TWAS
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat percentage (right)
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chr2:46,599,373-47,102,655
Best TWAS P=3.6e-08 · Best GWAS P=9.17e-11 conditioned to 0.000106
46.6M
46.7M
46.8M
46.9M
47M
47.1M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Colon Adenocarcinoma
CRIPT
0.10
0.06
blup
66
0.07
5.6e-05
-3.9
-5.5
3.6e-08
0.63
0.47
0.24
TRUE
2
The Cancer Genome Atlas
Rectum Adenocarcinoma
CRIPT
0.25
0.10
enet
7
0.15
1.9e-04
-4.2
-5.3
9.4e-08
0.62
0.05
0.20
FALSE