TWAS
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Genes
Traits
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Traits
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Leg fat percentage (right)
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chr9:98,302,535-99,734,369
Best TWAS P=2.64e-08 · Best GWAS P=1.81e-08 conditioned to 1
98.4M
98.6M
98.8M
99M
99.2M
99.4M
99.6M
99.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
HABP4
0.05
0.08
lasso
5
0.08
6.9e-09
-5.6
5.6
2.6e-08
-1.00
0.01
0.99
TRUE
1
GTEx
Nerve Tibial
HSD17B3
0.14
0.00
enet
20
0.00
2.4e-01
-4.8
-5.4
5.8e-08
0.69
0.05
0.63
FALSE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CDC14B
0.03
0.02
blup
42
0.02
2.1e-03
-5.1
5.2
1.8e-07
-0.93
0.02
0.79
FALSE