Best TWAS P=3.6e-08 · Best GWAS P=9.17e-11 conditioned to 0.000106
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Colon Adenocarcinoma | CRIPT | 0.10 | 0.06 | blup | 66 | 0.07 | 5.6e-05 | -3.9 | -5.5 | 3.6e-08 | 0.63 | 0.47 | 0.24 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | CRIPT | 0.25 | 0.10 | enet | 7 | 0.15 | 1.9e-04 | -4.2 | -5.3 | 9.4e-08 | 0.62 | 0.05 | 0.20 | FALSE |