Hub : Genes

GLG1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0530	0.0210	1.4e-03	0.017	0.031	0.008	0.030	0.009	2.9e-03	8.9e-05	3.5e-02	1.2e-04	2.2e-02
2	GTEx	Brain Cerebellum	0.1600	0.0640	5.0e-03	0.010	NA	0.031	NA	0.030	1.5e-01	NA	4.2e-02	NA	4.4e-02
3	GTEx	Breast Mammary Tissue	0.1660	0.0620	2.4e-03	0.082	NA	0.026	NA	0.039	5.1e-05	NA	1.7e-02	NA	4.5e-03
4	GTEx	Breast Mammary Tissue (Male)	0.2045	0.1021	3.4e-02	-0.009	NA	-0.006	NA	0.025	6.0e-01	NA	4.7e-01	NA	8.9e-02
5	GTEx	Breast Mammary Tissue (Female)	0.2280	0.1047	1.3e-02	-0.010	NA	0.121	NA	-0.004	8.4e-01	NA	1.9e-04	NA	4.6e-01
6	GTEx	Esophagus Gastroesophageal Junction	0.1950	0.0650	5.1e-04	0.019	NA	0.109	NA	0.077	6.9e-02	NA	9.4e-05	NA	9.5e-04
7	GTEx	Esophagus Muscularis	0.2520	0.0670	5.1e-06	0.002	NA	0.044	NA	0.029	2.3e-01	NA	1.0e-03	NA	6.8e-03
8	GTEx	Lung	0.0878	0.0330	1.7e-03	0.019	NA	0.050	NA	0.016	1.2e-02	NA	1.0e-04	NA	1.9e-02
9	GTEx	Nerve Tibial	0.2148	0.0638	5.5e-07	0.070	NA	0.029	NA	0.039	1.1e-05	NA	3.7e-03	NA	8.7e-04
10	METSIM	Adipose	0.0809	0.0233	4.4e-07	0.077	0.061	0.071	0.078	0.076	1.4e-11	2.0e-09	7.6e-11	8.2e-12	1.6e-11
11	YFS	Blood	0.1394	0.0233	0.0e+00	0.072	0.082	0.094	0.086	0.091	1.7e-22	1.2e-25	4.7e-29	1.4e-26	2.8e-28

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Bipolar Disorder (2018)	1.1	1.8	4.4	1.1	-0.6	1.5	-2.1	1.4	-1.6	-1.0	-0.5	-1.0	-1.5	-1.6
Bipolar Disorder or Schizophrenia	1.7	4.1	15.9	2.7	-1.5	1.6	-4.0	0.4	-2.8	-0.6	0.7	-2.8	-0.7	-0.1
Depressed Affect (Nagel 2018)	1.5	3.1	10.4	-0.5	-1.4	-1.8	2.5	-2.2	-0.2	-1.4	-3.2	0.6	-0.2	-2.2
Depression (Nagel 2018)	1.8	2.7	9.3	-0.3	-2.3	0.7	1.5	-1.9	-0.1	-2.4	-3.1	-0.9	0.4	-1.3
Intelligence (Savage-Jansen 2018)	0.8	2.6	7.5	2.7	-1.3	0.6	-0.2	-2.2	-1.8	-1.1	-1.4	-2.1	-1.4	-1.0
Neuroticism (Nagel 2018)	1.1	2.6	7.3	-0.0	-0.3	-1.6	1.4	-1.6	-1.2	-2.7	-2.7	-0.8	-0.5	-2.1
Schizophrenia (2018)	1.6	3.4	11.8	2.6	-1.4	0.9	-3.4	-0.5	-2.1	-0.2	1.3	-2.8	0.1	1.3
Schizophrenia vs Biploar Disorder	0.8	1.0	3.0	1.6	-0.7	-1.4	-0.1	-1.5	-0.8	-0.5	0.4	-1.7	0.3	-0.1
Worry (Nagel 2018)	1.6	3.4	10.0	0.4	0.8	-0.2	-0.6	-1.2	-2.0	-3.2	-1.7	-2.6	-2.2	-2.6
Alzheimer’s Disease (in mother)	1.0	1.2	4.3	-0.2	1.4	-1.5	-1.2	-2.1	0.5	0.2	1.1	-1.1	0.3	0.2
Alzheimer’s Disease (in father)	0.6	0.6	2.6	-0.2	-0.1	1.6	0.3	1.0	-0.4	-0.1	-0.7	0.5	0.8	1.3
Alzheimer’s Disease (including proxy)	0.3	0.5	1.4	-0.4	1.1	-0.1	-0.6	-0.8	-0.6	0.1	0.3	-1.2	0.3	0.8
Crohns Disease (2017)	0.3	0.7	1.9	0.9	0.6	-0.7	-1.4	1.1	-1.0	-0.6	0.3	-1.1	0.2	-0.6
Irritable Bowel Disease (IBD)	0.5	1.2	4.8	-0.0	1.4	-0.8	-1.3	2.2	0.1	-0.0	1.5	-1.0	-0.7	-0.3
Ulcerative Colitis (UC)	0.8	1.6	4.4	-1.0	1.8	-0.7	-0.4	2.1	1.3	0.9	2.1	-0.2	-1.1	0.2
Major Depression (MDD)	1.3	1.6	5.8	-0.6	-0.2	-0.5	0.2	-2.2	-0.6	-2.4	-1.5	-0.3	-1.0	-1.7
Reaction Time	0.4	0.7	2.2	0.5	-0.4	1.4	-0.6	1.5	-0.5	-0.3	0.8	-1.4	0.0	0.7
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.6	0.5	-0.9	0.8	0.2	-1.2	-0.6	-0.2	-0.6	-0.6	-0.1	-0.5
Breast Cancer	0.5	1.2	4.2	-0.6	-0.5	-0.9	0.3	0.1	1.6	1.3	0.9	1.0	2.0	1.3
Ovarian Cancer	2.0	2.6	7.3	-0.5	2.7	0.2	0.5	0.3	1.5	2.0	2.4	1.5	1.1	2.4
Prostate Cancer	0.4	0.6	1.6	0.5	-0.1	-0.6	0.3	-0.9	-1.3	-1.3	-0.9	-0.9	0.5	0.4
Age at First Birth	0.6	0.9	2.6	1.0	1.3	-1.3	-1.1	0.3	-0.7	-1.6	0.1	-0.6	-0.8	-0.7
Bipolar Disorder (2011)	1.6	1.5	6.1	1.5	-0.8	0.0	-1.6	-0.2	-1.6	-0.7	-0.1	-2.5	-1.5	0.0
Body Mass Index (BMI) (2010)	0.6	0.8	3.6	-1.9	-0.8	-0.4	0.1	0.9	0.2	-0.4	-0.3	0.4	-0.7	-1.4
Coronary Artery Disease (CAD)	0.7	0.8	2.3	0.5	1.0	-1.0	0.8	-0.2	0.5	1.5	0.4	1.5	-0.9	0.4
Crohns Disease (2012)	0.4	0.7	1.8	0.4	0.1	-0.1	-1.0	1.0	-0.9	0.2	0.5	-1.3	-1.0	-1.1
Mean Putamen Volume	1.2	1.4	3.8	1.4	0.1	-1.4	-0.5	-0.6	1.0	1.9	0.3	2.0	1.3	0.7
Fasting Glucose	0.5	0.6	1.9	-0.6	-1.4	0.2	0.9	1.1	0.1	0.5	-0.4	1.3	-0.4	-0.1
HbA1C	0.5	0.5	2.8	-0.3	0.6	0.9	0.0	-0.3	-0.9	-1.7	-0.7	-0.6	-0.3	-0.1
HDL Cholesterol	0.9	1.5	5.7	0.6	2.4	0.1	2.1	-0.5	-0.3	1.0	-0.2	1.5	0.3	1.6
LDL Cholesterol	0.6	1.0	3.3	-1.8	0.1	0.4	1.6	-0.6	1.5	0.3	-0.0	1.6	-0.4	0.0
Lupus	0.7	1.1	4.6	-1.1	-1.6	-0.7	0.5	0.1	1.1	0.5	-0.9	0.1	2.1	0.8
Neuroticism (2016)	1.2	1.7	4.2	-0.5	-0.5	-1.7	2.0	-0.9	-0.9	-1.6	-2.1	0.0	-0.8	-1.5
Primary Biliary Cirrhosis	0.7	1.0	3.1	1.4	-1.1	0.4	0.0	-1.3	-1.8	-1.0	-0.7	-1.0	-0.3	0.8
Rheumatoid Arthritis	0.4	0.5	2.2	-0.6	1.0	0.9	-0.6	0.5	-0.3	-1.5	-0.1	-0.4	0.4	-0.2
Schizophrenia (2014)	1.7	3.8	12.4	2.9	-1.4	1.2	-3.5	-0.1	-2.3	-0.1	1.2	-3.0	-0.6	1.2
Triglycerides	0.9	1.5	4.7	0.6	-1.1	-1.0	-2.2	-1.6	-0.9	0.0	0.3	-1.6	-1.5	-1.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.7	-1.6	0.4	0.0	0.2	0.1	1.0	1.0	0.4	0.1	0.9	0.7
Ulcerative Colitis	0.4	0.6	5.3	-0.4	-0.2	-0.1	0.1	2.3	0.2	-0.6	0.3	0.3	-0.3	0.3
Blood Eosinophil Count	0.2	1.3	4.3	-0.8	-0.2	0.0	2.1	-1.5	-0.1	-1.0	-1.8	0.6	0.4	-1.5
Blood Platelet Count	0.4	4.4	12.5	-1.1	-2.0	0.1	3.5	-2.0	-0.1	-2.0	-3.5	0.4	-1.2	-2.9
Blood Red Count	0.4	4.2	11.8	-0.5	-2.4	1.6	3.4	1.3	0.6	-0.3	-2.5	3.4	2.0	1.2
Blood White Count	0.3	2.4	11.0	-0.5	1.0	-1.4	-0.5	-1.4	0.8	0.7	2.4	0.2	1.7	3.3
Heel T-Score	0.2	1.9	5.2	1.3	2.3	-1.8	0.2	-0.8	-1.7	-1.4	-1.5	1.2	-0.8	-1.1
BMI	1.2	7.2	20.2	-1.7	-4.0	1.8	4.5	-2.5	-0.2	-0.8	-4.0	1.9	3.2	-0.6
Height	0.1	1.9	7.1	0.3	1.0	-0.6	-2.7	0.4	-0.1	-1.4	-0.5	-1.0	-2.1	-2.1
Waist Hip Ratio (WHR)	0.1	0.5	1.7	-0.9	-0.3	0.1	0.9	-0.2	0.8	0.1	-0.8	1.3	0.5	-0.5
Systolic Blood Pressure	0.2	1.2	3.1	-1.0	-0.7	0.9	1.3	1.5	1.8	-0.0	-0.7	1.7	0.5	-0.7
Smoking Status	0.4	0.9	3.3	-1.8	-0.3	-1.4	0.8	-1.4	-0.2	-0.1	-0.6	1.0	0.6	-0.7
Allergy or Eczema	0.3	0.8	2.9	-0.9	1.2	0.2	-0.1	0.9	1.0	1.0	1.7	-0.4	-0.1	0.8
Cardiovascular Disease	0.5	1.6	6.5	-1.6	0.6	1.8	2.5	0.2	1.6	0.8	0.2	0.6	1.1	0.8
Hypothyroidism (self reported)	0.9	2.1	4.6	-0.8	-1.8	-2.1	-0.8	-1.9	-1.3	-1.4	-1.1	-1.3	-1.2	-1.5
Respiratory disease	0.9	2.0	5.1	-0.7	-1.8	-1.7	1.1	-1.7	-2.0	-0.7	-1.0	-2.3	-0.2	-0.1
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.9	-1.6	-1.4	1.0	1.7	0.4	0.9	-0.3	-1.0	-0.7	1.3	-0.8
Lung FEV1/FVC ratio	0.6	3.2	12.0	3.5	0.7	0.9	0.2	1.9	-1.2	-0.4	-2.4	2.6	1.7	-1.1
Lung FVC	0.8	4.0	14.0	-1.2	1.5	0.0	-0.1	1.3	3.2	3.1	3.7	0.9	-0.1	1.9
Neuroticism	1.6	3.8	11.9	-0.4	-0.3	-1.4	1.6	-1.6	-2.1	-3.3	-3.5	-0.7	-0.7	-2.5
Chronotype (morning person)	0.7	1.6	4.3	-1.3	-1.2	0.6	1.3	0.4	1.7	0.7	-0.5	2.1	1.3	-1.8
Hair Pigment	0.0	0.8	2.8	-0.8	1.7	0.3	-0.9	-0.1	0.6	0.5	1.6	-0.2	-0.7	-0.5
Tanning	0.0	0.6	1.6	-0.6	0.5	0.9	-0.7	0.2	1.3	0.8	1.2	0.0	-0.6	0.5
Hand grip strength (left)	0.7	1.8	4.6	0.7	-1.9	-2.1	-0.6	-0.8	-1.0	-0.4	-0.4	-1.2	-2.1	-1.9
Number of treatments/medications taken	0.4	0.7	1.9	-1.4	-0.5	0.1	0.9	-0.5	-0.2	-0.0	-0.9	-0.9	-1.3	-1.2
Average weekly spirits intake	1.0	1.2	4.4	-1.0	1.3	-0.2	0.7	-0.1	1.9	1.2	2.1	-0.0	0.5	0.5
Sensitivity / hurt feelings	0.3	0.5	1.5	-0.3	0.9	-1.2	-0.1	0.1	1.2	0.7	0.1	0.7	0.9	0.5
Frequency of depressed mood in last 2 weeks	1.1	1.5	5.6	0.2	-0.4	-0.6	1.5	-1.3	0.2	-2.3	-2.4	-0.2	0.1	-1.0
Hearing difficulty/problems: Yes	0.6	0.9	3.5	1.0	0.2	0.3	-0.0	-1.9	-1.3	-1.2	-1.3	-0.7	0.5	-0.2
Relative age of first facial hair	0.2	0.5	1.6	0.8	-1.0	-0.3	-1.3	-0.5	-1.1	-0.3	0.4	0.2	0.1	0.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.3	-0.4	-0.4	1.1	-0.1	-0.6	-0.6	-0.0	0.7	-1.5	-1.0	0.1
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.1	-1.7	2.0	0.6	0.7	0.4	1.4	0.4	0.4	1.1	0.7	1.0
Ever had hysterectomy (womb removed)	0.7	0.8	2.2	-1.2	-0.4	0.6	1.5	0.9	0.8	0.6	-0.9	1.4	-0.1	0.0
Systolic blood pressure, automated reading	0.5	1.4	5.7	-1.3	0.1	1.0	1.7	0.3	2.4	0.4	-0.4	1.7	0.9	-0.2
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.5	-2.1	0.6	-0.4	0.7	-0.4	1.0	-0.3	1.1	-1.6	-0.6	-0.6
Angina	1.0	1.3	3.1	-1.7	1.7	1.1	1.6	0.1	0.6	1.6	0.2	1.1	0.2	0.1
Medication for hormone replacement therapy	0.9	1.0	3.5	-1.0	-0.0	-1.2	-1.9	0.0	0.8	0.4	1.4	-0.3	0.5	1.3
Vitamin and mineral supplements	0.7	0.9	1.7	-0.5	-1.3	-0.9	1.3	-1.1	-0.2	-1.3	-1.3	0.7	0.7	-0.5
Supplements: Zinc	0.9	1.0	5.6	1.1	-0.3	-1.1	-0.7	2.4	-0.5	0.4	-0.1	-0.3	1.0	0.9
Medication: Co-codamol	0.9	1.0	2.9	-0.8	-1.5	0.7	1.7	-1.2	0.8	0.3	-0.8	-0.7	1.3	0.5
Medication: Metformin	1.0	1.4	7.8	-0.8	-1.0	0.3	2.8	-1.2	0.4	-0.3	-1.8	0.1	0.0	-1.1
Diabetes (father)	0.5	0.6	1.6	0.5	0.7	0.0	-0.8	0.2	0.8	1.3	1.3	0.6	-1.1	0.3
Diabetes (mother)	1.4	1.8	4.9	-1.3	-1.3	-1.3	0.8	0.8	-0.3	-1.6	-1.9	1.0	-1.1	-2.2
Severe depression (siblings)	1.2	1.3	3.3	0.2	1.0	-0.3	-1.0	-0.2	1.6	1.2	1.5	0.2	1.8	1.6
Pack years adult smoking proportion	0.9	1.4	3.9	-0.7	-0.2	-0.6	0.4	1.2	-1.4	-2.0	-1.2	-0.4	-1.6	-1.8
Impedance of leg (right)	0.2	1.0	4.2	0.3	1.2	-1.4	0.8	1.5	0.5	-0.2	0.0	2.0	-0.1	0.2
Leg fat-free mass (left)	0.2	1.3	3.9	-1.0	-1.7	1.1	0.9	-0.9	0.0	-0.9	-2.0	0.4	1.3	-0.9
Trunk fat percentage	1.8	7.3	26.3	-2.9	0.3	1.9	5.1	0.9	2.9	0.8	-2.2	4.5	2.7	0.0
Hand grip strength (right)	0.9	2.4	5.8	1.3	-1.7	-1.7	-1.5	-1.0	-1.2	-0.8	-0.7	-1.7	-2.4	-2.1
Townsend deprivation index at recruitment	0.8	1.2	3.8	1.1	-0.2	-0.8	-0.4	-1.9	-1.3	-1.4	-0.6	-1.6	0.0	0.5
Current tobacco smoking	0.2	0.3	0.9	-0.7	-0.8	0.2	0.3	-0.3	-0.5	-0.9	-0.9	0.0	0.4	0.3
Average weekly fortified wine intake	1.4	1.6	4.2	0.0	0.9	1.2	-1.2	0.8	-0.7	0.8	2.0	-1.8	0.8	2.1
Maternal smoking around birth	0.3	0.5	1.1	0.2	0.4	-0.9	0.9	-1.0	-0.0	-0.1	-1.1	1.0	-0.0	-0.4
Fed-up feelings	1.9	3.5	12.6	-0.9	-0.9	-0.9	3.1	-1.4	-0.2	-1.4	-3.5	1.7	-0.5	-2.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	6.2	0.3	-1.1	1.2	1.4	-0.9	-0.6	-1.8	-2.5	0.4	-0.3	-0.8
Relative age voice broke	0.3	0.5	2.7	0.4	0.6	-0.6	-1.6	0.7	0.3	-0.4	0.7	0.1	0.3	0.6
Taking other prescription medications	0.5	0.7	2.1	-1.4	-1.2	0.0	1.4	-0.6	-0.6	0.4	-0.8	-0.5	0.0	0.9
Age when periods started (menarche)	0.8	1.9	5.6	-0.2	-0.6	-1.9	0.4	-1.6	-0.9	-1.5	-2.0	0.5	-0.9	-2.4
Bilateral oophorectomy (both ovaries removed)	2.4	2.8	7.3	-2.6	1.8	-0.2	1.0	0.2	2.5	1.8	0.7	2.7	1.4	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	5.6	0.1	-0.6	0.3	0.5	-0.4	-2.0	-1.7	-2.4	1.2	0.9	-1.0
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	4.0	-0.6	0.6	-1.9	-1.0	-1.5	-0.4	0.4	2.0	-1.8	-0.2	0.2
Qualifications: CSEs or equivalent	1.9	2.5	10.9	1.4	-3.3	1.3	-1.4	1.1	-2.5	0.9	-1.0	0.7	0.1	1.3
Serious illness, injury or assault to yourself	0.8	0.9	2.4	1.0	-0.9	-1.3	0.7	-0.6	-1.5	-0.7	-0.5	-1.3	0.7	0.7
High blood pressure	0.7	2.1	7.0	-2.4	0.9	1.7	2.6	1.0	1.8	0.2	0.2	1.3	0.6	0.4
Hayfever, allergic rhinitis or eczema	0.9	2.0	3.9	-1.3	1.0	0.7	0.6	1.7	1.8	1.8	1.7	0.4	1.4	2.0
Multivitamins +/- minerals	1.1	1.3	4.2	0.1	1.2	-0.5	-2.0	1.3	-0.8	1.0	1.5	-1.5	-1.0	0.3
Stomach or abdominal pain in last month	0.8	1.0	3.1	-0.3	1.0	0.4	1.1	0.8	1.8	0.6	0.6	0.3	1.6	0.9
Supplements: Glucosamine	0.6	0.8	1.9	0.5	1.0	0.5	-1.1	0.0	-0.5	-0.2	1.3	-1.4	-1.0	0.9
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	3.0	1.7	-0.7	0.3	1.4	-0.7	0.4	1.1	-0.4	0.8	1.3	1.1
Medication: Atenolol	1.0	1.3	4.3	-2.1	0.2	1.0	1.1	1.7	0.9	0.4	-0.7	1.2	1.2	0.1
Medication: Levothyroxine sodium	0.9	1.6	5.9	-0.9	-2.4	-0.9	-0.1	-0.5	-1.5	-0.9	-1.7	-1.1	-1.1	-1.3
Sitting height	0.2	1.5	3.7	0.9	0.5	-1.7	-1.7	0.8	0.8	1.8	1.9	-1.1	0.2	0.8
Chronic bronchitis/emphysema (father)	0.5	0.6	1.8	-0.3	1.2	-0.5	0.8	0.2	0.2	-1.3	0.2	-0.0	0.9	1.2
High blood pressure (mother)	0.5	0.8	1.8	0.4	-1.3	0.3	0.3	-1.1	-0.9	-1.3	-1.0	-0.1	-0.7	-1.0
Body mass index (BMI)	1.3	5.5	20.8	-2.6	-1.4	2.3	4.6	-0.8	1.5	0.2	-2.6	3.0	2.8	0.1
Impedance of leg (left)	0.3	1.3	3.7	0.2	1.4	-1.7	1.0	1.9	0.6	0.0	0.3	1.9	-0.8	-0.0
Leg predicted mass (left)	0.2	1.3	3.8	-1.0	-1.8	1.1	1.0	-0.8	0.1	-0.8	-2.0	0.4	1.4	-0.9
Trunk fat mass	1.3	5.7	19.9	-2.8	-0.3	1.7	4.5	0.3	2.3	0.1	-2.5	3.8	2.5	-0.5
Waist circumference	1.1	4.1	12.7	-1.9	-1.1	1.4	3.6	-1.1	1.4	-0.3	-2.4	3.0	2.8	-0.0
Number of incorrect matches in round	0.5	0.8	2.7	0.7	1.3	-0.8	-1.3	-0.6	-1.6	-0.7	0.4	-0.8	-0.2	0.1
Past tobacco smoking	0.5	0.9	4.4	0.5	0.9	2.1	-0.3	1.7	0.8	0.4	0.2	-0.4	-0.3	0.1
Alcohol usually taken with meals	1.0	1.7	8.4	0.2	0.6	-0.2	-1.2	1.2	-0.1	0.4	1.7	-1.7	-2.9	-0.6
Nervous feelings	0.7	1.4	5.8	0.3	1.1	1.0	-0.2	0.2	-1.6	-2.4	-1.2	-0.8	-1.1	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.1	1.4	-1.2	-0.7	0.1	-1.1	-1.3	-1.8	-1.5	-1.7	-0.3	-0.4
Hearing difficulty/problems with background noise	1.0	1.6	5.9	-0.4	0.3	0.4	1.5	-1.9	0.2	0.5	-0.8	0.1	-2.0	-2.4
Hair/balding pattern: Pattern 2	0.6	0.8	3.2	0.4	1.8	-0.5	0.8	0.5	0.0	0.7	1.4	0.8	-1.1	0.1
Had menopause	1.2	1.5	7.3	-1.5	2.7	0.4	1.0	-0.6	0.6	0.7	1.1	0.2	-0.1	1.8
Had other major operations	0.4	0.4	1.9	0.1	-0.4	-0.1	1.4	-0.4	0.3	0.8	-0.7	0.0	0.1	1.2
Forced vital capacity (FVC)	0.4	1.4	7.8	1.0	-0.3	-0.3	-2.8	0.4	0.2	-0.3	1.6	-0.7	-1.5	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	9.0	0.1	-0.8	0.2	0.5	-0.0	-1.9	-2.0	-3.0	1.2	0.3	-1.9
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	9.7	-0.3	-0.9	3.1	1.5	-0.2	0.9	-0.3	-1.1	0.7	0.1	-1.1
Qualifications: None of the above	0.5	1.1	4.8	-0.1	2.2	-0.1	0.1	1.4	0.8	0.3	1.4	-0.7	0.5	1.3
Financial difficulties in last 2 years	1.4	1.9	5.3	1.3	-1.2	-2.1	-0.1	-1.6	-0.8	-0.0	-0.1	-0.5	2.3	2.1
Mouth/teeth dental problems	0.7	1.1	3.6	1.7	-0.4	0.5	-1.9	1.6	-0.4	1.2	0.6	-0.4	-0.2	-0.7
Heart attack	1.4	1.8	6.5	-2.2	2.5	0.9	0.4	-0.1	1.6	0.9	1.2	1.4	0.7	0.2
Allergy	0.2	0.5	1.3	0.9	-0.2	-0.5	-0.6	-0.2	-0.5	-0.9	-0.9	0.4	-0.3	-1.1
Pain all over the body in last month	0.6	0.6	1.9	0.4	-1.4	-0.4	-0.3	-0.8	-1.2	0.2	0.6	-0.7	0.5	1.2
Diabetes (self-reported)	1.2	1.9	8.7	-3.0	0.2	0.7	2.5	-0.3	2.1	0.0	0.2	-0.0	0.1	-0.6
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	4.6	-1.2	-0.1	0.6	0.2	1.2	1.4	1.1	1.6	0.6	1.0	2.1
Medication: Ramipril	0.4	0.5	2.2	-0.7	0.1	-1.5	0.9	-0.8	-0.0	-0.3	-0.4	0.3	-0.3	-0.9
Medication: Simvastatin	1.7	2.4	5.9	-0.5	2.4	2.0	1.1	0.4	1.6	1.8	0.2	2.4	1.5	1.2
Fluid intelligence score	0.7	1.5	3.3	0.2	-0.8	1.6	-1.4	-1.8	-0.9	-0.4	-0.2	-1.8	-1.2	-1.4
Illnesses of siblings	0.8	1.1	4.1	0.3	-1.1	1.0	-1.0	0.3	0.4	0.7	0.9	-0.5	2.0	1.7
Neuroticism score	0.9	1.9	7.9	-0.0	0.8	-0.5	1.5	-0.9	-1.2	-2.0	-2.8	0.6	-0.4	-1.9
Weight	0.7	3.6	11.0	-2.2	-1.2	1.5	3.3	-0.6	1.2	-0.5	-2.7	2.3	2.0	-0.9
Impedance of arm (right)	0.4	1.9	11.6	1.7	1.6	-0.2	-1.4	3.4	0.4	0.3	0.9	-0.3	0.2	0.7
Arm fat percentage (right)	1.3	5.2	18.6	-2.0	-0.4	1.9	4.3	0.4	1.8	0.1	-2.5	3.2	3.3	0.3
Trunk fat-free mass	0.2	1.1	2.5	-1.3	-1.1	-0.3	0.2	-1.3	-0.1	-1.3	-1.6	0.3	0.7	-1.5
Hip circumference	0.7	2.9	8.2	-1.2	-1.3	1.4	2.8	-0.6	0.8	-0.4	-2.1	2.2	2.9	-0.0
Time employed in main current job	0.5	0.6	1.9	-0.3	-0.6	1.0	0.7	0.7	0.2	-1.4	-1.2	-0.3	0.7	-0.4
Alcohol intake versus 10 years previously	0.8	1.2	3.6	1.2	-1.9	0.9	-0.7	0.4	-1.2	0.1	-1.2	-1.9	-0.4	0.2
Father’s age at death	0.9	1.1	3.4	1.0	0.2	0.1	-1.1	-1.1	-1.2	-1.3	0.0	-1.8	-1.7	-0.2
Worrier / anxious feelings	0.6	1.1	2.8	0.5	0.8	0.9	-0.7	0.3	-1.0	-1.4	-0.6	-1.4	-1.2	-1.7
Frequency of tiredness / lethargy in last 2 weeks	3.4	5.6	12.4	1.5	-3.0	-0.0	-0.4	-3.2	-3.5	-3.1	-3.3	-2.2	-0.7	-0.9
Falls in the last year	0.6	0.8	2.9	-0.5	-1.2	0.2	0.8	-0.3	-0.7	0.2	-0.3	1.3	0.9	1.7
Hair/balding pattern: Pattern 3	0.7	1.0	3.3	-1.4	-1.8	0.1	-0.3	0.6	1.0	-0.3	-1.4	-0.5	1.4	0.1
Number of live births	0.4	0.6	2.9	0.3	-1.7	0.0	-0.3	-1.2	-0.8	0.4	-0.6	0.0	-0.9	-0.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	7.8	1.6	-0.5	0.2	-2.8	0.5	0.1	-0.1	1.1	0.1	-0.8	-0.7
Pulse rate	0.6	1.1	3.7	-0.9	-0.6	1.3	0.8	-0.0	1.6	-0.5	-0.5	1.9	1.2	0.5
Happiness	0.4	0.5	2.6	-0.1	1.6	0.4	0.3	-0.0	0.3	-0.6	-0.1	0.9	-0.4	-1.0
Noisy workplace	1.3	1.6	5.4	-1.4	0.2	-0.0	1.8	-0.9	1.1	0.7	-0.1	2.3	1.6	1.4
Qualifications: A levels/AS levels or equivalent	1.6	3.6	8.7	1.1	-1.6	-0.2	-2.2	-0.7	-2.7	-3.0	-1.2	-2.4	-1.7	-2.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.3	0.1	-1.4	-1.5	0.2	-1.1	0.4	1.5	0.2	0.8	-0.1	0.2
Mouth/teeth dental problems: Dentures	0.5	0.9	4.2	-1.5	0.2	1.1	2.1	0.8	0.5	-0.5	-0.2	0.0	-0.2	1.0
Asthma	0.6	1.2	3.2	-0.4	-1.7	-0.5	0.8	-1.1	-1.8	-0.5	-1.3	-1.4	-0.8	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	7.5	1.3	-2.7	0.1	-0.1	1.0	-1.2	-0.7	-1.3	0.1	0.3	-0.2
Medication: Cholesterol lowering	0.7	1.1	3.6	-1.9	0.4	1.3	1.1	-0.4	1.8	0.9	0.1	-0.0	0.7	-0.5
Depression (self-reported)	0.5	0.6	2.5	0.1	-1.1	0.3	0.8	0.4	-1.0	-1.0	-1.6	-0.2	-0.4	-0.6
Medication: Lansoprazole	0.3	0.4	1.4	-0.3	-0.2	-0.1	0.1	0.3	0.4	-0.5	-0.1	-0.7	-1.2	-1.2
Prospective memory result	0.5	0.7	1.3	-0.1	-1.0	-0.9	1.0	0.8	-0.5	-1.1	-0.6	-0.6	1.0	0.9
Lung cancer (father)	0.4	0.5	1.2	-1.1	1.1	-0.5	0.9	-0.5	0.3	-0.9	-0.7	0.3	0.3	-0.6
Illnesses of mother	0.9	1.1	6.0	0.4	0.7	0.4	-0.4	2.4	-0.2	1.4	1.2	0.2	0.0	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	5.8	1.6	-1.4	0.6	-2.4	0.5	-0.5	-0.1	1.0	-0.3	-0.5	0.0
Pulse wave Arterial Stiffness index	1.4	1.6	3.8	-0.9	1.8	-1.1	-0.8	-1.5	1.8	1.2	1.9	-0.7	-0.4	-0.0
Impedance of arm (left)	0.4	2.1	11.7	1.8	1.6	-0.2	-1.5	3.4	0.4	0.5	1.2	-0.5	-0.6	0.5
Arm fat mass (right)	1.3	5.3	18.9	-2.3	-0.9	1.7	4.3	-0.2	1.6	-0.3	-2.9	3.2	3.0	-0.3
Trunk predicted mass	0.2	1.2	2.9	-1.3	-1.2	-0.4	0.2	-1.3	-0.1	-1.4	-1.7	0.3	0.7	-1.6
Standing height	0.2	1.8	5.7	0.3	0.1	-1.9	-2.1	0.3	-0.3	-1.6	-0.7	-1.1	-1.4	-2.4
Length of working week for main job	1.5	1.7	9.0	-1.1	1.1	-3.0	1.2	-0.7	0.2	-0.4	-0.6	1.6	-1.0	-1.3
Exposure to tobacco smoke at home	1.0	1.1	4.5	2.1	-0.4	-1.1	-0.8	-0.4	-1.1	0.1	-0.1	-1.4	-1.4	-0.8
Breastfed as a baby	1.3	1.6	4.9	1.2	0.3	-0.8	-2.2	-0.3	-1.5	0.2	2.0	-1.5	-0.3	1.3
Tense / ‘highly strung’	1.1	1.8	7.8	0.2	0.3	-0.6	0.4	-1.3	-1.4	-2.8	-1.9	-0.8	-1.1	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	3.4	-1.1	0.2	0.7	1.3	-1.4	1.1	-0.4	-1.2	1.8	1.4	-0.4
Hair/balding pattern: Pattern 4	0.4	0.9	2.9	0.6	0.5	-0.1	-0.9	-0.3	0.3	1.1	1.7	-1.7	-0.9	-0.3
Birth weight of first child	0.4	0.8	2.2	-1.2	0.0	-1.0	-1.5	-0.9	0.0	-0.5	0.6	-1.1	-0.4	-0.9
Peak expiratory flow (PEF)	0.8	1.9	8.1	2.8	-1.7	0.2	-2.4	0.4	-1.4	-0.0	0.1	-0.9	-0.9	-0.3
Pulse wave reflection index	1.0	1.3	4.2	-0.1	-0.1	-1.5	-0.5	-2.0	0.3	1.4	0.7	-1.4	-1.4	-0.8
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.8	-0.0	-0.9	1.4	0.3	-0.7	0.1	-0.6	-0.6	-0.4	1.0	-0.2
Loud music exposure frequency	1.0	1.1	5.2	1.5	-1.2	-0.5	0.2	-2.3	-0.7	-0.4	-1.2	-0.5	0.5	-0.8
Qualifications: O levels/GCSEs or equivalent	2.8	4.4	12.7	1.8	-2.0	-1.7	-1.6	-1.3	-3.6	-2.6	-1.8	-2.3	-1.7	-1.8
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	9.8	-0.2	0.6	-1.6	-1.5	-3.1	0.4	-1.8	-0.0	0.1	-0.2	-0.4
Blood clot in the leg (DVT)	0.3	0.4	1.7	0.8	0.0	0.2	-0.6	0.0	0.1	-0.8	-0.1	-0.6	-0.9	-1.3
Medication: Paracetamol	0.6	0.9	2.5	-0.7	-1.6	-0.2	0.8	0.5	-0.3	-0.4	-1.3	-0.2	-1.5	-1.4
Headache pain in last month	1.0	1.8	4.8	0.8	-0.5	-2.2	-1.2	-0.8	-1.0	-0.4	0.1	-1.5	-2.2	-1.9
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.2	1.1	0.2	-1.1	-1.1	0.0	-1.1	-0.1	0.5	0.3	-0.6	0.5
Glaucoma (self-reported)	0.9	1.1	3.0	-0.7	0.2	-0.6	0.8	-0.9	1.2	0.9	0.0	1.5	1.7	1.4
Gout (self-reported)	0.7	0.9	5.1	-1.6	0.8	2.3	0.8	0.3	0.4	0.2	0.2	0.6	0.6	0.1
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	5.5	-2.0	-2.3	-1.6	0.2	-1.6	-1.1	-1.4	-2.0	-0.6	-0.8	-1.8
Medication: Amlodipine	0.7	0.9	2.5	-1.3	0.7	0.9	1.5	0.2	0.8	0.4	0.3	0.0	1.3	1.6
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.6	-0.6	0.7	-0.8	0.6	0.7	-0.4	0.7	-0.4	-0.4	-0.3	-0.1
Birth weight	0.8	1.8	4.8	-0.8	2.0	-1.2	-2.1	-0.8	0.3	0.1	1.8	-2.2	-0.8	0.1
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.7	-0.8	0.3	-0.5	0.3	-0.1	-0.2	0.2	-0.8	0.8	-0.7	-0.9
High blood pressure (siblings)	1.6	2.3	5.9	-0.1	-1.4	-1.3	2.2	-1.7	-1.5	-0.6	-2.4	0.2	-1.9	-1.6
Forced vital capacity (FVC), Best measure	0.3	1.0	5.2	0.8	-0.8	-0.3	-2.3	0.4	0.1	-0.3	1.8	-0.7	-0.7	0.5
Body fat percentage	1.8	7.2	28.1	-3.0	0.0	1.8	5.3	0.3	2.7	0.7	-2.2	4.3	2.9	0.3
Leg fat percentage (right)	2.3	8.4	33.1	-3.2	-0.2	1.8	5.8	-0.2	2.7	0.5	-2.4	4.5	3.3	0.6
Arm fat-free mass (right)	0.3	1.5	3.2	-1.8	-1.2	0.1	1.7	-1.5	0.3	-0.7	-1.6	1.1	0.5	-1.2
Exposure to tobacco smoke outside home	0.2	0.3	0.9	0.1	0.9	0.3	0.6	0.3	0.4	0.2	-0.7	0.8	0.7	0.6
Comparative body size at age 10	1.2	3.4	8.0	0.9	-2.4	-0.7	1.1	-0.5	-1.6	-1.4	-2.4	-2.8	-1.8	-2.7
Number of full brothers	0.9	1.1	6.1	1.1	-0.5	-1.8	-0.4	-2.5	-0.5	-0.9	0.0	0.4	0.2	0.3
Worry too long after embarrassment	0.2	0.3	1.0	0.4	-0.4	1.0	1.0	0.2	-0.4	0.0	-0.7	-0.4	-0.3	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.8	-0.8	-0.9	0.0	0.7	-1.7	0.4	-1.3	-1.1	-1.1	0.7	-0.1
Wheeze or whistling in the chest in last year	1.5	2.6	5.3	0.0	-1.8	-1.2	2.3	-2.0	-2.0	-1.9	-2.3	-1.2	-0.5	-0.6
Number of children fathered	0.7	0.7	2.0	-0.3	1.2	-1.1	-0.1	-1.1	1.1	0.2	0.4	1.4	0.6	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	5.9	-0.3	2.3	0.7	-1.5	1.1	1.0	1.9	2.4	-1.0	0.1	0.3
Age at first live birth	0.7	1.2	6.2	1.0	0.2	-0.1	-2.5	-0.3	-0.0	0.6	1.8	-1.4	-0.8	0.5
Pulse wave peak to peak time	1.3	1.6	3.8	0.8	-1.6	1.0	0.7	1.7	-1.8	-1.5	-1.9	0.6	0.2	-0.3
Health satisfaction	0.2	0.3	1.4	-0.3	0.3	-0.6	0.0	-1.2	-0.8	-0.6	-0.1	-0.0	-0.6	-0.5
Shortness of breath walking on level ground	0.5	0.6	2.9	1.4	-0.2	-0.2	0.4	-1.7	-0.6	0.1	-0.8	0.1	-0.5	-0.8
Qualifications: College or University degree	0.8	2.4	8.3	1.0	-0.5	-0.4	-2.9	-0.9	-1.1	-1.5	0.9	-2.8	-1.3	-1.4
Eye problems/disorders: None of the above	0.8	0.9	3.0	1.7	-1.4	0.5	0.2	-0.9	-0.2	-0.2	-0.1	-0.8	1.7	0.9
Mouth/teeth dental problems: Loose teeth	0.8	0.9	3.1	0.2	-0.7	-1.8	-0.7	-1.6	-1.2	-0.1	-0.6	0.5	-1.2	-0.0
Emphysema/chronic bronchitis	1.2	1.3	5.0	0.8	-1.6	0.5	-0.1	-2.2	-1.8	-0.1	-0.4	-1.6	-0.5	0.3
Medication for pain relief, constipation, heartburn	1.2	2.1	6.9	1.8	2.6	0.5	-1.7	0.9	0.8	0.1	2.1	0.3	1.5	1.4
Neck or shoulder pain in last month	0.5	0.7	3.3	-1.8	0.5	-0.6	1.6	0.2	0.4	-0.5	-0.5	0.3	-0.1	-0.1
Medication: Blood pressure	0.3	0.5	1.3	-1.1	0.4	0.7	1.0	0.6	0.5	-0.2	-0.7	0.1	0.1	-0.9
Angina (self-reported)	1.2	1.5	4.2	-2.0	1.7	1.2	2.0	0.2	0.8	1.6	0.0	1.1	0.0	-0.1
Migraine (self-reported)	0.5	0.6	2.5	0.8	-1.1	-1.1	0.2	-1.6	0.2	-0.3	-1.0	-0.5	-0.0	-0.3
Medication: Ibuprofen	0.7	0.8	5.6	0.7	-2.4	-0.2	-0.0	1.2	-0.4	0.1	-0.7	0.7	0.3	-0.4
Medication: Allopurinol	0.4	0.5	1.9	-1.0	0.7	1.4	0.3	0.7	-0.4	-0.8	-0.6	-0.2	0.7	-0.4
Medication: Omeprazole	0.5	0.6	1.9	-0.2	0.6	-0.9	-0.1	-1.4	0.0	0.2	0.4	-0.9	1.1	1.3
Medication: Seretide 50 evohaler	1.0	1.2	5.2	-0.7	1.1	-1.0	0.7	-1.3	0.3	0.3	-0.0	1.1	2.3	1.3
Mean time to correctly identify matches	0.5	0.9	3.5	-0.9	1.1	0.7	-0.4	0.9	1.0	0.2	1.9	-1.1	-0.3	0.9
Heart disease (mother)	0.3	0.4	1.3	-1.0	0.5	0.0	0.4	0.4	1.1	-0.2	0.7	-0.5	0.2	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.8	1.3	-0.7	0.3	-0.6	1.4	-0.0	1.3	0.9	-0.5	0.2	1.3
Whole body fat mass	1.4	5.8	21.7	-2.7	-0.6	1.7	4.7	-0.2	2.0	0.1	-2.7	3.5	2.7	-0.2
Leg fat mass (right)	1.8	7.0	26.6	-2.9	-1.0	1.9	5.2	-0.4	2.1	0.2	-2.8	3.9	3.0	0.1
Arm predicted mass (right)	0.3	1.6	3.6	-1.9	-1.4	0.2	1.7	-1.5	0.3	-1.0	-1.7	1.0	0.4	-1.4
Pulse rate, automated reading	0.4	1.2	8.0	-1.1	0.7	0.4	0.5	0.3	2.8	-0.1	0.4	1.4	0.8	0.2
Alcohol intake frequency.	0.5	1.3	4.5	0.9	-1.0	1.3	-0.3	-2.1	-1.2	-0.6	-1.3	0.1	1.4	0.6
Comparative height size at age 10	0.3	1.8	5.4	0.7	1.3	0.1	-2.1	1.8	-0.7	-0.4	1.3	-2.3	-1.4	-0.8
Number of full sisters	1.5	1.8	7.5	0.6	-2.7	0.4	-1.2	0.2	-2.1	-1.7	-1.5	-0.7	0.3	-0.5
Suffer from ‘nerves’	1.7	2.6	7.7	0.8	0.6	-1.2	0.1	-0.6	-1.6	-2.4	-1.6	-1.6	-2.1	-2.8
Overall health rating	0.2	0.5	2.8	-1.7	-0.2	0.7	0.6	-0.6	0.3	0.3	-0.5	-0.3	-0.7	-1.0
Chest pain or discomfort	1.4	2.0	7.3	0.9	-1.0	-0.6	-2.2	-2.0	-1.5	-1.0	0.2	-2.7	0.9	0.2
Had major operations	2.5	2.9	7.6	0.6	-1.0	-1.9	0.4	-0.9	-1.2	-2.5	-1.7	-1.6	-2.4	-2.8
Age at last live birth	1.3	1.9	8.1	1.3	-0.5	0.6	-2.8	-1.5	-1.2	-1.4	0.0	-1.8	-1.2	-0.2
Family relationship satisfaction	0.8	1.0	3.4	-1.2	-0.7	0.3	1.7	0.9	0.4	0.3	-0.3	1.8	1.0	0.8
Leg pain on walking	0.4	0.5	1.4	-0.1	-0.2	0.6	1.1	-1.2	-0.5	-0.5	-0.8	-0.1	-0.9	-0.6
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	9.8	-1.5	-0.2	0.1	1.3	-0.0	1.2	1.1	0.2	3.1	1.4	0.5
Commuting to job workplace: Car/motor vehicle	1.6	1.8	4.5	0.1	0.9	1.1	0.2	2.0	1.0	1.8	1.9	0.8	1.2	2.1
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	7.7	-1.5	1.0	2.8	-0.6	1.4	1.7	0.1	0.7	-0.1	-1.0	-1.6
Medication: Aspirin	0.9	1.2	3.1	-1.8	-0.5	1.2	1.7	0.0	0.5	1.6	-0.5	-0.3	-1.5	-0.5
Supplements: Vitamin C	0.7	0.8	2.1	1.2	0.7	0.3	-0.8	0.3	-0.6	-1.3	-0.2	-1.0	0.8	1.4
Knee pain experienced in last month	0.3	0.4	1.1	-1.0	0.9	-0.7	0.1	-1.0	-0.1	-0.9	0.4	-0.2	0.3	0.5
Hypertension (Self-reported)	1.0	2.7	8.6	-2.9	1.1	1.7	2.8	1.2	2.1	0.5	0.5	1.4	0.7	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.4	0.7	-1.2	-0.6	-0.7	-1.5	-1.0	-0.9	-1.5	-0.2	-0.3	-1.0
Illnesses of father: Heart disease	1.2	1.7	3.9	1.3	-1.2	1.2	-1.0	-0.2	-1.4	-0.8	-1.2	-1.8	-2.0	-1.3
Illnesses of siblings: Diabetes	0.9	1.0	6.0	-0.9	0.6	-0.7	1.0	-0.5	1.0	1.0	-0.6	2.4	0.5	0.2
Smoking status: Previous	0.5	0.7	3.9	-0.1	0.1	-2.0	-0.2	-1.3	-0.3	0.5	0.9	0.1	0.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.7	0.8	-1.0	-0.9	-1.1	-0.7	0.2	-0.3	-0.0	-0.1	1.9	1.0
Whole body fat-free mass	0.2	1.3	3.3	-1.3	-1.5	0.3	0.6	-1.3	-0.0	-1.2	-1.8	0.4	1.0	-1.4
Leg fat-free mass (right)	0.2	0.8	2.3	-0.9	-1.4	0.9	0.6	-0.8	-0.0	-0.7	-1.5	0.0	0.7	-1.1
Arm fat percentage (left)	1.3	5.2	19.4	-2.1	-0.4	2.0	4.4	0.4	1.9	0.3	-2.4	3.3	3.0	0.3
Average weekly red wine intake	0.3	0.4	1.5	0.1	1.2	1.1	-0.3	-0.2	0.2	0.4	0.6	-0.4	-0.4	0.6
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.2	-2.0	1.4	-1.0	0.2	-0.1	1.6	0.5	1.6	0.9	0.4	-0.1
Mood swings	1.9	3.3	11.8	0.6	-0.0	-1.7	2.2	-3.0	-0.7	-1.9	-3.4	1.1	0.2	-1.6
Loneliness, isolation	0.4	0.6	2.2	-0.4	0.6	-0.8	1.5	-1.1	-0.2	-0.7	-0.9	0.7	0.4	0.1
Long-standing illness, disability or infirmity	1.1	1.7	4.4	-0.9	-1.8	0.8	1.3	-1.1	-0.8	-1.2	-2.0	-2.1	-0.7	-0.9
Ever had bowel cancer screening	1.6	1.8	6.0	-1.3	0.9	0.5	0.4	-2.2	2.5	1.2	1.7	-1.5	-0.0	0.4
Diabetes diagnosed by doctor	0.9	1.4	6.2	-2.5	-0.5	0.2	2.1	-0.6	1.7	-0.1	0.0	-0.7	0.1	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	2.0	0.8	-0.6	0.6	-0.5	-1.4	-0.0	-0.8	-0.3	-0.8	0.3	0.3
Friendships satisfaction	1.3	1.6	7.5	-0.6	0.8	0.8	1.5	0.6	1.8	1.1	0.0	2.7	0.8	0.5
Qualifications: nursing, teaching	0.6	1.0	3.4	-1.9	0.0	0.8	-0.9	-1.3	0.2	-0.8	-0.6	1.5	-0.1	-0.8
Commuting to job workplace: Walk	1.2	1.3	4.8	-0.5	0.7	-2.0	0.3	-2.2	1.0	0.1	-0.5	0.2	-1.2	-1.3
Eye problems/disorders: Cataract	1.4	1.6	7.9	-0.7	1.4	-0.3	-1.2	1.0	0.1	0.4	0.3	-0.0	-2.8	-2.0
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	6.0	-0.5	0.2	0.2	2.4	0.3	-1.4	-1.7	-1.8	0.9	0.9	0.5
Medication for cholesterol	1.1	1.7	6.0	1.9	-0.9	0.2	-0.3	-0.5	-2.4	-1.9	-1.6	-0.4	0.4	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	7.0	0.2	-1.0	2.6	0.9	0.8	-1.3	-0.1	-0.5	0.1	-1.0	-0.1
Back pain experienced in last month	0.4	0.6	2.7	-0.8	0.2	-1.6	-1.0	0.3	-0.3	-1.1	0.1	-0.9	0.1	0.5
Mineral and other dietary supplements	2.0	2.7	7.3	-1.4	-2.6	-0.8	2.2	-1.6	-0.8	-1.4	-2.7	0.5	0.2	-1.6
Breast cancer (self-reported)	1.7	2.0	6.7	-1.8	2.6	0.7	2.2	1.8	0.6	0.7	0.4	1.0	0.1	1.1
Asthma (self-reported)	0.7	1.3	3.0	-0.4	-1.7	-0.6	0.6	-1.4	-1.7	-0.7	-1.5	-1.5	-0.8	-0.7
Osteoporosis (self-reported)	3.6	4.4	10.9	1.7	-0.3	-1.6	-2.8	-1.3	-1.7	-2.2	-0.0	-3.3	-3.2	-2.1
Osteoarthritis (self-reported)	0.4	0.5	1.1	-1.0	0.1	1.0	1.0	-0.7	0.7	-0.6	-0.2	0.9	0.2	-0.0
Medication: Aspirin	0.8	1.1	3.6	-1.2	-0.6	0.9	1.1	-0.3	0.6	1.8	-0.3	-0.6	-1.9	-0.7
Medication: Gliclazide	0.7	0.8	4.1	-2.0	-0.1	0.2	0.4	-0.9	1.4	0.1	0.5	0.4	0.7	0.4
Illnesses of father: None of the above (group 1)	0.7	0.9	4.1	-1.4	-0.3	-1.1	2.0	0.1	0.3	-0.0	-0.1	1.3	0.6	-0.6
Smoking status: Current	0.2	0.3	1.2	-1.1	-0.4	0.5	0.6	-0.1	-0.2	-0.7	-0.8	0.6	0.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.1	0.4	0.7	0.8	-0.9	-0.0	0.9	0.9	1.4	0.9	-0.1	0.6
Whole body water mass	0.2	1.2	3.3	-1.4	-1.4	0.4	0.7	-1.3	0.0	-1.2	-1.8	0.5	1.1	-1.2
Leg predicted mass (right)	0.2	0.9	2.5	-0.9	-1.4	0.9	0.6	-0.7	-0.0	-0.7	-1.6	0.0	0.7	-1.2
Arm fat mass (left)	1.3	5.3	20.2	-2.4	-1.0	1.9	4.5	-0.1	1.5	-0.2	-2.9	3.0	2.8	-0.3
Number of self-reported non-cancer illnesses	0.7	1.2	5.6	-2.4	-0.7	0.8	0.5	-1.1	1.4	0.7	0.7	-1.4	-0.5	0.3
Average weekly champagne plus white wine intake	0.7	1.0	2.6	0.3	-0.4	-1.6	-1.5	0.3	-1.0	-0.3	0.3	-0.6	-1.5	-1.5
Miserableness	1.1	1.9	5.8	0.2	-1.2	-0.7	1.8	0.5	-1.9	-1.2	-2.4	-0.1	-1.4	-1.6
Guilty feelings	0.6	0.9	2.6	-0.2	0.4	-0.2	1.1	-0.6	-0.3	-1.4	-1.5	1.0	1.6	-0.0
Wears glasses or contact lenses	0.8	1.0	4.2	-2.0	1.1	0.1	-0.9	0.7	1.0	0.2	1.3	-0.9	0.6	-0.0
Ever taken oral contraceptive pill	0.8	0.9	4.2	0.5	-0.8	-2.1	0.7	-0.7	-0.7	0.8	-0.5	0.1	-1.4	-0.8
Hearing aid user	1.0	1.1	3.9	-0.5	-0.6	-1.8	0.9	-2.0	-0.6	-0.8	-1.6	-0.5	0.2	-0.1
Mother’s age at death	1.2	1.5	5.6	-0.1	1.4	0.3	-2.1	0.1	-0.0	0.3	2.4	-1.0	-1.8	0.1
Financial situation satisfaction	0.2	0.3	1.3	0.5	-0.7	-0.0	-1.1	-0.2	-0.6	0.1	-0.1	0.1	0.9	-0.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.3	-0.3	0.6	0.0	0.6	-1.8	0.5	0.5	-0.8	1.4	-1.0	-0.6
Commuting to job workplace: Public transport	0.7	0.8	3.9	-0.7	0.4	-0.6	0.0	-0.8	-0.1	-0.8	-1.3	-0.1	-0.9	-2.0
Eye problems/disorders: Glaucoma	0.7	0.8	3.1	-0.8	0.9	-1.0	1.4	0.0	0.8	0.2	-0.0	1.8	0.6	0.5
Medication: Blood pressure	0.5	0.9	4.8	-1.4	-0.5	0.8	2.2	0.4	1.0	0.3	-0.1	-0.1	-0.4	0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.9	-0.3	-0.9	-0.4	-0.1	0.1	0.9	0.5	0.2	0.9	0.3	0.6
Supplements: Fish oil (including cod liver oil)	2.7	3.5	8.7	-0.2	2.5	1.1	-1.6	2.6	2.1	1.7	3.0	0.6	1.0	2.0
High cholesterol (Self-reported)	1.2	2.1	5.1	-1.9	1.8	1.7	2.3	0.6	1.9	1.5	-0.1	1.3	-0.1	-0.1
Medication: Bendroflumethiazide	0.5	0.7	2.1	-1.5	-0.0	-0.1	1.0	0.6	0.3	-1.1	-1.0	-0.5	0.3	-1.2
Medication: Paracetamol	1.2	1.8	8.4	-0.5	-1.8	-0.5	-0.1	0.1	-0.6	-0.8	-0.8	-1.3	-2.9	-2.2
Medication: Lisinopril	2.4	3.1	7.6	0.6	-2.8	1.7	0.7	1.6	-1.2	-0.6	-1.7	-1.8	-2.5	-2.5
Medication: Atorvastatin	0.4	0.4	1.8	-0.6	0.0	-1.3	0.6	0.3	0.2	-0.6	-0.4	-0.6	0.3	-1.2
Illnesses of father: High blood pressure	0.3	0.4	1.4	0.1	-1.2	0.8	-0.1	-0.4	0.2	0.6	0.1	-0.3	0.7	0.9
Alcohol drinker status: Never	0.9	1.0	2.6	-0.2	0.8	0.7	1.1	-1.5	0.7	1.2	0.2	-0.0	1.6	1.4
Ever smoked	0.7	1.2	5.0	-0.3	-1.2	-2.2	-0.1	-1.8	-1.1	-1.1	-0.7	0.4	0.7	-0.3
Basal metabolic rate	0.3	1.7	5.1	-1.5	-1.6	0.5	1.5	-1.0	0.2	-1.1	-2.2	1.1	1.3	-1.3
Leg fat percentage (left)	2.1	7.8	33.4	-3.4	-0.1	1.6	5.8	-0.0	2.6	0.5	-2.3	4.1	2.9	0.5
Arm fat-free mass (left)	0.4	1.8	4.7	-1.7	-1.1	0.2	1.6	-1.5	0.1	-1.4	-2.2	1.0	0.7	-1.7
Number of operations (self-reported)	0.5	0.7	2.6	-1.2	-0.1	-0.4	1.6	-1.0	-0.0	-1.0	-1.0	0.2	-0.5	-0.4
Average weekly beer plus cider intake	0.9	1.3	4.3	-0.4	-0.3	0.3	1.1	1.6	-0.5	0.1	-0.8	1.5	2.1	1.7
Irritability	2.0	3.4	11.4	0.7	-0.6	-1.2	-0.4	-1.3	-2.9	-3.4	-2.9	-0.8	-0.5	-2.1
Risk taking	0.8	1.1	3.9	0.7	0.0	-0.7	-1.9	-0.4	-0.5	0.1	1.0	0.2	1.7	2.0
Ever had prostate specific antigen (PSA) test	1.9	2.1	5.6	-1.3	1.4	1.5	-1.0	-0.9	-0.5	-2.4	-0.1	-2.1	-1.7	-1.7
Fractured/broken bones in last 5 years	1.6	2.1	5.3	1.4	-1.9	-0.6	-0.0	-1.1	-1.3	-1.0	-1.3	-1.5	-2.3	-1.9
Age started oral contraceptive pill	1.5	1.9	6.1	1.2	2.2	-0.7	-0.5	-0.6	0.3	0.3	2.5	-1.4	-2.1	0.5
Diastolic blood pressure, automated reading	0.7	2.2	6.2	-0.4	-2.2	0.4	1.9	0.4	0.1	-1.7	-2.5	0.7	-0.4	-2.5
Ever depressed for a whole week	1.2	1.5	9.0	-0.4	0.0	3.0	0.3	0.4	1.6	0.7	0.5	1.1	1.4	0.4
Unable to work because of sickness or disability	0.8	1.0	2.8	0.2	0.7	-0.4	-1.0	0.7	0.1	-0.7	1.3	-1.7	0.9	1.7
Commuting to job workplace: Cycle	0.6	0.8	3.7	0.9	-1.9	-0.6	0.2	-0.4	-1.3	-0.6	-0.4	-0.7	-0.8	-0.2
Myopia	1.3	1.9	6.1	-1.7	-1.3	-0.0	-1.0	0.3	2.5	1.3	1.4	0.6	2.1	1.1
Vascular/heart problems diagnosed by doctor	1.0	2.6	7.0	2.6	-1.2	-1.8	-2.5	-0.6	-2.3	-0.8	-1.0	-1.4	-0.8	-1.0
Cholesterol lowering medication	0.6	0.8	3.0	-0.2	1.7	0.2	0.7	1.2	0.9	1.0	-0.1	1.3	-0.9	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.7	-0.4	0.3	-0.8	0.9	-1.7	-0.3	-0.1	-0.3	-0.9	0.6	0.8
Pain experienced in last month	0.4	0.6	1.4	1.2	-0.6	0.9	0.0	1.0	0.6	1.1	-0.1	-0.1	1.0	0.4
Supplements: Calcium	0.5	0.6	1.6	0.4	-0.5	1.2	-0.2	0.4	1.0	0.7	0.2	0.5	0.8	1.3
Basal cell carcinoma (self-reported)	0.4	0.5	1.9	-0.5	1.1	0.3	0.6	1.0	1.4	0.8	0.6	0.3	-0.2	-0.1
Heart attack/myocardial infarction (self-reported)	1.4	1.8	6.9	-2.2	2.6	1.2	0.4	-0.2	1.6	0.8	1.1	1.3	0.6	0.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	1.5	0.6	-0.1	0.5	-0.5	-0.1	0.2	-0.9	-0.3	-0.4	-0.6	-1.2
Heart disease (siblings)	0.1	0.1	0.5	0.1	-0.3	-0.2	0.1	0.7	0.2	-0.3	-0.0	-0.3	-0.2	-0.0
Alcohol drinker status: Previous	0.9	1.1	3.4	-0.4	-0.9	0.2	-1.8	-1.7	-0.8	0.6	1.2	-0.9	0.4	1.0
Pack years of smoking	0.7	1.1	3.5	-0.8	0.4	-0.5	0.5	1.4	-0.9	-1.2	-0.5	-0.3	-1.9	-1.5
Impedance of whole body	0.3	1.3	6.8	1.1	1.7	-0.9	-0.6	2.6	0.6	0.3	0.9	0.5	-0.9	0.1
Leg fat mass (left)	1.7	6.6	26.9	-2.9	-0.9	1.8	5.2	-0.2	2.0	0.1	-2.7	3.7	2.8	0.0
Arm predicted mass (left)	0.4	2.1	5.6	-1.9	-1.4	0.5	2.0	-1.4	-0.0	-1.3	-2.4	1.1	0.9	-1.5