TWAS hub - UBE2Q2P1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0780	0.0280	7.0e-05	0.043	0.046	0.040	NA	0.040	5.9e-06	2.3e-06	1.0e-05	NA	9.9e-06
2	GTEx	Adipose Subcutaneous	0.2360	0.0690	1.2e-04	0.047	NA	0.095	NA	0.084	9.6e-05	NA	3.3e-08	NA	2.2e-07
3	GTEx	Adipose Visceral Omentum	0.1410	0.0570	1.7e-03	0.028	NA	0.062	NA	0.042	1.3e-02	NA	4.0e-04	NA	3.1e-03
4	GTEx	Artery Aorta	0.1510	0.0570	8.4e-05	0.005	NA	0.051	NA	0.032	1.7e-01	NA	8.4e-04	NA	6.6e-03
5	GTEx	Brain Cerebellar Hemisphere	0.1790	0.0720	2.9e-03	0.079	NA	0.125	NA	0.099	4.6e-03	NA	4.2e-04	NA	1.7e-03
6	GTEx	Brain Cerebellum	0.3000	0.0960	1.1e-04	0.013	NA	0.060	NA	0.049	1.3e-01	NA	7.5e-03	NA	1.4e-02
7	GTEx	Breast Mammary Tissue	0.0820	0.0360	1.8e-03	0.018	NA	0.028	NA	0.022	3.9e-02	NA	1.4e-02	NA	2.6e-02
8	GTEx	Breast Mammary Tissue (Male)	0.0101	0.0380	4.2e-01	0.004	NA	-0.013	NA	0.011	2.5e-01	NA	8.5e-01	NA	1.7e-01
9	GTEx	Breast Mammary Tissue (Female)	0.1783	0.1003	1.1e-02	-0.010	NA	0.018	NA	-0.006	8.5e-01	NA	9.5e-02	NA	5.1e-01
10	GTEx	Colon Transverse	0.1010	0.0440	2.2e-03	0.016	NA	0.002	NA	-0.002	5.6e-02	NA	2.6e-01	NA	4.1e-01
11	GTEx	Esophagus Mucosa	0.3840	0.0620	2.2e-16	0.262	NA	0.283	NA	0.276	1.2e-17	NA	3.7e-19	NA	1.2e-18
12	GTEx	Esophagus Muscularis	0.3360	0.0740	1.6e-06	0.033	NA	0.118	NA	0.151	4.0e-03	NA	1.3e-07	NA	1.9e-09
13	GTEx	Lung	0.0949	0.0394	1.7e-03	0.001	NA	0.040	NA	0.005	2.7e-01	NA	4.5e-04	NA	1.2e-01
14	GTEx	Nerve Tibial	0.1271	0.0673	2.3e-03	0.010	NA	0.036	NA	0.005	6.2e-02	NA	1.3e-03	NA	1.4e-01
15	GTEx	Pituitary	0.3240	0.1140	7.7e-04	0.005	NA	0.039	NA	0.064	2.4e-01	NA	3.7e-02	NA	1.1e-02
16	TCGA	Brain Lower Grade Glioma	0.0740	0.0316	1.1e-06	0.037	0.061	0.051	NA	0.054	4.1e-05	1.8e-07	1.9e-06	NA	8.6e-07
17	TCGA	Liver Hepatocellular Carcinoma	0.1020	0.0550	5.9e-03	0.003	0.027	0.006	NA	0.005	2.3e-01	1.9e-02	1.7e-01	NA	1.8e-01
18	TCGA	Lung Squamous Cell Carcinoma	0.0346	0.0213	4.8e-03	0.030	0.016	0.016	NA	0.024	2.4e-04	5.4e-03	5.9e-03	NA	9.2e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	10	11	12	13	14	15	16	17	18
Impedance of leg (right)	10.8	52.1	132.2	5.5	1.6	6.4	9.1	11.5	1.8	5.8	6.9	8.6	7.6	-0.4	7.1	10.7	9.4	9.2	9.6
Impedance of leg (left)	10.0	48.4	127.7	5.0	1.4	6.0	8.8	11.3	1.9	5.9	6.9	8.4	7.4	-0.8	7.1	10.2	9.0	8.5	9.2
Impedance of whole body	9.8	49.9	153.8	5.3	1.3	5.7	8.9	12.4	2.6	6.1	6.9	8.3	6.6	-0.5	6.8	10.5	9.1	8.4	9.5
Forced expiratory volume in 1-second (FEV1), predicted	9.2	19.1	40.9	3.8	2.4	2.8	5.4	5.9	4.7	3.2	4.0	6.4	2.0	1.0	4.8	5.0	6.0	5.7	6.4
Standing height	8.0	78.9	205.2	7.8	3.7	5.3	10.3	14.3	7.6	6.1	8.2	12.6	5.4	3.2	10.5	9.0	11.5	11.6	13.6
Trunk fat percentage	7.7	30.7	57.6	5.8	2.1	5.5	7.2	7.1	-0.1	4.7	4.4	6.3	7.6	1.2	6.3	7.1	6.9	7.3	7.2
Impedance of arm (left)	7.6	35.1	121.0	4.5	0.8	4.5	7.2	11.0	2.8	5.0	5.5	7.1	4.5	-0.4	5.2	9.1	7.5	7.0	8.3
Comparative height size at age 10	7.6	42.1	132.2	4.6	1.2	3.7	7.1	11.5	5.5	5.4	6.0	9.6	2.7	1.1	7.1	6.8	8.1	8.2	10.6
Impedance of arm (right)	7.4	34.3	116.6	4.7	1.1	4.7	7.3	10.8	2.4	4.8	5.1	6.7	4.7	-0.1	5.1	9.4	7.3	7.0	7.9
Bipolar Disorder or Schizophrenia	7.2	17.6	55.3	-2.5	-2.0	-0.8	-4.2	-5.4	-4.7	-3.4	-5.4	-7.1	0.1	-1.1	-2.9	-3.4	-6.2	-5.6	-7.4
Height	6.7	129.8	353.4	9.0	4.3	6.5	13.5	18.8	9.2	7.6	9.5	17.3	6.0	3.5	14.2	11.2	14.4	15.0	17.9
Trunk fat mass	6.6	28.4	53.0	5.7	2.4	5.1	6.7	6.7	0.5	4.2	4.3	6.4	7.0	1.7	6.5	6.1	6.7	7.3	7.3
Body fat percentage	5.6	22.1	52.6	5.1	1.8	5.2	6.2	5.5	-1.0	4.0	3.5	4.9	7.2	0.9	5.5	6.0	5.6	6.1	5.7
Lung FEV1/FVC ratio	5.4	27.4	59.9	6.0	2.8	1.2	6.9	3.5	1.5	3.6	3.4	7.7	7.1	4.0	7.3	5.9	6.9	7.5	6.5
Schizophrenia (2018)	5.1	10.6	35.9	-1.4	-1.1	-0.7	-2.5	-4.7	-3.6	-2.9	-4.3	-5.4	-0.3	-0.4	-1.8	-2.6	-4.8	-4.5	-6.0
Forced expiratory volume in 1-second (FEV1), Best measure	5.1	16.2	35.2	3.4	1.6	2.1	4.5	5.9	4.3	4.0	3.1	5.8	2.3	0.5	5.5	4.3	4.9	5.1	5.8
Whole body fat mass	4.7	19.4	40.3	4.9	2.2	4.7	5.7	4.8	-0.3	3.5	3.3	5.0	6.3	1.6	5.6	4.9	5.4	6.1	5.7
Bipolar Disorder (2018)	4.6	7.3	20.7	-2.2	-2.1	-0.1	-3.6	-2.8	-3.1	-1.8	-3.2	-4.5	0.5	-1.3	-2.4	-2.2	-3.8	-3.5	-4.4
Forced expiratory volume in 1-second (FEV1)	4.3	14.4	36.6	3.1	1.2	1.3	4.3	5.5	4.1	3.9	3.4	6.0	1.9	-0.3	5.0	4.0	4.5	4.4	5.7
Sitting height	4.2	29.8	58.1	4.4	4.2	5.0	6.3	7.2	4.5	4.4	6.2	6.4	4.2	2.3	7.0	5.2	7.2	7.4	7.6
Schizophrenia (2014)	4.1	9.1	32.8	-1.1	-1.0	-0.8	-2.4	-4.0	-3.6	-2.6	-4.0	-5.5	-0.0	-0.4	-1.7	-1.6	-4.5	-3.9	-5.7
Leg fat percentage (right)	3.9	14.2	48.4	4.1	1.7	5.0	4.7	3.1	-2.3	3.2	2.4	3.2	7.0	0.5	4.6	4.8	4.1	4.8	3.8
Waist Hip Ratio (WHR)	3.5	15.6	54.5	-0.3	4.5	1.8	4.1	5.4	4.5	0.8	4.3	7.4	1.1	-0.5	5.6	3.0	5.2	4.5	5.3
Number of children fathered	3.5	4.0	8.9	-2.5	-1.0	-1.6	-2.1	-1.8	-1.3	-2.0	-1.2	-1.9	-1.6	-1.5	-2.3	-3.0	-3.0	-2.9	-2.5
Leg fat percentage (left)	3.3	11.8	45.2	3.7	1.4	4.6	4.3	2.7	-2.3	3.1	2.2	2.8	6.7	0.3	4.4	4.2	3.6	4.2	3.2
Leg fat mass (right)	3.2	12.3	35.8	4.1	2.1	4.1	4.5	2.9	-0.9	2.7	2.4	3.5	6.0	1.4	4.5	3.7	4.1	4.9	4.0
Number of full sisters	3.2	3.9	8.1	-1.3	-1.7	-2.2	-1.7	-2.6	-1.7	-2.5	-2.8	-2.4	-1.5	-0.0	-2.2	-0.5	-2.8	-2.3	-2.8
Fluid intelligence score	3.1	6.5	14.7	1.6	2.9	3.7	3.5	2.8	0.6	1.8	3.1	2.5	2.8	1.0	3.8	2.0	3.0	3.1	2.3
Forced vital capacity (FVC), Best measure	3.1	11.2	35.6	2.2	1.3	2.4	3.3	6.0	4.4	3.6	3.0	4.6	1.0	-0.5	4.4	3.3	3.7	3.5	4.9
Hypothyroidism (self reported)	3.0	7.0	14.7	2.0	2.9	2.2	2.9	2.5	1.7	2.9	2.6	3.5	3.1	2.2	3.1	1.0	3.8	3.7	3.0
Leg fat mass (left)	2.9	11.4	35.0	4.0	2.0	3.9	4.4	2.6	-0.9	2.7	2.2	3.4	5.9	1.3	4.5	3.5	3.9	4.6	3.8
Mouth/teeth dental problems: Dentures	2.8	4.7	9.7	-1.9	-2.2	-1.9	-2.2	-2.7	-1.2	-1.5	-3.0	-2.6	-2.4	-0.3	-2.3	-1.8	-3.1	-3.1	-2.7
Bipolar Disorder (2011)	2.6	2.5	10.4	-0.4	0.4	-0.1	-0.7	-2.8	-1.6	-1.5	-2.6	-2.4	-0.1	1.2	-0.8	-0.1	-2.1	-1.6	-3.2
Weight	2.6	13.0	26.2	4.3	2.3	3.2	4.5	3.7	1.0	2.9	2.5	4.6	4.5	2.1	5.1	2.9	4.4	5.1	4.9
Hip circumference	2.5	10.6	27.3	4.3	1.0	3.0	3.9	3.3	-0.9	2.9	1.9	3.2	5.2	1.5	3.9	3.8	3.7	4.9	4.2
Forced vital capacity (FVC)	2.4	9.4	27.6	1.8	0.9	1.6	2.9	5.3	4.2	3.5	3.1	4.7	0.6	-1.2	4.0	2.6	3.2	2.8	4.6
Allergy	2.4	5.4	17.0	1.5	2.6	2.1	2.4	2.4	1.4	2.7	2.4	3.4	1.9	1.9	4.1	1.7	2.5	2.7	2.3
Ever had hysterectomy (womb removed)	2.3	2.6	10.2	1.7	2.2	2.2	1.6	1.3	-0.0	1.6	1.4	1.1	3.2	1.1	2.2	0.2	1.9	2.1	0.7
Diastolic blood pressure, automated reading	2.3	7.2	18.1	3.7	3.5	4.2	2.3	1.7	1.9	3.2	1.6	2.2	3.0	2.9	3.5	0.6	3.1	3.5	2.0
Waist circumference	2.2	8.0	17.0	2.7	2.0	2.4	3.7	2.6	0.0	1.8	1.9	3.9	4.1	0.7	4.0	3.0	3.5	4.1	3.6
Number of incorrect matches in round	2.2	3.7	7.5	-2.3	-2.0	-2.2	-1.7	-2.4	-2.3	-0.7	-1.3	-2.1	-1.6	-1.3	-2.5	-1.2	-2.7	-2.7	-2.2
Tense / ‘highly strung’	2.2	3.6	6.9	-1.4	-1.6	-2.0	-1.9	-2.5	-2.0	-2.6	-2.0	-1.9	-1.6	-0.9	-2.6	-1.6	-2.5	-2.2	-1.9
Had menopause	2.1	2.6	12.6	-0.5	-1.4	-0.3	-1.4	-1.5	-3.5	-2.3	-2.1	-1.4	1.3	0.4	-1.0	-1.0	-2.1	-1.6	-2.3
Breastfed as a baby	2.1	2.6	9.4	-1.3	-3.1	-2.2	-2.2	-0.3	-1.8	-2.2	-0.9	-1.3	-0.1	-1.3	-2.3	-0.6	-1.7	-1.8	-1.4
Age at first live birth	2.1	3.7	9.5	0.4	1.6	1.4	1.7	3.1	2.4	1.3	2.5	2.0	1.1	0.1	2.0	3.0	2.5	2.3	2.6
Mean Putamen Volume	2.0	2.3	7.8	0.4	-1.2	-1.2	-1.1	-1.4	-1.5	-1.4	-2.1	-2.8	0.5	-0.1	-1.0	-1.1	-2.4	-2.2	-2.1
Frequency of depressed mood in last 2 weeks	2.0	2.8	5.2	1.6	2.0	1.6	1.6	1.5	1.7	1.5	1.7	2.0	1.6	2.1	2.2	0.9	2.3	1.8	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	5.3	2.1	2.2	2.3	1.9	1.3	1.1	1.6	1.5	1.5	2.1	1.4	1.6	1.3	2.1	1.9	1.4
Hypothyroidism/myxoedema (self-reported)	2.0	3.9	11.7	1.4	1.5	1.3	2.0	2.4	1.3	2.2	2.0	3.4	1.9	1.0	2.1	0.6	3.0	2.7	2.7
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.7	11.3	-2.3	-1.0	-1.5	-2.0	-1.5	-1.7	-1.1	-0.7	-1.4	-1.8	-0.7	-1.4	-3.4	-1.8	-2.2	-1.2
Verbal and Numeric Reasoning (VNR)	1.9	4.5	9.5	2.0	1.2	2.9	2.8	2.7	0.5	0.7	2.4	2.1	3.1	0.6	2.8	1.7	2.8	2.9	2.2
Relative age of first facial hair	1.9	3.9	10.0	3.2	1.1	2.3	2.6	2.2	2.0	2.2	0.8	2.0	0.9	1.5	2.5	0.2	2.5	2.5	2.6
Pack years adult smoking proportion	1.9	2.9	11.6	0.6	1.9	1.2	3.4	1.2	0.9	-0.1	1.9	2.4	1.2	2.0	2.0	-0.0	2.1	2.5	1.9
Relative age voice broke	1.9	2.8	8.9	3.0	0.7	1.9	2.3	1.0	-0.2	1.0	-0.0	1.1	2.7	1.2	2.0	1.8	2.2	2.4	1.5
Worry too long after embarrassment	1.9	3.2	8.3	1.5	0.4	0.8	1.5	2.9	1.5	1.5	2.9	1.9	0.9	-0.3	0.8	2.4	2.5	2.4	2.8
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.1	5.7	-1.2	-2.0	-0.9	-2.2	-0.1	-0.1	-0.6	-1.6	-1.7	-2.4	-0.9	-2.2	-0.1	-2.0	-1.8	-1.3
Fed-up feelings	1.8	3.3	6.2	2.1	1.9	1.8	1.8	1.8	2.1	2.2	2.1	2.5	1.5	0.4	2.1	-0.2	2.4	1.9	2.4
Illnesses of father: High blood pressure	1.8	2.3	5.6	0.9	1.2	0.6	1.4	1.2	2.4	2.0	1.8	1.2	1.6	0.1	1.8	1.8	2.1	2.1	1.6
Pulse wave Arterial Stiffness index	1.7	2.0	6.0	0.6	1.4	1.6	1.7	1.7	0.9	0.1	1.2	2.1	0.0	0.9	1.4	0.9	1.9	2.4	2.3
Pulse rate, automated reading	1.7	5.4	21.3	-1.1	-1.4	-0.0	-1.3	-2.7	-4.6	-3.1	-1.9	-3.6	1.1	-0.3	-3.1	-1.0	-2.6	-2.3	-3.6
Arm fat mass (left)	1.7	6.8	19.3	3.3	1.9	3.2	3.5	1.5	-0.9	2.4	1.5	2.6	4.4	1.4	3.5	2.2	2.8	3.6	2.9
Irritability	1.7	2.9	8.1	0.8	1.2	1.8	1.7	1.7	1.3	0.7	2.1	2.4	0.5	1.9	1.3	1.1	2.8	2.7	2.6
Pack years of smoking	1.7	2.5	9.5	0.4	1.6	1.1	3.1	1.3	0.5	0.1	2.1	2.3	1.3	1.8	1.7	-0.0	2.0	2.2	1.9
Hearing difficulty/problems: Yes	1.6	2.5	8.5	-0.5	-1.9	-2.1	-1.2	-1.5	-2.9	-2.2	-1.3	-1.5	1.9	-1.5	-1.8	-0.3	-1.4	-1.4	-1.4
Age when periods started (menarche)	1.6	4.0	14.1	-3.8	-1.1	-1.7	-2.6	-1.1	-2.2	-2.8	-0.9	-2.5	0.0	-1.3	-1.6	-1.1	-2.4	-2.6	-2.7
Hair/balding pattern: Pattern 3	1.6	2.4	5.7	-1.9	-0.2	0.3	-1.6	-1.6	-1.9	-2.4	-1.7	-1.9	-1.8	0.1	-1.6	-1.0	-1.9	-1.7	-2.3
Chronic bronchitis/emphysema (mother)	1.6	1.9	5.8	-2.4	-0.8	-2.4	-1.2	-1.0	-0.2	-1.4	-0.3	-0.4	-0.9	-1.3	-1.6	-1.8	-1.5	-2.0	-1.6
Emphysema/chronic bronchitis	1.6	1.8	3.8	-1.1	-0.9	-0.5	-1.3	-0.7	-1.0	-1.6	-1.5	-1.9	-1.2	-2.0	-1.6	-1.0	-1.9	-1.9	-1.5
Arm fat percentage (left)	1.6	6.3	21.3	3.1	1.2	3.3	3.3	1.8	-1.6	2.2	1.3	2.1	4.6	0.7	2.8	2.9	2.7	3.3	2.6
Average weekly champagne plus white wine intake	1.6	2.1	7.5	1.0	0.3	0.6	1.4	2.0	1.6	2.4	2.0	1.1	0.7	1.0	1.3	2.7	1.7	1.2	1.6
Alzheimer’s Disease (including proxy)	1.5	2.2	7.7	-0.9	-0.6	-1.7	-1.3	-2.4	-2.2	-1.8	-1.2	-1.3	-0.9	0.3	-2.0	-2.8	-1.3	-1.0	-1.5
Blood Eosinophil Count	1.5	11.4	30.9	-5.6	-3.0	-4.5	-3.0	-2.8	-4.9	-3.1	-1.5	-3.3	0.9	-2.6	-4.0	-1.8	-4.2	-4.4	-4.2
Respiratory disease	1.5	3.4	12.9	-1.4	-1.4	-0.1	-2.0	-2.1	-2.4	-1.8	-1.5	-2.5	-1.4	-1.9	-3.6	-1.3	-1.8	-1.8	-1.8
Serious illness, injury or assault to yourself	1.5	1.8	6.6	2.4	0.8	0.6	1.6	0.9	0.4	0.8	0.1	0.8	2.1	1.2	1.4	2.6	1.7	1.5	1.1
Arm fat percentage (right)	1.5	6.0	21.7	3.1	1.4	3.4	3.1	1.5	-1.8	2.3	1.1	1.8	4.7	0.7	2.8	2.9	2.4	3.1	2.3
Number of live births	1.5	2.1	5.2	-2.0	-0.6	-0.4	-1.4	-1.1	-1.7	-1.9	-1.0	-2.0	-0.9	-1.3	-1.1	-1.2	-2.2	-2.3	-2.1
Arm fat mass (right)	1.5	6.1	19.7	3.2	1.9	3.1	3.1	1.4	-1.1	2.3	1.3	2.3	4.4	1.3	3.4	2.1	2.6	3.4	2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	8.3	-2.1	0.2	-1.4	-0.8	-1.6	-1.8	-2.8	-0.4	-0.9	-0.7	-1.1	-0.8	-2.9	-1.7	-1.8	-1.7
Ever highly irritable/argumentative for 2 days	1.5	1.8	4.9	0.2	1.6	0.1	1.4	1.4	1.1	1.1	1.8	1.7	1.6	1.8	1.4	-0.5	2.2	1.8	1.1
Qualifications: nursing, teaching	1.5	2.4	10.5	0.7	-0.5	1.2	1.2	3.2	1.3	1.2	1.9	2.1	0.4	-0.7	0.8	1.3	2.1	1.7	2.8
Commuting to job workplace: Walk	1.5	1.6	7.2	-0.0	0.1	0.5	-0.5	-0.8	-1.5	-2.0	-1.6	-2.7	0.0	0.9	-0.3	-0.7	-1.7	-1.5	-2.2
Asthma (self-reported)	1.5	2.9	8.2	-0.6	-1.3	0.4	-1.4	-2.6	-1.9	-1.7	-1.7	-2.4	-0.9	-1.6	-2.9	-2.1	-1.9	-1.7	-1.8
Pain type(s) experienced in last month: Hip pain	1.5	1.8	5.2	1.4	1.9	1.4	1.6	1.2	0.3	1.4	0.7	1.4	1.6	2.0	2.3	0.7	1.5	1.6	0.8
HbA1C	1.4	1.5	5.5	0.5	2.0	0.4	0.8	0.7	0.7	1.1	1.3	1.5	1.8	0.8	2.4	0.3	1.6	1.3	1.6
Heel T-Score	1.4	10.9	48.3	-3.4	-1.3	-2.0	-1.2	-4.8	-7.0	-2.1	-2.5	-5.0	-0.1	-0.0	-3.0	-3.1	-4.5	-3.1	-4.8
Cardiovascular Disease	1.4	4.6	17.6	4.2	1.5	2.0	2.0	0.9	2.2	2.7	0.7	1.9	2.2	1.7	2.8	1.5	2.6	2.9	2.3
Ever used hormone-replacement therapy (HRT)	1.4	1.8	6.7	-2.1	-0.1	-1.3	-2.1	-0.8	-2.6	-1.5	-0.8	-1.1	-1.1	0.7	-1.1	-1.6	-1.5	-0.9	-1.3
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	7.0	2.6	0.7	0.4	1.9	1.6	1.3	0.5	1.1	1.8	0.4	2.0	0.5	1.1	2.6	2.1	1.8
Illnesses of father: Heart disease	1.4	1.9	5.6	-1.1	-1.8	-2.4	-1.8	-1.3	0.7	-0.9	-1.1	-0.3	-1.7	-1.9	-1.2	-1.6	-1.6	-1.7	-0.5
Medication: Lisinopril	1.4	1.8	5.1	2.0	1.2	1.1	2.2	0.8	0.7	1.6	1.1	0.5	2.1	0.7	1.7	1.9	1.4	1.4	0.7
Intelligence (Savage-Jansen 2018)	1.3	4.0	9.7	2.1	2.1	2.8	2.9	2.5	0.8	0.6	2.0	1.8	2.3	1.1	3.1	1.0	2.3	2.5	2.1
Allergy or Eczema	1.3	3.5	9.4	-1.2	-1.3	-1.5	-1.9	-2.4	-2.2	-2.6	-2.2	-3.1	-0.4	0.2	-3.1	-0.2	-2.0	-1.5	-2.7
Hayfever, allergic rhinitis or eczema	1.3	2.9	12.5	-1.1	-2.4	-2.0	-2.0	-1.3	-0.8	-1.9	-1.5	-2.4	-1.6	-0.9	-3.5	0.2	-1.4	-1.5	-1.5
Medication: Atenolol	1.3	1.6	8.7	2.0	1.5	0.8	1.0	-1.9	-0.4	-1.3	-1.7	-0.1	1.3	3.0	0.8	0.5	0.4	1.2	-0.8
Asthma	1.3	2.6	6.8	-0.7	-1.2	0.5	-1.2	-2.5	-1.9	-1.6	-1.6	-2.4	-0.9	-1.6	-2.6	-1.9	-1.7	-1.7	-1.7
Vascular/heart problems diagnosed by doctor	1.3	3.7	13.0	-3.6	-1.5	-2.1	-1.8	-0.6	-1.8	-1.3	-0.7	-2.2	-2.3	-2.0	-2.4	-2.0	-2.3	-2.2	-1.9
Blood Platelet Count	1.2	14.4	32.3	-4.0	-3.7	-2.9	-5.2	-2.7	-5.0	-4.0	-3.0	-4.3	-1.7	-2.8	-5.0	-2.5	-4.9	-5.7	-4.4
High blood pressure	1.2	3.3	15.1	3.9	1.1	2.2	1.6	0.2	0.9	1.4	0.1	1.4	2.5	1.9	2.4	2.1	1.9	2.1	1.6
Chronic bronchitis/emphysema (father)	1.2	1.4	4.5	-1.8	0.8	0.5	-1.2	-0.5	-1.0	-1.0	-0.4	-1.9	0.4	-0.1	-1.0	-2.0	-1.4	-1.0	-2.1
Falls in the last year	1.2	1.6	6.4	0.3	0.5	1.4	1.6	1.1	2.0	2.5	1.8	1.6	-0.6	-0.7	0.5	-0.2	1.4	0.7	1.7
Length of working week for main job	1.2	1.4	4.6	-1.1	-0.7	-2.1	-1.3	-1.5	0.1	-0.4	-0.4	-0.2	-1.6	0.1	-2.1	-1.7	-1.1	-1.5	-0.8
Medication: Ventolin 100micrograms inhaler	1.2	1.5	4.5	-1.1	-0.5	-0.3	-0.8	-2.1	-2.1	-0.8	-1.3	-1.6	0.1	-0.8	-1.4	-1.5	-1.3	-1.1	-1.9
Comparative body size at age 10	1.2	3.2	14.7	-2.6	-0.9	-1.0	-2.7	-2.3	-0.6	0.7	0.0	-1.6	-0.9	-1.6	-1.5	-3.8	-1.8	-2.6	-1.6
Wheeze or whistling in the chest in last year	1.2	2.2	5.6	-1.5	-1.0	-0.4	-1.6	-2.2	-2.1	-2.4	-1.5	-1.4	0.0	-1.4	-1.9	-1.3	-1.8	-1.2	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.3	3.2	-1.1	-1.0	-1.6	-1.8	-0.8	-1.3	-0.9	-0.5	-1.3	-0.7	-0.2	-1.1	-1.1	-1.7	-1.8	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	4.4	-0.9	-1.8	-1.5	-1.0	-1.4	-0.0	0.7	-0.6	-0.9	-1.2	-1.8	-2.1	-1.0	-1.2	-1.4	-1.1
Family relationship satisfaction	1.2	1.5	3.6	-1.9	-1.0	-1.5	-1.1	-1.2	-1.9	-1.7	-1.4	-1.0	0.0	0.6	-1.0	-1.7	-1.3	-0.9	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	5.3	-1.4	-0.9	-1.5	-0.8	-1.9	-1.1	-1.4	-0.7	-1.0	0.7	-1.0	-2.3	-0.9	-0.9	-1.4	-1.3
Supplements: Fish oil (including cod liver oil)	1.2	1.6	4.0	0.3	2.0	1.1	1.8	1.8	1.6	1.9	1.6	1.1	-0.2	1.3	1.8	0.2	1.0	0.4	0.5
Ever depressed for a whole week	1.2	1.5	3.9	-0.8	-0.8	-1.5	-1.0	-1.5	-1.7	-1.7	-1.5	-1.0	-0.6	-1.0	-2.0	-0.1	-1.6	-1.4	-1.3
Depression (Nagel 2018)	1.1	1.7	3.6	1.7	1.5	1.6	1.4	0.9	0.9	1.2	1.1	1.2	1.9	1.0	1.6	1.7	1.6	1.2	1.4
Medication: Levothyroxine sodium	1.1	1.8	5.8	0.8	1.5	0.8	1.5	1.2	1.3	1.8	1.1	2.4	1.5	0.7	1.6	0.6	1.9	1.8	1.4
Had other major operations	1.1	1.3	7.4	-0.8	2.7	1.4	1.1	1.1	1.7	0.7	1.2	0.2	0.6	-0.4	2.3	-0.8	0.4	0.1	0.0
Illnesses of mother	1.1	1.3	5.4	0.2	0.2	-0.4	0.5	2.0	2.1	0.3	1.1	1.1	-1.4	0.1	-0.8	0.9	1.6	1.3	2.3
Medication: Blood pressure	1.1	1.9	7.1	2.7	0.1	1.5	1.9	0.6	0.3	0.5	-0.0	1.6	1.9	1.1	1.2	2.0	1.6	1.7	1.4
Commuting to job workplace: Car/motor vehicle	1.1	1.2	4.8	0.0	0.9	1.6	0.2	1.5	1.5	2.2	0.9	1.2	-0.9	-1.3	1.1	-0.7	0.9	0.8	1.2
Average weekly red wine intake	1.1	1.6	4.5	1.9	1.0	1.3	1.0	0.7	-0.9	0.1	1.0	0.9	2.1	1.6	1.2	0.5	1.9	2.1	1.6
Eye problems/disorders: Cataract	1.1	1.3	7.0	-0.3	1.3	1.6	1.5	2.6	1.0	0.2	1.4	0.6	0.5	0.7	1.0	1.2	1.0	0.9	1.0
Unable to work because of sickness or disability	1.1	1.4	5.0	-1.9	-0.3	-0.9	-1.0	-1.2	-1.2	-0.8	-0.5	-0.8	-0.2	-2.1	-0.4	-1.1	-1.6	-2.2	-1.3
Commuting to job workplace: Cycle	1.1	1.4	7.5	-0.4	-1.9	-2.7	-2.0	1.0	1.1	0.5	-0.7	0.6	-1.4	0.1	-1.5	-0.7	-0.6	-1.1	0.2
Triglycerides	1.0	1.7	5.2	1.1	0.9	1.6	1.9	1.2	-0.4	0.1	0.3	0.5	2.2	1.0	1.2	2.0	1.7	2.3	1.0
Angina	1.0	1.3	5.2	-0.2	2.0	0.6	1.1	1.1	2.3	0.5	1.6	1.9	0.4	0.3	1.5	1.0	0.9	0.6	0.7
Multivitamins +/- minerals	1.0	1.3	4.9	-2.2	0.3	0.1	-1.0	-0.2	-1.0	-1.8	-0.3	-1.6	-0.9	0.6	-0.5	-1.7	-1.3	-1.4	-1.4
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	5.1	1.6	1.0	2.3	1.4	0.6	1.1	1.1	0.4	0.7	1.3	0.7	1.2	-0.3	1.3	1.3	1.0
Hair/balding pattern: Pattern 2	1.0	1.2	4.0	-1.6	-0.5	-1.0	-1.7	0.8	2.0	1.8	0.8	-0.3	-1.6	-1.4	-0.3	-1.0	-0.5	-0.9	0.1
Gout (self-reported)	1.0	1.3	4.8	0.8	0.2	-0.4	1.4	2.2	1.3	0.4	0.8	2.0	0.7	0.6	0.5	0.4	1.7	1.5	1.8
Back pain experienced in last month	1.0	1.5	6.6	-0.9	1.3	0.4	1.5	1.7	0.6	-0.2	2.6	1.9	0.2	-0.1	1.5	0.5	1.4	0.7	1.7
Mineral and other dietary supplements	1.0	1.4	5.0	-0.1	-1.4	-1.5	-1.7	-2.2	-0.6	-1.0	-1.8	-1.6	0.3	-1.0	-1.4	-0.7	-1.1	-0.5	-1.0
Tinnitus: Yes, now most or all of the time	1.0	1.2	5.6	0.1	0.1	-0.7	0.5	-0.6	-1.6	-2.4	-1.8	-0.4	0.8	2.4	-0.6	-0.4	-0.5	0.4	-1.0
Medication: Blood pressure	1.0	2.0	8.5	2.0	2.1	2.9	1.2	1.0	0.6	1.2	0.8	0.3	1.4	1.2	2.6	1.1	0.9	1.1	0.4
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	5.1	-1.2	-0.3	-1.2	-0.5	-0.6	0.6	-2.3	0.1	-0.3	-0.1	-2.1	-0.7	-1.9	-1.0	-1.9	-0.4
Heart disease (siblings)	1.0	1.3	5.9	0.3	-1.1	-1.0	-0.0	-2.4	-0.0	0.2	-2.0	0.5	-2.1	-0.9	-0.7	-0.9	-1.5	-1.0	-0.8
Crohns Disease (2017)	0.9	1.9	6.5	-1.6	-1.4	-1.2	-2.2	-0.5	-0.3	0.1	-0.7	-1.8	-1.0	-2.5	-1.4	-0.5	-1.7	-2.3	-1.2
Fasting Glucose	0.9	1.1	5.1	1.5	2.3	1.3	1.4	1.0	0.6	-0.2	-0.5	0.2	0.5	1.8	1.4	0.1	0.4	0.8	0.8
Hand grip strength (left)	0.9	2.3	8.4	-1.8	-1.9	-2.4	-1.4	-0.8	0.3	-1.4	-1.5	-0.3	-1.4	-2.9	-0.8	-1.3	-2.1	-1.9	-0.9
Supplements: Glucosamine	0.9	1.2	6.2	-0.6	0.2	0.0	0.8	2.5	1.6	0.2	1.9	1.1	-1.6	-0.6	0.2	0.1	0.9	0.4	1.7
Heart attack	0.9	1.1	3.4	0.6	1.2	0.9	1.0	0.3	1.2	-0.2	1.5	1.9	1.1	1.0	0.6	0.7	1.8	1.0	1.3
Qualifications: A levels/AS levels or equivalent	0.9	2.1	8.0	1.4	-0.1	1.2	1.3	1.8	1.0	1.0	1.4	1.7	-0.1	0.7	1.1	2.8	2.1	1.9	2.1
Prospective memory result	0.9	1.1	5.4	-0.9	-0.8	-2.3	-2.0	-0.7	-0.1	-0.8	-0.8	-0.7	-0.7	-0.3	-1.8	-0.2	-0.7	-0.9	-0.8
Blood clot in the leg (DVT)	0.9	1.2	3.9	-1.3	-0.2	-1.3	-0.4	-0.8	0.4	-2.0	0.3	-0.3	0.2	-1.9	-0.7	-2.0	-0.9	-1.9	-0.5
Migraine (self-reported)	0.9	1.1	3.6	-0.6	-1.4	-1.2	-1.1	-1.5	-1.9	-0.8	-0.8	0.0	0.2	-1.9	-1.1	-0.9	-0.9	-1.1	-0.5
Mean time to correctly identify matches	0.9	1.8	5.1	-1.2	-1.3	0.6	-1.5	-1.0	-1.9	-0.7	-1.2	-1.7	-1.3	-1.6	-0.8	-0.5	-2.2	-2.0	-1.5
Hypertension (Self-reported)	0.9	2.6	12.7	3.6	0.8	2.2	1.4	0.0	0.8	1.4	-0.1	0.8	2.5	1.4	2.1	2.0	1.5	1.8	1.2
Breast cancer (self-reported)	0.9	1.1	5.5	1.7	1.8	1.3	1.2	-1.1	0.8	0.3	-0.4	0.6	0.6	2.4	1.1	-0.1	0.8	0.9	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	5.5	2.3	-0.2	1.1	1.2	0.9	-0.0	1.4	-0.1	1.1	0.8	0.8	0.3	0.8	1.2	1.3	1.9
Supplements: Calcium	0.9	1.0	2.5	-1.1	-1.5	-1.4	-0.7	0.4	-0.6	-1.6	-0.8	-0.5	-1.3	-0.5	-1.0	1.2	-1.3	-1.2	-0.6
Heart attack/myocardial infarction (self-reported)	0.9	1.2	3.1	0.8	1.1	1.0	1.1	0.5	1.3	0.0	1.5	1.7	1.2	1.0	0.7	0.7	1.8	1.0	1.4
Age at First Birth	0.8	1.1	4.4	-2.1	-0.7	-0.9	-1.9	0.8	1.7	-0.7	0.7	0.8	-1.9	-0.8	-1.2	-0.4	-0.2	-0.4	0.4
HDL Cholesterol	0.8	1.4	4.3	-1.5	-0.5	-1.0	-1.7	-0.8	0.5	-0.5	-0.8	-1.4	-0.6	-1.4	-1.0	-1.3	-1.6	-2.1	-1.6
Blood Red Count	0.8	7.6	26.1	0.7	1.9	1.3	2.3	4.7	2.6	2.0	3.6	5.1	1.5	-0.4	2.5	2.1	3.9	3.4	3.9
Type 2 Diabetes (T2D) (2018)	0.8	1.5	7.5	0.7	-0.8	0.6	0.6	1.8	0.4	1.2	1.8	2.0	0.1	-0.4	0.4	0.2	1.7	1.4	2.7
Chronotype (morning person)	0.8	1.9	10.8	0.6	1.0	0.8	0.4	1.7	1.1	3.3	2.6	1.0	0.4	1.5	0.9	1.5	1.5	0.9	1.0
Medication for hormone replacement therapy	0.8	0.9	5.0	0.8	-1.3	-1.0	-1.0	-1.6	-2.2	-0.5	-0.9	-0.5	0.7	-0.9	-1.4	-0.1	-0.5	-0.5	-0.3
Vitamin and mineral supplements	0.8	1.1	3.7	1.9	0.0	-0.7	0.7	-0.3	1.3	1.4	0.0	1.3	1.1	-0.2	0.5	1.3	1.3	1.8	1.5
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	3.3	0.4	-0.8	-1.5	-1.1	-1.7	-1.2	-0.3	-1.3	-0.9	-0.1	0.1	-1.8	0.5	-0.9	-1.0	-1.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	4.9	-2.0	0.3	-0.3	-1.6	-0.3	0.2	0.1	0.4	-1.2	-2.2	-1.4	-0.7	-1.8	-1.2	-1.2	-0.7
Medication: Amlodipine	0.8	1.1	6.0	2.2	-0.7	0.7	-0.4	-1.5	-0.8	-0.9	-2.5	-0.7	0.7	1.8	-0.1	0.4	-0.4	0.2	-0.5
Number of full brothers	0.8	1.1	4.4	0.5	0.3	0.5	-0.7	-2.1	-0.5	0.4	-1.1	-1.8	0.8	-0.6	-0.4	-0.2	-1.2	-1.4	-2.0
Leg pain on walking	0.8	1.0	4.6	-1.1	-1.4	-2.1	-0.7	0.1	-0.8	-1.1	-1.2	0.3	-0.1	-1.3	-0.7	-1.3	-0.9	-1.0	-0.7
Friendships satisfaction	0.8	1.0	3.3	-0.4	0.9	1.6	0.5	0.7	-1.0	-1.2	0.9	0.9	0.8	0.9	0.5	-0.3	1.6	1.8	1.4
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	4.8	-0.1	-0.8	-2.1	-0.9	-1.1	-0.7	0.1	-1.3	-1.9	0.1	-0.0	-2.2	0.1	-1.2	-1.1	-1.7
Basal metabolic rate	0.8	4.6	11.4	2.8	1.8	0.9	2.1	1.7	2.0	1.1	1.3	3.2	1.5	2.4	3.3	0.4	2.5	3.3	3.4
Fractured/broken bones in last 5 years	0.8	1.0	3.8	0.2	0.8	0.5	0.5	1.5	0.2	0.9	1.4	1.4	2.0	0.9	1.1	0.6	1.1	1.0	0.8
Age started oral contraceptive pill	0.8	1.0	3.1	0.0	-1.2	0.2	-0.8	-0.4	-1.6	-0.0	-1.2	-1.8	0.5	0.5	-1.1	-0.0	-1.4	-1.6	-1.7
Alzheimer’s Disease (in father)	0.7	0.8	3.7	0.2	-0.1	-1.1	-1.2	-1.9	-0.3	-1.0	-1.3	-0.8	-0.2	0.2	-0.8	-0.1	-1.2	-0.8	-1.2
Irritable Bowel Disease (IBD)	0.7	1.7	5.6	-1.7	-2.3	-1.5	-1.7	-0.1	-0.5	-0.0	0.1	-1.5	-0.6	-2.4	-1.8	-0.3	-1.0	-2.1	-0.6
Rheumatoid Arthritis	0.7	0.9	3.6	-0.2	0.9	0.4	0.6	0.3	0.8	1.9	1.8	0.2	1.6	-0.3	1.0	1.0	1.2	1.1	0.9
Medication: Co-codamol	0.7	0.8	3.0	1.5	-0.3	-0.4	0.9	0.7	1.2	1.7	0.8	0.9	-0.7	-0.0	-0.7	0.6	0.9	0.7	1.4
Qualifications: CSEs or equivalent	0.7	0.9	3.1	-0.1	-0.6	-1.6	-0.5	-1.3	0.1	-0.2	-1.8	-0.8	-1.1	-0.3	-0.9	-1.5	-1.1	-1.0	-1.2
Hearing difficulty/problems with background noise	0.7	1.1	3.8	-0.9	-0.3	-0.5	0.1	-0.8	-1.4	-2.0	0.2	-1.5	1.6	-1.2	-1.1	0.4	-1.1	-1.3	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	3.1	1.5	0.7	1.0	1.6	-0.6	-0.7	1.3	0.0	0.2	1.7	1.2	0.8	1.0	1.6	1.8	0.9
Noisy workplace	0.7	0.9	3.4	-0.3	-1.4	-1.1	-0.4	-0.3	-1.1	-1.8	-1.1	-0.7	-0.1	-0.6	-1.8	0.4	-1.0	-0.8	-1.1
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.9	0.6	1.9	0.8	1.2	0.1	2.0	1.0	0.9	0.7	0.6	0.2	1.3	0.7	0.8	0.5	0.3
Angina (self-reported)	0.7	0.9	4.4	-0.4	1.7	0.1	0.8	0.9	2.1	0.3	1.3	1.6	0.3	0.0	1.2	0.7	0.5	0.2	0.3
Medication: Ibuprofen	0.7	0.8	4.1	-1.6	-0.3	-2.0	0.0	-0.3	-0.1	-0.4	0.8	-0.2	0.4	-1.7	-0.7	-1.7	0.2	0.1	0.3
Medication: Allopurinol	0.7	1.0	3.2	1.3	-0.5	-1.0	0.8	1.4	1.0	-0.1	0.6	1.7	0.3	0.4	0.2	0.6	1.6	1.1	1.8
Medication: Omeprazole	0.7	0.8	5.5	2.3	-0.9	0.4	0.7	0.1	-1.1	0.2	-0.8	0.4	1.2	1.0	-0.4	0.9	0.5	0.8	1.1
Alcohol intake frequency.	0.7	1.6	5.8	-0.9	0.0	-0.7	-0.7	-2.4	-2.2	-1.1	-1.4	-0.8	1.5	-1.1	-1.0	-1.8	-1.2	-1.2	-1.7
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.8	-1.0	-0.0	0.6	-1.4	-0.2	-0.2	-1.7	-0.1	-1.5	-1.0	0.4	-0.6	-1.4	-0.8	-0.8	-0.9
Alzheimer’s Disease (in mother)	0.6	0.6	2.8	-0.2	-0.9	-0.8	-0.1	-0.5	-1.7	-1.0	-0.4	-0.4	-1.0	0.4	-1.7	-1.3	-0.3	-0.1	-0.4
Coronary Artery Disease (CAD)	0.6	0.7	3.2	-1.6	-0.4	-0.4	-1.1	0.2	1.2	0.1	-0.3	-1.0	-1.1	-1.8	-0.4	-0.7	-0.6	-1.1	-0.3
Systolic Blood Pressure	0.6	3.2	12.7	3.6	2.0	1.9	1.4	0.6	2.6	1.4	-0.9	1.2	1.4	1.6	3.5	0.6	1.5	1.9	0.7
Diabetes (father)	0.6	0.7	3.1	0.0	-0.1	0.3	0.1	0.3	0.3	0.8	1.6	0.7	0.2	0.1	0.6	1.4	1.4	1.3	1.7
Diabetes (mother)	0.6	0.8	1.9	-1.1	0.4	-0.4	-0.0	-1.2	-0.9	-1.0	-0.7	-1.4	-0.6	-1.2	0.1	-0.9	-1.3	-1.3	-1.2
Hand grip strength (right)	0.6	1.6	9.7	-1.8	-1.3	-1.0	-1.3	0.2	1.6	-1.4	-0.0	1.1	-1.2	-3.1	0.4	-0.7	-1.0	-1.4	0.3
Mouth/teeth dental problems	0.6	0.9	3.4	0.5	-0.2	0.7	0.6	1.8	-0.1	0.3	1.5	1.5	0.2	-0.3	0.4	0.6	1.4	1.4	1.8
Pain all over the body in last month	0.6	0.6	5.4	-1.0	-0.2	-0.4	-0.8	-0.9	1.1	0.6	0.5	-0.1	-0.5	-2.3	0.1	-0.3	-0.4	-0.7	0.1
Medication: Cholesterol lowering	0.6	0.9	6.1	0.9	-1.0	-1.6	1.4	-0.3	-0.6	-0.9	-0.2	0.6	2.5	0.7	-0.6	1.1	0.7	0.4	0.1
Birth weight of first child	0.6	1.1	5.1	1.6	-2.2	-0.9	0.0	0.2	-2.1	-0.9	-1.0	-0.1	1.4	0.1	-1.8	0.5	-0.0	-0.1	0.4
Peak expiratory flow (PEF)	0.6	1.4	5.3	-0.1	-1.2	-1.6	0.5	1.3	2.3	1.0	0.4	2.0	-1.3	-1.4	0.5	1.0	0.4	0.2	1.7
High blood pressure (siblings)	0.6	0.8	5.0	1.5	0.3	1.7	0.3	-0.9	-0.7	2.2	-0.7	-0.0	0.8	-0.1	0.8	0.8	-0.1	0.5	-0.2
Arm fat-free mass (right)	0.6	2.8	8.4	2.0	1.1	0.4	1.4	1.1	1.6	0.3	1.1	2.8	1.2	1.9	2.6	-0.3	2.0	2.6	2.9
Neck or shoulder pain in last month	0.6	0.9	2.8	-1.4	-0.9	-0.6	0.2	-0.2	-1.2	-1.7	-0.5	-1.1	0.3	-0.7	-0.8	-0.2	-1.5	-1.5	-1.3
Heart disease (mother)	0.6	0.7	3.3	-0.2	1.5	1.1	0.8	-0.3	-0.5	0.6	0.3	1.3	1.6	0.1	1.8	0.6	0.1	0.2	-0.6
Arm predicted mass (right)	0.6	3.2	8.6	2.1	1.3	0.5	1.6	1.2	1.7	0.4	1.2	2.9	1.4	2.2	2.6	-0.2	2.2	2.8	2.9
Illnesses of siblings: Diabetes	0.6	0.7	3.0	-0.6	0.9	1.7	0.3	0.3	0.7	0.6	1.3	0.8	-0.8	-1.2	1.0	0.7	0.3	0.4	1.0
Medication: Gliclazide	0.6	0.7	2.8	-1.2	-1.4	-1.2	-0.9	0.2	-0.0	0.4	0.8	-0.6	-0.7	-1.7	-1.2	0.0	-0.2	-0.6	-0.2
Arm fat-free mass (left)	0.6	2.8	7.9	2.2	1.4	0.6	1.6	1.0	1.4	0.9	0.9	2.6	1.5	2.1	2.8	-0.3	1.7	2.4	2.5
Risk taking	0.6	0.9	2.3	-0.6	-1.2	-1.3	-1.0	-1.5	-0.3	-0.8	-1.1	-0.4	-1.0	-0.2	-1.0	-0.5	-1.4	-1.4	-1.2
Basal cell carcinoma (self-reported)	0.6	0.8	4.1	-0.2	-2.0	-0.6	0.1	0.9	-0.4	-1.2	-0.7	-0.4	-0.9	-1.3	-1.6	0.6	-0.6	-0.5	-0.1
Body Mass Index (BMI) (2010)	0.5	0.7	3.3	0.6	-0.7	0.7	-0.6	-1.6	-1.3	0.8	-0.6	-1.0	0.5	-0.0	-0.5	-1.8	-0.2	-0.1	-0.5
Ulcerative Colitis	0.5	0.7	2.9	-1.4	-1.2	-1.2	-0.9	0.5	0.1	-0.8	0.3	-0.5	-1.1	-0.9	-1.7	-0.2	-0.3	-0.9	0.1
Lung FVC	0.5	2.7	8.4	-1.1	-2.2	-2.2	-2.4	-0.7	1.6	1.3	-0.7	-0.5	-1.8	-2.9	-0.9	-1.2	-2.2	-2.7	-0.8
Sensitivity / hurt feelings	0.5	0.9	2.6	-1.6	-0.3	0.0	-1.0	0.1	-1.0	-0.0	0.2	-1.6	0.2	-1.4	-0.9	0.5	-1.6	-1.5	-1.4
Supplements: Zinc	0.5	0.5	2.8	1.2	-0.3	1.7	0.4	0.9	0.3	0.4	-0.4	-0.6	0.2	0.7	0.9	1.4	0.1	0.1	0.2
Leg fat-free mass (left)	0.5	2.4	6.6	2.2	1.5	0.2	1.2	0.9	2.0	0.2	0.5	2.2	0.4	2.6	2.0	-0.4	1.6	2.3	2.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	4.6	0.3	0.4	-1.4	0.9	-2.1	-1.3	-1.1	-0.8	-1.2	1.7	1.8	-0.5	-1.2	-0.3	0.3	-1.4
Nervous feelings	0.5	1.0	2.7	-0.7	-0.1	-0.6	-1.1	-1.6	-1.1	-1.3	-0.6	-0.8	-0.9	-0.5	-1.2	-1.6	-1.1	-1.2	-1.1
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	2.5	1.0	-1.0	0.5	0.9	0.7	1.1	0.9	0.2	-0.0	0.7	-0.0	0.1	1.6	1.2	1.0	0.8
Medication: Simvastatin	0.5	0.7	4.4	0.4	0.2	-1.0	0.6	-0.6	-0.8	-1.3	-0.2	0.3	2.1	1.5	-0.5	0.3	0.4	0.5	-0.4
Illnesses of siblings	0.5	0.7	3.8	-0.7	0.1	-1.1	-0.3	2.0	0.4	-1.7	1.0	0.1	0.1	1.4	-0.2	-0.4	0.9	0.2	0.7
Trunk fat-free mass	0.5	2.7	7.4	2.1	1.4	0.1	1.0	1.0	2.2	0.4	0.8	2.5	0.4	2.3	2.5	-0.4	1.7	2.4	2.7
Time employed in main current job	0.5	0.6	2.0	-1.2	0.3	-0.6	1.0	-0.5	-0.1	0.8	0.3	-0.5	-0.1	-1.2	-1.2	0.9	-0.8	-0.8	-1.4
Father’s age at death	0.5	0.7	3.5	-1.9	-0.2	-0.0	-0.6	0.2	-1.5	-1.4	-0.9	-0.2	-0.7	0.0	-0.1	-0.5	-0.7	-0.9	-0.8
Happiness	0.5	0.6	1.7	0.6	-0.2	-0.5	0.7	-0.0	0.2	-1.3	0.3	1.0	0.7	0.9	-0.7	-0.5	1.2	1.3	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	3.3	-1.4	-0.2	-1.8	0.1	0.0	0.6	0.2	0.7	0.2	0.0	-1.4	-0.7	-1.8	0.3	0.3	0.4
Trunk predicted mass	0.5	2.6	7.2	2.1	1.3	0.1	1.0	1.0	2.2	0.3	0.7	2.5	0.3	2.3	2.5	-0.4	1.7	2.4	2.7
Pulse wave peak to peak time	0.5	0.6	1.9	-0.1	-1.0	-1.2	-0.9	-0.7	-0.3	0.4	-0.5	-1.1	0.5	-0.4	-0.6	-0.2	-0.9	-1.4	-1.3
Shortness of breath walking on level ground	0.5	0.6	2.8	1.1	-1.0	0.2	0.4	1.3	0.3	1.0	0.1	1.4	0.5	0.0	-0.2	0.2	0.9	0.6	1.7
Medication: Seretide 50 evohaler	0.5	0.5	1.7	-0.7	0.3	1.1	-0.1	-1.3	-1.3	0.3	0.1	-1.1	-0.4	-0.9	0.1	0.1	-1.0	-0.9	-0.8
Age at last live birth	0.5	0.7	6.6	0.8	-0.4	0.2	-0.1	0.3	0.1	0.3	-0.5	-0.9	1.8	0.6	0.3	2.6	0.2	0.5	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.2	0.8	-1.5	-1.4	0.0	1.0	-0.3	0.1	-0.9	-0.2	-1.5	-0.1	-0.9	-0.2	-0.5	-0.5	0.2
Guilty feelings	0.5	0.8	2.9	-0.3	0.0	-0.6	-0.1	1.1	1.7	0.7	1.4	1.4	-0.5	-1.6	0.6	0.4	0.5	0.3	1.2
Hearing aid user	0.5	0.5	3.0	1.1	0.0	-0.2	0.2	-0.9	-0.6	-0.4	0.2	0.8	1.7	0.7	-0.1	-1.0	0.9	0.9	0.4
Commuting to job workplace: Public transport	0.5	0.6	2.3	-1.2	1.4	-0.5	-0.4	-0.8	-0.4	-1.5	0.7	-0.1	0.9	0.3	1.2	1.0	-0.1	-0.4	-0.5
Medication: Atorvastatin	0.5	0.7	2.1	-0.9	-0.7	-0.7	-0.6	-0.4	-1.0	-1.4	-0.4	-1.0	-0.4	-0.5	-0.7	-0.3	-1.2	-1.4	-1.0
Number of operations (self-reported)	0.5	0.8	2.4	-0.2	1.6	0.9	1.2	1.5	0.6	0.7	1.4	0.8	0.7	0.1	1.0	-0.8	0.9	0.8	0.6
Pain experienced in last month	0.5	0.8	3.2	1.1	-1.0	-0.5	-0.8	0.0	1.8	0.3	-1.5	-0.3	-1.8	0.1	-0.9	-0.8	-0.9	-0.4	-0.2
Alcohol drinker status: Previous	0.5	0.6	5.5	-0.2	-0.9	-0.1	-0.2	-0.2	-2.4	0.1	0.3	1.0	1.4	-0.7	-0.2	-0.2	0.3	0.4	0.7
Arm predicted mass (left)	0.5	2.7	6.4	2.3	1.2	0.3	1.4	0.9	1.3	0.6	0.8	2.5	1.7	2.1	2.5	-0.2	1.8	2.5	2.5
Depressed Affect (Nagel 2018)	0.4	0.8	3.9	-0.7	-0.1	0.5	-0.3	1.3	0.7	1.4	2.0	1.0	0.6	-1.0	0.4	-0.4	0.9	0.3	1.3
Ulcerative Colitis (UC)	0.4	0.8	4.5	-1.1	-2.1	-1.2	-0.5	0.4	-0.8	0.1	0.7	-0.6	-0.1	-1.3	-1.6	-0.4	-0.1	-0.9	0.2
LDL Cholesterol	0.4	0.6	3.4	-0.7	-0.4	1.0	-0.7	0.4	-1.8	-1.8	-0.4	-0.9	0.5	-0.6	-0.2	0.4	0.3	0.7	0.3
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.5	1.1	-0.3	0.9	-0.5	1.0	-0.1	0.8	0.3	0.3	1.2	-0.2	-0.3	0.9	1.0	0.9	0.9
Systolic blood pressure, automated reading	0.4	1.1	3.4	1.8	1.5	1.7	0.4	-0.3	0.3	0.2	-1.4	-0.6	1.0	1.7	1.4	-1.1	-0.1	0.5	-0.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.0	0.7	-1.1	-0.9	-0.6	0.3	0.6	-0.7	-0.1	0.8	-0.6	-1.4	-0.7	-0.8	0.4	-0.0	0.7
Severe depression (siblings)	0.4	0.5	1.4	0.7	-1.1	-0.6	0.4	-1.2	-0.9	0.5	-0.8	-0.7	0.9	1.1	-0.4	-0.5	-0.2	0.0	-0.4
Townsend deprivation index at recruitment	0.4	0.6	3.9	1.3	1.2	0.7	1.0	-2.0	-0.6	-0.2	-0.5	-0.2	0.1	0.8	-0.2	0.4	-0.1	0.2	-0.5
Current tobacco smoking	0.4	0.7	3.1	-0.2	-0.9	-1.1	0.2	-1.8	-0.9	-1.0	-1.2	-0.1	-0.1	-0.2	-1.2	-1.1	-0.9	-0.3	-0.4
Average weekly fortified wine intake	0.4	0.5	1.3	1.1	-1.1	-0.0	0.4	1.0	1.1	1.0	0.3	-0.5	-1.1	0.3	-0.6	-0.5	0.2	0.3	0.5
Maternal smoking around birth	0.4	0.5	3.9	-1.1	0.7	-0.7	0.3	-0.9	1.1	-0.9	0.0	0.7	0.3	-0.1	0.3	-2.0	-0.0	-0.2	-0.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.4	0.4	0.9	1.6	-0.0	-0.4	-1.1	0.1	-0.0	-0.6	1.1	0.1	0.6	-0.9	0.2	0.3	-0.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.8	0.6	0.4	0.3	0.4	1.2	1.4	0.0	1.0	0.7	-0.1	-0.3	0.7	0.3	0.8	0.5	0.8
High blood pressure (mother)	0.4	0.6	2.2	0.3	0.6	0.6	-0.6	-1.3	-0.2	1.1	-0.3	-0.8	1.5	-0.1	1.4	-0.9	-0.5	-0.2	-1.1
Body mass index (BMI)	0.4	1.6	9.0	0.8	0.7	0.8	-0.2	-3.0	-2.5	0.1	-1.2	-1.1	2.2	0.6	0.3	-1.3	-0.8	-0.2	-1.2
Leg predicted mass (left)	0.4	2.4	6.8	2.3	1.5	0.2	1.2	0.8	1.9	0.2	0.5	2.1	0.4	2.6	2.0	-0.5	1.6	2.3	2.4
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	3.5	-0.5	0.1	-1.2	0.5	-1.9	-1.0	-0.8	-0.3	-0.9	1.0	1.2	-0.9	-1.6	-0.4	0.0	-1.0
Alcohol intake versus 10 years previously	0.4	0.6	1.8	-0.7	1.1	-0.4	0.0	-0.1	1.3	1.1	1.3	1.4	0.4	-0.3	0.5	-0.4	0.9	0.5	0.8
Medication: Lansoprazole	0.4	0.4	1.6	-1.3	0.2	0.9	-0.5	1.0	0.8	0.7	0.9	0.2	-0.1	-1.2	0.5	-0.5	0.4	0.4	0.7
Headache pain in last month	0.4	0.6	2.0	0.9	0.4	0.8	1.0	-0.6	-1.4	-0.2	0.4	0.8	1.3	0.0	-0.6	0.7	0.9	1.0	1.0
Glaucoma (self-reported)	0.4	0.5	2.9	0.2	0.8	0.0	0.6	-0.1	-0.9	0.4	0.1	-0.0	1.7	1.5	0.8	0.4	0.5	0.6	-0.3
Exposure to tobacco smoke outside home	0.4	0.6	1.7	-0.4	0.8	0.9	-0.2	1.1	1.3	1.1	0.9	0.5	-0.6	-0.2	0.6	0.9	0.8	0.5	0.8
Qualifications: College or University degree	0.4	1.3	3.9	0.1	0.3	1.8	0.9	2.0	0.9	0.8	1.6	0.9	0.8	-0.1	1.5	1.3	1.4	1.2	1.4
Eye problems/disorders: None of the above	0.4	0.4	1.4	0.3	-0.7	-1.0	-0.0	-1.0	0.2	1.2	0.1	0.9	-0.6	-0.9	-0.1	0.3	0.6	0.5	0.8
Suffer from ‘nerves’	0.4	0.6	1.9	0.7	1.2	0.2	0.9	-0.1	0.1	-0.3	0.5	1.4	0.3	-0.1	0.8	-0.9	1.2	1.1	1.2
Knee pain experienced in last month	0.4	0.6	4.2	0.6	0.0	0.5	0.2	-0.0	-1.8	-0.2	-0.4	-0.5	2.0	1.1	0.7	0.1	0.1	-0.1	-0.8
Whole body fat-free mass	0.4	2.4	6.4	2.0	1.4	0.0	1.0	0.9	2.0	0.2	0.6	2.4	0.3	2.5	2.3	-0.7	1.5	2.3	2.5
Mood swings	0.4	0.6	3.8	-2.0	0.4	-0.7	0.1	-0.6	-1.0	-0.6	1.1	-0.3	1.2	-0.4	-0.6	-1.1	-0.4	-0.7	-0.4
Ever had bowel cancer screening	0.4	0.4	2.2	-0.5	-0.2	0.7	-0.3	0.9	0.2	-0.8	0.0	-0.6	-0.7	-1.5	0.3	0.6	-0.8	-1.0	-0.5
Osteoarthritis (self-reported)	0.4	0.5	2.5	-0.3	1.3	1.6	0.3	-0.3	0.2	0.7	0.8	0.2	0.6	0.3	1.2	-1.1	0.3	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	2.6	1.2	0.1	-0.0	0.8	0.7	0.6	1.2	0.2	1.3	1.6	0.5	1.0	1.3	0.8	1.0	0.8
Whole body water mass	0.4	2.3	6.1	2.0	1.4	0.0	0.9	0.7	2.1	0.2	0.6	2.4	0.3	2.3	2.3	-0.7	1.5	2.2	2.5
Financial situation satisfaction	0.4	0.6	2.5	-0.8	-0.3	-0.2	-0.4	0.2	0.7	-1.6	-0.0	1.1	-1.4	-0.7	-0.6	-0.9	0.3	0.2	1.0
Medication: Paracetamol	0.4	0.6	2.5	-1.6	0.1	-1.2	0.3	0.9	1.1	0.4	1.3	0.1	0.6	-0.8	-0.2	-1.1	0.2	-0.6	-0.1
Average weekly beer plus cider intake	0.4	0.6	4.3	0.2	1.1	0.3	-0.6	0.1	1.5	2.1	0.2	0.4	0.3	0.4	0.8	1.3	0.5	0.4	0.3
Ever had prostate specific antigen (PSA) test	0.4	0.4	2.2	-0.9	-0.4	-0.3	-0.2	1.2	0.2	0.8	1.0	-0.1	-0.3	-0.5	-0.5	-1.5	-0.1	-0.6	0.4
Myopia	0.4	0.6	4.5	0.6	0.1	0.8	0.4	-1.0	-1.1	0.1	0.0	-0.6	2.1	1.2	0.7	-0.0	0.1	0.3	-0.5
Major Depression (MDD)	0.3	0.4	1.5	-1.2	0.9	-0.0	-0.0	-0.7	-0.2	-1.2	-0.0	0.0	0.3	-0.8	0.6	-0.7	-0.4	-0.4	-0.3
Breast Cancer	0.3	0.8	3.3	0.7	-0.5	-0.5	0.9	1.8	-0.2	-0.2	0.3	0.5	-0.3	0.4	-1.2	1.1	1.1	1.7	1.7
Primary Biliary Cirrhosis	0.3	0.4	1.6	-0.4	1.3	1.3	-0.6	-0.1	0.6	0.4	1.0	-0.6	-0.0	-0.6	0.2	-1.1	0.2	-0.2	-0.4
BMI	0.3	2.0	9.1	3.0	0.5	1.1	1.3	-1.4	-1.1	1.9	0.4	0.8	3.0	0.9	1.0	0.2	1.3	1.6	0.9
Medication: Metformin	0.3	0.5	2.1	-0.2	-0.9	-0.1	-0.2	1.5	0.2	0.7	0.5	1.4	-0.2	-0.7	-0.1	-0.6	0.4	0.3	1.1
Alcohol usually taken with meals	0.3	0.4	3.0	0.4	-0.4	0.4	-0.9	-0.3	-0.5	-0.6	-0.8	-0.5	0.3	1.7	-0.2	-1.1	-0.0	-0.0	-0.7
Qualifications: None of the above	0.3	0.7	4.1	-2.0	0.4	-1.1	-0.5	-1.3	0.0	1.1	-0.2	-0.3	-0.6	-1.2	-0.3	-0.9	-1.0	-0.6	-0.6
Medication: Ramipril	0.3	0.4	2.2	1.4	-0.3	0.9	0.3	0.4	0.2	1.0	-0.2	0.2	0.6	-0.0	0.8	1.5	-0.1	-0.1	0.1
Pulse rate	0.3	0.5	2.6	-0.6	0.9	1.6	1.0	0.7	-1.2	0.2	1.3	-0.4	1.0	0.2	-0.2	0.4	0.2	0.5	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.6	0.4	-0.9	-1.3	-0.1	-0.7	0.1	-0.2	-0.8	0.5	0.2	-0.1	-1.0	-0.7	-0.1	-0.2	0.1
Lung cancer (father)	0.3	0.4	1.9	0.5	-0.4	-0.5	-0.2	-1.3	0.5	-0.1	-0.7	-0.7	0.1	0.3	-0.8	-1.4	-0.3	-0.4	-0.6
Hair/balding pattern: Pattern 4	0.3	0.6	4.5	1.0	0.1	0.2	1.3	0.1	-0.8	1.1	0.6	-0.3	2.1	-0.2	0.4	0.7	0.3	0.5	0.8
Birth weight	0.3	0.6	2.2	-1.0	0.1	-1.1	-1.1	-0.4	-1.0	-1.5	-0.1	0.0	0.0	1.4	-1.2	-0.5	-0.5	-0.6	-0.6
Health satisfaction	0.3	0.5	2.7	-0.5	-0.5	-0.8	-0.6	-1.2	-1.2	-0.5	-0.0	0.0	1.6	-0.6	-0.2	-0.4	0.1	-0.3	-0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.9	-0.9	0.7	0.9	-0.1	-0.1	0.2	0.2	0.4	-0.0	0.8	-0.9	0.7	0.4	-0.4	-0.8	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.6	0.5	-0.1	1.2	-1.1	0.5	-0.5	0.8	-0.9	-0.2	0.5	0.7	0.5	-0.5	0.1	0.2	0.1
Leg fat-free mass (right)	0.3	1.5	5.1	1.5	1.4	-0.3	0.5	0.3	2.1	-0.1	0.2	1.7	-0.4	2.2	1.7	-1.3	0.8	1.4	1.7
Long-standing illness, disability or infirmity	0.3	0.5	2.5	0.7	0.2	0.1	0.4	-0.6	-1.6	-1.3	-0.6	-0.3	1.0	0.5	-0.7	0.3	-0.3	-0.3	-0.9
Osteoporosis (self-reported)	0.3	0.4	1.7	-0.8	-1.0	-0.6	-0.8	0.4	0.0	-0.4	-0.7	0.1	-1.3	-0.4	-1.0	-0.1	-0.6	-0.4	-0.4
Smoking status: Current	0.3	0.5	3.5	-0.1	-0.6	-1.0	0.0	-1.9	-0.5	-0.8	-1.0	0.2	-0.0	-0.1	-1.0	-1.0	-0.6	-0.2	-0.2
Leg predicted mass (right)	0.3	1.4	4.9	1.4	1.3	-0.4	0.5	0.3	2.1	-0.0	0.2	1.6	-0.4	2.2	1.6	-1.3	0.8	1.4	1.7
Number of self-reported non-cancer illnesses	0.3	0.5	3.0	1.7	0.1	0.8	0.6	-0.5	-0.2	-0.1	-0.2	0.3	1.7	1.0	0.3	-0.5	0.8	0.2	0.4
Wears glasses or contact lenses	0.3	0.3	1.7	-0.2	0.8	0.5	1.2	0.5	0.4	0.1	1.0	-0.0	0.5	0.0	0.6	-1.3	0.4	0.3	-0.0
Eye problems/disorders: Glaucoma	0.3	0.4	2.2	0.2	0.3	-0.1	-0.1	-0.4	-0.8	0.0	-0.1	-0.8	1.5	1.4	-0.1	-0.1	-0.3	-0.2	-1.0
Alcohol drinker status: Never	0.3	0.4	3.3	-0.9	-0.0	-0.5	-0.3	-0.4	-0.2	0.1	0.5	-0.1	1.0	-1.8	-0.2	-0.5	-0.0	-0.7	-0.7
Ever smoked	0.3	0.5	1.4	0.3	1.0	0.4	0.3	1.1	1.1	0.6	1.2	0.0	0.0	0.3	0.8	-0.3	0.8	0.7	0.8
Cholesterol lowering medication	0.3	0.4	1.2	-0.4	0.7	0.4	-0.5	-0.6	-0.6	-0.7	-0.3	-0.3	-0.1	0.9	0.2	-1.0	-0.8	-0.6	-1.1
Neuroticism (Nagel 2018)	0.2	0.5	3.0	-0.4	-0.2	-0.1	-0.5	0.9	0.8	0.8	1.7	0.7	-0.2	-1.4	-0.3	0.1	0.7	0.1	1.1
Schizophrenia vs Biploar Disorder	0.2	0.3	1.5	0.6	-0.2	-0.1	0.9	0.3	-1.2	-0.6	0.3	-0.6	-0.4	-0.0	-1.2	0.8	-0.0	0.2	-0.0
Reaction Time	0.2	0.4	1.3	-0.4	-0.2	1.1	-0.4	-0.2	-0.7	-0.3	-0.2	-1.0	-1.1	-1.0	-0.2	0.3	-0.9	-0.7	-0.5
Ovarian Cancer	0.2	0.2	0.9	0.6	-0.2	-0.6	-0.1	0.0	-0.2	-0.9	-0.8	-0.4	-0.2	0.3	-0.9	0.4	-0.0	0.7	0.0
Crohns Disease (2012)	0.2	0.3	1.1	-0.2	-0.2	0.2	-0.9	-0.7	-0.2	0.9	-0.2	-1.0	-0.0	-0.8	-0.4	0.6	-0.6	-0.9	-0.7
Neuroticism (2016)	0.2	0.4	1.0	0.5	-0.3	-0.3	-0.7	-0.7	-0.5	-0.9	-0.9	0.8	0.0	1.0	-0.5	0.7	0.0	0.8	0.3
Blood White Count	0.2	1.6	9.1	0.8	-1.8	-1.0	-0.2	-0.3	-3.0	-0.3	-1.3	-0.8	2.9	-0.4	-0.2	1.1	-0.9	-1.2	-0.9
Smoking Status	0.2	0.5	2.1	1.0	-0.8	-0.5	-0.4	-0.1	1.5	0.2	0.0	0.4	0.3	1.2	-0.9	-0.1	0.6	0.6	0.9
Neuroticism	0.2	0.4	1.6	0.2	0.2	0.1	-0.1	1.0	0.6	0.6	1.3	0.9	-0.2	-0.7	-0.3	0.4	0.8	0.6	1.3
Number of treatments/medications taken	0.2	0.3	1.0	0.1	0.6	-0.3	0.8	0.4	-1.0	-0.6	0.4	0.9	1.0	0.2	0.2	0.5	0.7	0.6	0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.2	0.1	-0.4	-0.1	0.0	0.6	0.2	0.1	0.1	0.6	0.7	-1.1	-0.3	1.1	0.0	-0.1	0.0
Taking other prescription medications	0.2	0.2	1.7	0.1	0.4	-0.1	0.3	0.3	-0.8	-0.6	-0.4	0.6	1.3	-0.7	0.1	0.0	0.3	0.1	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	2.8	-0.4	0.4	-0.1	-0.8	-0.3	0.1	-1.7	-0.2	-0.3	-0.4	-0.5	-0.5	-0.8	-0.5	-0.9	-0.3
Financial difficulties in last 2 years	0.2	0.3	2.6	-0.8	1.6	0.5	-0.1	-0.8	0.0	-0.4	-0.0	0.2	-0.4	0.2	0.8	-0.3	-0.2	-0.0	-0.1
Neuroticism score	0.2	0.4	1.8	0.1	0.6	0.1	-0.1	0.3	0.4	0.3	1.3	1.2	0.7	-0.5	0.4	0.2	0.9	0.5	1.0
Worrier / anxious feelings	0.2	0.3	1.4	0.1	-0.2	-0.7	-0.5	-1.2	-0.3	0.0	0.7	0.4	0.9	-0.9	0.1	-0.5	0.3	-0.5	0.4
Depression (self-reported)	0.2	0.2	0.8	0.9	0.5	-0.8	0.9	-0.3	-0.0	0.4	-0.4	-0.0	0.7	0.3	0.8	0.3	-0.1	0.1	-0.3
Exposure to tobacco smoke at home	0.2	0.2	1.2	-0.1	0.8	-0.4	0.0	0.2	1.1	-0.1	0.6	0.4	0.1	1.0	0.2	-0.4	0.5	0.3	0.2
Pulse wave reflection index	0.2	0.2	1.1	0.6	0.6	-0.0	0.1	-0.4	0.1	0.4	-0.1	0.3	0.2	0.9	0.4	0.4	0.6	1.0	0.5
Loud music exposure frequency	0.2	0.3	0.9	-0.7	0.9	0.4	-0.8	-0.2	0.5	0.1	0.4	-0.9	-0.0	-0.5	-0.2	-0.7	-0.3	-0.3	-0.6
Medication: Paracetamol	0.2	0.3	1.2	-0.4	0.1	-1.1	0.4	0.1	1.1	0.8	0.7	-0.0	1.0	-0.2	-0.1	-0.5	0.0	-0.6	-0.3
Medication for pain relief, constipation, heartburn	0.2	0.3	2.2	-0.3	0.1	0.7	-0.6	0.1	-1.0	-1.5	-0.4	-0.3	-0.6	0.5	0.0	0.4	-0.2	0.3	-0.0
Overall health rating	0.2	0.4	2.7	0.2	0.5	0.6	-0.5	-1.0	-1.6	-0.4	-0.3	0.4	1.6	0.1	0.5	-0.5	0.2	0.1	0.0
Chest pain or discomfort	0.2	0.3	1.0	1.0	1.0	0.8	1.0	0.1	0.1	-0.6	-0.7	-0.3	0.9	0.2	-0.6	0.5	0.2	0.2	-0.3
Medication: Aspirin	0.2	0.2	1.1	-0.0	-0.6	-0.2	-0.7	-0.2	0.6	-0.5	-0.6	0.6	-0.3	-0.4	-0.5	0.4	-0.5	-1.0	-0.3
Supplements: Vitamin C	0.2	0.2	1.5	0.0	-1.2	0.3	-0.3	0.4	0.3	-0.2	-0.3	-0.2	-0.4	-0.4	0.1	-0.2	-0.2	-0.9	-0.1
Smoking status: Previous	0.2	0.3	1.4	0.2	-0.0	1.0	-0.7	0.6	0.8	0.7	1.2	-0.2	0.6	-0.3	0.6	-0.2	0.5	0.1	0.5
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.0	0.0	0.1	-0.2	0.3	1.0	1.0	0.7	-0.5	-0.7	-0.7	0.2	0.3	-0.7	-0.4	-0.4	-0.1
Loneliness, isolation	0.2	0.3	1.7	0.1	1.1	0.6	-0.4	0.6	0.7	-0.5	0.5	0.0	1.3	-0.3	0.2	-0.6	0.5	0.1	0.0
Diabetes diagnosed by doctor	0.2	0.4	1.7	0.7	-0.2	0.1	0.5	0.4	-0.3	-0.2	0.9	0.9	0.4	0.4	-0.3	-0.1	1.0	0.8	1.3
Miserableness	0.2	0.3	1.3	-1.1	-0.6	-0.5	-0.7	0.2	0.5	0.4	1.1	0.0	-0.1	-1.1	-0.2	-0.5	-0.0	-0.6	0.0
Ever taken oral contraceptive pill	0.2	0.2	1.0	0.5	0.7	-0.4	1.0	-0.2	0.3	-0.2	0.7	0.5	0.6	0.4	0.4	0.2	0.4	0.5	0.2
Mother’s age at death	0.2	0.2	1.5	-0.9	0.1	-0.3	-0.1	1.2	-0.6	-0.2	0.2	0.2	0.3	0.4	0.9	0.6	-0.2	-0.2	0.1
High cholesterol (Self-reported)	0.2	0.3	0.9	-0.6	-0.7	-1.0	-0.1	-0.3	-0.4	-0.5	-0.1	-0.3	-0.0	0.4	-0.8	-0.9	-0.4	-0.7	-0.5
Medication: Bendroflumethiazide	0.2	0.3	3.1	0.7	-0.1	-0.2	-0.1	-0.5	-1.0	-1.8	-1.0	0.3	0.3	0.3	0.1	0.1	0.0	0.1	0.2
Worry (Nagel 2018)	0.1	0.2	0.8	-0.3	0.2	0.1	-0.4	-0.4	-0.3	-0.1	0.8	0.1	-0.6	-0.9	-0.7	-0.2	-0.1	-0.4	0.0
Prostate Cancer	0.1	0.2	1.3	0.5	-0.2	-0.3	0.2	-0.5	1.1	0.3	-0.1	0.3	-0.5	-0.2	-0.6	0.2	0.4	0.2	0.6
Lupus	0.1	0.2	0.9	-0.4	-0.1	-0.2	-0.4	-0.1	0.2	-0.8	-0.3	0.1	0.2	-0.8	0.4	0.2	-0.2	-0.2	1.0
Tanning	0.1	0.6	4.7	0.6	0.0	0.9	-1.2	0.2	2.2	1.5	0.4	-0.7	-0.3	0.5	-0.1	-0.3	0.0	-0.6	-0.3
Average weekly spirits intake	0.1	0.2	1.0	-0.7	0.1	-0.4	0.5	0.2	-0.6	0.3	-0.0	-0.3	-0.1	-0.5	0.2	-1.0	-0.5	-0.2	-0.3
Stomach or abdominal pain in last month	0.1	0.1	1.0	-0.1	0.2	0.3	-0.0	0.3	-0.4	-1.0	-0.3	-0.1	-0.6	0.3	-0.3	0.5	0.1	0.3	0.1
Past tobacco smoking	0.1	0.2	0.8	0.2	-0.4	-0.4	0.9	0.2	-0.5	-0.4	-0.9	0.6	-0.6	0.2	-0.5	0.8	-0.3	0.1	-0.2
Diabetes (self-reported)	0.1	0.2	0.7	0.7	-0.7	0.2	-0.3	0.2	-0.7	-0.1	0.4	0.4	0.2	0.2	-0.6	-0.6	0.4	0.1	0.9
Had major operations	0.1	0.1	0.7	-0.3	-0.1	-0.1	-0.5	0.1	-0.1	-0.1	0.2	0.6	-0.6	-0.6	-0.1	-0.9	0.1	-0.2	0.5
Medication for cholesterol	0.1	0.2	1.0	-0.6	-0.4	-1.0	0.1	-0.2	1.0	0.4	-0.1	-0.1	-0.5	-0.0	-0.7	0.2	0.1	-0.1	-0.0
Medication: Aspirin	0.1	0.2	1.0	0.0	0.1	0.2	-0.3	0.0	1.0	-0.4	-0.1	0.7	0.0	0.1	-0.1	0.7	-0.2	-0.7	-0.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.8	0.4	0.1	0.1	0.2	-0.0	-0.2	-0.3	-0.2	0.4	-0.4	0.9	-0.7	0.2	0.4	0.1	0.2
Hair Pigment	0.0	0.5	2.2	-0.2	0.6	1.5	-0.8	0.5	0.5	0.8	0.9	-0.2	-1.2	-0.7	1.1	0.0	0.2	0.1	1.2

Hub : Genes

UBE2Q2P1

Models

Trait associations