[Hub]/) : Traits : Leg fat percentage (right) :

chr16:73,788,021-75,396,376

Best TWAS P=8.7e-09 · Best GWAS P=6.06e-08 conditioned to 0.68

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RFWD3 0.14 0.03 enet 15 0.04 3.0e-03 3.9 5.5 4.0e-08 -0.73 0.08 0.85 FALSE
2 GTEx Adrenal Gland RFWD3 0.15 0.07 enet 20 0.12 4.6e-05 -5.2 5.3 1.0e-07 -0.76 0.03 0.94 FALSE
3 GTEx Artery Aorta RFWD3 0.15 0.09 lasso 3 0.05 6.2e-04 -5.2 5.1 2.8e-07 -0.78 0.03 0.91 FALSE
4 GTEx Breast Mammary Tissue RFWD3 0.16 0.06 lasso 4 0.08 5.8e-05 4.2 5.3 1.1e-07 -0.77 0.06 0.92 FALSE
5 GTEx Breast Mammary Tissue (Male) GLG1 0.20 -0.01 lasso 5 0.02 8.9e-02 -5.4 5.8 8.7e-09 -0.91 0.02 0.67 TRUE
6 GTEx Cells EBV-transformed lymphocytes RFWD3 0.35 0.25 enet 31 0.27 2.5e-09 -5.2 5.4 8.0e-08 -0.74 0.03 0.97 FALSE
7 GTEx Esophagus Mucosa RFWD3 0.20 0.18 lasso 5 0.23 3.5e-15 4.6 5.7 1.3e-08 -0.82 0.08 0.91 FALSE
8 GTEx Esophagus Muscularis RFWD3 0.18 0.07 lasso 5 0.10 1.4e-06 -5.2 5.3 1.0e-07 -0.77 0.04 0.94 FALSE
9 GTEx Heart Atrial Appendage RFWD3 0.11 0.11 lasso 1 0.07 3.8e-04 -5.2 5.2 2.6e-07 -0.84 0.02 0.96 FALSE
10 GTEx Muscle Skeletal RFWD3 0.08 0.11 lasso 3 0.10 3.1e-10 -5.3 5.3 9.7e-08 -0.85 0.01 0.99 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic RFWD3 0.20 0.14 lasso 5 0.15 9.2e-09 -5.2 5.5 3.7e-08 -0.83 0.01 0.98 FALSE
12 GTEx Stomach RFWD3 0.20 0.08 enet 20 0.13 1.2e-06 4.1 5.5 4.3e-08 -0.71 0.04 0.95 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma RFWD3 0.06 0.07 enet 13 0.08 1.2e-15 -5.2 5.2 1.6e-07 -0.77 0.02 0.98 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma RFWD3 0.12 0.17 enet 6 0.18 3.0e-18 -5.2 5.1 3.0e-07 -0.81 0.01 0.99 FALSE
15 The Cancer Genome Atlas Stomach Adenocarcinoma RFWD3 0.05 0.02 blup 67 0.04 1.2e-03 4.6 5.2 2.5e-07 -0.71 0.06 0.91 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma RFWD3 0.23 0.17 lasso 5 0.23 4.1e-22 4.3 5.3 1.0e-07 -0.76 0.08 0.91 FALSE
17 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RFWD3 0.09 0.06 blup 67 0.04 2.1e-02 4.6 5.3 1.4e-07 -0.67 0.04 0.65 FALSE