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Traits
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Leg fat percentage (right)
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chr2:47,845,523-49,300,234
Best TWAS P=1.68e-08 · Best GWAS P=3.33e-08 conditioned to 0.191
47.8M
48M
48.2M
48.4M
48.6M
48.8M
49M
49.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adrenal Gland
FOXN2
0.24
0.11
lasso
6
0.16
2.8e-06
-4.9
5.6
1.7e-08
-0.86
0.02
0.97
TRUE
3
GTEx
Skin Not Sun Exposed Suprapubic
FOXN2
0.14
0.06
lasso
3
0.08
2.2e-05
4.6
5.2
1.9e-07
-0.39
0.24
0.68
FALSE
5
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
KLRAQ1
0.15
0.08
lasso
7
0.13
3.6e-14
-5.4
-5.2
2.1e-07
0.79
0.00
1.00
FALSE
2
GTEx
Cells Transformed fibroblasts
FOXN2
0.18
0.15
lasso
4
0.14
7.3e-11
4.6
5.1
2.8e-07
-0.45
0.24
0.75
FALSE
4
ROSMAP
Brain Pre-frontal Cortex
FOXN2
0.26
0.21
lasso
6
0.21
2.4e-26
4.6
5.1
3.1e-07
-0.44
0.25
0.74
FALSE