Best TWAS P=1.06e-36 · Best GWAS P=1.42e-151 conditioned to 1.2e-75
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FTO | 0.11 | 0.00 | bslmm | 739 | 0.02 | 1.6e-03 | -0.95 | 12 | 2.8e-35 | 0.38 | 0.09 | 0.55 | TRUE |
| 2 | GTEx | Testis | AKTIP | 0.19 | 0.00 | enet | 26 | 0.00 | 1.9e-01 | 0.25 | 13 | 1.1e-36 | 0.51 | 0.03 | 0.40 | TRUE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | FTO | 0.27 | 0.16 | enet | 13 | 0.14 | 6.7e-05 | -2.22 | 10 | 2.9e-25 | 0.33 | 0.11 | 0.32 | TRUE |