Best TWAS P=7.71e-09 · Best GWAS P=4.6e-09 conditioned to 0.092
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FARP1 | 0.10 | 0.05 | enet | 5 | 0.05 | 1.4e-06 | -5.5 | 5.5 | 4.4e-08 | -0.94 | 0.02 | 0.98 | FALSE |
2 | GTEx | Adipose Subcutaneous | STK24 | 0.18 | 0.06 | lasso | 8 | 0.08 | 2.4e-07 | -4.4 | -5.2 | 2.1e-07 | 0.75 | 0.03 | 0.97 | FALSE |
3 | GTEx | Artery Tibial | STK24 | 0.12 | 0.10 | lasso | 3 | 0.08 | 8.4e-07 | -5.3 | -5.2 | 1.7e-07 | 0.85 | 0.09 | 0.91 | FALSE |
4 | GTEx | Esophagus Mucosa | FARP1-AS1 | 0.11 | 0.03 | lasso | 2 | 0.04 | 1.7e-03 | -5.5 | -5.6 | 2.1e-08 | 0.99 | 0.01 | 0.98 | FALSE |
5 | NTR | Blood | FARP1 | 0.02 | 0.01 | lasso | 3 | 0.01 | 4.3e-04 | -5.7 | -5.8 | 7.7e-09 | 0.87 | 0.01 | 0.98 | TRUE |