[Hub]/) : Traits : Impedance of arm (left) :

chr1:77,655,651-79,300,939

Best TWAS P=3.64e-09 · Best GWAS P=1.83e-08 conditioned to 0.0601

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes NEXN 0.23 0.10 lasso 3 0.08 1.4e-03 5.3 5.5 3.5e-08 0.89 0.04 0.82 FALSE
2 GTEx Lung GIPC2 0.15 0.09 enet 17 0.12 2.5e-09 5.2 -5.4 7.5e-08 -0.81 0.08 0.91 FALSE
3 GTEx Nerve Tibial DNAJB4 0.08 0.07 lasso 3 0.07 1.3e-05 5.5 5.4 6.7e-08 0.98 0.02 0.98 FALSE
4 GTEx Spleen GIPC2 0.43 0.07 enet 19 0.22 2.9e-06 5.1 -5.6 2.0e-08 -0.85 0.07 0.92 FALSE
5 METSIM Adipose DNAJB4 0.04 0.04 lasso 4 0.03 2.1e-05 5.3 5.8 6.8e-09 0.68 0.04 0.94 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma DNAJB4 0.05 0.03 lasso 3 0.02 3.3e-03 4.8 5.3 1.2e-07 0.87 0.01 0.96 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma GIPC2 0.04 0.01 blup 65 0.00 2.5e-01 4.4 -5.9 3.6e-09 -0.74 0.02 0.67 TRUE
8 The Cancer Genome Atlas Brain Lower Grade Glioma GIPC2 0.02 0.02 lasso 3 0.02 1.0e-03 5.3 -5.3 1.4e-07 -0.73 0.03 0.92 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma DNAJB4 0.04 0.04 lasso 2 0.04 1.2e-05 -5.4 5.4 7.4e-08 0.29 0.00 0.99 FALSE