[Hub]/) : Traits : Leg fat mass (right) : ← →

chr15:84,151,637-85,883,064

Best TWAS P=2.23e-09 · Best GWAS P=4.59e-13 conditioned to 0.00818

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC388152 0.14 0.14 enet 20 0.18 6.7e-22 3.47 -5.3 1.3e-07 0.52 1.00 0.00 TRUE
2 GTEx Artery Tibial SCAND2P 0.12 0.05 enet 16 0.08 8.7e-07 -2.75 -5.2 1.8e-07 0.38 0.36 0.44 TRUE
3 GTEx Brain Cortex GOLGA6L4 0.42 0.21 lasso 7 0.28 2.8e-08 -5.48 -5.9 4.8e-09 0.65 0.18 0.74 FALSE
4 GTEx Breast Mammary Tissue (Male) GOLGA6L4 0.23 0.07 lasso 2 0.12 8.3e-04 -5.48 -5.4 5.1e-08 0.57 0.07 0.32 FALSE
5 GTEx Cells Transformed fibroblasts AC103965.1 0.15 0.09 lasso 7 0.11 1.3e-08 3.49 -5.2 1.6e-07 0.56 0.69 0.30 FALSE
6 GTEx Colon Transverse AC103965.1 0.15 0.07 enet 33 0.06 7.1e-04 -5.35 -5.7 1.5e-08 0.50 0.10 0.49 FALSE
7 GTEx Colon Transverse CSPG4P11 0.10 0.10 lasso 4 0.08 1.2e-04 -5.35 -5.3 1.1e-07 0.40 0.25 0.04 FALSE
8 GTEx Esophagus Mucosa CSPG4P11 0.21 0.01 enet 28 0.08 3.7e-06 -5.35 -5.2 2.1e-07 0.56 0.64 0.28 FALSE
9 GTEx Esophagus Muscularis UBE2Q2P1 0.34 0.03 lasso 7 0.15 1.9e-09 2.82 6.0 2.2e-09 -0.42 0.31 0.35 TRUE
10 GTEx Pancreas RP11-182J1.16 0.08 -0.01 enet 11 -0.01 7.9e-01 -5.35 -5.3 1.4e-07 0.62 0.03 0.48 FALSE
11 GTEx Prostate RP11-182J1.16 0.24 0.06 enet 27 0.08 6.2e-03 -0.11 -5.3 1.2e-07 0.48 0.07 0.30 FALSE
12 GTEx Prostate CSPG4P11 0.34 0.07 enet 13 0.18 2.3e-05 -2.05 -5.5 3.1e-08 0.42 0.06 0.68 FALSE
13 GTEx Skin Sun Exposed Lower leg AC103965.1 0.33 0.17 enet 24 0.23 4.8e-19 3.45 -5.6 2.2e-08 0.50 1.00 0.00 TRUE
14 GTEx Spleen GOLGA6L4 0.55 0.20 enet 19 0.40 2.6e-11 -5.42 -5.8 7.2e-09 0.54 0.87 0.04 FALSE
15 GTEx Whole Blood GOLGA6L4 0.12 0.08 enet 16 0.11 2.1e-10 -4.36 -5.6 2.6e-08 0.58 0.81 0.19 FALSE