[Hub]/) : Traits : Leg fat mass (right) : ← →

chr1:173,178,453-175,663,031

Best TWAS P=1.89e-10 · Best GWAS P=2.94e-09 conditioned to 0.796

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	RC3H1	0.12	0.06	lasso	2	0.06	3.2e-03	5.7	-5.6	1.8e-08	-0.98	0.04	0.79	FALSE
2	GTEx	Artery Tibial	RC3H1	0.09	0.07	lasso	2	0.07	2.6e-06	5.7	-5.7	1.1e-08	-0.98	0.02	0.97	FALSE
3	GTEx	Breast Mammary Tissue (Male)	RC3H1	0.07	0.11	enet	3	0.07	9.9e-03	5.9	-5.8	4.8e-09	-1.00	0.02	0.62	FALSE
4	GTEx	Breast Mammary Tissue (Female)	RABGAP1L	0.19	0.00	lasso	3	0.01	2.0e-01	5.7	6.4	1.9e-10	0.92	0.06	0.43	TRUE
5	GTEx	Esophagus Muscularis	RC3H1	0.10	0.08	lasso	13	0.06	1.2e-04	5.7	-5.3	1.1e-07	-0.98	0.02	0.97	FALSE
6	GTEx	Nerve Tibial	RC3H1	0.09	0.06	enet	7	0.07	7.0e-06	5.2	-5.5	4.0e-08	-0.97	0.05	0.95	FALSE
7	GTEx	Ovary	RC3H1	0.32	0.03	lasso	8	0.07	8.6e-03	5.7	-6.0	2.3e-09	-0.82	0.02	0.58	FALSE
8	METSIM	Adipose	SERPINC1	0.10	0.09	bslmm	271	0.09	1.2e-13	5.4	5.9	3.0e-09	0.95	0.05	0.95	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	RABGAP1L	0.07	0.01	lasso	3	0.01	1.2e-02	5.3	5.2	1.6e-07	0.97	0.03	0.94	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	SERPINC1	0.14	0.09	blup	47	0.09	1.2e-17	5.4	5.2	2.0e-07	0.93	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SERPINC1	0.11	0.06	blup	47	0.05	3.7e-06	5.4	5.3	1.1e-07	0.88	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CACYBP	0.11	0.05	lasso	2	0.04	9.6e-04	5.3	5.3	1.1e-07	0.95	0.00	0.96	FALSE
13	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MRPS14	0.12	0.01	lasso	4	0.01	1.1e-01	5.3	5.4	5.6e-08	0.94	0.00	0.92	FALSE
14	The Cancer Genome Atlas	Stomach Adenocarcinoma	SERPINC1	0.09	0.04	lasso	5	0.04	5.8e-04	5.7	5.2	2.0e-07	0.96	0.00	0.99	FALSE
15	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RC3H1	0.13	-0.01	blup	58	0.01	1.4e-01	5.7	6.0	1.9e-09	0.80	0.01	0.24	FALSE