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chr16:24,162,204-25,620,010

Best TWAS P=3.74e-11 · Best GWAS P=8.98e-12 conditioned to 0.0178

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	METSIM	Adipose	SLC5A11	0.23	0.28	lasso	10	0.28	1.6e-42	-5.9	-5.9	2.8e-09	0.72	0.55	0.46	FALSE
2	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SLC5A11	0.17	0.21	lasso	4	0.21	1.7e-17	-5.4	-5.8	7.5e-09	0.70	0.20	0.80	FALSE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC5A11	0.12	0.17	enet	9	0.18	1.1e-35	-5.9	-5.7	1.3e-08	0.73	0.15	0.85	FALSE
4	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SLC5A11	0.27	0.24	lasso	6	0.24	4.5e-12	-6.0	-6.3	3.2e-10	0.80	0.07	0.93	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	SLC5A11	0.27	0.21	lasso	2	0.20	5.2e-12	-6.0	-6.0	2.6e-09	0.71	0.15	0.85	FALSE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC5A11	0.13	0.15	enet	8	0.15	6.6e-17	-6.0	-5.8	5.9e-09	0.69	0.14	0.86	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC5A11	0.07	0.07	enet	7	0.06	1.7e-07	-6.0	-5.9	3.8e-09	0.64	0.13	0.87	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC5A11	0.14	0.20	enet	9	0.20	2.2e-23	-5.9	-6.0	1.7e-09	0.72	0.14	0.86	FALSE
9	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC5A11	0.06	0.05	lasso	1	0.05	4.9e-06	-5.9	-5.9	3.2e-09	0.71	0.05	0.95	FALSE
10	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC5A11	0.14	0.02	blup	62	0.07	1.4e-05	-5.9	-6.2	5.4e-10	0.70	0.01	0.97	FALSE
11	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SLC5A11	0.30	0.33	lasso	2	0.32	2.8e-14	-6.0	-6.6	3.7e-11	0.83	0.03	0.97	TRUE
12	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SLC5A11	0.54	0.32	lasso	6	0.30	1.8e-12	-5.4	-5.7	1.4e-08	0.72	0.16	0.84	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC5A11	0.26	0.28	lasso	6	0.31	1.0e-32	-5.9	-5.7	9.2e-09	0.67	0.15	0.85	FALSE
14	The Cancer Genome Atlas	Soft Tissue Sarcoma	SLC5A11	0.17	0.21	lasso	3	0.18	4.9e-11	-6.0	-6.0	1.9e-09	0.70	0.14	0.86	FALSE
15	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SLC5A11	0.20	0.05	lasso	4	0.04	2.8e-02	-5.9	-5.7	1.5e-08	0.64	0.03	0.22	FALSE
16	The Cancer Genome Atlas	Stomach Adenocarcinoma	SLC5A11	0.12	0.08	enet	7	0.07	7.0e-06	-5.9	-6.0	2.6e-09	0.74	0.10	0.87	FALSE
17	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC5A11	0.21	0.10	lasso	5	0.07	2.2e-03	-5.9	-6.0	2.1e-09	0.72	0.06	0.78	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	SLC5A11	0.35	0.44	lasso	4	0.44	4.2e-47	-5.9	-5.9	4.8e-09	0.71	0.14	0.86	FALSE
19	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SLC5A11	0.24	0.15	lasso	3	0.14	1.1e-04	-5.9	-5.9	3.1e-09	0.72	0.04	0.79	FALSE