Best TWAS P=2.35e-17 · Best GWAS P=6.45e-19 conditioned to 0.265
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FER | 0.10 | 0.01 | enet | 34 | 0.04 | 4.6e-06 | -0.69 | -6.5 | 9.5e-11 | -0.20 | 0.21 | 0.32 | TRUE |
| 2 | GTEx | Artery Coronary | FER | 0.34 | 0.10 | lasso | 8 | 0.12 | 5.4e-05 | -4.06 | 5.4 | 5.7e-08 | 0.59 | 0.17 | 0.24 | FALSE |
| 3 | GTEx | Artery Tibial | FER | 0.14 | 0.06 | enet | 7 | 0.05 | 7.3e-05 | -4.06 | 5.8 | 6.2e-09 | 0.68 | 0.24 | 0.75 | TRUE |
| 4 | GTEx | Artery Tibial | EFNA5 | 0.17 | 0.04 | lasso | 9 | 0.07 | 6.0e-06 | 6.70 | -7.1 | 1.1e-12 | -0.05 | 0.39 | 0.59 | TRUE |
| 5 | GTEx | Lung | LINC01023 | 0.11 | 0.02 | enet | 16 | 0.01 | 9.3e-02 | -4.38 | -8.5 | 2.3e-17 | -0.44 | 0.09 | 0.25 | TRUE |