Best TWAS P=2.09e-08 · Best GWAS P=1.86e-06 conditioned to 0.507
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | TSPAN2 | 0.03 | 0.01 | bslmm | 494 | 0.02 | 9.6e-07 | -4.5 | -5.1 | 2.9e-07 | 0.55 | 0.01 | 0.91 | FALSE |
2 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | SIKE1 | 0.44 | 0.09 | lasso | 7 | 0.13 | 1.9e-04 | -4.3 | -5.6 | 2.1e-08 | 0.78 | 0.00 | 0.07 | TRUE |