Best TWAS P=1.9e-08 · Best GWAS P=6.07e-12 conditioned to 1.22e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | GTEx | Esophagus Gastroesophageal Junction | MXD3 | 0.17 | 0.12 | lasso | 3 | 0.08 | 9.5e-04 | -5.0 | -5.6 | 1.9e-08 | 0.34 | 0.02 | 0.68 | TRUE |
| 4 | YFS | Blood | PRELID1 | 0.18 | 0.14 | enet | 18 | 0.18 | 4.0e-58 | -5.4 | 5.5 | 3.3e-08 | -0.39 | 0.92 | 0.08 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MXD3 | 0.04 | 0.02 | blup | 40 | 0.03 | 2.8e-04 | -5.0 | -5.5 | 4.3e-08 | 0.48 | 0.02 | 0.95 | FALSE |
| 6 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PRELID1 | 0.08 | 0.10 | lasso | 4 | 0.07 | 2.9e-04 | -5.4 | 5.4 | 6.0e-08 | -0.27 | 0.01 | 0.96 | FALSE |
| 3 | GTEx | Heart Left Ventricle | MXD3 | 0.17 | 0.03 | lasso | 3 | 0.03 | 1.5e-02 | -5.2 | -5.2 | 1.6e-07 | 0.31 | 0.02 | 0.85 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | PRELID1 | 0.33 | 0.08 | enet | 4 | 0.08 | 2.7e-05 | -5.0 | 5.2 | 2.1e-07 | -0.33 | 0.01 | 0.98 | FALSE |
| 1 | GTEx | Adipose Visceral Omentum | MXD3 | 0.33 | 0.06 | lasso | 6 | 0.05 | 9.1e-04 | -5.2 | -5.1 | 2.9e-07 | 0.32 | 0.02 | 0.92 | FALSE |