[Hub]/) : Traits : Impedance of arm (left) : ← →

chr5:126,897,060-128,694,216

Best TWAS P=2.28e-11 · Best GWAS P=6.87e-10 conditioned to 0.596

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FBN2 0.22 0.24 lasso 11 0.28 1.6e-34 -6.1 -6.1 1.1e-09 0.96 0.00 1.00 FALSE
2 METSIM Adipose FBN2 0.11 0.18 bslmm 564 0.18 1.3e-25 -6.1 -6.1 1.3e-09 0.99 0.00 1.00 FALSE
3 NTR Blood FBN2 0.03 0.02 lasso 7 0.01 5.3e-05 -6.1 -5.9 3.9e-09 0.99 0.00 1.00 FALSE
4 ROSMAP Brain Pre-frontal Cortex FBN2 0.08 0.08 enet 11 0.09 2.3e-11 -6.1 -5.8 7.1e-09 0.96 0.00 1.00 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma FBN2 0.02 0.03 lasso 4 0.02 1.0e-05 -5.7 -5.6 2.1e-08 0.98 0.00 1.00 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FBN2 0.18 0.20 lasso 6 0.24 3.7e-27 -6.1 -6.2 7.7e-10 0.97 0.00 1.00 FALSE
7 The Cancer Genome Atlas Liver Hepatocellular Carcinoma FBN2 0.24 0.24 lasso 4 0.28 1.5e-13 -6.1 -5.3 1.0e-07 0.97 0.00 1.00 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma FBN2 0.11 0.12 blup 159 0.14 2.2e-16 -4.4 -6.7 2.3e-11 0.89 0.02 0.98 TRUE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FBN2 0.03 0.02 lasso 2 0.02 4.5e-03 -5.7 -5.6 1.7e-08 0.98 0.01 0.97 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma FBN2 0.21 0.07 blup 159 0.10 4.2e-05 -5.7 -5.5 3.4e-08 0.89 0.02 0.98 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma FBN2 0.19 0.20 lasso 3 0.17 3.7e-07 -6.1 -5.9 3.8e-09 1.00 0.00 1.00 FALSE
12 The Cancer Genome Atlas Skin Cutaneous Melanoma FBN2 0.20 0.12 lasso 4 0.10 9.4e-04 -5.6 -5.4 5.6e-08 0.72 0.02 0.82 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma FBN2 0.09 0.04 blup 159 0.06 4.6e-05 -6.1 -5.3 1.3e-07 0.88 0.00 0.99 FALSE