Best TWAS P=2.22e-08 · Best GWAS P=3.55e-17 conditioned to 3.31e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PRDM4 | 0.07 | 0.08 | lasso | 2 | 0.07 | 5.0e-09 | 5.7 | 5.5 | 4.0e-08 | -0.03 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Whole Blood | PRDM4 | 0.10 | 0.08 | lasso | 5 | 0.05 | 1.8e-05 | 5.6 | -5.6 | 2.2e-08 | 0.05 | 0.99 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ASCL4 | 0.03 | 0.03 | blup | 49 | 0.03 | 2.9e-04 | 5.7 | 5.3 | 9.7e-08 | -0.05 | 0.01 | 0.94 | FALSE |