TWAS hub - CSPG4P11

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1850	0.0580	6.0e-12	0.169	NA	0.167	NA	0.195	9.7e-14	NA	1.4e-13	NA	7.9e-16
2	GTEx	Adipose Visceral Omentum	0.1450	0.0510	7.8e-06	0.073	NA	0.087	NA	0.085	1.3e-04	NA	2.9e-05	NA	3.7e-05
3	GTEx	Adrenal Gland	0.1385	0.0645	1.3e-03	-0.006	NA	0.038	NA	0.009	6.3e-01	NA	1.7e-02	NA	1.5e-01
4	GTEx	Artery Aorta	0.1090	0.0460	1.7e-04	0.098	NA	0.070	NA	0.081	4.7e-06	NA	1.0e-04	NA	3.1e-05
5	GTEx	Artery Coronary	0.1750	0.0930	5.2e-03	0.020	NA	0.106	NA	0.063	6.7e-02	NA	2.0e-04	NA	3.6e-03
6	GTEx	Artery Tibial	0.1555	0.0395	2.4e-15	0.242	NA	0.221	NA	0.234	6.1e-19	NA	2.9e-17	NA	3.0e-18
7	GTEx	Brain Cerebellar Hemisphere	0.3030	0.1130	2.1e-04	0.212	NA	0.111	NA	0.158	3.9e-06	NA	8.7e-04	NA	7.6e-05
8	GTEx	Brain Cerebellum	0.2800	0.0800	2.1e-06	0.233	NA	0.252	NA	0.275	1.6e-07	NA	4.5e-08	NA	9.0e-09
9	GTEx	Breast Mammary Tissue	0.0850	0.0370	1.1e-03	0.076	NA	0.034	NA	0.051	1.0e-04	NA	7.1e-03	NA	1.3e-03
10	GTEx	Breast Mammary Tissue (Male)	0.0453	0.0485	2.0e-01	0.024	NA	-0.013	NA	0.029	9.4e-02	NA	8.7e-01	NA	7.1e-02
11	GTEx	Breast Mammary Tissue (Female)	0.1715	0.0641	5.8e-04	0.153	NA	0.105	NA	0.103	2.6e-05	NA	5.1e-04	NA	5.4e-04
12	GTEx	Cells Transformed fibroblasts	0.1900	0.0580	1.5e-11	0.181	NA	0.170	NA	0.166	1.4e-13	NA	9.8e-13	NA	1.9e-12
13	GTEx	Colon Sigmoid	0.1900	0.0920	1.4e-03	0.013	NA	0.041	NA	0.021	1.1e-01	NA	1.4e-02	NA	6.0e-02
14	GTEx	Colon Transverse	0.0960	0.0480	6.0e-03	0.101	NA	0.069	NA	0.080	1.6e-05	NA	3.4e-04	NA	1.2e-04
15	GTEx	Esophagus Gastroesophageal Junction	0.1750	0.0960	2.6e-03	0.057	NA	0.055	NA	0.059	4.1e-03	NA	4.6e-03	NA	3.5e-03
16	GTEx	Esophagus Mucosa	0.2110	0.0650	1.2e-07	0.012	NA	0.082	NA	0.077	4.6e-02	NA	3.7e-06	NA	7.9e-06
17	GTEx	Esophagus Muscularis	0.1210	0.0410	3.1e-07	0.164	NA	0.157	NA	0.180	3.5e-10	NA	8.4e-10	NA	4.0e-11
18	GTEx	Heart Atrial Appendage	0.1210	0.0460	2.5e-05	0.082	NA	0.073	NA	0.096	1.6e-04	NA	3.6e-04	NA	4.2e-05
19	GTEx	Heart Left Ventricle	0.1078	0.0524	1.5e-03	0.025	NA	-0.005	NA	0.003	1.7e-02	NA	7.6e-01	NA	2.2e-01
20	GTEx	Muscle Skeletal	0.1383	0.0427	1.7e-08	0.073	NA	0.061	NA	0.083	1.2e-07	NA	1.3e-06	NA	1.4e-08
21	GTEx	Nerve Tibial	0.2318	0.0536	5.6e-17	0.234	NA	0.251	NA	0.270	1.3e-16	NA	8.0e-18	NA	3.0e-19
22	GTEx	Ovary	0.2120	0.0920	4.7e-04	0.171	NA	0.146	NA	0.182	5.6e-05	NA	2.0e-04	NA	3.1e-05
23	GTEx	Prostate	0.3370	0.1130	4.1e-05	0.072	NA	0.184	NA	0.070	7.3e-03	NA	2.2e-05	NA	7.8e-03
24	GTEx	Skin Not Sun Exposed Suprapubic	0.2870	0.0760	3.2e-09	0.074	NA	0.133	NA	0.127	6.7e-05	NA	9.6e-08	NA	1.9e-07
25	GTEx	Skin Sun Exposed Lower leg	0.1760	0.0460	3.7e-12	0.070	NA	0.187	NA	0.192	1.8e-06	NA	2.4e-15	NA	9.1e-16
26	GTEx	Thyroid	0.1700	0.0450	2.0e-11	0.078	NA	0.141	NA	0.118	1.5e-06	NA	6.1e-11	NA	2.5e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Bipolar Disorder or Schizophrenia	16.9	41.1	59.6	7.5	6.8	4.3	7.6	6.1	7.2	-7.3	-7.5	6.6	3.3	4.8	7.2	5.4	4.3	6.5	5.5	7.6	7.0	7.7	6.6	6.8	7.1	3.9	6.5	6.0	6.6
Comparative height size at age 10	15.6	86.1	156.2	-10.8	-7.5	-7.8	-10.4	-9.8	-12.5	11.2	9.6	-7.5	-10.9	-3.7	-10.1	-8.7	-6.5	-10.4	-10.2	-10.1	-9.0	-10.0	-8.2	-10.0	-8.1	-7.9	-8.5	-8.0	-9.7
Forced expiratory volume in 1-second (FEV1), predicted	15.0	31.2	46.7	-6.4	-5.7	-4.2	-6.2	-4.4	-6.8	6.3	6.1	-5.5	-5.1	-4.2	-5.7	-4.5	-4.2	-5.9	-5.4	-6.2	-6.0	-6.1	-5.5	-5.7	-5.9	-4.7	-5.6	-5.6	-6.1
Impedance of leg (right)	13.9	67.4	151.3	-9.6	-5.6	-6.7	-9.3	-7.6	-12.3	10.1	8.0	-5.5	-11.3	-1.4	-8.1	-7.4	-5.2	-9.8	-10.9	-8.6	-7.5	-8.6	-6.5	-8.8	-6.8	-8.2	-7.0	-6.1	-8.9
Standing height	13.9	138.3	239.5	-13.8	-9.6	-9.4	-12.9	-12.6	-15.5	13.4	11.9	-9.2	-14.0	-4.8	-12.6	-10.7	-9.8	-12.8	-13.3	-12.5	-11.1	-12.5	-10.5	-11.8	-10.3	-11.4	-10.9	-11.0	-12.8
Impedance of whole body	13.6	69.1	144.0	-9.4	-6.0	-6.8	-9.3	-8.3	-12.0	10.5	8.2	-5.8	-11.8	-1.8	-8.3	-8.2	-4.8	-10.2	-10.1	-8.8	-7.7	-8.7	-6.6	-9.2	-7.2	-7.6	-6.7	-5.9	-9.0
Schizophrenia (2018)	12.7	26.4	36.6	6.0	5.1	3.9	6.0	5.0	6.0	-6.0	-5.9	5.0	3.1	3.4	5.8	4.8	3.7	5.4	5.0	6.0	5.5	6.0	5.2	5.6	5.5	3.4	5.0	4.3	5.0
Height	12.5	240.6	436.8	-18.1	-12.2	-11.8	-16.9	-16.5	-20.9	18.2	15.6	-11.6	-18.4	-5.8	-16.7	-14.0	-13.3	-17.2	-17.1	-16.3	-14.2	-16.3	-13.3	-15.7	-12.9	-16.3	-14.6	-14.7	-17.5
Impedance of leg (left)	12.5	60.9	136.9	-9.1	-5.3	-6.3	-8.9	-7.4	-11.7	9.7	7.7	-5.1	-11.0	-1.1	-7.7	-7.5	-5.0	-9.4	-10.2	-8.3	-7.1	-8.1	-6.1	-8.3	-6.5	-7.5	-6.4	-5.6	-8.2
Impedance of arm (left)	11.9	55.2	110.2	-8.3	-5.5	-6.3	-8.3	-7.5	-10.5	9.5	7.5	-5.3	-10.5	-1.8	-7.6	-7.5	-3.8	-9.2	-8.7	-7.8	-7.0	-7.8	-6.0	-8.4	-6.4	-6.1	-6.1	-5.3	-8.0
Impedance of arm (right)	11.0	51.1	106.1	-7.9	-5.2	-6.1	-7.8	-7.1	-10.1	9.2	7.1	-5.0	-10.3	-1.8	-7.2	-7.1	-3.6	-9.1	-8.7	-7.3	-6.7	-7.3	-5.8	-8.1	-6.0	-6.1	-6.0	-5.3	-7.9
Schizophrenia (2014)	10.1	22.2	32.5	5.5	5.0	3.5	5.6	4.4	5.6	-5.5	-5.7	4.7	2.9	3.0	5.3	4.9	3.1	5.0	4.4	5.6	5.1	5.4	4.7	5.1	5.1	2.8	4.3	3.8	4.4
Bipolar Disorder (2018)	9.5	15.0	24.1	4.4	4.5	1.9	4.6	3.5	4.0	-4.3	-4.6	4.3	1.5	3.4	4.4	2.7	2.3	3.6	2.5	4.7	4.4	4.9	4.1	3.9	4.4	2.0	4.2	4.1	4.3
Trunk fat percentage	9.0	36.0	66.6	-7.7	-3.7	-6.2	-6.7	-4.8	-8.2	6.9	5.3	-3.7	-5.2	-0.8	-6.5	-5.7	-6.6	-5.4	-8.1	-6.3	-5.3	-6.1	-5.4	-6.6	-4.6	-7.5	-5.8	-5.2	-6.5
Trunk fat mass	8.4	36.0	64.2	-7.8	-3.8	-6.2	-6.7	-4.9	-8.0	6.6	5.3	-3.9	-5.0	-1.1	-6.5	-5.5	-7.0	-5.2	-8.0	-6.3	-5.4	-6.1	-5.5	-6.4	-4.6	-7.7	-6.0	-5.5	-6.5
Bipolar Disorder (2011)	7.8	7.5	12.0	3.1	2.5	2.7	3.4	3.5	3.2	-3.2	-3.0	2.5	2.1	1.2	3.3	3.1	1.2	3.0	2.7	3.5	2.9	3.2	2.6	3.2	3.1	1.1	2.1	1.5	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	7.3	23.2	46.9	-5.8	-3.5	-3.5	-5.4	-5.2	-6.8	5.8	4.8	-3.1	-6.1	-0.9	-4.6	-4.0	-4.4	-6.0	-5.9	-5.4	-4.2	-5.0	-3.7	-4.4	-3.9	-4.8	-4.8	-4.7	-4.7
Forced expiratory volume in 1-second (FEV1)	6.5	22.0	46.8	-5.7	-3.4	-2.9	-5.5	-5.2	-6.8	5.7	4.9	-2.9	-5.6	-0.5	-4.6	-4.1	-4.1	-5.5	-6.0	-5.4	-4.0	-4.9	-3.5	-4.3	-3.8	-4.7	-4.7	-4.3	-4.3
Sitting height	6.0	42.7	68.2	-7.7	-5.8	-6.5	-7.1	-6.7	-8.3	7.0	6.1	-5.7	-7.2	-3.6	-7.0	-5.3	-6.0	-7.1	-6.3	-7.1	-6.5	-6.9	-6.3	-6.7	-6.0	-7.8	-5.4	-6.0	-5.9
Number of full sisters	5.8	7.0	13.9	2.8	3.1	3.0	2.7	2.7	2.7	-3.0	-3.0	2.8	1.6	2.2	2.4	3.7	2.0	2.8	2.3	2.8	2.9	2.8	3.0	2.8	2.8	2.0	2.4	1.9	1.8
Body fat percentage	5.6	22.3	47.3	-6.2	-2.4	-5.2	-5.2	-3.4	-6.5	5.2	3.9	-2.5	-4.0	0.0	-5.0	-4.4	-5.8	-4.0	-6.9	-4.9	-4.0	-4.6	-4.1	-5.1	-3.2	-6.5	-4.7	-4.1	-5.0
Lung FEV1/FVC ratio	5.5	27.9	69.2	-6.8	-3.6	-1.8	-5.3	-4.3	-7.2	5.2	4.5	-3.4	-2.2	-1.6	-5.4	-4.8	-8.2	-4.0	-6.6	-5.0	-4.5	-5.3	-4.9	-4.7	-3.8	-8.3	-5.8	-6.2	-6.7
Whole body fat mass	5.3	22.3	44.3	-6.2	-2.7	-5.2	-5.2	-3.5	-6.2	5.0	3.9	-2.9	-3.5	-0.7	-5.1	-4.1	-6.2	-3.8	-6.5	-4.9	-4.1	-4.7	-4.4	-5.0	-3.4	-6.7	-4.8	-4.5	-5.1
Forced vital capacity (FVC), Best measure	4.4	16.0	37.2	-4.7	-3.1	-3.1	-4.8	-4.3	-5.9	5.2	4.4	-2.5	-6.1	-0.4	-3.8	-3.7	-2.3	-5.6	-4.4	-4.7	-3.5	-4.2	-2.7	-3.7	-3.3	-3.0	-3.3	-3.1	-3.3
Had menopause	4.3	5.4	13.0	2.3	3.3	2.0	2.5	1.2	1.9	-2.0	-2.5	3.4	-0.3	3.4	2.2	1.6	0.9	1.3	0.7	2.9	3.1	2.7	2.9	2.4	3.6	0.8	2.2	2.0	1.2
Number of children fathered	4.3	4.9	8.4	2.6	2.1	2.3	2.2	1.5	2.3	-1.7	-2.0	2.3	1.7	1.9	2.5	2.0	2.2	2.1	2.9	2.3	2.4	2.3	2.5	2.1	2.4	1.6	2.2	2.5	2.1
Worry too long after embarrassment	4.2	7.0	10.2	-3.0	-2.3	-2.7	-2.9	-3.0	-3.0	2.9	2.3	-2.6	-1.5	-1.8	-3.2	-2.0	-2.4	-2.5	-2.8	-3.0	-2.8	-2.8	-2.8	-3.1	-3.2	-2.9	-2.6	-2.1	-2.0
Illnesses of mother	4.1	5.1	7.3	-2.4	-2.7	-2.3	-2.5	-1.9	-2.0	2.7	2.7	-2.6	-1.4	-2.3	-2.7	-1.9	-0.7	-2.4	-1.0	-2.6	-2.6	-2.5	-2.5	-2.7	-2.5	-0.4	-2.2	-2.0	-2.1
Mean Putamen Volume	3.9	4.4	8.2	2.2	2.7	1.6	2.6	0.6	2.6	-2.4	-2.5	2.8	0.4	2.4	2.0	0.9	0.1	2.3	0.2	2.6	2.8	2.5	2.3	2.4	2.9	1.0	1.9	1.7	1.8
Pulse wave Arterial Stiffness index	3.9	4.6	8.3	-2.4	-2.1	-2.3	-2.1	-1.1	-1.9	1.5	1.7	-2.3	-1.6	-2.3	-2.2	-1.5	-2.3	-1.9	-2.2	-2.1	-2.2	-2.3	-2.4	-2.0	-2.0	-2.6	-2.4	-2.9	-2.5
Hypothyroidism (self reported)	3.5	8.1	14.7	-3.2	-3.0	-2.6	-3.0	-2.0	-3.2	3.0	2.8	-3.0	-1.5	-2.4	-3.2	-1.6	-2.6	-2.8	-1.5	-2.9	-3.2	-3.3	-3.2	-3.3	-2.8	-3.6	-2.4	-2.4	-3.8
Forced vital capacity (FVC)	3.5	13.6	31.6	-4.4	-2.8	-2.5	-4.6	-4.1	-5.6	4.8	4.2	-2.2	-5.2	0.0	-3.6	-3.4	-2.1	-4.8	-4.2	-4.5	-3.2	-4.0	-2.4	-3.5	-3.1	-2.8	-3.0	-2.8	-2.8
Weight	3.5	17.0	35.3	-5.4	-2.7	-4.2	-4.4	-3.5	-5.1	4.0	3.5	-2.7	-2.8	-1.0	-4.5	-3.3	-5.9	-2.9	-5.4	-4.3	-3.6	-4.1	-4.0	-3.9	-3.1	-5.8	-4.5	-4.5	-4.3
Hearing difficulty/problems: Yes	3.4	5.1	15.4	1.6	3.2	1.9	1.7	1.8	1.8	-1.9	-2.1	3.2	2.4	3.9	1.5	1.6	0.8	2.9	0.7	2.0	2.7	2.4	2.6	2.0	2.8	1.3	2.2	2.3	2.5
Hip circumference	3.4	14.7	37.2	-4.9	-1.4	-4.5	-3.7	-3.5	-4.7	3.6	2.3	-2.0	-2.5	-0.2	-4.1	-2.7	-6.0	-2.6	-6.1	-3.6	-2.9	-3.5	-3.6	-3.6	-2.5	-6.1	-4.4	-3.9	-4.0
Hypothyroidism/myxoedema (self-reported)	3.4	6.6	12.9	-2.9	-2.5	-2.1	-2.7	-2.2	-3.0	2.9	2.6	-2.7	-2.0	-2.1	-2.9	-1.7	-2.0	-2.7	-1.1	-2.7	-2.9	-3.1	-2.7	-3.1	-2.6	-2.7	-2.1	-2.2	-3.6
Irritability	3.4	5.7	8.8	-2.6	-2.6	-2.2	-2.6	-1.6	-2.3	2.4	2.4	-2.8	-0.6	-2.6	-2.7	-2.1	-1.2	-2.3	-1.4	-2.6	-2.8	-2.9	-2.8	-2.7	-2.8	-1.8	-2.2	-2.5	-3.0
Qualifications: nursing, teaching	3.3	5.2	10.2	-2.6	-1.8	-2.1	-2.8	-2.2	-3.1	3.2	2.6	-2.1	-1.8	-0.9	-2.8	-2.9	-0.4	-2.6	-1.6	-2.8	-2.5	-2.7	-2.1	-2.9	-2.2	-1.1	-1.3	-1.3	-1.9
Age at first live birth	3.0	5.4	10.8	-2.4	-2.3	-2.1	-2.5	-2.3	-2.7	2.8	2.2	-2.5	-2.8	-2.0	-2.5	-2.0	-0.9	-3.3	-2.0	-2.4	-2.6	-2.5	-2.5	-2.6	-2.2	-1.6	-1.5	-1.6	-2.3
Blood Eosinophil Count	2.9	22.3	39.4	4.8	5.3	5.0	4.2	1.8	4.0	-4.5	-4.2	6.0	2.6	6.3	3.8	3.5	4.5	4.1	3.5	4.6	5.4	5.0	5.7	4.3	5.6	3.6	5.9	6.2	5.1
Age when periods started (menarche)	2.9	7.0	12.7	2.6	3.1	2.2	2.3	1.8	2.1	-2.2	-2.4	3.2	1.2	3.3	2.6	2.2	2.5	2.3	2.9	2.6	2.9	2.7	3.2	2.4	2.7	2.1	3.4	3.6	2.9
Chronic bronchitis/emphysema (father)	2.9	3.4	5.6	2.2	1.5	0.5	2.0	2.2	2.4	-2.0	-2.0	1.6	0.7	0.8	2.0	2.3	1.6	1.3	2.2	2.1	1.8	2.0	1.8	1.6	2.0	1.2	2.2	1.8	1.9
Number of live births	2.9	4.1	7.7	2.2	1.9	1.8	1.8	1.7	1.8	-1.3	-1.6	2.2	1.0	2.0	2.0	1.7	2.6	1.6	2.8	2.0	2.0	2.0	2.3	1.6	2.3	2.1	2.8	2.5	2.3
Qualifications: O levels/GCSEs or equivalent	2.9	4.6	11.5	-1.8	-2.9	-1.3	-1.6	-2.0	-1.2	1.4	2.3	-2.9	-0.9	-3.4	-1.9	-2.0	-1.7	-1.5	-1.8	-1.9	-2.4	-2.2	-2.8	-1.8	-2.9	-1.1	-2.6	-2.7	-2.6
Medication: Ventolin 100micrograms inhaler	2.9	3.7	10.4	1.7	1.8	1.4	1.8	2.5	1.9	-1.9	-1.7	1.7	3.2	1.3	1.6	2.5	1.1	2.9	2.4	1.9	1.8	1.8	1.6	2.0	1.7	1.8	1.6	1.4	1.8
Number of full brothers	2.9	3.7	7.6	2.3	1.8	1.6	2.2	1.9	2.3	-2.6	-2.1	1.8	0.3	1.3	2.8	1.4	1.1	1.9	0.9	1.9	2.0	2.2	2.1	2.2	1.9	1.7	1.6	2.0	2.1
Relative age of first facial hair	2.8	5.8	11.3	-2.9	-2.1	-3.4	-2.6	-2.0	-2.6	2.4	2.5	-2.1	-2.2	-1.4	-2.9	-1.7	-2.4	-2.5	-1.6	-2.6	-2.5	-2.6	-2.6	-2.4	-2.5	-2.3	-2.3	-2.6	-2.4
Number of incorrect matches in round	2.8	4.7	7.9	2.3	2.3	1.9	2.0	1.7	2.1	-2.8	-2.0	2.2	2.4	1.9	1.7	1.7	2.3	2.5	1.9	2.0	2.1	2.3	2.2	2.1	2.2	2.2	2.2	2.3	2.5
Leg fat mass (right)	2.8	11.0	30.7	-4.5	-1.4	-3.8	-3.5	-2.1	-4.4	3.2	2.3	-1.6	-2.1	0.1	-3.3	-2.3	-5.3	-2.1	-5.2	-3.3	-2.6	-3.1	-3.0	-3.2	-1.9	-5.5	-3.6	-3.3	-3.5
Average weekly champagne plus white wine intake	2.8	3.8	8.7	-1.6	-1.9	-1.7	-1.6	-2.7	-1.9	2.1	1.7	-2.0	-2.5	-1.7	-1.8	-3.0	-1.2	-2.6	-1.6	-1.7	-1.9	-1.8	-2.0	-2.2	-1.9	-1.5	-1.4	-1.2	-2.0
Waist Hip Ratio (WHR)	2.7	12.2	26.3	-4.6	-4.5	-1.1	-5.0	-0.7	-5.1	4.7	5.1	-3.5	-1.8	-1.9	-3.6	-2.2	-1.4	-3.8	-1.7	-4.5	-4.0	-4.4	-3.0	-3.3	-3.6	-1.6	-2.4	-3.2	-3.5
Qualifications: A levels/AS levels or equivalent	2.7	5.9	8.7	-2.5	-2.4	-2.5	-2.2	-2.3	-2.3	2.7	2.2	-2.8	-1.5	-2.7	-2.6	-1.8	-2.0	-2.4	-2.0	-2.4	-2.6	-2.5	-3.0	-2.7	-2.9	-1.8	-2.7	-2.5	-2.7
Unable to work because of sickness or disability	2.7	3.5	9.0	1.7	1.7	1.9	1.2	1.3	1.1	-0.5	-0.8	2.4	0.2	3.0	2.1	0.1	2.4	0.5	0.9	1.2	2.0	1.9	2.6	1.3	2.1	2.3	2.5	2.9	2.8
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	4.0	6.5	1.9	1.7	1.8	1.5	1.9	2.0	-2.0	-1.4	2.3	1.4	2.3	1.8	2.0	2.1	1.8	2.1	1.7	2.1	2.0	2.4	1.9	2.0	2.0	2.5	2.1	2.4
Leg fat percentage (right)	2.6	9.5	28.1	-4.3	-0.8	-3.8	-3.3	-1.3	-4.5	3.1	2.0	-1.0	-2.3	1.0	-2.9	-2.3	-4.5	-2.0	-5.2	-3.0	-2.2	-2.7	-2.4	-3.1	-1.5	-5.3	-3.1	-2.6	-3.2
Pulse rate, automated reading	2.6	8.3	14.4	3.3	3.0	2.0	3.6	3.5	3.8	-3.3	-3.5	2.6	2.2	1.4	3.5	2.6	1.1	3.2	2.2	3.8	3.0	3.5	2.5	3.1	3.0	1.8	2.7	2.3	2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.5	2.9	5.9	1.9	1.5	2.3	1.6	1.1	1.8	-1.2	-1.2	1.9	1.1	1.9	2.0	0.6	1.8	1.6	0.3	1.4	1.8	1.8	2.2	1.6	1.8	2.4	1.5	2.1	1.9
Leg fat mass (left)	2.5	9.6	26.8	-4.3	-1.3	-3.5	-3.2	-1.9	-4.0	2.9	2.1	-1.5	-1.9	0.1	-3.1	-2.4	-5.2	-1.8	-5.0	-3.0	-2.4	-2.8	-2.8	-2.9	-1.8	-5.2	-3.3	-3.1	-3.2
Type 2 Diabetes (T2D) (2018)	2.4	4.6	8.8	-2.5	-1.9	-1.8	-2.8	-2.6	-3.0	2.4	2.5	-1.8	-2.0	-0.9	-2.9	-2.3	-0.6	-1.9	-1.3	-2.7	-2.3	-2.6	-1.8	-2.5	-2.1	-1.4	-1.4	-1.4	-1.6
Mouth/teeth dental problems: Dentures	2.4	4.1	7.8	2.4	2.0	1.7	2.4	1.8	2.6	-1.9	-2.3	1.8	2.0	0.8	1.9	1.5	1.3	2.0	2.8	2.4	2.2	2.3	2.0	1.8	2.0	1.6	1.9	2.0	1.9
Diastolic blood pressure, automated reading	2.4	7.3	17.6	-2.5	-3.0	-3.6	-1.9	-1.4	-1.9	1.8	1.6	-3.2	-1.8	-3.7	-2.2	-2.1	-3.5	-2.5	-1.7	-2.1	-2.9	-2.5	-3.5	-2.7	-2.6	-4.2	-2.8	-2.9	-3.0
Medication: Co-codamol	2.3	2.7	4.2	-1.8	-1.6	-1.7	-1.6	-1.4	-1.3	1.6	1.4	-1.8	0.1	-1.7	-2.0	-1.8	-1.8	-1.4	-1.4	-1.7	-1.8	-1.8	-2.1	-1.8	-2.0	-1.6	-1.6	-1.5	-1.1
Fed-up feelings	2.3	4.2	6.2	-2.3	-2.3	-2.0	-2.2	-1.4	-2.0	1.8	2.2	-2.1	-1.3	-1.7	-1.9	-2.1	-2.4	-1.5	-2.0	-2.3	-2.1	-2.3	-2.2	-2.1	-2.3	-2.5	-1.9	-1.7	-1.5
Fluid intelligence score	2.3	4.7	10.6	-2.4	-2.1	-2.8	-2.2	-1.6	-2.4	2.4	1.8	-2.0	-1.8	-1.5	-2.3	-1.5	-2.1	-2.9	-2.3	-2.2	-2.2	-2.2	-2.3	-2.6	-1.8	-3.3	-1.6	-1.5	-1.8
Chronic bronchitis/emphysema (mother)	2.3	2.7	5.5	1.9	1.0	2.3	1.4	1.3	1.5	-1.7	-0.8	1.4	1.3	1.2	1.6	0.7	2.3	2.2	1.6	1.6	1.4	1.5	1.8	1.6	1.3	2.0	2.1	2.1	1.6
Commuting to job workplace: Walk	2.3	2.4	5.8	1.9	1.7	0.7	2.4	1.2	2.3	-2.0	-2.2	1.6	-0.3	0.6	1.9	1.1	-0.3	1.6	1.1	2.3	1.9	2.1	1.4	1.9	1.7	0.3	0.8	0.4	0.4
Supplements: Glucosamine	2.2	2.8	4.6	-1.8	-1.7	-1.8	-1.9	-2.1	-1.7	2.1	2.0	-1.6	-1.9	-0.9	-2.0	-1.6	-0.7	-1.8	-1.0	-2.0	-1.7	-2.0	-1.6	-1.9	-1.9	-0.5	-1.4	-1.3	-1.5
Waist circumference	2.2	8.1	22.1	-4.1	-1.5	-2.8	-3.2	-1.2	-3.8	3.0	2.2	-1.6	-0.6	-0.1	-3.1	-1.5	-4.7	-1.6	-4.0	-3.0	-2.4	-2.8	-2.7	-2.6	-2.0	-4.4	-3.3	-3.1	-2.9
Hair/balding pattern: Pattern 3	2.2	3.2	6.9	2.3	1.3	1.5	2.1	1.7	2.3	-2.0	-1.9	1.0	0.8	0.0	2.2	2.6	1.7	1.9	2.6	2.1	1.6	1.8	1.6	2.1	1.4	1.8	1.5	1.0	1.5
Emphysema/chronic bronchitis	2.2	2.4	5.0	1.5	1.5	1.1	1.2	2.2	1.3	-1.2	-1.1	1.6	1.6	1.3	1.4	1.0	1.8	1.6	2.2	1.4	1.4	1.6	1.7	1.2	1.4	1.8	1.8	1.6	2.0
Gout (self-reported)	2.1	2.8	4.4	-1.8	-1.9	-0.8	-1.7	-1.5	-1.7	1.5	2.0	-1.9	-1.2	-1.6	-1.5	-1.9	-1.4	-1.3	-2.1	-1.8	-1.9	-1.8	-1.8	-1.4	-2.0	-0.7	-2.0	-1.6	-1.9
Wheeze or whistling in the chest in last year	2.1	3.8	7.4	1.5	2.4	0.8	1.5	2.7	1.9	-1.9	-1.8	2.2	2.7	2.4	1.3	2.7	0.9	2.4	1.5	1.7	2.0	2.0	2.0	1.8	2.3	1.6	1.5	1.5	2.1
Alcohol intake frequency.	2.1	4.9	13.2	1.8	2.1	2.2	1.9	3.6	2.0	-2.0	-1.7	2.3	3.3	2.1	2.7	2.1	0.7	2.8	1.3	2.0	2.2	2.3	2.4	2.3	2.1	1.6	1.8	2.1	2.1
Blood Platelet Count	2.0	22.9	37.4	5.5	4.8	5.4	4.6	1.5	4.5	-4.2	-3.8	5.4	1.1	5.3	4.7	1.8	5.8	3.7	3.4	4.7	5.3	4.9	5.9	4.9	5.4	6.1	5.9	5.8	5.2
Heel T-Score	2.0	16.0	27.5	4.4	4.5	3.6	4.7	3.6	4.3	-4.6	-5.2	4.0	4.9	2.5	4.0	4.5	1.6	4.2	3.4	4.7	4.3	4.5	3.9	3.8	4.7	-0.2	3.3	3.4	3.6
Frequency of depressed mood in last 2 weeks	2.0	2.8	8.2	-1.8	-1.9	-1.4	-1.5	-1.4	-1.6	1.1	1.5	-1.5	-1.7	-1.6	-1.9	-2.1	-2.4	-1.3	-1.1	-1.4	-1.5	-1.8	-1.8	-1.4	-1.7	-2.9	-0.9	-1.8	-1.3
Diabetes (father)	2.0	2.5	9.6	-1.9	-1.0	-1.8	-1.8	-3.1	-2.1	1.5	1.4	-1.0	-1.7	-0.1	-2.3	-1.0	-1.5	-1.0	-1.0	-1.9	-1.4	-1.6	-1.4	-1.6	-1.4	-1.8	-1.1	-1.1	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	7.3	1.6	1.1	1.1	1.1	0.3	1.5	-1.4	-0.8	1.6	0.7	1.5	0.9	0.5	2.4	1.0	2.7	1.2	1.5	1.3	1.8	1.2	1.5	2.4	2.4	2.1	2.0
Leg fat percentage (left)	1.9	6.9	21.3	-3.7	-0.5	-3.3	-2.8	-1.1	-3.8	2.6	1.6	-0.6	-1.9	1.1	-2.5	-2.2	-4.2	-1.4	-4.5	-2.5	-1.8	-2.3	-2.0	-2.6	-1.2	-4.6	-2.4	-2.1	-2.5
Alzheimer’s Disease (including proxy)	1.8	2.6	7.6	2.0	1.4	1.9	1.9	1.1	2.0	-2.1	-1.8	1.2	2.8	0.4	1.4	1.5	1.3	2.4	0.9	1.9	1.6	1.5	1.5	1.6	1.6	0.8	0.9	1.0	1.2
Allergy or Eczema	1.8	4.8	8.8	2.8	2.4	2.3	2.8	1.1	2.9	-2.3	-2.5	2.3	1.1	1.5	2.5	3.0	1.7	1.8	1.2	2.8	2.5	2.5	2.2	2.3	2.5	1.8	1.4	1.8	0.8
Allergy	1.8	4.2	9.2	-2.4	-2.0	-2.1	-2.1	-1.5	-2.7	2.1	1.8	-1.8	-2.3	-1.2	-1.9	-2.0	-2.2	-2.4	-1.9	-2.1	-2.0	-2.0	-1.9	-1.9	-1.7	-3.0	-1.6	-1.9	-1.8
Blood clot in the leg (DVT)	1.8	2.4	8.3	1.0	0.9	2.3	0.5	1.6	0.8	-0.5	-0.0	1.5	1.0	2.0	1.0	-0.0	2.0	1.2	1.7	0.8	1.2	1.1	1.9	1.2	1.4	2.7	2.9	2.1	2.0
Family relationship satisfaction	1.8	2.2	5.6	1.3	1.9	1.1	1.2	1.0	1.2	-0.9	-1.4	2.2	0.3	2.4	1.1	1.1	1.3	0.9	0.9	1.5	1.9	1.6	2.0	1.1	2.0	1.1	1.6	1.6	1.5
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	5.1	-1.9	-1.2	-1.7	-1.6	-1.3	-1.6	1.7	1.6	-1.2	-0.2	-0.6	-1.4	-2.3	-1.5	-1.1	-2.1	-1.6	-1.4	-1.6	-1.5	-1.4	-1.2	-0.6	-1.8	-1.5	-1.6
Verbal and Numeric Reasoning (VNR)	1.7	4.2	9.6	-2.2	-1.6	-2.7	-1.9	-1.4	-2.1	2.6	1.7	-1.6	-1.8	-1.0	-2.0	-2.3	-2.0	-3.0	-3.1	-2.0	-1.9	-1.8	-2.1	-2.4	-1.4	-2.4	-1.5	-1.5	-1.5
Multivitamins +/- minerals	1.7	2.1	6.1	1.6	1.1	1.2	1.3	2.1	1.2	-1.3	-1.0	1.2	0.8	0.8	1.4	1.8	1.7	1.4	2.5	1.5	1.3	1.4	1.6	1.4	1.4	1.2	1.8	1.3	1.5
Hearing difficulty/problems with background noise	1.7	2.7	5.1	1.4	1.9	1.0	1.4	2.0	1.5	-1.3	-1.5	2.2	0.8	2.3	1.6	1.2	1.0	1.6	1.5	1.7	1.9	1.9	1.9	1.4	1.8	1.0	2.2	1.8	1.7
Falls in the last year	1.7	2.3	4.3	-1.4	-1.9	-1.1	-1.8	-1.7	-2.0	1.6	1.9	-1.7	-2.1	-1.2	-1.2	-1.9	-0.1	-1.3	-1.3	-2.0	-1.7	-1.8	-1.2	-1.4	-1.9	-0.2	-1.1	-0.9	-0.7
Illnesses of father: High blood pressure	1.7	2.1	5.0	-1.6	-1.4	-1.6	-1.6	-1.8	-1.7	1.7	1.0	-1.4	-0.7	-1.0	-1.7	-0.5	-1.2	-1.8	-1.1	-1.7	-1.5	-1.5	-1.6	-1.8	-1.5	-2.2	-1.3	-0.6	-0.9
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	8.6	0.9	0.9	2.2	0.4	1.4	0.8	-0.5	0.1	1.5	0.8	2.1	1.0	-0.2	1.9	1.0	1.4	0.7	1.1	1.0	1.8	1.2	1.4	2.9	2.7	1.9	1.9
Cardiovascular Disease	1.6	5.4	15.9	-2.7	-2.2	-2.2	-1.9	-1.5	-2.1	1.7	1.7	-2.3	0.4	-2.3	-2.5	-1.7	-4.0	-1.3	-2.5	-2.1	-2.3	-2.1	-2.9	-2.0	-2.2	-3.5	-2.7	-3.0	-2.2
Comparative body size at age 10	1.6	4.3	12.4	2.2	1.4	1.1	1.6	1.7	2.3	-2.2	-1.5	1.4	3.5	1.2	1.9	0.1	2.7	2.5	2.2	1.4	1.6	1.7	1.8	1.7	1.5	2.5	2.4	3.0	3.2
Asthma (self-reported)	1.6	3.1	6.5	1.8	1.9	0.4	1.6	2.1	2.4	-1.7	-1.7	1.5	2.5	1.2	1.6	2.2	1.6	1.9	1.2	1.6	1.6	1.8	1.5	1.6	1.4	2.5	1.4	1.5	2.0
Arm fat mass (left)	1.6	6.5	20.4	-3.5	-1.1	-3.3	-2.5	-1.4	-3.0	2.3	1.6	-1.3	-0.6	-0.2	-2.6	-1.7	-4.5	-1.2	-3.6	-2.5	-2.0	-2.3	-2.5	-2.5	-1.5	-4.5	-3.0	-2.6	-2.6
Ever depressed for a whole week	1.6	2.0	3.2	1.4	1.6	1.7	1.3	0.9	1.4	-1.3	-1.2	1.7	1.3	1.8	1.1	1.5	1.1	1.8	1.0	1.4	1.6	1.5	1.6	1.3	1.7	1.4	1.2	1.3	1.1
Major Depression (MDD)	1.5	1.8	3.9	1.0	1.1	1.4	0.7	1.8	0.8	-0.7	-0.7	1.7	0.1	1.9	1.3	0.9	1.6	0.9	1.4	1.0	1.4	1.2	1.8	1.1	1.7	1.3	1.8	1.3	2.0
Ever used hormone-replacement therapy (HRT)	1.5	1.9	3.8	1.5	1.4	1.0	1.3	1.1	1.3	-1.5	-1.5	1.3	1.7	0.9	0.9	1.9	1.6	1.7	1.4	1.4	1.4	1.3	1.4	1.1	1.8	0.6	1.5	1.3	1.1
Pack years adult smoking proportion	1.5	2.3	4.1	-1.9	-1.7	-1.6	-1.8	0.0	-1.9	1.5	1.5	-1.6	-0.2	-1.3	-1.6	-0.5	-1.3	-1.2	-0.5	-1.7	-1.7	-1.8	-1.7	-1.7	-1.4	-2.0	-1.4	-1.8	-1.4
Asthma	1.5	3.0	7.4	1.6	1.8	0.4	1.5	2.4	2.3	-1.7	-1.6	1.3	2.7	1.1	1.5	2.3	1.6	2.0	1.5	1.5	1.5	1.7	1.4	1.6	1.3	2.5	1.4	1.4	2.0
Basal metabolic rate	1.5	8.4	22.4	-3.7	-2.2	-2.7	-2.9	-2.6	-3.0	2.3	2.5	-2.3	-1.1	-1.6	-3.3	-1.9	-4.7	-1.7	-3.4	-3.0	-2.6	-2.9	-3.0	-2.4	-2.3	-4.0	-3.6	-3.8	-3.0
Pack years of smoking	1.5	2.2	4.0	-1.9	-1.6	-1.7	-1.9	-0.2	-1.9	1.6	1.5	-1.4	-0.4	-1.1	-1.7	-0.9	-1.1	-1.3	-0.4	-1.7	-1.7	-1.8	-1.6	-1.8	-1.3	-2.0	-1.1	-1.5	-1.2
Alzheimer’s Disease (in father)	1.4	1.5	3.2	1.4	1.4	1.8	1.4	0.5	1.3	-1.5	-1.5	1.3	0.8	1.0	1.4	1.4	0.6	1.6	0.2	1.4	1.4	1.3	1.3	1.6	1.6	0.9	0.7	0.6	0.9
HDL Cholesterol	1.4	2.3	6.1	1.7	1.3	1.4	1.3	0.9	1.5	-0.7	-1.1	1.4	1.1	1.4	1.5	0.6	1.9	0.7	1.9	1.3	1.4	1.4	1.6	1.4	1.4	2.5	2.3	2.1	1.9
Chronotype (morning person)	1.4	3.3	10.7	-1.4	-1.9	-1.8	-1.3	-3.3	-1.5	1.4	1.0	-1.8	-1.9	-2.0	-1.8	-2.0	-1.8	-1.6	-0.2	-1.6	-1.6	-1.8	-1.9	-2.1	-2.1	-3.2	-1.1	-0.8	-1.3
Tense / ‘highly strung’	1.4	2.3	3.8	1.9	1.6	1.8	1.8	1.0	1.9	-1.9	-1.4	1.6	1.7	1.2	1.6	0.9	1.4	1.5	1.2	1.9	1.6	1.8	1.4	1.4	1.6	1.7	0.7	1.3	0.9
Medication: Allopurinol	1.4	1.9	4.6	-1.5	-1.7	0.4	-1.6	-1.0	-1.4	1.3	2.2	-1.4	-0.3	-1.0	-1.4	-1.7	-0.9	-0.8	-1.4	-1.5	-1.5	-1.5	-1.3	-1.0	-1.7	0.5	-1.4	-1.5	-1.8
Hand grip strength (left)	1.3	3.4	12.1	1.3	2.1	2.5	0.8	0.8	0.9	-0.7	-0.7	2.7	0.6	3.5	1.3	1.4	2.3	0.8	0.2	1.1	2.1	1.6	2.7	1.7	2.3	3.4	1.5	1.6	1.7
Mouth/teeth dental problems	1.3	2.1	5.1	-1.5	-1.0	-1.0	-1.7	-1.9	-1.7	1.7	1.7	-1.0	-1.7	-0.2	-1.7	-0.8	0.2	-2.2	-2.3	-1.5	-1.4	-1.7	-1.2	-1.3	-1.2	0.1	-1.2	-1.1	-1.4
Arm fat mass (right)	1.3	5.4	18.9	-3.2	-0.9	-3.0	-2.2	-1.2	-2.7	1.9	1.3	-1.1	-0.5	-0.0	-2.3	-1.6	-4.3	-1.0	-3.4	-2.2	-1.7	-2.0	-2.2	-2.2	-1.2	-4.3	-2.8	-2.4	-2.3
Breastfed as a baby	1.3	1.6	3.6	1.4	1.9	1.4	1.4	-0.6	1.2	-1.1	-1.4	1.6	0.1	1.6	0.6	0.1	0.8	1.0	0.2	1.6	1.5	1.3	1.4	1.2	1.3	1.4	1.8	1.5	0.7
Peak expiratory flow (PEF)	1.3	3.0	8.1	-1.9	-1.3	-0.5	-1.9	-2.9	-2.4	2.1	1.7	-1.4	-1.3	-0.6	-1.8	-1.3	-1.4	-1.7	-1.8	-2.1	-1.6	-1.8	-1.5	-1.6	-1.8	-1.7	-2.2	-1.4	-1.3
Pulse wave peak to peak time	1.3	1.5	3.9	1.3	1.2	1.5	1.1	0.1	0.8	-0.5	-0.9	1.5	0.6	1.8	1.2	0.8	1.5	0.9	1.1	1.2	1.3	1.2	1.5	1.0	1.1	1.6	1.4	2.0	1.3
Arm fat percentage (left)	1.3	5.1	14.3	-3.1	-0.7	-3.1	-2.3	-0.9	-2.8	2.2	1.4	-0.9	-0.8	0.2	-2.3	-1.8	-3.8	-1.2	-3.5	-2.2	-1.7	-2.0	-2.1	-2.4	-1.2	-3.8	-2.6	-2.1	-2.3
Crohns Disease (2017)	1.2	2.7	8.8	1.4	1.5	1.3	0.8	1.0	0.9	-1.4	-0.7	1.7	0.6	2.2	1.2	0.6	3.0	1.1	1.7	0.9	1.4	1.3	1.9	1.3	1.4	2.9	2.2	2.8	2.0
Blood Red Count	1.2	11.4	18.7	-3.8	-3.9	-2.2	-4.0	-3.1	-4.3	3.9	4.1	-3.4	-3.3	-2.4	-3.3	-3.1	-1.8	-3.5	-2.0	-3.9	-3.8	-4.0	-3.3	-3.7	-3.9	-2.8	-2.4	-2.5	-3.7
Respiratory disease	1.2	2.7	8.0	1.7	1.6	0.3	1.5	1.7	2.2	-1.6	-1.4	1.2	2.2	0.9	1.5	2.1	2.2	1.6	1.3	1.4	1.4	1.6	1.4	1.5	1.1	2.8	1.5	1.6	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.5	4.1	-1.4	-1.4	-1.3	-1.2	-0.3	-1.3	1.4	1.2	-1.3	-1.6	-1.1	-0.9	-1.1	-1.4	-1.3	-1.0	-1.1	-1.3	-1.2	-1.2	-1.3	-1.1	-2.0	-0.7	-1.2	-0.9
Neck or shoulder pain in last month	1.2	1.7	3.1	1.1	1.5	1.0	1.2	1.1	1.1	-1.0	-1.2	1.8	0.4	1.7	1.3	0.5	0.4	1.1	1.0	1.3	1.6	1.6	1.6	1.4	1.5	0.7	1.7	1.2	1.7
Mean time to correctly identify matches	1.2	2.2	4.7	1.6	1.7	0.4	1.4	1.2	1.3	-0.9	-1.4	1.8	-0.5	1.6	1.5	0.7	2.0	0.3	1.6	1.5	1.6	1.7	1.8	1.0	1.9	1.7	2.0	1.6	2.2
Average weekly red wine intake	1.2	1.7	4.9	-1.7	-0.8	-2.2	-1.3	-1.4	-1.3	1.3	1.0	-0.6	0.2	-0.1	-2.0	-1.4	-1.6	-1.3	-1.4	-1.2	-1.0	-1.2	-1.4	-1.5	-0.8	-1.9	-1.1	-1.1	-1.1
Age started oral contraceptive pill	1.2	1.5	3.3	1.6	1.3	0.4	1.6	-0.5	1.0	-1.1	-1.4	1.2	-1.4	0.7	1.2	-0.7	1.5	0.5	1.2	1.8	1.3	1.3	1.1	0.9	1.5	0.6	1.8	1.6	0.9
Vitamin and mineral supplements	1.1	1.4	5.0	-1.6	-0.8	-0.7	-1.3	-1.4	-1.0	0.9	0.8	-0.9	0.2	-0.4	-1.4	-0.6	-1.8	-0.7	-2.2	-1.4	-1.0	-1.2	-1.3	-1.0	-1.1	-1.1	-1.8	-1.2	-1.3
Medication: Levothyroxine sodium	1.1	1.9	4.2	-1.4	-1.5	-0.7	-1.4	-0.9	-1.5	1.5	1.3	-1.7	-0.6	-1.5	-1.4	-0.5	-1.1	-1.4	-0.0	-1.4	-1.7	-1.7	-1.6	-1.6	-1.5	-1.6	-1.2	-1.1	-2.0
Time employed in main current job	1.1	1.3	3.9	1.4	0.8	1.5	1.2	1.2	1.2	-0.7	-1.2	0.7	1.0	0.4	1.6	2.0	1.4	0.9	1.3	1.0	0.9	1.2	1.1	1.0	0.8	1.2	0.8	1.3	0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.6	1.4	1.4	0.9	1.3	-0.8	1.1	-0.9	-1.2	1.6	0.4	1.4	0.7	-0.3	0.9	1.0	1.4	1.3	1.5	1.2	1.3	0.8	1.4	0.3	1.4	1.4	1.4
Migraine (self-reported)	1.1	1.4	3.8	0.5	1.4	1.3	0.5	1.4	0.6	-0.7	-0.6	1.3	1.9	1.9	1.0	0.6	0.6	1.3	-0.1	0.7	1.1	1.1	1.2	1.2	1.0	1.9	1.0	1.4	1.5
Arm predicted mass (right)	1.1	5.5	16.3	-3.1	-1.7	-2.0	-2.4	-2.3	-2.5	1.7	2.0	-1.7	-0.8	-1.1	-2.8	-1.4	-4.0	-1.1	-2.9	-2.4	-2.0	-2.4	-2.4	-1.7	-1.8	-3.4	-2.8	-3.0	-2.3
Commuting to job workplace: Car/motor vehicle	1.1	1.2	2.7	-1.3	-1.3	-1.4	-1.6	-0.0	-1.5	1.0	1.3	-1.6	-0.4	-1.1	-1.0	-0.2	0.2	-0.8	0.5	-1.6	-1.5	-1.5	-1.1	-1.2	-1.6	-0.0	-0.5	-0.5	0.1
Mineral and other dietary supplements	1.1	1.4	2.8	1.1	1.7	1.2	1.1	0.1	1.1	-1.6	-1.4	1.4	1.5	1.5	1.0	0.7	0.9	1.4	-0.6	1.0	1.3	1.3	1.2	1.2	1.5	0.8	0.6	1.3	1.4
Medication: Atorvastatin	1.1	1.4	2.7	1.1	1.1	1.5	0.9	1.4	1.0	-0.6	-0.8	1.3	1.3	1.4	1.1	0.9	1.3	0.6	0.9	1.2	1.2	1.2	1.4	1.1	1.4	1.6	1.2	1.1	1.4
Diabetes (mother)	1.0	1.3	2.7	1.0	1.0	1.6	1.1	0.7	1.1	-1.5	-1.1	1.1	0.6	1.0	1.5	1.3	-0.1	1.3	1.2	0.9	1.3	1.1	1.2	1.6	1.0	0.2	0.9	1.1	1.5
High blood pressure (mother)	1.0	1.3	3.3	1.1	1.4	0.5	1.2	1.1	1.0	-1.5	-1.8	1.1	1.4	0.9	1.3	0.9	0.0	1.3	0.6	1.0	1.2	1.3	1.1	1.0	1.0	-0.7	1.0	1.2	1.7
Arm fat percentage (right)	1.0	4.0	13.5	-2.7	-0.5	-2.9	-2.0	-0.6	-2.5	1.8	1.0	-0.7	-0.6	0.3	-1.9	-1.5	-3.5	-0.9	-3.2	-1.8	-1.5	-1.6	-1.8	-2.2	-0.9	-3.7	-2.3	-1.8	-2.0
Trunk fat-free mass	1.0	5.5	15.2	-3.0	-1.9	-2.0	-2.3	-2.4	-2.4	1.7	2.0	-2.0	-0.9	-1.5	-2.8	-1.4	-3.9	-1.3	-2.6	-2.3	-2.1	-2.4	-2.5	-1.7	-1.8	-3.3	-2.9	-3.3	-2.3
Length of working week for main job	1.0	1.1	3.8	1.4	0.4	1.9	0.9	-0.8	1.3	-1.3	-0.6	0.6	0.6	0.1	0.7	0.7	1.5	1.0	1.0	0.8	0.8	0.7	1.1	1.0	0.8	1.8	1.0	1.1	0.8
Arm fat-free mass (right)	1.0	5.3	15.4	-3.1	-1.6	-1.9	-2.4	-2.4	-2.5	1.7	2.0	-1.6	-0.7	-0.9	-2.8	-1.5	-3.9	-1.1	-2.9	-2.4	-1.9	-2.4	-2.3	-1.7	-1.6	-3.3	-2.7	-2.9	-2.3
Mouth/teeth dental problems: Mouth ulcers	1.0	1.7	5.1	1.5	1.2	1.1	1.7	0.9	1.6	-2.0	-1.7	1.0	1.9	0.3	1.3	0.9	-0.2	2.3	1.0	1.5	1.3	1.6	0.9	1.4	1.0	-0.2	0.4	0.8	1.0
Alcohol drinker status: Never	1.0	1.2	3.4	1.1	0.6	1.6	0.8	1.5	1.0	-0.6	-0.4	0.8	1.2	0.8	1.7	0.2	1.2	0.7	0.7	0.7	0.8	1.0	1.1	0.9	0.4	1.8	1.3	1.8	1.2
Vascular/heart problems diagnosed by doctor	1.0	2.8	6.9	1.9	2.0	1.2	1.4	0.3	1.5	-1.0	-1.5	2.0	-0.5	2.1	1.6	1.9	2.6	0.7	1.8	1.5	1.9	1.6	2.3	1.4	1.4	2.0	1.6	2.1	1.6
Intelligence (Savage-Jansen 2018)	0.9	2.9	6.9	-1.8	-1.6	-1.7	-1.6	-0.5	-2.0	2.1	1.7	-1.5	-1.7	-1.2	-1.3	-1.7	-1.4	-2.5	-2.6	-1.5	-1.8	-1.5	-1.7	-1.9	-1.1	-1.8	-1.4	-1.6	-1.7
Irritable Bowel Disease (IBD)	0.9	2.1	10.3	1.1	1.0	1.0	0.3	0.3	0.6	-0.6	-0.3	1.3	-0.1	2.0	0.7	-0.5	3.2	0.3	1.0	0.5	1.0	0.8	1.7	0.6	0.8	2.9	2.5	3.1	1.9
Breast Cancer	0.9	2.2	4.9	-2.1	-0.7	-1.7	-1.7	-1.1	-1.8	1.3	1.3	-1.0	-0.4	-0.4	-2.1	-0.2	-1.7	-0.6	-1.6	-1.5	-1.4	-1.5	-1.6	-1.2	-1.3	-1.4	-2.2	-2.2	-1.6
Sensitivity / hurt feelings	0.9	1.6	3.7	1.3	1.5	0.7	1.2	0.4	0.9	-0.9	-1.6	1.5	-0.0	1.5	1.2	1.3	0.9	0.8	1.6	1.1	1.4	1.4	1.4	0.7	1.5	-0.1	1.8	1.9	1.9
Leg fat-free mass (left)	0.9	4.8	14.0	-2.7	-1.9	-2.1	-2.1	-1.9	-1.8	1.5	1.8	-1.9	-0.2	-1.7	-2.6	-1.2	-3.7	-0.9	-2.2	-2.2	-2.0	-2.1	-2.5	-1.7	-1.8	-3.0	-2.9	-3.1	-2.3
Average weekly fortified wine intake	0.9	1.0	3.7	-0.6	-0.6	-1.3	-0.5	-1.9	-0.6	0.7	0.3	-1.2	-1.4	-1.5	-1.3	-0.9	-0.7	-0.7	0.0	-0.6	-0.9	-1.2	-1.2	-1.0	-1.1	-1.0	-0.9	-1.1	-1.0
High blood pressure	0.9	2.6	10.4	-1.9	-1.4	-1.5	-1.1	-0.5	-1.3	0.8	1.0	-1.5	0.3	-1.7	-1.5	-1.4	-3.2	-0.7	-2.0	-1.3	-1.5	-1.3	-2.1	-1.3	-1.1	-2.6	-1.9	-2.2	-1.6
Medication: Atenolol	0.9	1.2	3.1	0.6	0.3	-0.1	1.3	1.6	1.4	-1.5	-1.3	0.1	1.8	-1.0	0.8	1.6	-1.7	1.5	-0.7	1.2	0.5	0.9	-0.2	1.2	0.7	-0.7	-0.8	-1.2	-0.1
Leg predicted mass (left)	0.9	4.7	14.2	-2.7	-1.8	-2.1	-2.0	-1.8	-1.8	1.4	1.8	-1.9	-0.2	-1.6	-2.5	-1.2	-3.8	-0.9	-2.3	-2.1	-2.0	-2.1	-2.4	-1.7	-1.7	-3.0	-2.9	-3.1	-2.3
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.3	1.2	1.0	1.2	1.3	0.2	1.5	-1.3	-1.2	1.0	0.7	0.7	1.0	0.4	0.3	1.2	0.1	1.3	1.2	1.3	1.0	1.1	1.2	1.1	0.8	1.0	1.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	2.3	-1.0	-0.6	-1.3	-0.7	-1.4	-0.8	0.9	0.5	-1.2	-0.1	-1.3	-1.1	-0.8	-1.4	-0.5	-1.0	-1.0	-1.0	-1.2	-1.5	-0.9	-1.5	-1.1	-1.1	-1.0	-1.2
Noisy workplace	0.9	1.2	2.3	1.0	1.3	1.4	0.9	1.5	0.8	-0.9	-0.8	1.3	0.7	1.3	1.1	1.4	1.1	1.3	0.3	1.2	1.1	1.1	1.1	1.0	1.2	0.9	0.7	1.0	0.6
Prospective memory result	0.9	1.1	2.7	1.2	0.4	1.6	1.0	0.4	1.3	-1.4	-0.7	0.4	1.6	-0.1	0.7	0.5	1.1	1.4	1.3	1.1	0.8	0.8	0.7	1.1	0.7	1.4	1.3	1.0	0.8
Trunk predicted mass	0.9	5.4	14.8	-2.9	-1.8	-2.0	-2.2	-2.4	-2.4	1.6	2.0	-1.9	-0.9	-1.5	-2.8	-1.4	-3.8	-1.3	-2.6	-2.3	-2.1	-2.3	-2.4	-1.7	-1.7	-3.3	-2.9	-3.2	-2.3
Ever highly irritable/argumentative for 2 days	0.9	1.1	3.1	-1.1	-1.6	-0.4	-1.0	-0.1	-0.9	0.6	1.1	-1.7	0.6	-1.8	-1.2	-0.5	-0.9	-0.4	0.4	-1.0	-1.4	-1.1	-1.4	-0.9	-1.5	-0.9	-0.2	-1.1	-0.7
Health satisfaction	0.9	1.2	3.5	0.5	1.1	1.3	0.6	1.6	0.7	-0.9	-0.7	1.2	1.6	1.4	0.8	0.4	-0.2	1.4	0.4	0.7	1.0	1.0	1.0	0.9	1.1	0.5	1.4	1.4	1.9
Shortness of breath walking on level ground	0.9	1.1	3.6	-1.4	-0.5	-0.7	-1.5	0.3	-1.5	1.6	1.7	-0.4	-0.0	0.6	-1.2	-1.7	-0.1	-0.8	-1.9	-1.3	-0.9	-0.9	-0.6	-1.2	-0.5	0.4	-0.9	-0.5	-0.6
Mouth/teeth dental problems: Loose teeth	0.9	1.0	4.1	1.0	0.4	1.2	0.8	2.0	0.4	-0.3	-0.5	0.7	0.9	0.5	1.3	0.2	1.0	0.6	1.9	1.0	0.7	0.9	1.0	0.8	0.9	0.8	1.7	0.9	1.0
Medication: Seretide 50 evohaler	0.9	1.0	2.9	1.0	0.9	0.2	0.7	1.2	0.8	-0.5	-0.9	0.9	0.9	0.9	0.9	1.2	1.7	0.8	1.4	0.9	1.0	0.8	1.0	0.5	1.2	0.9	1.3	1.4	1.3
Leg pain on walking	0.9	1.1	5.1	0.8	1.2	2.3	0.8	1.3	0.9	-0.7	-0.6	1.2	1.3	1.2	1.1	0.9	0.1	1.2	0.4	1.0	1.1	1.0	1.2	1.4	1.1	1.2	0.8	0.6	0.7
Whole body fat-free mass	0.9	4.9	15.2	-2.8	-1.8	-1.9	-2.1	-2.2	-2.0	1.4	1.8	-1.9	-0.5	-1.6	-2.6	-1.3	-3.9	-1.0	-2.4	-2.2	-2.0	-2.2	-2.4	-1.6	-1.7	-3.1	-2.9	-3.2	-2.2
Eye problems/disorders: Cataract	0.9	1.1	2.6	-1.1	-1.1	-1.6	-1.1	0.7	-1.1	1.3	0.8	-1.2	0.1	-1.2	-1.1	-0.4	-0.4	-0.5	1.3	-1.0	-1.2	-1.3	-1.3	-1.3	-1.3	-1.4	0.1	-0.6	-0.6
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.8	0.8	1.2	0.4	1.4	0.9	1.2	-1.2	-1.5	0.9	0.9	0.3	0.6	1.4	-1.0	0.8	0.1	1.7	1.1	1.3	0.5	1.2	1.3	-0.9	-0.1	-0.7	-0.2
Arm fat-free mass (left)	0.9	4.4	15.7	-2.8	-1.4	-1.8	-2.0	-2.2	-2.3	1.5	1.6	-1.4	-0.7	-0.8	-2.4	-1.2	-4.0	-0.9	-2.6	-2.1	-1.7	-2.0	-2.1	-1.5	-1.4	-3.5	-2.5	-2.7	-2.0
Risk taking	0.9	1.3	3.9	1.2	1.1	2.0	0.9	0.4	0.8	-0.6	-0.7	1.2	1.4	1.2	0.9	1.2	1.6	0.8	1.3	1.0	1.2	1.0	1.3	1.0	1.2	1.4	1.1	1.3	0.3
Arm predicted mass (left)	0.9	4.4	15.9	-2.7	-1.3	-1.7	-2.0	-2.2	-2.2	1.3	1.5	-1.3	-0.6	-0.7	-2.5	-1.2	-4.0	-0.9	-2.9	-2.0	-1.6	-2.0	-2.0	-1.4	-1.3	-3.5	-2.6	-2.7	-2.1
Relative age voice broke	0.8	1.2	3.7	-1.6	-0.5	-1.5	-1.2	0.4	-1.3	0.8	1.0	-0.6	-0.1	0.0	-1.1	-0.4	-1.8	-0.6	-1.9	-1.0	-1.0	-1.0	-1.1	-0.7	-0.9	-0.9	-1.2	-1.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	5.5	1.5	1.0	1.6	1.8	1.1	1.7	-1.9	-1.9	0.7	2.3	-0.3	1.2	1.6	-0.8	1.7	0.8	1.7	1.2	1.4	0.7	1.2	1.3	-1.1	0.4	0.2	0.7
Qualifications: CSEs or equivalent	0.8	1.0	2.8	1.2	0.9	1.7	1.2	0.6	1.3	-1.6	-1.1	0.8	0.8	0.3	1.1	1.3	0.3	1.4	0.5	1.0	1.1	0.9	1.0	1.4	0.6	0.7	0.2	0.1	0.5
Pulse wave reflection index	0.8	0.9	3.2	-0.6	-0.7	-1.3	-0.3	-0.9	-0.0	-0.2	-0.1	-1.0	-0.2	-1.5	-0.8	-0.6	-1.8	-0.3	-1.1	-0.5	-0.7	-0.7	-1.3	-0.6	-0.9	-1.7	-1.4	-1.4	-0.8
Medication: Blood pressure	0.8	1.4	5.0	-1.5	-0.9	-0.7	-1.1	0.5	-1.4	1.1	1.1	-1.0	0.8	-0.6	-1.1	-1.1	-1.7	-0.4	-2.2	-1.0	-1.2	-0.9	-1.3	-1.0	-0.9	-1.4	-1.5	-1.5	-1.4
Illnesses of siblings: Diabetes	0.8	1.0	2.4	-1.2	-0.8	-1.2	-1.5	-0.9	-1.6	1.4	1.1	-0.6	-1.1	0.2	-1.0	-0.0	0.6	-1.4	-0.2	-1.5	-1.0	-1.2	-0.5	-1.3	-1.0	-0.0	-0.6	-0.1	-0.6
Diabetes diagnosed by doctor	0.8	1.2	2.7	-1.3	-1.2	-0.6	-1.2	-1.6	-1.4	1.1	1.2	-1.1	-0.9	-0.9	-1.4	-1.2	-0.8	-0.6	-0.6	-1.3	-1.2	-1.2	-1.0	-1.1	-1.1	-1.4	-0.8	-0.9	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	3.5	1.3	1.2	0.6	1.0	-0.0	0.7	-0.7	-1.0	0.9	-0.7	0.6	1.0	0.4	1.9	0.5	0.3	1.0	0.9	1.0	1.1	0.7	1.0	1.3	0.5	1.0	0.9
Back pain experienced in last month	0.8	1.1	3.3	-1.5	-1.3	-0.9	-1.8	-1.2	-1.6	1.1	1.7	-0.5	-0.8	0.4	-1.4	-1.4	-0.1	-0.8	0.0	-1.8	-0.9	-1.3	-0.5	-1.0	-1.0	-0.4	0.2	-0.1	0.3
Whole body water mass	0.8	4.6	14.5	-2.7	-1.8	-1.9	-2.0	-2.1	-2.0	1.4	1.8	-1.9	-0.4	-1.5	-2.6	-1.2	-3.8	-1.0	-2.3	-2.1	-1.9	-2.1	-2.4	-1.5	-1.7	-3.0	-2.8	-3.1	-2.1
Pain type(s) experienced in last month: Hip pain	0.8	1.1	5.3	-1.2	-0.9	-1.5	-0.7	-0.6	-0.7	0.7	0.6	-0.7	-0.8	-0.7	-0.7	-0.4	-2.3	-0.7	-0.5	-0.7	-0.7	-0.8	-1.0	-0.6	-1.0	-1.8	-1.2	-1.6	-1.2
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.8	-0.7	-1.6	-0.9	-0.8	0.0	-0.7	1.4	1.1	-1.3	-1.2	-1.6	-0.5	-0.2	-0.4	-1.4	1.7	-0.8	-1.1	-0.9	-1.0	-1.1	-1.3	-0.7	-0.3	-0.8	-0.7
Coronary Artery Disease (CAD)	0.7	0.8	3.7	0.7	0.6	0.3	0.3	-0.9	0.2	-0.4	-0.4	0.9	-1.3	1.0	0.2	-0.5	1.3	0.2	1.7	0.4	0.8	0.4	0.9	0.3	0.8	0.8	1.9	1.2	1.5
Lupus	0.7	1.0	4.9	0.4	1.1	1.1	-0.0	1.5	0.2	0.1	-0.2	1.5	1.1	2.2	0.3	-0.5	1.5	0.8	-0.4	0.0	1.0	0.5	1.5	-0.0	1.6	1.2	1.2	0.9	1.0
Triglycerides	0.7	1.1	4.0	-1.0	-0.3	-1.4	-0.5	-0.5	-0.9	0.6	0.1	-0.5	-2.0	-0.5	-0.6	-0.4	-1.8	-1.1	-1.7	-0.5	-0.6	-0.6	-0.8	-0.8	-0.4	-2.0	-1.1	-1.5	-1.3
Medication: Metformin	0.7	1.0	4.5	-1.0	-0.6	-0.5	-1.1	-1.8	-1.5	1.1	1.1	-0.6	-2.1	-0.0	-0.9	-1.0	-0.4	-1.1	-0.7	-1.1	-0.8	-0.9	-0.5	-0.8	-0.7	-0.5	-0.6	-0.6	-0.8
Heart attack	0.7	0.8	2.3	-1.1	-1.5	-0.2	-1.3	0.4	-1.1	0.9	1.5	-1.3	0.2	-0.9	-0.9	-0.9	-0.1	-0.7	-0.1	-1.1	-1.3	-1.1	-1.0	-0.9	-1.2	-0.1	0.0	-0.4	-0.4
Exposure to tobacco smoke outside home	0.7	0.9	4.0	-0.6	-1.6	-0.6	-1.0	-0.1	-0.7	0.4	0.9	-1.6	-0.2	-2.0	-0.9	-0.4	0.7	-0.6	0.5	-1.1	-1.4	-1.2	-1.0	-1.0	-1.3	-0.3	0.0	-0.2	-0.7
Medication: Omeprazole	0.7	0.9	5.0	-1.1	-0.1	-0.6	-0.7	-0.7	-0.8	1.0	0.7	-0.2	0.6	0.2	-0.7	-1.6	-1.5	-0.5	-2.2	-0.6	-0.5	-0.7	-0.7	-0.8	-0.2	-0.6	-1.4	-1.0	-1.4
Illnesses of father: Heart disease	0.7	1.0	4.8	0.6	0.8	2.2	0.4	0.7	0.4	-0.5	-0.2	1.0	2.2	1.3	0.4	1.0	0.6	1.6	0.7	0.4	0.8	0.5	1.1	0.7	0.6	1.3	0.4	0.8	0.7
Guilty feelings	0.7	1.0	2.4	-1.3	-0.9	-0.9	-1.5	-0.9	-1.4	1.5	1.2	-0.7	-0.2	-0.1	-1.3	-1.0	-0.7	-0.3	-0.3	-1.5	-1.0	-1.2	-0.8	-1.4	-1.3	-0.7	-0.3	-0.4	0.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.2	-1.1	-1.5	-0.4	-1.3	0.3	-1.2	0.9	1.5	-1.3	0.0	-0.9	-1.0	-1.0	-0.3	-0.7	-0.2	-1.1	-1.3	-1.2	-1.0	-0.9	-1.2	-0.1	-0.0	-0.5	-0.5
HbA1C	0.6	0.7	1.8	-1.0	-1.4	-0.8	-1.0	-0.8	-1.0	0.0	1.2	-0.9	-1.0	-0.7	-0.7	-1.3	-1.0	-0.2	-0.6	-1.2	-0.7	-0.9	-0.5	-1.1	-0.7	-0.5	-0.1	-0.2	-0.5
Rheumatoid Arthritis	0.6	0.9	6.4	-0.9	-0.7	-1.1	-1.0	-0.8	-1.1	1.0	0.3	-0.7	0.3	-0.4	-1.1	-0.2	-1.1	-0.5	-0.1	-1.1	-0.8	-1.0	-0.8	-1.4	-0.9	-2.5	0.1	0.5	-0.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.1	-0.8	-0.3	-1.0	-0.7	-1.5	-0.9	0.7	0.4	-0.4	-1.2	-0.0	-1.0	-1.3	-0.9	-0.9	-0.9	-0.8	-0.5	-0.6	-0.6	-1.0	-0.4	-1.4	-0.2	-0.2	-0.4
Medication for hormone replacement therapy	0.6	0.6	2.3	0.5	1.1	1.2	0.5	0.4	0.4	-0.3	-0.4	1.2	0.9	1.5	0.4	-0.2	0.2	0.4	-1.2	0.6	0.9	0.9	1.0	0.7	1.3	0.6	0.5	0.7	0.6
Maternal smoking around birth	0.6	0.8	4.2	0.6	0.3	1.5	0.3	1.9	0.4	-0.4	0.0	0.6	2.1	0.8	0.9	1.3	1.1	0.6	1.1	0.4	0.5	0.4	0.8	0.8	0.4	0.8	0.6	0.8	0.1
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.1	1.6	1.1	1.6	1.4	-0.5	1.6	-1.1	-1.1	1.0	0.5	0.4	1.0	1.3	1.6	1.1	0.6	1.2	1.2	1.0	1.0	1.1	0.8	1.8	0.6	1.0	0.2
Body mass index (BMI)	0.6	2.7	13.9	0.8	1.8	0.1	1.4	2.2	1.9	-2.1	-1.9	1.6	3.7	1.3	1.2	1.5	-1.5	3.0	0.6	1.3	1.5	1.5	0.9	1.5	1.7	-0.5	0.4	0.6	1.5
Nervous feelings	0.6	1.1	2.7	1.2	0.5	0.7	1.1	1.2	1.3	-1.4	-0.8	0.7	0.9	0.2	1.2	0.8	1.0	1.6	1.6	1.0	0.9	1.1	0.9	1.0	0.8	0.6	1.1	0.9	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	3.5	-1.0	-0.8	-1.1	-0.7	0.4	-0.8	0.2	0.4	-1.1	0.9	-1.3	-0.6	0.0	-1.7	0.5	-1.0	-0.8	-0.9	-0.7	-1.2	-0.6	-1.2	-1.9	-1.2	-1.2	-0.6
Happiness	0.6	0.7	2.4	-1.0	-0.7	-0.0	-0.9	-0.6	-0.8	0.5	1.0	-0.7	-0.7	-0.5	-1.0	-1.4	-1.0	-0.5	-1.5	-0.8	-0.7	-0.9	-0.6	-0.6	-0.6	-0.7	-0.8	-0.8	-0.9
Eye problems/disorders: None of the above	0.6	0.7	3.9	-0.8	-0.6	0.1	-0.8	-1.5	-0.8	0.6	1.0	-0.6	-1.0	-0.0	-0.7	-0.4	-0.7	-0.6	-2.0	-1.0	-0.6	-0.6	-0.5	-0.3	-0.7	0.7	-1.5	-1.0	-0.7
Heart disease (mother)	0.6	0.7	3.7	0.6	0.5	1.1	0.6	1.9	0.3	-0.6	-0.5	0.8	0.8	0.9	1.3	1.3	0.1	0.9	0.7	0.7	0.7	0.8	0.9	1.0	0.7	-0.3	0.8	0.5	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	4.2	-0.4	-0.1	0.0	-0.4	-2.1	-0.5	0.3	0.6	0.0	-2.0	0.2	-0.6	-1.1	-0.5	-0.9	-1.4	-0.5	-0.1	-0.3	-0.2	-0.4	-0.3	-0.1	-1.2	-1.0	-1.0
Hypertension (Self-reported)	0.6	1.6	8.1	-1.5	-0.9	-1.4	-0.8	-0.0	-1.0	0.5	0.6	-1.1	0.6	-1.2	-1.2	-1.1	-2.9	-0.3	-1.6	-0.9	-1.1	-0.9	-1.7	-1.0	-0.8	-2.3	-1.3	-1.7	-1.1
Friendships satisfaction	0.6	0.7	1.7	-1.0	-0.7	-1.3	-1.1	-0.3	-1.1	1.1	1.1	-0.4	-1.0	0.0	-1.0	-1.2	0.1	-1.1	-0.8	-1.0	-0.7	-0.8	-0.4	-1.1	-0.3	-0.4	-0.6	-0.4	-0.7
Eye problems/disorders: Glaucoma	0.6	0.8	2.7	0.9	0.7	0.5	1.1	0.9	1.1	-1.4	-1.4	0.5	1.3	-0.1	0.7	0.5	-0.3	1.6	0.7	1.1	0.7	0.7	0.3	0.8	0.7	-0.7	1.0	0.7	0.5
Medication: Blood pressure	0.6	1.1	4.2	-0.9	-1.3	-1.9	-0.4	-0.0	-0.6	0.5	0.3	-1.4	-0.3	-2.0	-0.9	-0.8	-1.8	-0.5	-0.3	-0.5	-1.1	-0.8	-1.6	-0.9	-0.9	-1.7	-0.6	-1.2	-0.4
Depressed Affect (Nagel 2018)	0.5	1.0	2.3	-0.9	-0.6	-1.0	-1.3	-1.5	-1.2	1.1	0.9	-0.4	-1.4	0.4	-0.9	-1.5	0.2	-0.7	-0.5	-1.4	-0.6	-1.1	-0.2	-1.3	-0.9	-1.0	0.5	0.9	0.9
Blood White Count	0.5	3.5	12.9	1.3	2.5	2.5	1.3	0.8	0.7	-1.5	-1.5	2.8	1.0	3.6	1.4	0.2	1.0	2.2	0.2	1.7	2.2	1.7	2.2	1.9	2.5	1.4	2.4	2.1	1.3
Lung FVC	0.5	2.6	10.7	1.0	1.6	2.0	0.6	-1.2	0.3	-0.3	-0.4	2.2	-0.5	3.3	1.2	0.1	1.7	0.4	0.9	0.5	1.7	1.2	2.3	1.6	1.8	2.4	1.8	2.2	2.6
Hand grip strength (right)	0.5	1.4	8.5	0.1	0.7	1.7	-0.5	0.1	-0.5	0.7	0.7	1.4	-0.6	2.5	0.3	-0.0	2.1	-0.6	0.4	-0.2	0.8	0.2	1.6	0.4	0.9	2.9	1.2	1.2	1.1
Serious illness, injury or assault to yourself	0.5	0.7	3.3	-1.0	-0.8	-0.2	-0.7	0.1	-0.8	0.7	1.0	-0.4	-1.0	-0.1	-0.4	-1.3	-1.1	-0.8	-1.8	-0.6	-0.6	-0.6	-0.6	-0.5	-0.4	0.2	-0.9	-0.8	-1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.1	-0.8	-0.7	-1.0	-0.7	-0.4	-0.6	0.5	0.6	-0.7	-0.9	-0.6	-0.5	-0.7	-0.7	-0.9	-1.0	-0.9	-0.7	-0.9	-0.8	-0.7	-0.4	-0.8	-0.6	-0.6	-0.8
Qualifications: None of the above	0.5	1.0	4.9	0.5	1.0	1.0	0.3	1.7	0.2	-0.7	-0.7	1.0	1.3	1.3	0.9	2.2	0.6	1.2	1.1	0.4	0.8	0.7	1.1	0.6	1.1	0.0	0.6	1.2	1.0
Pain all over the body in last month	0.5	0.6	2.7	0.2	0.4	1.1	-0.3	0.8	-0.4	0.2	0.1	0.4	1.2	1.2	0.3	0.8	1.6	0.3	0.3	-0.3	0.2	0.2	0.9	0.2	0.1	1.1	0.8	1.5	1.1
Birth weight of first child	0.5	0.9	8.5	-0.4	0.8	-0.2	0.1	-1.1	0.0	-0.2	0.2	0.9	-0.8	1.4	-0.4	-2.2	-1.6	0.3	-2.9	0.2	0.5	0.3	0.1	0.2	0.5	-0.1	-0.7	-0.4	-0.5
Birth weight	0.5	1.0	3.5	0.9	0.4	1.5	0.7	1.4	0.9	-0.7	-0.5	0.5	1.9	0.1	0.7	1.0	1.3	1.3	1.4	0.9	0.6	0.5	0.7	0.8	0.7	1.6	1.1	0.7	0.2
Qualifications: College or University degree	0.5	1.5	5.9	-1.4	-0.7	-1.8	-1.3	-1.3	-1.4	1.6	1.1	-0.8	-2.0	-0.1	-1.2	-1.2	-0.8	-2.4	-1.1	-1.3	-1.0	-1.1	-1.0	-1.2	-0.9	-0.5	-0.6	-0.7	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.5	1.0	0.7	0.5	0.8	-0.6	1.0	-0.8	-0.8	0.4	0.3	0.3	0.5	0.5	1.0	0.7	1.0	0.5	0.6	0.7	0.5	0.5	0.4	1.0	0.9	1.2	0.9
Chest pain or discomfort	0.5	0.7	4.2	0.5	0.5	0.8	0.5	2.1	0.7	-0.4	-0.4	0.7	1.5	0.6	0.9	1.4	0.4	1.0	0.9	0.6	0.6	0.7	0.7	0.9	0.7	1.1	0.7	0.3	0.5
Leg fat-free mass (right)	0.5	2.6	10.0	-2.0	-1.6	-1.5	-1.4	-1.4	-0.9	0.8	1.4	-1.5	0.4	-1.5	-1.9	-0.9	-3.2	-0.3	-1.2	-1.6	-1.4	-1.5	-1.9	-1.0	-1.3	-2.0	-2.1	-2.6	-1.5
Mood swings	0.5	0.9	2.9	0.6	0.9	0.8	0.5	0.8	0.6	-0.7	-0.6	1.3	0.5	1.6	0.6	0.4	0.5	0.9	0.4	0.6	1.0	0.9	1.2	0.6	1.1	-0.3	1.5	1.7	1.7
Long-standing illness, disability or infirmity	0.5	0.8	2.0	0.9	0.9	1.2	1.1	1.4	1.0	-0.8	-1.1	0.8	1.2	0.4	1.3	0.8	-0.2	1.1	0.3	1.1	0.9	1.1	0.9	1.1	0.7	0.1	0.7	0.2	0.7
Leg predicted mass (right)	0.5	2.5	9.7	-2.0	-1.5	-1.5	-1.4	-1.4	-0.9	0.8	1.4	-1.5	0.4	-1.5	-1.9	-0.8	-3.1	-0.3	-1.2	-1.6	-1.4	-1.5	-1.9	-1.0	-1.3	-2.0	-2.1	-2.5	-1.4
Commuting to job workplace: Public transport	0.5	0.6	1.5	0.8	0.3	1.2	0.7	0.7	0.8	-0.8	-0.6	0.6	0.8	0.6	0.9	-0.1	0.8	0.3	0.7	0.6	0.8	0.7	0.8	0.7	0.8	0.5	1.2	1.2	1.0
Commuting to job workplace: Cycle	0.5	0.6	7.4	-0.1	-0.0	0.2	-0.4	-2.7	-0.3	0.6	0.8	0.4	-1.2	1.0	-0.9	-1.1	0.9	-0.1	-0.4	-0.4	0.0	-0.4	0.1	-0.6	-0.1	1.1	0.1	0.5	-0.4
Cholesterol lowering medication	0.5	0.8	2.2	0.8	0.5	0.8	1.0	1.0	0.9	-1.3	-1.0	0.6	0.8	-0.0	0.8	1.2	-0.2	1.5	1.1	1.0	0.8	0.7	0.7	1.2	0.9	-0.4	0.8	0.3	0.7
Heart disease (siblings)	0.5	0.6	3.3	0.5	0.6	1.1	0.4	0.5	0.5	-0.5	-0.2	0.5	1.3	0.7	0.7	1.8	0.7	0.8	0.5	0.2	0.5	0.6	0.7	0.8	0.7	1.3	-0.4	-0.1	0.4
Crohns Disease (2012)	0.4	0.6	2.0	0.8	0.6	0.2	0.6	0.7	0.7	-0.8	-0.7	0.6	-0.2	0.6	0.9	0.8	1.4	0.5	0.5	0.6	0.6	0.6	0.8	0.7	0.5	1.1	0.9	1.2	0.9
Neuroticism (2016)	0.4	0.5	2.1	-0.6	-0.1	-0.1	-0.1	-0.1	-0.3	-0.1	0.1	-0.6	1.3	-0.8	-0.7	-0.1	-1.4	0.2	-1.3	-0.1	-0.5	-0.2	-1.0	-0.2	-0.4	-1.0	-1.1	-1.4	-1.0
Smoking Status	0.4	0.8	4.2	-0.8	-0.5	-0.5	-0.8	-2.1	-1.0	0.7	0.7	-0.5	0.1	-0.2	-1.8	-1.5	-0.2	-0.5	-1.0	-0.7	-0.7	-0.9	-0.8	-1.2	-0.3	-0.8	-0.4	-0.3	-1.3
Neuroticism	0.4	1.1	2.1	-1.1	-0.9	-1.1	-1.3	-1.4	-1.1	1.0	1.1	-0.9	-0.8	-0.4	-1.3	-1.4	-0.3	-0.8	-1.1	-1.4	-1.0	-1.2	-0.9	-1.3	-1.3	-0.8	-0.8	-0.6	-0.2
Supplements: Zinc	0.4	0.4	2.8	-0.6	0.2	-1.4	-0.1	0.3	-0.4	0.5	-0.2	-0.3	-0.1	-0.6	-0.6	-0.6	-1.7	-0.5	0.1	-0.1	-0.3	-0.1	-0.6	-0.5	-0.3	-1.3	-0.4	-1.0	-0.4
Hair/balding pattern: Pattern 2	0.4	0.5	3.0	0.2	-0.4	-0.0	-0.4	-0.4	-0.4	0.4	0.3	-0.4	-1.3	-0.2	-0.0	-0.4	1.7	-0.8	0.7	-0.4	-0.4	-0.3	0.1	-0.5	-0.3	0.8	1.0	1.2	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	3.6	1.2	0.9	1.4	1.3	0.7	1.1	-1.2	-1.4	0.7	1.9	0.0	0.8	1.1	-0.1	1.2	0.7	1.3	0.9	0.9	0.7	0.7	1.0	-1.2	0.4	0.5	0.5
Medication: Simvastatin	0.4	0.6	2.9	0.3	0.4	1.3	0.7	0.8	0.6	-0.9	-0.8	0.6	1.7	0.1	0.3	0.9	-1.3	1.4	0.2	0.8	0.7	0.6	0.3	1.0	0.6	-0.8	0.6	0.0	0.2
Father’s age at death	0.4	0.6	1.4	1.0	0.5	0.6	0.8	0.1	0.8	-0.3	-0.5	0.7	-0.7	0.6	0.9	0.3	1.2	0.2	0.8	0.8	0.7	0.9	0.9	0.8	0.5	1.2	1.2	0.6	0.8
Medication: Amlodipine	0.4	0.6	3.6	0.1	0.9	0.0	0.8	1.1	0.6	-0.3	-0.8	0.6	1.4	0.3	0.3	0.2	-1.9	0.7	-0.6	0.9	0.7	0.7	0.1	0.7	0.9	-0.5	-0.6	-0.9	-0.1
Medication: Ibuprofen	0.4	0.5	4.2	-0.4	0.5	0.6	-0.3	0.3	-0.2	-0.4	0.0	0.4	2.1	1.1	-0.0	0.8	-0.6	2.0	0.3	-0.4	0.2	-0.1	0.3	0.4	-0.1	-0.0	-0.0	0.4	0.8
Knee pain experienced in last month	0.4	0.6	1.4	0.5	0.9	0.2	0.9	0.4	0.8	-0.8	-0.9	1.2	0.5	1.0	0.5	0.4	-0.8	1.1	0.7	0.9	1.1	0.8	0.7	1.0	0.7	-0.1	1.2	0.3	0.7
Hearing aid user	0.4	0.5	2.7	-0.5	0.3	-1.0	-0.0	-1.3	-0.2	-0.3	-0.2	0.2	0.9	0.4	-0.7	-0.6	-1.6	0.9	-0.8	-0.1	0.2	-0.1	-0.3	0.3	-0.1	-1.6	-0.3	-0.3	0.1
Myopia	0.4	0.6	2.3	0.4	1.2	-0.6	0.7	-0.9	0.4	-0.2	-1.0	1.3	-0.6	1.5	0.2	-0.7	-0.8	0.0	0.0	0.7	1.1	0.8	0.7	0.2	1.2	-1.5	0.3	0.3	0.4
Depression (Nagel 2018)	0.3	0.5	1.8	-0.8	-0.7	-0.4	-0.7	-0.4	-0.9	0.8	0.7	-0.2	-1.1	-0.0	-0.6	-1.1	-0.7	-0.6	-0.8	-0.7	-0.4	-0.6	-0.3	-0.7	-0.3	-1.3	0.1	-0.5	-0.2
Neuroticism (Nagel 2018)	0.3	0.8	2.1	-0.9	-0.8	-0.9	-1.2	-1.4	-1.0	0.9	0.8	-0.7	-0.6	-0.2	-1.0	-1.2	-0.1	-0.5	-0.3	-1.4	-0.8	-1.2	-0.5	-1.4	-1.2	-1.0	-0.1	0.4	0.4
Ulcerative Colitis (UC)	0.3	0.6	3.2	0.2	0.2	-0.0	-0.4	-0.8	-0.2	0.4	0.4	0.3	-0.5	0.9	-0.3	-1.2	1.7	-0.5	-0.4	-0.3	0.1	-0.0	0.5	-0.5	-0.3	1.4	1.2	1.8	0.8
Body Mass Index (BMI) (2010)	0.3	0.4	3.3	0.5	0.6	-0.3	0.6	0.8	0.5	-1.1	-0.6	0.2	1.8	0.0	0.4	0.2	0.1	1.2	0.1	0.6	0.3	0.5	0.2	0.5	0.4	0.0	0.2	0.6	0.8
Fasting Glucose	0.3	0.4	1.6	-0.7	-1.0	-0.4	-0.4	-0.0	-0.3	0.4	0.9	-0.0	-0.5	-0.6	0.1	-0.2	-1.3	-0.4	-0.4	-0.6	-0.5	-0.2	-0.6	-0.2	-0.3	-0.3	-1.0	-1.3	-0.7
Ulcerative Colitis	0.3	0.5	4.0	0.4	-0.3	0.3	-0.1	-0.7	-0.2	0.4	0.3	-0.4	-1.2	-0.4	-0.0	-0.8	2.0	-0.8	-0.2	-0.1	-0.3	-0.1	0.2	-0.4	-0.4	1.2	0.8	1.1	0.3
Systolic Blood Pressure	0.3	1.5	8.9	-1.2	-0.9	-1.1	-0.5	0.7	-0.8	0.7	0.2	-1.1	0.6	-1.4	-0.6	0.1	-3.0	-0.7	-0.5	-0.6	-0.8	-0.6	-1.3	-0.6	-0.9	-3.0	-1.7	-2.1	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.3	-0.5	-0.5	0.5	-0.6	-1.0	-0.5	0.3	0.9	-0.3	-1.1	0.0	-0.6	-0.7	0.0	-0.3	-0.8	-0.6	-0.4	-0.6	-0.1	0.0	-0.5	0.7	-0.1	-0.2	-0.4
Angina	0.3	0.4	1.6	-0.4	-1.3	0.7	-0.8	0.7	-0.9	0.8	1.1	-0.6	0.3	-0.3	-0.3	-0.1	1.0	-0.4	0.5	-0.7	-0.7	-0.6	-0.2	-0.3	-0.4	0.9	0.5	-0.1	0.0
Severe depression (siblings)	0.3	0.3	1.3	0.1	1.1	-0.3	0.5	0.1	0.5	-0.5	-0.7	1.1	-0.1	1.1	-0.1	0.2	-0.6	0.5	0.2	0.6	0.7	0.6	0.5	0.2	0.9	-0.5	0.4	0.1	0.1
Current tobacco smoking	0.3	0.5	1.9	0.3	0.9	0.8	0.4	0.5	0.3	-0.8	-0.2	0.9	1.4	1.1	0.3	0.4	0.2	1.3	-0.2	0.6	0.7	0.7	0.7	0.8	1.0	0.7	0.0	0.1	-0.0
Taking other prescription medications	0.3	0.4	2.1	0.1	0.4	1.0	0.1	1.5	0.0	-0.0	-0.0	0.7	1.1	0.9	0.6	0.6	0.1	0.8	0.3	0.2	0.4	0.4	0.7	0.6	0.6	0.8	0.8	0.7	0.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.1	0.3	0.4	0.0	0.4	1.0	0.3	-0.7	-0.6	0.4	0.7	0.3	0.5	0.2	-0.4	0.6	0.1	0.5	0.5	0.5	0.4	0.2	0.7	-1.0	0.6	0.6	0.7
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.9	-0.5	-0.8	-0.1	-0.8	-0.4	-0.6	0.4	0.8	-0.5	-0.3	-0.3	-0.8	-0.7	0.7	-0.4	0.3	-0.7	-0.7	-0.9	-0.4	-0.5	-0.6	0.6	0.1	-0.3	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.4	0.6	0.1	0.9	0.4	0.6	0.6	-0.4	0.0	0.6	0.1	0.4	0.5	0.0	0.7	0.4	0.9	0.4	0.6	0.6	0.8	0.7	0.6	0.7	1.2	0.6	1.2
Diabetes (self-reported)	0.3	0.4	1.3	-0.7	-0.6	-0.3	-0.8	-1.2	-0.9	0.5	0.9	-0.4	-0.8	-0.1	-0.8	-1.0	-0.1	-0.1	-0.2	-0.8	-0.7	-0.7	-0.4	-0.6	-0.6	-0.5	-0.1	-0.2	-0.2
Medication: Cholesterol lowering	0.3	0.4	3.3	0.0	0.5	1.8	0.2	0.3	0.0	-0.0	-0.2	0.7	1.5	1.0	0.2	0.2	-0.7	0.6	-0.8	0.4	0.5	0.5	0.4	0.7	0.4	0.2	0.5	0.2	0.2
Medication: Lansoprazole	0.3	0.4	1.5	-0.6	-0.2	-1.2	-1.0	-0.0	-1.0	0.9	0.6	-0.2	0.3	0.5	-0.9	0.4	0.7	-0.2	0.2	-0.9	-0.5	-0.6	-0.3	-0.8	-0.4	-0.5	0.4	0.7	0.6
Hair/balding pattern: Pattern 4	0.3	0.8	3.5	-0.8	0.5	-0.9	-0.4	-1.8	-0.9	0.7	0.0	0.8	0.0	1.5	-0.9	-1.5	-1.4	-0.4	-1.9	-0.4	0.2	-0.1	-0.1	-0.6	0.6	-1.6	-0.4	-0.0	0.1
Loud music exposure frequency	0.3	0.3	1.1	0.6	0.1	-0.2	0.4	-0.2	0.7	-0.4	-0.4	0.2	-0.0	0.1	0.6	0.5	1.0	-0.0	1.0	0.3	0.3	0.5	0.4	0.3	0.3	1.0	0.6	0.8	0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.6	-0.3	-1.3	0.1	-0.3	-0.3	-0.3	0.0	0.7	-1.0	-0.7	-1.2	0.2	-0.7	-0.4	-0.3	-0.3	-0.5	-0.8	-0.4	-0.7	-0.3	-0.9	-0.3	-0.4	-0.5	-0.3
Medication: Paracetamol	0.3	0.5	2.5	-0.0	-0.1	1.1	0.1	1.3	0.1	-0.5	-0.1	-0.0	1.6	-0.1	0.6	0.3	-1.1	1.5	0.6	0.0	0.1	0.1	0.0	0.5	-0.4	-0.7	0.5	0.8	0.6
Headache pain in last month	0.3	0.4	2.6	-0.8	-0.2	-0.0	-0.7	1.6	-0.4	0.5	0.7	-0.3	1.6	0.2	-0.1	-0.1	-0.4	-0.1	-1.2	-0.6	-0.5	-0.4	-0.4	-0.4	-0.2	0.4	-1.0	-0.6	-0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.6	0.9	0.3	-0.5	0.4	-0.7	0.6	-0.5	-0.4	0.4	-0.9	0.2	0.4	0.5	1.5	-0.2	1.6	0.3	0.5	0.3	0.7	0.1	0.3	0.6	0.8	1.0	0.9
Suffer from ‘nerves’	0.3	0.5	1.4	-0.9	-1.0	-0.6	-1.0	-0.5	-0.6	0.1	1.2	-0.7	-1.1	-0.4	-0.6	-0.8	-0.5	-0.5	-0.7	-1.0	-0.8	-0.9	-0.6	-0.5	-0.7	-0.3	-0.8	-0.7	-0.5
Overall health rating	0.3	0.6	4.3	0.0	0.7	0.4	0.2	2.1	0.1	-0.5	-0.2	0.8	1.6	0.9	0.5	0.1	-0.4	1.1	0.1	0.3	0.6	0.6	0.6	0.5	0.8	-0.1	0.8	0.7	1.1
Age at last live birth	0.3	0.4	2.5	0.1	0.9	-0.0	0.5	-0.8	-0.1	-0.1	-0.8	0.6	-1.3	0.6	0.2	-0.6	-0.6	-0.9	-1.6	0.5	0.4	0.5	0.0	0.1	0.6	-0.8	0.0	0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.2	0.9	0.7	-0.2	0.8	0.2	0.7	-0.4	-1.0	0.7	-0.3	0.1	0.6	0.5	1.0	0.3	1.5	0.8	0.7	0.6	0.7	0.2	0.6	0.0	0.5	0.2	0.5
Smoking status: Previous	0.3	0.4	2.1	-0.5	-0.0	-0.9	-0.5	-1.4	-0.4	0.6	-0.0	-0.2	-0.1	0.1	-1.1	-0.8	-0.4	-0.5	-0.0	-0.5	-0.3	-0.7	-0.5	-1.0	-0.3	-1.0	0.2	0.3	-0.2
Loneliness, isolation	0.3	0.4	1.5	0.5	0.2	0.3	0.3	0.5	0.2	-0.3	-0.0	0.7	-0.5	0.8	0.9	-0.6	0.6	0.2	0.3	0.2	0.6	0.5	1.0	0.4	0.5	0.2	1.0	1.2	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	3.0	-0.8	-0.0	-0.2	-0.4	-1.2	-1.1	0.8	0.3	0.2	-1.1	0.5	-0.3	-1.2	-1.7	-1.0	-1.7	-0.4	-0.0	-0.4	-0.2	-0.1	-0.0	-1.5	-0.8	-0.8	-0.3
Financial situation satisfaction	0.3	0.4	1.6	-0.5	-0.6	0.2	-0.9	0.4	-0.8	0.8	1.3	-0.4	0.2	-0.1	-0.6	-0.6	1.2	-0.3	-0.5	-0.8	-0.7	-0.6	-0.2	-0.6	-0.2	1.1	-0.2	-0.2	-0.1
High cholesterol (Self-reported)	0.3	0.6	1.7	0.7	0.6	1.3	0.5	0.8	0.4	-0.7	-0.5	0.7	1.2	0.6	0.4	0.6	0.6	1.0	0.6	0.6	0.7	0.7	0.8	0.9	0.6	0.1	1.1	0.7	1.3
Medication: Paracetamol	0.3	0.5	2.8	-0.1	-0.2	0.9	-0.2	1.4	-0.2	-0.2	0.2	-0.0	1.7	0.1	0.5	0.3	-0.2	1.4	0.9	-0.3	-0.0	-0.1	0.2	0.4	-0.6	-0.2	0.9	1.1	0.8
Ever smoked	0.3	0.6	2.2	-0.6	-0.8	-0.6	-0.9	-1.5	-0.8	0.9	0.8	-0.7	-0.7	-0.4	-1.0	-1.0	0.6	-1.0	-0.4	-0.9	-0.8	-0.9	-0.7	-1.1	-0.4	-0.1	-0.2	-0.2	-0.9
Number of operations (self-reported)	0.3	0.4	1.3	-0.5	-0.7	-0.7	-0.7	-0.1	-0.9	1.1	0.6	-0.6	-0.2	-0.5	-0.4	-0.2	0.2	-0.7	0.3	-0.6	-0.8	-0.8	-0.6	-1.0	-0.3	-1.1	0.2	0.2	-0.3
Fractured/broken bones in last 5 years	0.3	0.3	1.3	-0.7	-0.0	-0.5	-0.7	-0.5	-1.0	1.1	0.4	0.2	-1.2	1.0	-0.4	-0.4	-0.3	-0.7	-0.8	-0.4	-0.2	-0.5	0.1	-0.5	0.1	-0.4	0.2	0.1	-0.1
Basal cell carcinoma (self-reported)	0.3	0.4	2.2	-0.2	0.8	0.0	-0.2	-0.8	-0.4	0.3	0.1	0.6	-1.5	1.2	-0.1	0.2	0.2	-0.6	-1.5	-0.1	0.3	-0.0	0.3	0.2	0.0	0.8	-0.5	-0.2	-0.7
Alcohol drinker status: Previous	0.3	0.4	2.8	-0.7	0.7	0.0	-0.7	0.5	-0.8	0.8	0.3	0.8	1.2	1.7	-0.6	-0.4	-0.0	0.2	-0.6	-0.3	0.2	-0.3	0.4	-0.6	0.4	0.2	0.2	0.4	-0.2
Alzheimer’s Disease (in mother)	0.2	0.2	0.8	0.7	0.1	0.5	0.5	-0.2	0.6	-0.4	-0.3	-0.1	0.7	-0.5	0.0	0.4	0.9	0.5	-0.2	0.5	0.1	0.2	0.1	0.2	0.1	0.6	-0.2	-0.1	-0.5
Prostate Cancer	0.2	0.3	0.7	-0.4	-0.8	-0.3	-0.7	0.2	-0.4	0.2	0.7	-0.8	0.3	-0.8	-0.7	-0.3	0.4	-0.3	-0.1	-0.7	-0.8	-0.6	-0.6	-0.6	-0.7	0.2	-0.0	0.1	-0.2
Age at First Birth	0.2	0.4	1.6	-0.4	-0.2	-0.3	-0.8	-0.7	-0.5	0.8	0.7	-0.4	0.4	0.2	-0.9	0.4	1.2	-0.3	0.3	-0.6	-0.5	-0.6	-0.2	-0.6	-0.5	1.3	0.4	0.4	0.2
LDL Cholesterol	0.2	0.3	1.1	-0.0	0.8	-0.9	-0.1	0.3	-0.2	-0.3	-0.4	0.6	-0.0	1.0	-0.3	0.1	0.7	-0.6	-0.5	0.1	0.3	0.3	0.4	-0.2	0.7	-0.2	0.6	0.6	0.6
Primary Biliary Cirrhosis	0.2	0.3	2.2	0.5	-0.6	-0.2	0.3	0.4	0.6	-0.3	-0.3	-0.6	0.5	-1.2	0.4	0.4	0.5	0.3	1.5	0.2	-0.2	0.1	-0.2	0.0	-0.5	-0.2	1.0	0.7	0.4
BMI	0.2	1.4	9.8	-1.4	-0.2	-1.6	-0.7	-0.6	-0.1	-0.1	0.2	-0.4	2.1	-0.2	-1.1	-0.7	-3.1	1.1	-1.6	-0.9	-0.6	-0.7	-1.4	-0.6	-0.7	-1.9	-1.6	-1.1	-0.6
Number of treatments/medications taken	0.2	0.4	2.9	-0.9	-0.6	0.1	-0.7	1.3	-0.7	0.3	0.6	-0.5	1.7	-0.4	-0.5	0.0	-1.0	0.9	-0.0	-0.6	-0.7	-0.5	-0.7	-0.2	-0.5	-0.1	-0.1	-0.3	-0.0
Ever had hysterectomy (womb removed)	0.2	0.2	1.2	-0.7	-0.4	-1.1	-0.5	0.3	-0.6	0.3	0.3	-0.3	-0.3	0.1	-0.3	0.2	-0.7	-0.4	-0.6	-0.4	-0.4	-0.4	-0.3	-0.6	-0.2	-1.0	0.3	0.1	-0.4
Systolic blood pressure, automated reading	0.2	0.5	2.2	0.4	0.3	-0.2	0.9	1.5	0.7	-0.6	-0.9	0.3	0.2	-0.4	0.7	0.6	-1.2	0.2	0.6	0.9	0.4	0.7	0.0	0.5	0.8	-1.3	-0.2	-0.8	0.3
Townsend deprivation index at recruitment	0.2	0.3	1.2	0.2	-0.2	-0.3	0.5	1.0	0.8	-0.4	-0.4	-0.2	0.1	-0.9	0.7	0.8	-1.1	-0.2	-0.3	0.3	0.0	0.4	-0.2	0.2	-0.1	-0.6	-1.0	-0.7	-0.2
Alcohol usually taken with meals	0.2	0.4	2.2	0.7	0.4	-0.3	0.9	-1.2	0.5	-0.3	-0.7	0.3	-1.5	-0.3	0.3	-0.6	-0.3	-0.2	-0.4	0.9	0.5	0.4	0.2	0.4	0.4	-0.9	0.3	0.0	-0.1
Had other major operations	0.2	0.3	1.9	0.2	-0.3	0.1	-0.0	0.6	-0.2	0.4	0.2	0.2	-0.5	0.4	1.0	0.5	0.7	-0.4	1.4	-0.1	0.1	0.1	0.4	0.2	0.2	0.2	0.9	0.8	0.7
Financial difficulties in last 2 years	0.2	0.3	2.9	0.2	-0.2	0.6	0.2	1.7	0.4	-0.3	-0.0	-0.1	1.4	-0.5	0.7	0.9	0.1	0.3	0.9	0.2	0.1	0.2	0.2	0.3	0.3	0.0	0.5	0.1	0.5
Medication: Ramipril	0.2	0.3	1.2	-0.6	-0.0	-0.8	-0.2	-0.3	-0.7	0.8	0.4	0.1	-0.7	0.5	-0.5	-1.0	-1.1	-0.5	-0.9	-0.1	-0.1	0.1	-0.3	-0.5	-0.0	-0.8	-0.4	-0.4	-0.3
Illnesses of siblings	0.2	0.3	2.9	-0.3	-0.8	0.3	-0.4	-0.5	-0.0	0.5	0.6	-0.4	-0.2	-0.7	-0.6	-1.7	-0.5	-0.2	0.5	-0.2	-0.3	-0.6	-0.4	-0.4	-0.5	-0.4	0.4	-0.3	-0.1
Neuroticism score	0.2	0.4	1.3	-0.8	-0.7	-0.5	-1.0	-0.4	-0.7	0.6	0.9	-0.5	-0.1	0.0	-0.8	-1.2	-0.4	-0.3	-0.5	-1.0	-0.6	-0.7	-0.5	-0.9	-0.8	-0.6	-0.1	-0.1	0.3
Alcohol intake versus 10 years previously	0.2	0.3	0.9	-0.7	-0.8	-0.1	-0.9	0.5	-0.7	0.4	0.9	-0.6	0.8	-0.2	-0.2	-0.1	0.1	0.0	-0.1	-0.9	-0.7	-0.8	-0.5	-0.5	-0.9	-0.0	-0.4	0.2	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	2.1	-0.6	-0.1	0.2	-0.5	-0.0	-0.4	-0.0	0.3	-0.3	1.5	0.2	-0.1	0.4	-0.8	1.3	0.2	-0.7	-0.3	-0.5	-0.2	0.0	-0.6	-0.3	-0.5	0.0	0.6
Depression (self-reported)	0.2	0.2	0.5	0.5	0.6	0.6	0.5	-0.1	0.3	-0.4	-0.7	0.6	0.5	0.3	0.2	0.2	0.1	0.4	0.1	0.5	0.5	0.4	0.3	0.4	0.6	-0.4	0.7	0.2	0.0
Lung cancer (father)	0.2	0.2	1.4	0.6	0.5	0.3	0.6	-0.1	0.3	-0.7	-0.8	0.1	0.4	-0.3	0.4	-0.1	0.1	0.6	-0.1	0.5	0.3	0.3	0.3	0.2	0.2	-1.2	0.2	0.8	0.0
Exposure to tobacco smoke at home	0.2	0.2	1.6	-0.1	-1.0	-0.3	-0.2	-0.1	-0.1	-0.0	0.3	-0.8	-0.2	-1.3	-0.4	-0.5	0.3	-0.2	0.7	-0.2	-0.6	-0.4	-0.6	-0.4	-0.3	-0.6	0.4	-0.1	-0.1
Glaucoma (self-reported)	0.2	0.2	1.1	0.2	0.1	0.1	0.4	1.1	0.5	-0.7	-0.6	0.1	0.7	-0.3	0.3	0.3	-0.6	0.8	0.1	0.4	0.2	0.2	-0.1	0.2	0.2	-0.8	0.0	0.0	-0.1
High blood pressure (siblings)	0.2	0.2	1.1	-0.3	0.2	-0.8	0.1	0.6	-0.3	-0.0	-0.3	-0.2	-0.0	-0.3	0.1	1.0	-0.6	-0.4	-1.0	-0.0	-0.3	0.1	-0.4	-0.2	-0.2	-0.4	-0.9	-0.5	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.3	1.8	0.4	0.3	-0.4	0.2	-0.1	0.3	0.1	-0.2	0.3	-0.9	0.2	-0.1	0.2	1.3	-1.4	0.0	0.4	0.3	0.3	0.4	-0.2	0.7	0.9	0.3	-0.0	-0.2
Angina (self-reported)	0.2	0.3	1.5	-0.1	-0.8	1.1	-0.5	0.8	-0.6	0.4	0.7	-0.1	0.4	0.2	0.1	0.1	1.2	-0.1	0.6	-0.3	-0.3	-0.2	0.2	0.1	0.1	1.2	0.9	0.3	0.3
Medication: Aspirin	0.2	0.3	2.0	0.5	0.1	1.4	0.3	0.8	0.1	-0.3	0.1	0.3	-0.1	0.2	0.8	-0.5	0.9	0.3	0.1	0.4	0.3	0.2	0.6	0.8	0.3	1.3	0.5	0.2	0.1
Supplements: Vitamin C	0.2	0.2	2.2	0.2	0.1	-0.3	0.2	-0.3	-0.0	0.1	0.1	-0.0	-1.2	-0.1	0.0	-1.5	0.0	-0.5	0.5	0.1	0.0	0.2	0.1	-0.0	-0.1	0.3	0.6	0.1	0.5
Handedness (chirality/laterality): Left-handed	0.2	0.2	2.7	0.0	-0.0	-0.4	-0.0	-1.0	-0.4	0.3	0.1	-0.1	-1.6	-0.0	0.0	-0.4	0.1	-0.7	0.3	-0.0	-0.1	-0.2	0.1	0.1	-0.1	0.2	0.0	-0.3	-0.3
Ever had bowel cancer screening	0.2	0.3	1.8	0.5	0.5	-0.1	0.2	0.3	0.2	0.4	-0.3	0.5	-1.0	0.7	0.4	-0.3	1.3	-0.5	0.7	0.2	0.3	0.5	0.6	-0.4	0.6	0.2	0.5	0.7	0.3
Breast cancer (self-reported)	0.2	0.3	2.0	0.2	-0.7	0.1	0.3	1.0	0.6	0.0	-0.1	-0.7	0.1	-1.4	0.4	0.5	-0.3	-0.1	0.0	0.3	-0.2	-0.2	-0.5	-0.1	-0.0	-0.7	-0.6	-0.6	-1.0
Osteoarthritis (self-reported)	0.2	0.2	1.0	-0.1	-0.1	-0.9	-0.1	-0.1	0.2	0.3	0.2	0.4	-1.0	0.7	0.5	-0.3	-0.2	-0.7	0.7	-0.2	0.3	0.2	0.4	0.1	0.0	0.2	0.5	0.7	1.0
Medication: Gliclazide	0.2	0.2	1.4	0.2	0.2	-0.0	-0.2	-0.6	-0.2	-0.2	0.1	0.1	-0.7	0.4	0.0	0.6	1.2	0.3	0.2	-0.1	-0.1	0.1	0.3	0.4	-0.4	1.0	0.5	0.8	0.7
Illnesses of father: None of the above (group 1)	0.2	0.2	1.0	0.0	-0.6	0.2	-0.2	0.6	-0.1	0.0	0.4	-0.7	-0.2	-1.0	0.2	-1.0	0.5	-0.3	0.2	-0.1	-0.5	-0.3	-0.3	-0.1	-0.4	0.3	-0.2	-0.3	-0.7
Smoking status: Current	0.2	0.4	1.8	0.3	0.5	0.9	0.3	0.4	0.1	-0.7	-0.0	0.7	1.4	0.9	0.2	0.3	0.5	1.3	-0.0	0.4	0.5	0.5	0.6	0.7	0.8	0.7	0.1	0.2	-0.1
Mother’s age at death	0.2	0.3	2.4	0.1	0.2	0.1	0.0	-1.1	-0.2	-0.1	-0.0	0.4	-1.6	0.6	-0.1	-0.8	0.3	-0.2	0.5	0.2	0.3	0.1	0.3	0.3	0.5	0.6	1.0	0.3	0.4
Medication: Bendroflumethiazide	0.2	0.3	1.7	-0.1	-0.0	1.1	0.0	1.2	0.0	-0.4	0.2	0.1	1.3	-0.1	0.0	0.1	-0.4	0.9	-0.3	0.1	0.1	-0.0	0.2	0.4	0.3	0.3	-0.2	-0.4	-0.5
Medication: Lisinopril	0.2	0.3	1.5	-0.9	-0.2	-0.9	-0.6	0.1	-0.6	0.4	-0.0	-0.3	-0.3	-0.2	-0.4	-0.1	-1.2	-0.2	-0.8	-0.6	-0.4	-0.5	-0.6	-0.3	-0.3	-1.2	-0.3	-0.7	-0.3
Average weekly beer plus cider intake	0.2	0.2	1.4	-0.2	-0.8	-0.2	-0.4	0.3	-0.3	0.2	0.1	-0.8	0.0	-1.2	-0.1	0.0	-0.0	-0.1	0.7	-0.5	-0.7	-0.5	-0.5	-0.7	-0.7	-0.6	-0.2	0.2	-0.3
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.7	-0.3	-0.3	-0.4	-0.5	-0.7	-0.6	0.6	0.6	-0.2	-0.2	0.0	-0.6	-1.3	0.5	-0.4	0.3	-0.5	-0.5	-0.5	-0.3	-0.6	-0.4	-0.1	0.4	0.3	-0.2
Pain experienced in last month	0.2	0.3	1.4	0.2	-0.1	-0.1	0.3	-0.6	0.0	0.0	-0.1	-0.6	-1.0	-1.2	-0.1	-0.2	-0.1	-0.6	-0.6	0.2	-0.3	-0.2	-0.5	-0.3	-0.1	-0.5	-1.1	-0.8	-1.0
Supplements: Calcium	0.2	0.3	1.3	0.3	0.9	1.1	0.5	0.4	0.0	-0.2	-0.5	0.7	-0.3	0.7	0.3	0.4	-0.1	0.2	0.0	0.6	0.6	0.4	0.6	0.6	0.5	0.1	-0.1	-0.1	-0.6
Schizophrenia vs Biploar Disorder	0.1	0.1	0.5	-0.1	-0.3	-0.0	-0.1	-0.3	0.3	0.0	0.2	-0.3	0.1	-0.5	-0.3	0.4	0.0	0.1	-0.0	-0.1	-0.3	-0.3	-0.4	-0.0	-0.2	0.5	-0.5	-0.7	-0.6
Worry (Nagel 2018)	0.1	0.1	0.4	-0.0	-0.4	-0.6	-0.2	-0.5	0.1	-0.2	0.1	-0.4	-0.2	-0.4	-0.1	-0.6	0.3	0.2	0.4	-0.4	-0.3	-0.3	-0.2	-0.4	-0.6	-0.3	0.1	0.3	0.5
Reaction Time	0.1	0.2	1.3	0.5	0.1	-0.5	0.3	0.6	0.5	0.1	-0.3	0.1	-0.6	-0.2	0.6	0.0	1.0	-0.7	0.2	0.3	0.2	0.5	0.3	0.1	0.2	1.1	0.4	0.1	1.0
Ovarian Cancer	0.1	0.2	1.2	-0.2	0.0	-0.2	0.0	0.2	0.1	-0.5	-0.2	-0.2	-0.2	-0.4	0.0	0.7	-0.4	0.2	-1.1	0.0	-0.1	-0.2	-0.4	0.2	-0.1	0.2	-0.8	-0.5	-0.8
Average weekly spirits intake	0.1	0.1	1.2	0.0	0.2	-0.7	0.2	-0.4	0.1	-0.0	-0.4	0.1	-0.0	0.1	-0.3	0.2	-0.4	-0.2	-0.0	0.1	0.1	0.3	-0.1	-0.3	0.3	-1.1	0.0	-0.1	0.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	1.2	-0.1	0.4	0.3	-0.1	0.0	-0.3	0.2	0.1	0.3	0.1	0.9	0.3	-0.4	0.1	0.1	-0.7	-0.2	0.1	0.2	0.3	0.2	-0.1	1.1	0.2	0.5	0.4
Stomach or abdominal pain in last month	0.1	0.1	0.6	0.1	-0.0	0.1	0.1	0.8	0.3	-0.3	-0.1	-0.1	-0.6	-0.3	0.4	0.3	-0.0	-0.0	-0.5	0.1	0.1	0.2	0.0	0.3	0.1	0.4	-0.3	-0.6	0.2
Past tobacco smoking	0.1	0.2	0.8	-0.1	-0.1	0.1	0.2	0.8	-0.0	-0.0	0.1	-0.3	-0.4	-0.5	0.5	0.4	-0.6	-0.1	-0.5	0.1	-0.1	0.2	-0.1	0.4	-0.3	0.1	-0.9	-0.8	-0.2
Worrier / anxious feelings	0.1	0.3	1.5	-0.3	0.0	0.1	-0.3	0.2	-0.1	0.1	0.2	0.3	1.2	0.7	-0.4	-0.9	-0.6	0.6	0.0	-0.3	0.0	0.0	0.1	-0.4	-0.2	-0.5	0.4	0.8	1.1
Pulse rate	0.1	0.1	0.8	-0.1	-0.1	-0.5	0.2	0.9	0.1	-0.1	-0.3	-0.3	-0.1	-0.7	0.3	0.4	-0.3	0.4	0.4	0.3	-0.2	0.1	-0.3	-0.1	0.2	-0.6	0.4	-0.2	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.8	0.0	0.2	0.7	0.1	-0.3	0.3	-0.4	0.2	0.3	0.0	0.7	0.0	-0.4	-0.4	0.3	-0.9	0.2	0.3	0.1	0.2	0.5	0.2	0.4	-0.3	0.2	0.0
Had major operations	0.1	0.1	0.9	-0.3	-0.4	-0.0	-0.5	0.2	-0.4	0.3	0.6	-0.2	0.2	0.0	-0.4	-1.0	0.4	-0.0	-0.1	-0.5	-0.3	-0.5	-0.1	-0.5	-0.3	0.2	0.2	0.3	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	1.2	-0.2	0.6	-0.6	0.0	0.3	-0.1	-0.0	-0.1	0.7	-0.4	1.1	0.2	-0.0	-0.5	0.5	-0.6	0.2	0.4	0.2	0.3	0.3	0.6	-0.2	0.1	0.2	0.2
Medication for cholesterol	0.1	0.1	0.6	0.4	0.0	0.4	0.1	-0.5	0.3	-0.1	0.1	0.1	-0.6	0.1	0.4	-0.1	0.8	-0.2	0.0	-0.0	0.1	0.1	0.3	0.1	-0.2	0.7	-0.2	0.2	0.0
Osteoporosis (self-reported)	0.1	0.1	0.6	0.1	0.2	-0.1	0.2	-0.3	-0.0	-0.2	-0.2	-0.3	0.1	-0.5	-0.1	0.6	-0.2	0.5	-0.0	0.1	-0.1	-0.2	-0.3	0.0	-0.7	-0.4	-0.7	-0.5	-0.7
Medication: Aspirin	0.1	0.2	1.4	0.4	-0.3	1.2	0.2	0.7	-0.0	-0.4	0.2	-0.1	-0.1	-0.3	0.6	-0.6	0.7	0.2	0.2	0.2	-0.0	0.0	0.2	0.5	0.0	0.9	0.4	0.1	-0.1
Number of self-reported non-cancer illnesses	0.1	0.2	2.3	-0.5	0.0	0.0	-0.2	0.7	-0.0	0.1	0.2	0.0	1.5	0.1	-0.2	-0.6	-1.1	0.8	-0.4	-0.2	-0.1	-0.1	-0.3	0.1	-0.1	-0.0	0.3	-0.0	0.1
Miserableness	0.1	0.3	1.3	0.2	0.2	0.6	-0.1	0.3	0.2	-0.5	-0.0	0.3	0.3	0.5	0.2	0.1	0.4	0.9	0.8	-0.1	0.3	-0.0	0.6	0.4	-0.1	0.3	1.0	0.8	1.1
Wears glasses or contact lenses	0.1	0.1	1.4	-0.0	-0.1	-0.5	0.0	-0.4	-0.1	0.4	-0.1	-0.0	-0.4	-0.2	-0.1	-0.4	-0.2	-0.3	0.1	0.0	0.0	-0.1	-0.1	-0.3	-0.0	-1.2	0.3	0.1	-0.0
Ever taken oral contraceptive pill	0.1	0.1	1.0	-0.1	-0.4	0.1	-0.1	-0.6	-0.1	0.4	0.1	-0.1	-0.6	-0.3	-0.3	0.1	-0.0	-0.6	-0.3	-0.1	-0.1	-0.2	-0.3	-0.4	0.0	-1.0	0.1	0.1	-0.6
Hair Pigment	0.0	0.9	2.1	-1.0	-0.9	-1.3	-1.2	-0.9	-1.3	1.0	1.0	-1.0	-1.4	-0.3	-1.2	-0.6	0.4	-1.5	-0.6	-1.4	-1.1	-0.9	-0.7	-1.3	-0.6	-0.4	-0.2	-0.0	-0.1
Tanning	0.0	0.3	1.8	0.3	-0.3	-0.3	0.0	-0.5	0.2	-0.2	-0.2	-0.3	0.1	-0.3	0.1	-0.9	0.9	-0.0	1.3	-0.0	-0.1	-0.1	-0.1	-0.3	-0.5	-0.3	1.2	1.3	0.8

Hub : Genes

CSPG4P11

Models

Trait associations