Best TWAS P=2.37e-11 · Best GWAS P=2.75e-10 conditioned to 0.000104
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | POC1B | 0.12 | 0.08 | lasso | 9 | 0.09 | 1.7e-07 | 5.0 | -5.2 | 2.0e-07 | -0.37 | 0.84 | 0.14 | FALSE |
| 2 | GTEx | Artery Tibial | POC1B | 0.13 | 0.06 | enet | 29 | 0.06 | 1.7e-05 | 4.9 | -6.7 | 2.4e-11 | -0.42 | 0.41 | 0.41 | TRUE |
| 3 | GTEx | Colon Transverse | RP11-981P6.1 | 0.14 | 0.05 | enet | 26 | 0.05 | 1.9e-03 | 5.0 | 5.2 | 2.1e-07 | 0.28 | 0.31 | 0.26 | FALSE |