Best TWAS P=2.64e-08 · Best GWAS P=1.81e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | HSD17B3 | 0.14 | 0.00 | enet | 20 | 0.00 | 2.4e-01 | -4.8 | -5.4 | 5.8e-08 | 0.69 | 0.05 | 0.63 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CDC14B | 0.03 | 0.02 | blup | 42 | 0.02 | 2.1e-03 | -5.1 | 5.2 | 1.8e-07 | -0.93 | 0.02 | 0.79 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HABP4 | 0.05 | 0.08 | lasso | 5 | 0.08 | 6.9e-09 | -5.6 | 5.6 | 2.6e-08 | -1.00 | 0.01 | 0.99 | TRUE |