Best TWAS P=1.96e-10 · Best GWAS P=1.78e-10 conditioned to 0.2
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | BAIAP2 | 0.36 | 0.01 | enet | 22 | 0.02 | 8.5e-02 | 3.0 | -6.2 | 6.5e-10 | 0.43 | 0.04 | 0.14 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | DUS1L | 0.05 | 0.00 | enet | 11 | 0.01 | 9.7e-02 | 4.2 | -5.9 | 4.6e-09 | 0.11 | 0.03 | 0.27 | TRUE |
3 | GTEx | Muscle Skeletal | RPTOR | 0.14 | 0.05 | enet | 27 | 0.09 | 8.4e-09 | -5.3 | -6.4 | 2.0e-10 | 0.62 | 0.48 | 0.51 | TRUE |
4 | GTEx | Muscle Skeletal | CTD-2561B21.4 | 0.06 | 0.04 | lasso | 7 | 0.03 | 2.3e-04 | -5.1 | -5.6 | 1.7e-08 | 0.64 | 0.14 | 0.78 | FALSE |