TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat percentage (right)
:
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chr1:112,312,154-113,857,970
Best TWAS P=2.1e-08 · Best GWAS P=9.52e-09 conditioned to 1
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
MOV10
0.06
0.06
lasso
7
0.05
9.4e-06
-5.7
-5.6
2.1e-08
0.97
0.00
0.99
TRUE
1
GTEx
Brain Frontal Cortex BA9
WNT2B
0.29
0.28
lasso
3
0.29
2.6e-08
-5.0
-5.4
6.7e-08
0.94
0.02
0.98
FALSE
2
GTEx
Pituitary
ST7L
0.31
0.18
lasso
7
0.18
3.0e-05
-4.9
-5.4
7.8e-08
0.89
0.01
0.98
FALSE