2	0.4	0.4	0.6
Relative age of first facial hair	0.1	0.2	0.8	-0.1	0.3	0.3	0.2	0.5	0.4	0.4	-0.4	0.1	0.5	0.2	0.2	0.4	-0.0	0.4	0.5	0.5	0.0	0.3	0.9	0.5	0.7	-0.4	-0.1	-0.9
Supplements: Zinc	0.1	0.1	0.6	-0.2	-0.5	-0.3	0.2	-0.2	-0.1	-0.2	0.3	-0.1	-0.2	-0.1	0.1	-0.2	-0.1	-0.2	-0.2	-0.2	-0.3	-0.1	0.0	-0.0	0.2	0.2	0.8	0.7
Hayfever, allergic rhinitis or eczema	0.1	0.2	1.6	-0.0	0.1	0.1	0.2	-0.1	0.6	-0.1	1.3	0.1	-0.1	-0.5	1.1	-0.2	0.1	0.0	-0.1	-0.1	0.4	-0.0	0.5	0.0	0.4	0.5	0.5	0.2
Sitting height	0.1	0.5	1.8	0.8	0.3	0.9	1.1	0.6	1.4	0.6	0.9	0.5	0.6	-0.3	0.0	0.7	0.7	1.0	0.6	0.6	0.8	-0.2	-0.9	0.7	0.8	0.1	0.2	0.0
Had other major operations	0.1	0.1	0.5	-0.3	-0.4	-0.5	-0.3	-0.4	-0.5	-0.4	-0.7	-0.3	-0.4	-0.3	0.5	-0.4	0.4	-0.4	-0.4	-0.4	-0.4	0.0	0.4	-0.5	-0.1	0.0	0.2	0.3
Forced vital capacity (FVC)	0.1	0.5	3.6	0.3	0.3	0.3	0.1	0.4	-0.0	0.3	-0.7	-0.5	0.3	-0.5	-1.0	0.4	-0.1	0.6	0.3	0.3	-0.0	-0.5	-1.9	0.1	-0.4	-1.5	-1.1	-1.0
Time employed in main current job	0.1	0.2	1.3	0.4	0.6	0.4	0.4	-0.2	0.8	-0.1	0.1	0.1	-0.2	-0.1	0.5	-0.2	0.0	0.4	-0.2	-0.2	1.1	-0.1	-0.3	-0.1	-0.1	0.4	-0.2	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.7	0.5	0.8	0.1	0.1	0.3	-0.4	0.4	0.3	0.5	0.3	0.9	-0.2	0.3	0.7	-0.0	0.3	0.3	0.2	0.7	0.4	0.4	-0.3	0.3	-0.1	0.7
Hair/balding pattern: Pattern 3	0.1	0.1	0.5	-0.7	-0.4	-0.4	-0.1	-0.1	-0.1	-0.3	-0.6	-0.1	-0.2	0.2	0.7	-0.3	0.2	-0.1	-0.2	-0.2	-0.1	0.1	0.6	-0.3	-0.1	0.1	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	3.0	-0.1	-0.1	-0.0	-0.0	0.0	-0.1	0.0	-0.1	-0.4	0.0	-0.7	-0.6	0.0	-0.1	0.1	0.0	0.1	-0.3	-0.7	-1.7	0.0	-0.5	-0.8	-0.2	-0.2
Depression (self-reported)	0.1	0.1	0.8	0.3	0.4	-0.1	-0.2	0.0	-0.5	0.2	-0.7	-0.2	0.1	0.2	-0.4	0.2	-0.5	-0.0	0.1	0.0	-0.3	0.0	-0.3	0.1	-0.5	-0.5	-0.9	-0.6
Hair/balding pattern: Pattern 4	0.1	0.3	1.6	-0.1	0.3	-0.4	-0.6	0.1	-1.3	0.2	-0.5	-0.4	0.1	0.2	-0.3	0.2	-0.4	-0.2	0.1	0.2	-0.7	0.4	0.3	-0.1	-0.8	-1.0	-1.1	-0.9
Gout (self-reported)	0.1	0.1	1.1	-0.0	-0.4	-0.2	-0.5	-0.3	-0.4	-0.1	0.1	0.0	-0.2	-0.3	-1.1	-0.0	-0.4	-0.4	-0.2	-0.2	-0.4	-0.2	-0.4	-0.0	-0.3	0.3	0.7	0.6
Comparative body size at age 10	0.1	0.2	1.7	0.1	-0.3	-0.2	-0.0	-0.4	0.2	-0.4	0.1	0.2	-0.4	-0.2	-0.3	-0.4	0.1	-0.4	-0.4	-0.4	0.1	0.1	0.3	-0.3	0.4	0.9	0.9	1.3
Age at first live birth	0.1	0.2	1.3	-0.7	-0.6	-0.2	-0.2	0.2	0.1	0.0	-0.3	-0.1	0.2	-0.7	-1.2	0.1	-0.6	-0.0	0.2	0.2	-0.6	-0.4	-0.7	0.1	0.3	-0.3	0.9	0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	1.5	0.2	-0.1	0.1	-0.1	0.1	-0.2	0.2	-0.8	-0.4	0.1	-0.3	-0.6	0.3	-0.1	0.2	0.1	0.1	-0.4	-0.4	-0.4	0.2	0.1	-0.9	-0.5	-1.2
Illnesses of father: Heart disease	0.1	0.2	0.7	0.6	0.5	0.5	0.5	0.3	0.2	0.3	0.6	0.5	0.3	0.6	0.3	0.3	-0.3	0.6	0.3	0.3	0.8	0.5	0.1	0.2	-0.0	0.4	-0.5	0.3
Miserableness	0.1	0.2	0.9	0.5	0.6	-0.1	-0.4	0.1	-1.0	0.3	0.3	0.2	0.1	0.6	-0.6	0.2	0.2	-0.4	0.1	0.1	-0.4	0.3	-0.4	0.1	-0.7	0.1	0.1	1.0
Guilty feelings	0.1	0.2	0.7	0.2	0.5	-0.3	-0.3	0.1	-0.7	0.2	-0.7	-0.4	0.0	0.3	-0.3	0.1	0.3	-0.0	0.0	0.1	-0.4	-0.1	-0.9	0.0	-0.7	-0.9	-0.4	-0.0
Ever taken oral contraceptive pill	0.1	0.1	0.7	0.2	0.1	-0.1	0.1	0.3	-0.5	0.3	0.1	0.3	0.3	0.4	-0.3	0.3	0.3	-0.0	0.3	0.3	-0.2	0.4	-0.2	0.2	-0.1	0.0	0.3	0.8
Medication: Bendroflumethiazide	0.1	0.2	1.2	0.2	-0.4	-0.1	0.1	-0.3	0.5	-0.3	0.7	0.1	-0.3	-0.2	0.4	-0.2	0.0	-0.3	-0.3	-0.3	0.1	-0.2	0.3	-0.1	0.3	0.8	1.1	0.9
Medication: Atorvastatin	0.1	0.1	0.4	0.3	0.2	0.2	-0.2	-0.1	-0.0	-0.1	-0.5	-0.2	-0.1	-0.3	-0.3	-0.1	0.6	-0.0	-0.1	-0.1	0.3	-0.1	-0.6	-0.1	-0.3	-0.2	-0.5	-0.1
Irritability	0.1	0.2	0.8	0.1	0.4	-0.1	-0.2	0.4	-0.7	0.4	-0.1	0.2	0.4	0.9	0.4	0.4	0.5	0.1	0.4	0.4	-0.1	0.8	0.8	0.2	-0.6	-0.4	-0.5	-0.2
Fractured/broken bones in last 5 years	0.1	0.1	0.4	0.1	0.3	0.1	-0.1	-0.1	-0.1	-0.1	-0.3	-0.2	-0.1	0.3	0.6	-0.2	-0.0	0.0	-0.1	-0.1	0.3	0.1	0.2	-0.1	-0.3	-0.3	-0.6	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.3	0.1	0.1	-0.3	-0.4	-0.4	-0.3	-0.3	-0.3	-0.2	-0.4	0.1	-0.3	-0.3	-0.3	-0.5	-0.4	-0.4	-0.3	-0.1	0.2	-0.2	-0.2	0.2	0.0	0.1
Lung FEV1/FVC ratio	0.0	0.2	0.9	-0.6	-0.4	-0.1	-0.4	0.3	-0.4	0.3	-0.2	-0.1	0.4	-0.2	-0.0	0.4	0.3	-0.2	0.4	0.4	-0.9	-0.1	0.3	0.5	0.0	-0.3	0.6	-0.4
Tanning	0.0	0.2	0.7	0.4	0.3	0.1	0.7	-0.3	0.5	-0.3	0.5	0.1	-0.4	0.1	0.7	-0.4	-0.3	0.3	-0.4	-0.4	0.7	-0.2	-0.8	-0.4	0.1	0.5	-0.3	0.7
Lung cancer (father)	0.0	0.0	0.3	-0.0	-0.1	0.1	0.1	-0.1	0.3	-0.1	-0.4	-0.1	-0.1	-0.2	0.5	-0.1	0.4	0.1	-0.1	-0.0	0.2	-0.1	0.1	0.0	0.0	0.1	-0.3	-0.3

Hub : Genes

ACTR1B

Models

Trait associations