[Hub]/) : Traits : Leg fat mass (right) : ← →

chr11:29,646,947-31,288,160

Best TWAS P=2.11e-09 · Best GWAS P=1.95e-09 conditioned to 0.299

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum ARL14EP 0.33 0.25 lasso 10 0.26 3.7e-08 5.6 -5.9 3.1e-09 -0.96 0.01 0.99 FALSE
2 GTEx Esophagus Gastroesophageal Junction ARL14EP 0.15 0.14 lasso 3 0.11 1.2e-04 5.6 -5.7 9.3e-09 -0.94 0.01 0.98 FALSE
3 GTEx Esophagus Muscularis ARL14EP 0.18 0.20 lasso 8 0.19 9.5e-12 6.0 -6.0 2.1e-09 -0.95 0.01 0.99 TRUE
4 GTEx Nerve Tibial ARL14EP 0.19 0.17 enet 22 0.18 4.2e-13 5.9 -5.1 2.8e-07 -0.87 0.01 0.99 FALSE
5 GTEx Pancreas ARL14EP 0.16 0.08 lasso 6 0.07 1.0e-03 5.4 -5.9 3.6e-09 -0.91 0.01 0.96 FALSE
6 GTEx Pituitary ARL14EP 0.30 0.28 lasso 4 0.22 3.0e-06 5.8 -5.9 3.2e-09 -0.82 0.02 0.96 FALSE
7 ROSMAP Brain Pre-frontal Cortex MPPED2 0.25 0.29 lasso 7 0.29 4.4e-37 5.0 -5.1 3.1e-07 -0.66 0.17 0.83 FALSE
8 ROSMAP Brain Pre-frontal Cortex ARL14EP 0.08 0.07 enet 13 0.08 5.3e-10 6.0 -5.3 8.6e-08 -0.95 0.01 0.99 FALSE