[Hub]/) : Traits : Leg fat mass (right) : ← →

chr11:26,818,083-29,054,545

Best TWAS P=5.59e-26 · Best GWAS P=3.96e-33 conditioned to 7.05e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LIN7C	0.08	0.06	lasso	1	0.04	4.1e-04	10.541	10.5	5.6e-26	0.65	0.75	0.13	TRUE
2	GTEx	Brain Putamen basal ganglia	BDNF-AS	0.22	0.17	lasso	4	0.13	5.5e-04	-6.840	8.2	2.6e-16	0.33	0.23	0.05	FALSE
3	GTEx	Cells Transformed fibroblasts	LIN7C	0.26	0.22	lasso	6	0.25	1.4e-18	10.541	8.6	5.8e-18	0.64	1.00	0.00	FALSE
4	GTEx	Esophagus Muscularis	LIN7C	0.14	0.08	enet	11	0.07	5.4e-05	3.278	7.4	1.8e-13	0.62	0.70	0.15	FALSE
5	GTEx	Liver	METTL15	0.18	0.05	lasso	3	0.09	1.9e-03	0.009	-7.8	4.1e-15	-0.69	0.02	0.83	FALSE
6	GTEx	Nerve Tibial	LIN7C	0.18	0.08	enet	27	0.12	4.2e-09	10.541	6.0	2.5e-09	0.56	0.65	0.32	FALSE
7	GTEx	Thyroid	LIN7C	0.08	0.04	lasso	4	0.04	6.0e-04	10.541	10.1	7.8e-24	0.71	0.48	0.41	FALSE
8	NTR	Blood	LIN7C	0.01	0.00	lasso	3	0.01	2.2e-03	10.814	-10.5	8.4e-26	-0.74	0.10	0.80	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	METTL15	0.04	0.03	blup	364	0.03	4.6e-05	-2.967	-5.3	9.8e-08	-0.19	0.72	0.01	TRUE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LIN7C	0.04	0.01	lasso	3	0.02	1.0e-02	-1.979	6.4	1.8e-10	0.48	0.02	0.83	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	LIN7C	0.10	0.03	blup	32	0.08	2.8e-05	10.902	8.3	8.7e-17	0.56	0.01	0.96	TRUE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LIN7C	0.05	0.02	lasso	3	0.03	2.9e-04	10.956	9.8	1.8e-22	0.65	0.00	0.99	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIN7C	0.09	0.12	lasso	2	0.12	2.6e-13	3.386	5.8	6.5e-09	0.53	0.93	0.07	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	LIN7C	0.02	0.02	enet	3	0.02	5.6e-03	1.845	5.2	2.4e-07	0.54	0.01	0.73	TRUE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	BDNFOS	0.03	0.01	blup	83	0.02	1.4e-03	1.843	5.2	2.2e-07	-0.12	0.34	0.02	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	LIN7C	0.09	0.10	enet	7	0.09	8.1e-09	3.386	5.2	1.8e-07	0.49	0.93	0.07	FALSE