Best TWAS P=1.5e-11 · Best GWAS P=9.77e-14 conditioned to 0.000247
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | UBN1 | 0.18 | 0.19 | lasso | 4 | 0.19 | 9.1e-12 | 5.3 | -5.2 | 1.9e-07 | -0.04 | 0 | 1 | TRUE |
| 2 | GTEx | Nerve Tibial | UBN1 | 0.14 | 0.12 | lasso | 4 | 0.11 | 5.6e-08 | 5.2 | -5.2 | 2.4e-07 | -0.04 | 0 | 1 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RP11-462G12.1 | 0.11 | 0.07 | enet | 18 | 0.06 | 1.1e-08 | -7.0 | -6.7 | 1.5e-11 | 0.86 | 0 | 1 | TRUE |