Best TWAS P=4.86e-11 · Best GWAS P=2.61e-11 conditioned to 0.158
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZNF354C | 0.09 | 0.03 | lasso | 3 | 0.01 | 0.1090 | 6.5 | 6.6 | 4.9e-11 | 0.94 | 0.02 | 0.97 | TRUE |
| 2 | GTEx | Artery Tibial | ZNF354C | 0.14 | 0.06 | lasso | 2 | 0.03 | 0.0022 | 6.4 | 6.4 | 1.2e-10 | 1.00 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Thyroid | ZNF354C | 0.09 | 0.00 | lasso | 4 | 0.00 | 0.8360 | 6.4 | 6.1 | 1.0e-09 | 0.98 | 0.02 | 0.85 | FALSE |