[Hub]/) : Traits : Leg fat percentage (right) : ← →

chr9:115,320,787-116,752,771

Best TWAS P=1.42e-09 · Best GWAS P=4.57e-09 conditioned to 0.656

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	GTEx	Small Intestine Terminal Ileum	PRPF4	0.50	0.30	enet	14	0.33	2.9e-08	5.9	6.1	1.4e-09	0.94	0.00	1.00	TRUE
6	GTEx	Breast Mammary Tissue	PRPF4	0.27	0.22	lasso	3	0.20	1.2e-10	5.8	5.9	3.0e-09	0.97	0.00	1.00	FALSE
12	GTEx	Liver	PRPF4	0.29	0.14	lasso	7	0.12	4.0e-04	5.8	5.9	3.5e-09	0.93	0.01	0.99	FALSE
22	GTEx	Testis	PRPF4	0.33	0.17	enet	7	0.18	1.8e-08	5.7	5.9	4.0e-09	0.99	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PRPF4	0.10	0.07	lasso	6	0.07	7.2e-05	5.9	5.9	4.2e-09	0.99	0.00	1.00	FALSE
9	GTEx	Colon Transverse	PRPF4	0.22	0.20	lasso	2	0.17	2.3e-08	5.9	5.9	4.6e-09	1.00	0.00	1.00	FALSE
21	GTEx	Stomach	PRPF4	0.47	0.40	lasso	4	0.39	5.8e-20	5.8	5.8	4.9e-09	1.00	0.00	1.00	FALSE
27	YFS	Blood	CDC26	0.07	0.09	lasso	8	0.09	3.9e-27	5.8	-5.8	4.9e-09	-0.97	0.00	1.00	FALSE
2	GTEx	Adrenal Gland	PRPF4	0.28	0.26	lasso	5	0.21	4.2e-08	5.9	5.8	5.0e-09	0.99	0.00	1.00	FALSE
14	GTEx	Nerve Tibial	PRPF4	0.21	0.21	lasso	3	0.23	1.4e-16	5.9	5.8	5.7e-09	1.00	0.00	1.00	FALSE
11	GTEx	Esophagus Muscularis	PRPF4	0.20	0.13	enet	7	0.13	1.6e-08	5.8	5.8	5.8e-09	0.97	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	PRPF4	0.09	0.13	lasso	3	0.12	3.5e-12	5.8	5.8	5.9e-09	0.99	0.00	1.00	FALSE
24	GTEx	Thyroid	PRPF4	0.53	0.51	lasso	6	0.52	1.9e-46	5.8	5.8	7.3e-09	0.98	0.00	1.00	FALSE
10	GTEx	Esophagus Mucosa	PRPF4	0.15	0.18	lasso	2	0.17	3.1e-11	5.8	5.8	7.4e-09	0.98	0.00	1.00	FALSE
15	GTEx	Pancreas	PRPF4	0.38	0.39	lasso	6	0.36	2.6e-16	5.8	5.8	7.4e-09	0.98	0.00	1.00	FALSE
7	GTEx	Breast Mammary Tissue (Female)	PRPF4	0.12	0.04	lasso	1	0.01	1.9e-01	5.8	5.8	7.7e-09	0.98	0.01	0.84	FALSE
20	GTEx	Spleen	PRPF4	0.40	0.37	lasso	1	0.37	1.9e-10	5.7	5.7	9.4e-09	0.98	0.00	1.00	FALSE
18	GTEx	Skin Sun Exposed Lower leg	PRPF4	0.17	0.11	lasso	4	0.10	6.0e-09	5.8	5.7	9.6e-09	0.99	0.00	1.00	FALSE
3	GTEx	Artery Aorta	PRPF4	0.28	0.25	lasso	5	0.22	1.2e-12	5.7	5.7	1.2e-08	0.97	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	PRPF4	0.17	0.13	lasso	3	0.11	2.1e-09	5.8	5.6	1.8e-08	0.97	0.00	1.00	FALSE
16	GTEx	Pituitary	PRPF4	0.51	0.38	lasso	5	0.34	1.8e-09	5.7	5.6	1.9e-08	0.98	0.00	1.00	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	PRPF4	0.23	0.24	lasso	2	0.20	5.7e-07	5.8	5.6	2.3e-08	0.96	0.00	0.99	FALSE
25	GTEx	Thyroid	CDC26	0.24	0.19	lasso	7	0.22	7.3e-17	5.7	-5.6	2.6e-08	-0.92	0.01	0.99	FALSE
13	GTEx	Lung	PRPF4	0.26	0.27	lasso	4	0.30	2.5e-23	5.8	5.5	3.2e-08	0.98	0.00	1.00	FALSE
17	GTEx	Prostate	PRPF4	0.46	0.42	lasso	4	0.45	1.3e-12	5.9	5.5	3.4e-08	0.97	0.00	1.00	FALSE
5	GTEx	Brain Hypothalamus	PRPF4	0.35	0.23	lasso	7	0.27	5.9e-07	5.8	5.5	5.0e-08	0.94	0.01	0.99	FALSE
4	GTEx	Brain Cortex	PRPF4	0.35	0.05	lasso	7	0.06	7.6e-03	5.7	5.4	6.5e-08	0.86	0.02	0.89	FALSE
23	GTEx	Testis	CDC26	0.18	0.11	enet	9	0.14	8.7e-07	4.0	-5.3	9.1e-08	-0.89	0.05	0.95	FALSE
26	METSIM	Adipose	PRPF4	0.10	0.10	lasso	8	0.08	1.4e-12	4.7	5.1	3.1e-07	0.87	0.02	0.98	FALSE