[Hub]/) : Traits : Leg fat percentage (right) :

chr18:12,090,696-13,822,256

Best TWAS P=1.08e-09 · Best GWAS P=1.25e-09 conditioned to 0.0136

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum CEP192 0.38 0.35 lasso 4 0.43 3.0e-24 -4.8 -5.6 1.6e-08 -0.66 0.80 0.20 FALSE
2 GTEx Brain Cerebellum CEP192 0.52 0.44 enet 31 0.52 5.6e-18 -4.8 -5.1 2.8e-07 -0.67 0.79 0.21 FALSE
3 GTEx Brain Cortex CEP192 0.40 0.26 lasso 6 0.26 9.9e-08 -4.8 -5.5 5.1e-08 -0.67 0.60 0.38 FALSE
4 GTEx Brain Hippocampus CEP192 0.43 0.35 lasso 9 0.44 9.8e-12 -4.8 -5.9 2.9e-09 -0.76 0.27 0.72 FALSE
5 GTEx Brain Hypothalamus CEP192 0.35 0.33 enet 29 0.33 1.8e-08 -4.5 -5.4 8.5e-08 -0.70 0.66 0.32 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia CEP192 0.38 0.28 lasso 9 0.28 4.8e-08 -4.8 -5.3 1.4e-07 -0.70 0.32 0.66 FALSE
7 GTEx Brain Nucleus accumbens basal ganglia PTPN2 0.32 0.02 lasso 10 0.05 2.2e-02 5.7 6.1 1.1e-09 0.71 0.06 0.41 TRUE
8 GTEx Brain Putamen basal ganglia CEP192 0.50 0.39 lasso 5 0.36 2.4e-09 -4.8 -5.3 1.3e-07 -0.66 0.41 0.55 FALSE
9 GTEx Colon Sigmoid CEP192 0.33 0.32 enet 23 0.32 3.6e-12 -4.8 -5.4 5.3e-08 -0.69 0.77 0.23 FALSE
10 GTEx Colon Transverse CEP192 0.45 0.54 lasso 8 0.57 1.2e-32 -4.7 -5.3 1.1e-07 -0.67 0.83 0.17 FALSE
11 GTEx Heart Atrial Appendage CEP192 0.29 0.28 lasso 5 0.26 4.3e-12 -4.7 -5.2 2.2e-07 -0.66 0.80 0.20 FALSE
12 GTEx Liver CEP192 0.41 0.29 lasso 6 0.41 1.6e-12 -4.8 -5.5 5.0e-08 -0.72 0.64 0.36 FALSE
13 GTEx Pancreas CEP192 0.44 0.37 lasso 8 0.44 3.1e-20 -4.7 -5.4 6.2e-08 -0.67 0.74 0.26 FALSE
14 GTEx Pituitary CEP192 0.51 0.24 enet 29 0.39 1.0e-10 -4.7 -5.7 1.3e-08 -0.79 0.09 0.91 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic CEP192 0.34 0.35 enet 20 0.40 1.6e-23 -4.8 -5.3 1.0e-07 -0.68 0.80 0.19 FALSE
16 ROSMAP Brain Pre-frontal Cortex SEH1L 0.04 0.05 lasso 1 0.03 2.6e-05 5.5 -5.5 3.8e-08 -0.84 0.08 0.90 FALSE
17 ROSMAP Brain Pre-frontal Cortex CEP192 0.30 0.42 enet 46 0.45 4.1e-64 -4.7 -5.7 1.3e-08 -0.74 0.80 0.20 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma CEP192 0.09 0.14 blup 85 0.14 8.4e-16 -4.8 -5.5 3.2e-08 -0.72 0.82 0.18 FALSE
19 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CEP192 0.09 0.07 blup 84 0.09 2.1e-06 -4.5 -5.3 1.0e-07 -0.72 0.37 0.61 FALSE