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chr16:73,788,021-75,396,376

Best TWAS P=8.7e-09 · Best GWAS P=6.06e-08 conditioned to 0.68

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Breast Mammary Tissue (Male)	GLG1	0.20	-0.01	lasso	5	0.02	8.9e-02	-5.4	5.8	8.7e-09	-0.91	0.02	0.67	TRUE
7	GTEx	Esophagus Mucosa	RFWD3	0.20	0.18	lasso	5	0.23	3.5e-15	4.6	5.7	1.3e-08	-0.82	0.08	0.91	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	RFWD3	0.20	0.14	lasso	5	0.15	9.2e-09	-5.2	5.5	3.7e-08	-0.83	0.01	0.98	FALSE
1	GTEx	Adipose Visceral Omentum	RFWD3	0.14	0.03	enet	15	0.04	3.0e-03	3.9	5.5	4.0e-08	-0.73	0.08	0.85	FALSE
12	GTEx	Stomach	RFWD3	0.20	0.08	enet	20	0.13	1.2e-06	4.1	5.5	4.3e-08	-0.71	0.04	0.95	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	RFWD3	0.35	0.25	enet	31	0.27	2.5e-09	-5.2	5.4	8.0e-08	-0.74	0.03	0.97	FALSE
10	GTEx	Muscle Skeletal	RFWD3	0.08	0.11	lasso	3	0.10	3.1e-10	-5.3	5.3	9.7e-08	-0.85	0.01	0.99	FALSE
2	GTEx	Adrenal Gland	RFWD3	0.15	0.07	enet	20	0.12	4.6e-05	-5.2	5.3	1.0e-07	-0.76	0.03	0.94	FALSE
8	GTEx	Esophagus Muscularis	RFWD3	0.18	0.07	lasso	5	0.10	1.4e-06	-5.2	5.3	1.0e-07	-0.77	0.04	0.94	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	RFWD3	0.23	0.17	lasso	5	0.23	4.1e-22	4.3	5.3	1.0e-07	-0.76	0.08	0.91	FALSE
4	GTEx	Breast Mammary Tissue	RFWD3	0.16	0.06	lasso	4	0.08	5.8e-05	4.2	5.3	1.1e-07	-0.77	0.06	0.92	FALSE
17	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RFWD3	0.09	0.06	blup	67	0.04	2.1e-02	4.6	5.3	1.4e-07	-0.67	0.04	0.65	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	RFWD3	0.06	0.07	enet	13	0.08	1.2e-15	-5.2	5.2	1.6e-07	-0.77	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Stomach Adenocarcinoma	RFWD3	0.05	0.02	blup	67	0.04	1.2e-03	4.6	5.2	2.5e-07	-0.71	0.06	0.91	FALSE
9	GTEx	Heart Atrial Appendage	RFWD3	0.11	0.11	lasso	1	0.07	3.8e-04	-5.2	5.2	2.6e-07	-0.84	0.02	0.96	FALSE
3	GTEx	Artery Aorta	RFWD3	0.15	0.09	lasso	3	0.05	6.2e-04	-5.2	5.1	2.8e-07	-0.78	0.03	0.91	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	RFWD3	0.12	0.17	enet	6	0.18	3.0e-18	-5.2	5.1	3.0e-07	-0.81	0.01	0.99	FALSE