TWAS hub - SERPINC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.1019	0.0327	4.8e-10	0.087	0.087	0.089	0.092	0.089	5.0e-13	5.2e-13	2.7e-13	1.2e-13	3.6e-13
2	TCGA	Breast Invasive Carcinoma	0.1406	0.0488	0.0e+00	0.090	0.089	0.086	NA	0.087	7.4e-18	1.2e-17	4.4e-17	NA	2.1e-17
3	TCGA	Colon Adenocarcinoma	0.1040	0.0510	9.8e-05	0.064	0.062	0.049	NA	0.051	1.4e-04	1.8e-04	8.2e-04	NA	6.6e-04
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.1066	0.0411	8.2e-11	0.062	0.048	0.044	NA	0.043	1.6e-07	3.6e-06	1.1e-05	NA	1.2e-05
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.1269	0.0662	7.3e-07	0.031	0.031	0.030	NA	0.028	1.9e-04	1.7e-04	2.3e-04	NA	3.3e-04
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.3110	0.1700	4.8e-07	0.074	0.028	0.037	NA	0.051	5.2e-05	9.9e-03	3.4e-03	NA	6.8e-04
7	TCGA	Brain Lower Grade Glioma	0.0583	0.0282	2.6e-05	0.022	0.021	0.019	NA	0.019	1.2e-03	1.7e-03	2.5e-03	NA	2.9e-03
8	TCGA	Lung Adenocarcinoma	0.0783	0.0338	1.6e-07	0.042	0.054	0.048	NA	0.051	1.1e-05	5.8e-07	2.3e-06	NA	1.2e-06
9	TCGA	Lung Squamous Cell Carcinoma	0.1175	0.0789	7.5e-05	0.026	0.017	0.036	NA	0.019	5.4e-04	3.9e-03	6.0e-05	NA	3.0e-03
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.0760	0.0560	5.8e-03	0.019	0.021	0.051	NA	0.042	1.7e-02	1.3e-02	2.1e-04	NA	8.0e-04
11	TCGA	Pheochromocytoma and Paraganglioma	0.3150	0.1390	2.3e-06	0.113	0.116	0.121	NA	0.114	3.2e-05	2.4e-05	1.6e-05	NA	2.9e-05
12	TCGA	Prostate Adenocarcinoma	0.0766	0.0339	9.6e-06	0.011	0.034	0.023	NA	0.026	2.1e-02	1.6e-04	1.6e-03	NA	8.4e-04
13	TCGA	Soft Tissue Sarcoma	0.1230	0.0630	3.9e-05	0.076	0.053	0.057	NA	0.077	2.8e-05	4.4e-04	2.7e-04	NA	2.4e-05
14	TCGA	Stomach Adenocarcinoma	0.0950	0.0460	1.0e-05	0.038	0.040	0.034	NA	0.041	9.1e-04	6.6e-04	1.7e-03	NA	5.8e-04
15	TCGA	Thyroid Carcinoma	0.1400	0.0530	8.2e-10	0.052	0.062	0.052	NA	0.065	8.0e-06	1.2e-06	8.8e-06	NA	6.6e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Schizophrenia vs Biploar Disorder	11.0	14.5	23.1	-4.4	-3.7	-3.0	-4.2	-4.3	-4.4	-4.5	-2.5	-1.1	-4.8	-3.3	-1.5	-4.2	-4.4	-4.3
Prospective memory result	9.1	11.2	18.0	-3.5	-3.7	-2.2	-4.2	-3.8	-3.6	-3.5	-3.0	-2.1	-2.5	-2.5	-3.1	-3.8	-3.9	-3.9
Impedance of arm (left)	7.1	32.8	41.5	-6.4	-6.4	-5.5	-5.2	-5.9	-5.9	-5.6	-6.2	-4.8	-4.8	-6.1	-5.9	-5.9	-5.9	-5.2
Alcohol usually taken with meals	6.6	10.7	19.7	3.1	2.7	3.3	3.4	3.4	3.2	4.4	2.2	0.7	3.4	4.0	0.9	3.4	3.8	4.4
Body mass index (BMI)	6.5	27.8	40.2	6.3	5.9	3.9	5.6	5.3	5.5	4.7	5.6	5.0	4.3	5.0	5.4	5.5	5.7	4.8
Number of incorrect matches in round	6.4	10.6	12.7	-3.4	-3.6	-2.8	-3.4	-3.6	-3.4	-3.4	-3.1	-2.4	-2.9	-3.3	-3.1	-3.5	-3.5	-3.3
Impedance of arm (right)	6.4	29.9	37.7	-6.1	-6.1	-5.5	-4.6	-5.6	-5.6	-5.2	-6.1	-4.4	-4.7	-5.8	-6.1	-5.7	-5.4	-4.7
Alcohol intake versus 10 years previously	6.3	9.4	13.0	-3.0	-3.6	-2.5	-2.6	-3.6	-3.5	-2.9	-2.9	-2.7	-3.2	-2.1	-3.5	-3.4	-3.1	-3.0
Impedance of whole body	6.0	30.4	38.9	-6.0	-6.2	-5.4	-4.8	-5.8	-5.8	-5.3	-6.1	-4.7	-4.4	-5.6	-6.1	-5.7	-5.5	-4.8
BMI	5.8	33.6	48.6	7.0	6.5	4.5	6.0	5.9	6.3	5.1	6.5	5.4	4.3	5.8	6.2	5.9	6.1	4.8
Vitamin and mineral supplements	5.8	7.9	11.6	3.2	2.9	1.8	3.3	2.9	2.9	3.0	2.4	3.0	2.4	2.3	2.1	2.8	3.4	3.3
Leg fat mass (right)	5.8	22.6	35.2	5.9	5.2	3.3	5.3	4.8	5.0	4.4	4.8	4.7	3.7	4.7	4.5	4.8	5.2	4.4
Leg fat percentage (right)	5.6	20.4	33.6	5.8	5.0	2.8	5.2	4.6	4.7	4.0	4.4	4.1	3.8	4.2	4.3	4.7	5.0	4.3
Leg fat mass (left)	5.4	20.9	32.2	5.7	4.9	3.0	5.1	4.6	4.7	4.2	4.6	4.8	3.6	4.5	4.3	4.6	5.0	4.3
Medication: Paracetamol	5.2	8.0	11.3	-2.8	-2.8	-3.3	-2.7	-2.7	-2.6	-3.4	-3.2	-3.2	-1.1	-2.6	-2.5	-2.6	-3.1	-3.0
Schizophrenia (2014)	5.1	11.3	22.1	-3.4	-3.8	-2.4	-3.6	-4.4	-4.0	-3.5	-2.3	-1.2	-4.7	-2.1	-2.6	-4.0	-3.4	-3.4
Respiratory disease	5.1	11.4	17.3	-3.4	-3.2	-3.0	-3.8	-3.4	-3.7	-4.2	-2.8	-2.4	-2.6	-4.2	-2.0	-3.5	-3.6	-3.9
Waist circumference	5.0	18.1	27.1	5.2	4.8	2.8	4.8	4.3	4.6	3.7	4.5	4.3	3.4	3.7	4.4	4.5	4.6	3.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.9	5.8	11.1	2.1	2.6	1.8	1.8	2.6	2.4	2.1	2.5	3.3	2.2	1.4	3.0	2.4	2.5	2.7
Arm fat mass (right)	4.7	19.5	28.7	5.4	4.8	3.4	4.6	4.4	4.5	4.0	4.8	4.4	3.8	4.0	4.5	4.5	4.8	4.0
Arm fat mass (left)	4.7	19.4	28.1	5.3	4.8	3.3	4.6	4.5	4.6	3.9	4.7	4.1	4.0	4.1	4.5	4.6	4.7	4.0
Leg fat percentage (left)	4.6	16.8	27.7	5.3	4.5	2.3	4.8	4.1	4.3	3.6	3.9	4.1	3.4	3.9	3.8	4.2	4.6	4.0
Breastfed as a baby	4.3	5.3	7.3	2.7	2.4	1.9	2.6	2.5	2.7	2.5	2.1	1.1	2.2	2.6	1.7	2.7	2.3	2.1
Weight	4.2	20.5	28.2	5.3	4.8	3.6	4.8	4.6	4.8	4.4	4.7	4.4	3.7	4.7	4.1	4.7	4.8	4.1
Migraine (self-reported)	4.2	5.3	10.6	-2.1	-2.2	-3.3	-1.4	-2.1	-2.0	-2.7	-2.9	-2.3	-1.8	-2.2	-2.2	-2.1	-2.4	-2.3
Whole body fat mass	4.1	17.0	26.3	5.1	4.4	2.8	4.5	4.1	4.3	3.6	4.3	4.3	3.5	3.8	4.0	4.2	4.5	3.7
Lung cancer (father)	4.0	4.6	8.6	-1.7	-2.3	-1.1	-2.6	-2.7	-2.5	-2.3	-0.9	-0.3	-2.9	-2.4	-1.2	-2.7	-2.2	-2.4
Qualifications: O levels/GCSEs or equivalent	4.0	6.3	8.5	2.4	2.6	2.8	2.2	2.5	2.6	2.7	2.9	2.6	1.5	2.6	2.6	2.5	2.6	2.3
Comparative body size at age 10	4.0	11.0	17.1	3.6	3.5	2.7	3.2	3.2	3.1	3.0	3.6	4.1	1.9	3.7	3.7	3.2	3.5	3.2
Medication: Ibuprofen	4.0	4.8	7.0	-2.5	-2.0	-2.4	-1.9	-2.1	-1.9	-2.5	-2.5	-1.9	-1.3	-2.6	-1.9	-2.1	-2.5	-2.4
Family relationship satisfaction	4.0	4.9	7.8	-2.3	-2.5	-1.2	-2.6	-2.7	-2.7	-2.3	-1.3	-0.4	-2.8	-2.2	-1.4	-2.6	-2.4	-2.1
Supplements: Calcium	4.0	4.4	6.2	-2.3	-2.1	-1.6	-2.2	-2.2	-2.5	-2.3	-1.9	-1.7	-1.6	-2.2	-1.7	-2.2	-2.2	-2.2
Arm predicted mass (left)	3.9	19.9	24.4	4.9	4.6	4.4	4.0	4.6	4.7	4.6	4.8	3.9	4.0	4.8	4.3	4.7	4.5	3.9
Multivitamins +/- minerals	3.8	4.9	7.9	-2.4	-2.2	-1.1	-2.8	-2.5	-2.5	-2.3	-1.6	-2.1	-2.1	-1.6	-1.6	-2.5	-2.5	-2.6
Arm fat-free mass (left)	3.8	19.5	23.8	4.9	4.6	4.4	3.9	4.5	4.7	4.5	4.8	3.8	4.0	4.7	4.3	4.7	4.4	3.8
Arm fat percentage (right)	3.7	14.5	21.9	4.7	4.2	2.5	4.3	3.8	4.0	3.3	3.9	3.9	3.3	3.4	3.7	3.9	4.3	3.6
Chronic bronchitis/emphysema (mother)	3.7	4.3	7.8	-2.2	-2.0	-1.1	-2.8	-2.3	-2.1	-2.3	-1.2	-1.4	-2.3	-2.1	-1.0	-2.2	-2.4	-2.6
Hypothyroidism (self reported)	3.6	8.3	10.7	-3.1	-3.1	-3.1	-2.4	-3.1	-3.1	-3.3	-2.9	-2.2	-2.4	-2.3	-2.7	-2.9	-3.2	-3.1
Impedance of leg (left)	3.6	17.4	23.4	-4.4	-4.8	-3.9	-3.8	-4.5	-4.5	-3.9	-4.7	-3.8	-3.3	-3.9	-4.8	-4.4	-4.1	-3.4
Hip circumference	3.5	15.2	23.1	4.8	4.2	3.2	4.2	4.0	4.1	4.0	3.9	2.9	3.4	4.1	3.3	4.1	4.3	3.5
Medication: Paracetamol	3.5	5.8	9.3	-2.3	-2.2	-2.7	-2.5	-2.2	-2.3	-3.0	-2.6	-2.9	-0.9	-2.3	-1.7	-2.3	-2.7	-2.8
Headache pain in last month	3.5	5.9	12.5	-2.6	-2.3	-1.6	-3.5	-2.4	-2.7	-3.3	-1.5	-2.9	-0.8	-2.7	-0.2	-2.2	-2.7	-2.7
Arm predicted mass (right)	3.5	17.8	22.3	4.6	4.4	4.2	3.7	4.3	4.4	4.2	4.7	3.8	3.6	4.5	4.3	4.5	4.1	3.6
Arm fat percentage (left)	3.4	13.7	20.7	4.5	4.1	2.4	4.1	3.7	3.8	3.1	3.9	3.7	3.2	3.2	3.8	3.8	4.1	3.4
Allergy	3.3	7.5	13.9	3.2	2.8	1.3	3.7	2.7	3.1	2.7	2.3	2.4	2.5	2.9	1.9	3.0	3.0	2.7
Arm fat-free mass (right)	3.3	17.0	20.8	4.5	4.3	4.0	3.7	4.2	4.4	4.2	4.6	3.8	3.5	4.4	4.2	4.4	4.0	3.5
Wheeze or whistling in the chest in last year	3.1	5.5	10.7	-2.2	-2.1	-1.7	-3.0	-2.5	-2.3	-3.0	-1.2	-0.8	-2.8	-2.4	-0.5	-2.6	-3.0	-3.3
Asthma (self-reported)	3.0	5.9	10.4	-2.6	-2.4	-2.0	-3.0	-2.4	-2.7	-3.0	-1.9	-1.6	-1.5	-3.2	-1.2	-2.6	-2.6	-2.7
Medication: Gliclazide	3.0	3.4	4.5	2.1	2.1	1.9	1.6	2.0	2.1	1.9	1.9	1.4	1.2	1.6	1.9	1.9	1.9	1.8
Schizophrenia (2018)	2.9	5.9	15.8	-2.2	-2.7	-1.2	-2.8	-3.3	-3.0	-2.5	-1.1	-0.2	-4.0	-1.1	-1.4	-3.1	-2.4	-2.5
HbA1C	2.9	3.2	11.8	1.9	1.8	1.1	1.7	1.5	2.0	1.5	1.6	3.4	1.6	1.2	1.2	1.6	1.8	1.7
Body fat percentage	2.9	11.5	19.6	4.4	3.7	1.8	4.0	3.3	3.5	2.8	3.5	3.5	2.9	3.0	3.3	3.5	3.8	3.1
Basal metabolic rate	2.9	16.3	19.4	4.4	4.2	3.8	3.8	4.2	4.3	4.1	4.4	3.9	3.3	4.2	3.9	4.2	4.1	3.5
Relative age voice broke	2.8	4.3	8.2	2.3	1.8	1.3	2.9	2.0	2.0	2.1	2.1	1.8	1.7	2.4	1.5	2.4	2.3	2.1
Age when periods started (menarche)	2.8	6.7	11.5	2.3	2.4	1.7	3.1	3.0	2.8	3.2	1.2	1.1	3.3	2.7	0.8	2.9	3.0	3.4
Trunk fat mass	2.8	11.9	19.3	4.4	3.6	2.0	4.0	3.4	3.6	2.9	3.6	3.6	2.9	3.2	3.3	3.6	3.8	3.1
Heel bone mineral density (BMD) T-score, automated (right)	2.8	6.4	11.8	2.8	2.9	1.6	2.4	2.4	2.0	1.6	3.1	3.4	2.0	2.3	3.4	2.5	2.6	1.9
Chronotype (morning person)	2.7	6.2	9.8	-3.1	-3.1	-1.5	-2.6	-2.8	-3.0	-1.8	-2.7	-2.0	-2.0	-2.0	-3.1	-2.8	-2.3	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	2.7	6.1	10.4	2.8	2.7	1.7	2.5	2.3	2.3	1.8	2.9	3.2	1.5	2.5	3.1	2.5	2.4	2.0
Asthma	2.7	5.2	9.3	-2.4	-2.2	-1.8	-3.0	-2.3	-2.5	-2.9	-1.7	-1.6	-1.1	-3.0	-1.0	-2.4	-2.4	-2.6
Depression (self-reported)	2.7	3.3	8.6	1.7	2.0	1.2	1.2	1.9	1.6	1.0	2.0	2.7	1.7	1.0	2.9	1.7	1.8	1.5
Exposure to tobacco smoke at home	2.7	3.0	5.0	2.0	2.0	1.0	1.6	1.9	2.0	1.3	1.6	0.8	2.2	1.9	1.9	2.0	1.7	1.3
Medication: Atenolol	2.6	3.3	6.3	2.0	2.2	0.5	2.5	2.3	2.5	1.8	1.0	1.1	1.7	1.1	1.2	2.2	1.8	1.8
Financial situation satisfaction	2.6	3.2	4.6	-2.1	-1.9	-1.8	-1.8	-2.0	-2.1	-2.1	-1.4	-0.2	-2.1	-2.1	-1.1	-2.0	-1.8	-1.5
Number of operations (self-reported)	2.6	3.9	6.1	2.0	2.5	1.9	1.6	2.2	2.2	1.7	1.9	1.5	1.9	2.4	2.2	2.1	1.7	1.2
Tense / ‘highly strung’	2.5	4.2	8.1	-2.5	-1.8	-2.7	-1.9	-1.7	-1.8	-2.5	-2.4	-1.4	-0.8	-2.8	-1.2	-1.7	-2.2	-2.0
Had major operations	2.5	2.9	5.6	2.2	1.8	1.7	1.9	1.7	1.7	2.0	1.5	1.1	1.0	2.4	0.9	1.6	1.9	1.7
Whole body fat-free mass	2.5	14.1	17.1	4.0	3.9	3.7	3.4	3.9	4.1	3.9	4.1	3.6	3.0	4.0	3.7	4.0	3.7	3.2
Mineral and other dietary supplements	2.5	3.3	4.5	2.1	2.0	1.7	2.1	2.0	2.1	2.1	1.9	1.0	1.1	0.7	1.6	2.0	2.0	2.0
Whole body water mass	2.5	14.5	18.0	4.0	3.9	3.9	3.4	3.9	4.1	3.9	4.2	3.7	3.0	4.1	3.8	4.0	3.7	3.2
Ovarian Cancer	2.4	3.2	4.6	2.1	2.0	1.9	1.4	1.9	1.9	1.7	1.9	1.0	2.1	0.8	2.1	1.9	1.9	1.7
Tinnitus: Yes, now most or all of the time	2.4	2.9	5.5	-1.6	-2.0	-1.4	-2.0	-2.3	-2.3	-2.0	-1.0	-0.4	-1.2	-1.1	-1.4	-2.1	-1.3	-1.7
Supplements: Fish oil (including cod liver oil)	2.4	3.2	4.4	-1.8	-1.9	-1.8	-1.8	-1.9	-2.0	-1.9	-2.1	-1.2	-1.3	-0.4	-2.0	-2.1	-1.8	-1.9
Leg fat-free mass (left)	2.3	12.3	15.1	3.8	3.7	3.1	3.4	3.6	3.8	3.5	3.9	3.6	2.6	3.5	3.5	3.7	3.6	3.0
Trunk fat-free mass	2.3	13.3	16.3	3.8	3.7	4.0	3.1	3.8	4.0	3.9	4.0	3.1	3.0	4.0	3.5	3.9	3.5	3.1
Trunk predicted mass	2.3	12.9	15.8	3.7	3.7	4.0	3.0	3.7	3.9	3.9	3.9	3.0	3.0	4.0	3.5	3.8	3.4	3.0
Supplements: Vitamin C	2.3	2.7	4.7	-1.6	-1.8	-1.3	-1.9	-1.6	-1.7	-1.9	-1.5	-2.2	-0.9	-1.8	-1.3	-1.6	-1.8	-1.7
Rheumatoid Arthritis	2.2	3.0	5.2	-1.7	-1.9	-2.3	-1.2	-1.9	-1.8	-1.9	-2.0	-0.7	-1.3	-1.5	-2.0	-1.9	-1.6	-1.6
Impedance of leg (right)	2.2	10.8	14.8	-3.3	-3.7	-3.0	-3.0	-3.4	-3.5	-3.0	-3.8	-3.6	-2.5	-3.1	-3.9	-3.4	-3.3	-2.7
Leg predicted mass (left)	2.2	11.4	14.3	3.6	3.6	3.0	3.3	3.5	3.6	3.3	3.8	3.6	2.5	3.5	3.4	3.5	3.4	2.9
Emphysema/chronic bronchitis	2.2	2.4	5.1	-1.6	-1.0	-1.2	-1.9	-1.5	-1.3	-2.2	-0.8	-1.0	-1.6	-1.8	0.1	-1.5	-2.0	-2.2
Handedness (chirality/laterality): Left-handed	2.2	2.6	4.5	-1.5	-2.1	-0.8	-1.8	-2.0	-2.1	-1.4	-1.2	-1.6	-1.4	-0.5	-1.9	-1.8	-1.5	-1.6
Friendships satisfaction	2.2	2.7	7.1	-1.8	-1.8	-0.6	-1.9	-2.0	-2.0	-1.4	-1.1	-0.7	-2.7	-1.2	-1.2	-2.0	-1.7	-1.3
Supplements: Zinc	2.1	2.3	4.0	-1.4	-1.7	-1.7	-0.7	-1.6	-1.6	-1.4	-1.4	-1.1	-2.0	-1.6	-1.8	-1.6	-1.3	-1.2
Medication for pain relief, constipation, heartburn	2.1	3.6	6.8	1.9	1.7	2.6	1.7	1.6	1.5	2.4	2.4	2.3	0.3	1.6	1.5	1.6	2.1	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.1	2.4	4.7	1.9	1.8	0.6	2.2	1.5	1.6	1.4	1.3	1.4	1.0	1.7	1.2	1.5	1.9	1.7
Bilateral oophorectomy (both ovaries removed)	2.0	2.4	3.8	1.1	1.7	1.3	1.2	1.7	1.5	1.4	1.6	1.7	1.9	0.8	1.9	1.8	1.4	1.5
Qualifications: A levels/AS levels or equivalent	2.0	4.4	6.4	1.9	2.2	1.8	2.3	2.5	2.3	2.4	1.6	1.1	2.0	1.9	1.7	2.4	2.4	2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.2	8.1	1.8	1.5	1.8	2.1	2.0	2.0	2.8	1.6	2.1	1.9	2.2	0.5	2.1	2.4	2.8
Hearing difficulty/problems: Yes	1.9	2.9	4.8	-1.4	-1.7	-1.3	-1.9	-2.1	-2.0	-2.2	-1.0	-1.2	-1.5	-1.7	-0.9	-2.1	-1.6	-2.1
Medication: Co-codamol	1.9	2.2	5.2	1.2	1.9	0.3	1.7	2.0	2.0	1.0	0.8	0.8	2.3	0.7	1.6	2.1	1.1	1.2
Townsend deprivation index at recruitment	1.9	2.6	6.5	-1.4	-1.6	-1.4	-1.5	-2.0	-1.9	-1.7	-1.1	0.2	-2.5	-1.1	-1.2	-2.1	-1.5	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	6.4	-1.8	-1.3	-1.9	-1.7	-1.9	-1.6	-2.5	-0.8	0.1	-2.0	-2.2	-0.1	-1.8	-2.0	-2.4
Number of full brothers	1.9	2.4	3.2	1.5	1.4	1.8	0.9	1.3	1.3	1.6	1.8	1.8	1.3	1.6	1.7	1.4	1.6	1.8
Average weekly fortified wine intake	1.8	2.1	3.2	1.6	1.7	0.9	1.5	1.6	1.7	1.5	1.1	1.4	1.3	0.7	1.2	1.4	1.6	1.8
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	3.3	-1.6	-1.3	-1.6	-1.5	-1.5	-1.3	-1.8	-1.6	-1.2	-0.6	-1.6	-1.2	-1.5	-1.7	-1.8
Medication: Lansoprazole	1.7	1.9	4.8	1.6	1.4	1.1	1.4	1.5	1.5	1.4	1.1	0.2	2.2	0.9	0.9	1.7	1.5	1.3
Commuting to job workplace: Car/motor vehicle	1.7	1.9	3.7	-1.6	-1.4	-1.5	-1.6	-1.6	-1.4	-1.9	-0.9	0.1	-0.8	-1.3	-0.5	-1.4	-1.7	-1.8
Qualifications: nursing, teaching	1.7	2.7	3.9	1.7	2.0	1.7	1.5	1.9	1.6	1.5	1.7	1.3	0.9	1.7	2.0	1.6	1.7	1.5
Mean Putamen Volume	1.6	1.8	3.6	1.0	1.5	0.2	1.9	1.4	1.2	0.9	1.0	1.8	1.0	1.3	1.5	1.4	1.4	1.5
Lung FVC	1.6	7.9	14.9	2.3	2.4	3.9	1.6	2.6	2.7	3.6	3.2	2.7	2.3	2.5	2.3	2.6	3.0	3.6
Eye problems/disorders: Diabetes related eye disease	1.6	1.7	3.3	1.5	1.5	1.6	0.6	1.3	1.1	1.0	1.5	1.5	1.1	1.1	1.8	1.1	1.2	1.2
Trunk fat percentage	1.6	6.4	11.7	3.4	2.6	1.0	3.2	2.4	2.5	1.9	2.6	2.8	2.2	2.0	2.4	2.6	2.9	2.3
Happiness	1.6	1.9	3.8	-1.5	-1.4	-1.4	-0.9	-1.6	-1.6	-1.6	-1.1	-0.7	-1.9	-1.4	-1.0	-1.5	-1.4	-1.2
Average weekly red wine intake	1.6	2.3	3.5	1.2	1.4	1.9	0.8	1.6	1.7	1.7	1.8	1.0	1.4	1.8	1.7	1.7	1.4	1.5
Bipolar Disorder or Schizophrenia	1.5	3.6	10.0	-1.4	-2.3	-1.1	-1.7	-2.6	-2.5	-1.6	-1.2	-0.8	-3.2	-0.1	-2.0	-2.5	-1.4	-1.4
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	4.2	1.3	1.4	1.4	1.2	1.4	1.2	1.0	1.9	0.7	1.1	1.8	2.0	1.7	1.0	0.7
Leg fat-free mass (right)	1.5	8.0	11.0	2.9	2.9	2.4	2.8	2.9	3.1	2.8	3.1	3.3	2.0	3.0	2.7	2.9	2.9	2.4
Cholesterol lowering medication	1.5	2.2	3.9	1.6	1.8	1.9	0.7	1.6	1.5	1.4	1.7	0.6	1.5	0.7	2.0	1.5	1.3	1.3
Intelligence (Savage-Jansen 2018)	1.4	4.3	8.8	2.4	1.6	2.2	2.2	1.6	1.9	2.5	2.3	2.0	-0.5	3.0	1.2	1.6	2.3	2.3
Fasting Glucose	1.4	1.7	5.4	-1.7	-1.5	-2.3	0.3	-0.8	-0.5	-0.9	-2.2	-0.6	-0.4	-0.7	-2.1	-0.4	-1.3	-0.8
Number of treatments/medications taken	1.4	2.5	6.1	-1.3	-1.2	-1.7	-1.7	-1.3	-1.1	-2.2	-1.3	-1.7	-0.3	-2.5	-0.4	-1.1	-2.0	-2.0
Relative age of first facial hair	1.4	2.8	6.2	1.4	1.2	1.4	2.5	1.6	1.7	2.3	1.2	1.0	0.5	2.4	0.4	1.9	1.8	2.2
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	6.2	-1.7	-1.2	-1.1	-1.7	-1.1	-1.2	-1.6	-1.0	-0.6	-0.5	-2.5	-0.4	-1.1	-1.6	-1.5
Leg predicted mass (right)	1.4	7.7	10.8	2.9	2.8	2.4	2.7	2.8	3.0	2.8	3.0	3.3	1.9	3.0	2.6	2.9	2.8	2.3
Reaction Time	1.3	2.4	8.1	-1.0	-1.8	-2.8	0.6	-1.6	-1.4	-1.2	-2.0	-0.8	-1.6	-0.2	-2.9	-1.3	-0.8	-0.7
Age at First Birth	1.3	1.9	3.5	1.6	1.3	0.9	1.8	1.3	1.2	1.5	1.1	1.4	0.7	1.9	0.8	1.2	1.6	1.6
Coronary Artery Disease (CAD)	1.3	1.5	3.5	1.3	1.5	1.3	1.0	1.3	1.9	1.1	1.4	0.6	1.1	0.5	1.5	1.3	1.1	0.8
Average weekly spirits intake	1.3	1.6	3.1	1.4	1.3	0.2	1.8	1.5	1.7	1.1	0.8	1.0	1.5	0.1	0.8	1.6	1.4	1.4
Number of live births	1.3	1.8	4.9	1.3	1.2	1.9	0.8	1.1	1.2	1.4	1.7	0.9	0.6	2.2	1.5	1.2	1.1	1.1
Mood swings	1.3	2.3	4.6	1.5	1.8	-0.1	2.1	1.8	1.9	1.1	0.8	1.5	1.9	0.8	1.2	1.7	1.6	1.5
Heart disease (siblings)	1.3	1.6	3.8	1.2	1.5	1.1	0.9	1.8	1.6	1.2	0.7	-0.8	2.0	0.7	1.2	1.7	0.8	0.8
Pack years of smoking	1.3	2.0	3.2	-1.6	-1.5	-1.6	-1.2	-1.6	-1.4	-1.8	-0.8	-0.1	-1.6	-1.6	-0.5	-1.4	-1.6	-1.6
Worry (Nagel 2018)	1.2	2.6	5.6	-1.9	-1.3	-2.2	-1.5	-1.4	-1.3	-2.3	-1.6	-0.2	-0.7	-2.4	-0.6	-1.4	-1.8	-1.8
Blood Red Count	1.2	11.4	34.7	-2.9	-2.9	-5.9	-1.3	-3.1	-3.1	-4.1	-4.5	-1.5	-2.1	-4.1	-3.3	-3.1	-2.9	-3.0
Allergy or Eczema	1.2	3.2	6.1	-2.2	-1.8	-0.8	-2.5	-1.6	-2.0	-1.5	-1.9	-2.2	-1.3	-1.9	-1.5	-1.9	-1.8	-1.3
Pack years adult smoking proportion	1.2	1.9	2.9	-1.6	-1.5	-1.7	-1.1	-1.6	-1.3	-1.7	-0.8	0.2	-1.6	-1.6	-0.6	-1.4	-1.5	-1.5
High blood pressure (mother)	1.2	1.7	2.7	-1.2	-1.0	-1.6	-0.9	-1.1	-1.3	-1.4	-1.5	-0.1	-1.6	-1.6	-1.1	-1.5	-1.4	-1.6
Ever highly irritable/argumentative for 2 days	1.2	1.5	2.2	0.9	1.2	1.1	1.3	1.2	1.4	1.3	1.1	1.5	0.6	1.4	1.0	1.2	1.2	1.4
Neck or shoulder pain in last month	1.2	1.7	4.1	1.2	1.6	-0.4	2.0	1.7	1.7	1.1	-0.1	0.6	2.0	0.5	0.1	1.4	1.4	1.1
Alcohol intake frequency.	1.2	2.7	6.5	-1.3	-1.7	-0.6	-1.7	-1.6	-2.0	-1.4	-1.5	-2.5	-1.3	-1.5	-1.6	-1.6	-1.8	-1.8
Overall health rating	1.2	2.5	5.2	-1.5	-1.2	-1.7	-1.7	-1.6	-1.5	-2.2	-1.1	-0.8	-1.0	-2.2	-0.4	-1.5	-1.9	-2.3
Ever had bowel cancer screening	1.2	1.5	3.8	1.2	1.3	1.8	0.2	1.2	1.1	0.8	1.8	-0.4	1.5	0.5	1.9	1.3	0.7	0.6
Alcohol drinker status: Never	1.2	1.4	3.3	1.2	1.5	0.5	1.8	1.4	1.6	1.4	0.6	1.1	0.8	1.0	0.4	1.3	1.3	1.2
Fractured/broken bones in last 5 years	1.2	1.5	4.2	-1.4	-1.4	-1.2	-0.7	-1.1	-0.9	-0.7	-1.7	-1.5	-1.0	-0.7	-2.0	-1.0	-1.3	-1.0
Age started oral contraceptive pill	1.2	1.5	3.3	1.3	0.9	0.4	1.8	1.2	1.2	1.5	0.4	0.6	1.6	1.1	-0.1	1.4	1.4	1.6
Lupus	1.1	1.7	5.8	1.4	1.5	0.3	1.1	1.8	2.0	0.9	0.4	0.4	2.4	-0.3	1.3	1.6	0.9	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	7.7	0.7	1.3	1.5	-0.2	1.0	0.9	0.3	2.1	2.0	0.8	0.5	2.8	1.0	0.7	0.7
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.4	-1.6	-1.2	-1.0	-1.6	-0.9	-1.1	-1.5	-0.9	-0.7	-0.2	-1.8	-0.2	-0.8	-1.4	-1.4
Illnesses of father: Heart disease	1.1	1.5	4.3	1.4	1.3	0.8	1.1	1.2	1.1	1.2	1.0	2.1	0.3	1.6	0.9	0.9	1.3	1.3
Blood Eosinophil Count	1.0	8.0	14.0	-3.1	-2.6	-3.5	-2.3	-2.4	-2.8	-3.2	-3.5	-1.6	-1.4	-3.7	-2.8	-2.7	-2.8	-2.9
Blood White Count	1.0	7.6	13.2	-2.9	-2.6	-2.4	-2.7	-2.9	-3.2	-3.6	-1.8	-2.4	-2.4	-3.4	-0.9	-2.6	-3.1	-3.3
Peak expiratory flow (PEF)	1.0	2.3	4.1	1.3	1.4	1.2	1.9	1.5	1.6	1.9	1.2	1.6	0.7	2.0	0.6	1.5	1.8	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	2.0	1.0	1.0	1.1	0.7	1.1	0.9	0.9	1.3	1.2	1.4	1.1	1.4	1.2	1.2	1.3
Shortness of breath walking on level ground	1.0	1.2	1.9	-1.1	-1.1	-1.3	-0.6	-1.3	-1.3	-1.1	-1.3	-0.3	-1.3	-0.3	-1.2	-1.4	-0.9	-0.9
Long-standing illness, disability or infirmity	1.0	1.5	3.1	-1.3	-0.9	-0.6	-1.8	-1.3	-1.4	-1.6	-0.5	0.2	-1.4	-1.2	0.1	-1.4	-1.5	-1.5
Basal cell carcinoma (self-reported)	1.0	1.2	3.3	1.1	1.5	-0.2	1.8	1.4	1.6	0.9	0.4	1.3	0.3	0.5	0.7	1.0	1.1	0.7
Sensitivity / hurt feelings	0.9	1.5	3.2	1.0	1.2	-0.1	1.8	1.4	1.7	1.1	0.5	1.8	0.8	1.2	0.7	1.3	1.1	1.5
Serious illness, injury or assault to yourself	0.9	1.0	4.7	-0.8	-1.1	-1.8	0.3	-0.6	-0.4	-0.4	-1.8	-0.6	0.1	-0.9	-2.2	-0.4	-0.6	-0.4
Hayfever, allergic rhinitis or eczema	0.9	2.0	4.4	-1.8	-1.4	-0.2	-2.1	-1.3	-1.6	-1.0	-1.4	-1.6	-1.4	-1.1	-1.2	-1.6	-1.3	-0.8
Qualifications: None of the above	0.9	1.9	5.3	-1.2	-1.4	-2.3	-0.8	-1.4	-1.3	-2.0	-1.4	-0.6	-0.6	-1.4	-0.9	-1.2	-1.5	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	6.2	1.2	1.2	2.5	1.0	1.5	1.4	2.4	1.8	1.3	1.7	2.1	0.9	1.6	1.9	2.2
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.3	1.1	1.4	0.5	0.8	1.1	1.0	0.6	1.0	1.8	1.0	0.9	1.4	0.9	0.9	0.5
Alzheimer’s Disease (in father)	0.8	0.8	1.3	-0.7	-1.0	-1.0	-0.6	-1.1	-0.7	-0.9	-0.8	-1.1	-0.7	-1.1	-1.1	-0.7	-0.9	-1.0
Systolic Blood Pressure	0.8	4.2	8.0	-2.1	-1.9	-1.9	-2.0	-1.9	-2.2	-2.3	-2.1	-2.0	-1.2	-2.8	-1.5	-1.9	-2.3	-2.2
Lung FEV1/FVC ratio	0.8	3.9	6.4	2.4	2.0	1.0	2.5	2.2	2.4	2.2	1.4	1.6	1.9	1.5	1.0	2.2	2.3	2.1
Medication for hormone replacement therapy	0.8	0.9	1.5	0.9	1.1	1.1	0.7	1.0	1.0	0.9	1.2	0.3	1.0	0.8	1.2	1.1	0.9	0.9
Fluid intelligence score	0.8	1.6	2.6	1.3	1.2	1.3	1.3	1.1	1.2	1.5	1.5	1.6	-0.4	1.3	1.1	0.9	1.5	1.3
Illnesses of siblings	0.8	1.1	2.4	-1.5	-1.5	-0.8	-0.9	-1.3	-1.3	-0.7	-1.0	-0.3	-1.1	-0.5	-1.5	-1.2	-0.7	-0.4
Neuroticism score	0.8	1.7	5.1	-1.3	-0.9	-2.3	-0.8	-1.1	-0.7	-2.0	-1.2	-0.2	-0.5	-2.2	-0.4	-0.9	-1.5	-1.5
Father’s age at death	0.8	1.1	2.3	0.8	1.3	1.2	0.7	1.4	1.5	1.3	0.9	0.3	1.2	0.5	1.1	1.2	0.9	0.9
Glaucoma (self-reported)	0.8	0.9	2.2	1.0	1.4	0.2	1.1	1.3	0.9	0.6	0.7	1.2	1.0	0.1	1.5	1.1	0.8	0.5
Medication: Omeprazole	0.8	0.9	3.1	0.5	0.9	0.1	1.0	0.9	0.7	0.7	0.5	1.8	1.2	0.6	0.9	0.8	1.3	1.4
Mean time to correctly identify matches	0.8	1.6	6.0	-0.6	-1.6	-2.3	0.7	-1.3	-1.2	-1.0	-1.5	-0.5	-1.0	0.2	-2.4	-0.9	-0.5	-0.4
Illnesses of siblings: Diabetes	0.8	1.0	1.7	1.3	1.2	0.7	1.0	1.2	1.2	0.9	0.8	0.4	1.3	0.4	1.0	1.2	0.8	0.8
Ever depressed for a whole week	0.8	1.0	3.0	-0.7	-0.6	-0.4	-1.3	-1.0	-1.0	-1.1	-0.4	0.5	-1.7	-1.2	-0.1	-1.4	-0.8	-1.0
Blood Platelet Count	0.7	8.2	13.2	-3.2	-3.1	-3.1	-2.0	-3.0	-3.1	-3.0	-2.9	-2.1	-2.2	-3.6	-3.0	-2.8	-2.7	-2.7
Hand grip strength (left)	0.7	1.9	5.0	-1.4	-1.2	0.2	-2.2	-1.5	-1.4	-1.2	-0.2	-1.3	-1.9	-1.0	-0.0	-1.5	-1.6	-1.6
Medication: Metformin	0.7	1.0	3.3	0.7	1.2	1.8	-0.1	0.9	0.9	0.7	1.3	0.5	0.6	0.9	1.8	0.8	0.4	0.3
Fed-up feelings	0.7	1.3	6.4	1.0	1.4	0.6	0.4	1.2	1.1	0.0	1.6	1.1	1.2	-0.3	2.5	1.2	0.4	0.2
Stomach or abdominal pain in last month	0.7	0.9	4.0	0.2	0.5	2.0	-0.7	0.0	0.3	0.4	1.8	0.2	-0.7	1.2	1.6	0.2	-0.1	-0.2
Financial difficulties in last 2 years	0.7	0.9	1.8	-0.7	-0.9	-1.2	-0.7	-0.9	-0.6	-1.4	-0.7	-1.3	-0.6	-1.1	-0.4	-0.6	-1.4	-1.3
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	2.3	-1.3	-1.4	-1.1	-0.9	-1.4	-1.2	-1.4	-1.0	-0.9	-1.4	-0.6	-0.9	-1.1	-1.5	-1.3
Medication: Seretide 50 evohaler	0.7	0.8	1.8	-1.1	-0.9	-0.4	-1.3	-0.9	-1.3	-0.9	-0.7	-0.4	-0.5	-0.5	-0.7	-1.0	-1.0	-1.1
Age at last live birth	0.7	1.1	3.4	-0.9	-1.3	-0.9	-0.3	-1.1	-1.2	-0.4	-1.2	-0.2	-1.6	0.7	-1.8	-1.2	-0.5	-0.1
Diabetes diagnosed by doctor	0.7	1.1	2.8	1.2	1.4	1.1	0.7	1.0	1.0	0.7	1.4	1.6	0.2	0.5	1.7	0.8	0.8	0.6
Eye problems/disorders: Cataract	0.7	0.8	3.2	-0.9	-0.4	-1.1	0.1	-0.2	-0.4	-0.3	-1.6	-1.8	-0.9	-0.4	-1.3	-0.7	-0.5	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.0	-1.0	-0.8	-0.5	-1.1	-0.8	-0.8	-0.9	-0.7	-1.4	-0.2	-1.0	-0.7	-0.6	-1.1	-1.1
Average weekly champagne plus white wine intake	0.7	1.0	2.1	0.5	0.5	1.5	0.6	0.9	0.7	1.4	0.9	0.2	1.1	1.4	0.4	1.0	1.1	1.4
Guilty feelings	0.7	1.1	2.1	-1.4	-0.9	-0.9	-1.4	-1.1	-1.0	-1.4	-0.8	0.0	-0.6	-1.1	-0.3	-1.1	-1.3	-1.1
Commuting to job workplace: Public transport	0.7	0.8	1.6	1.0	0.7	0.7	1.0	1.0	0.7	1.0	0.7	0.1	1.1	-0.1	0.7	1.1	1.1	1.3
Medication: Atorvastatin	0.7	0.9	2.0	1.3	0.8	1.1	0.4	0.6	0.8	0.6	1.4	0.9	0.8	0.8	1.4	0.9	0.8	0.6
Maternal smoking around birth	0.6	0.9	2.4	1.0	1.2	-0.7	1.6	1.1	1.1	0.2	0.3	1.0	0.9	1.0	0.8	1.1	0.7	0.3
Nervous feelings	0.6	1.1	4.8	-0.8	-0.8	-2.2	-0.1	-0.9	-0.7	-1.3	-1.5	0.4	-0.2	-1.6	-1.1	-0.8	-0.6	-0.5
Medication: Ramipril	0.6	0.7	2.5	1.2	0.8	-0.2	1.6	0.5	0.6	0.6	0.6	1.4	-0.4	1.0	0.2	0.5	1.0	0.7
Hair/balding pattern: Pattern 3	0.6	0.9	1.9	-0.8	-1.4	-0.7	-1.0	-1.2	-1.3	-0.8	-0.8	-0.3	-1.0	-0.2	-1.2	-1.1	-0.8	-0.6
Mouth/teeth dental problems: Dentures	0.6	1.1	2.7	0.8	1.1	0.0	1.2	1.2	1.6	0.6	0.8	1.2	1.2	-0.4	1.3	1.4	0.7	0.8
Length of working week for main job	0.6	0.7	1.7	-1.3	-0.7	-0.6	-1.2	-0.7	-0.5	-0.9	-0.7	-0.9	-0.4	-0.9	-0.1	-0.7	-1.0	-0.7
Blood clot in the leg (DVT)	0.6	0.7	2.1	-0.7	-1.3	0.1	-1.1	-0.8	-0.8	-0.4	-0.4	-1.4	0.6	-0.8	-1.2	-0.4	-0.8	-0.9
Birth weight	0.6	1.3	2.6	0.8	1.2	1.6	0.9	1.3	1.2	1.4	1.1	0.4	0.6	1.5	1.0	1.2	0.9	1.0
Heart disease (mother)	0.6	0.7	2.2	0.5	1.1	1.5	-0.4	0.8	0.5	0.7	1.0	1.1	0.4	0.9	1.3	0.4	0.6	0.4
Medication: Aspirin	0.6	0.7	1.3	-0.6	-0.7	-0.9	-1.1	-0.8	-0.7	-1.1	-1.0	-0.8	-0.3	-0.8	-0.6	-0.9	-1.1	-1.0
Commuting to job workplace: Walk	0.6	0.7	3.0	0.6	0.7	-0.6	1.7	0.8	0.5	0.7	-0.8	-0.5	0.6	0.1	-0.8	0.6	1.0	1.0
Medication for cholesterol	0.6	0.9	2.9	-0.9	-1.1	-1.7	-0.0	-0.8	-0.9	-1.0	-1.6	-0.3	-0.5	-0.3	-1.5	-0.8	-0.6	-0.7
Osteoporosis (self-reported)	0.6	0.7	1.8	-1.3	-0.9	-0.9	-0.8	-0.8	-0.9	-1.1	-0.8	-0.5	-0.3	-1.1	-0.4	-0.6	-0.9	-0.7
Medication: Aspirin	0.6	0.8	1.4	-0.5	-0.8	-1.0	-1.1	-0.8	-0.7	-1.2	-1.0	-0.9	-0.1	-0.9	-0.6	-0.9	-1.1	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.9	0.4	0.9	0.3	0.8	0.8	0.6	0.7	0.5	1.4	0.9	0.6	0.8	0.7	1.2	1.3
Pain experienced in last month	0.6	1.1	3.2	1.0	0.3	1.5	1.0	0.7	0.5	1.8	0.7	-0.1	0.5	1.4	-0.6	0.7	1.3	1.5
Alcohol drinker status: Previous	0.6	0.7	1.5	-0.7	-0.9	-0.2	-1.1	-0.8	-0.9	-0.9	-0.3	-0.5	-0.7	-1.2	-0.1	-0.6	-1.1	-1.2
Depression (Nagel 2018)	0.5	0.8	3.2	0.5	0.6	0.1	-0.3	0.6	0.7	-0.5	0.7	-0.5	1.5	-1.8	1.6	0.8	-0.1	-0.5
LDL Cholesterol	0.5	0.8	2.6	-0.3	-0.8	-1.2	0.0	-0.8	-0.9	-0.6	-1.4	-1.1	-0.7	0.2	-1.6	-0.9	-0.4	-0.5
Triglycerides	0.5	0.8	2.8	-0.7	-0.8	-0.1	-1.3	-1.2	-1.0	-0.9	-0.2	0.8	-1.7	0.2	-0.2	-1.3	-0.8	-0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.4	-0.6	-0.4	0.7	-1.5	-0.5	-0.8	-0.7	0.3	-0.8	-0.6	-1.0	0.6	-0.6	-0.9	-0.9
Ulcerative Colitis	0.5	0.8	2.7	-1.0	-0.6	-1.6	0.1	-0.7	-0.9	-1.0	-1.3	-0.9	-0.7	-0.3	-1.0	-0.7	-0.7	-0.6
Heel T-Score	0.5	4.0	10.3	2.4	2.4	-0.3	2.3	1.8	1.7	0.4	2.0	3.1	1.7	0.5	3.2	2.0	1.9	1.2
Type 2 Diabetes (T2D) (2018)	0.5	0.9	3.8	0.9	1.2	0.8	0.3	0.8	0.8	0.2	1.4	1.7	-0.1	0.4	2.0	0.5	0.5	0.2
Neuroticism	0.5	1.2	5.7	-0.9	-0.5	-2.4	-0.2	-0.5	-0.3	-1.8	-1.2	-0.3	0.3	-1.8	-0.1	-0.3	-1.2	-1.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	4.1	0.8	0.8	1.7	1.0	1.1	1.1	2.0	1.1	1.4	1.0	1.6	0.2	1.1	1.7	2.0
Noisy workplace	0.5	0.6	1.2	0.7	0.7	0.9	0.2	0.6	0.7	0.7	0.7	1.0	0.7	1.1	0.8	0.6	0.6	0.8
Hair/balding pattern: Pattern 4	0.5	1.1	3.2	-0.7	-0.5	-1.1	-1.1	-0.9	-0.9	-1.4	-0.9	-1.4	-0.6	-1.8	-0.2	-1.1	-1.0	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.4	1.2	0.7	0.9	1.1	0.6	0.8	1.0	0.7	-0.2	-0.1	1.2	0.1	0.6	0.8	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.6	0.5	0.9	0.4	0.7	0.9	1.0	0.9	0.2	1.3	0.7	0.4	0.2	0.7	0.7	0.9
Breast cancer (self-reported)	0.5	0.6	1.4	-1.2	-0.7	-1.0	-0.4	-0.4	-0.3	-0.6	-1.1	-0.9	-0.3	-1.1	-0.7	-0.4	-0.9	-0.6
Hearing aid user	0.5	0.6	2.4	-0.2	-0.9	-1.3	0.2	-0.9	-0.8	-0.5	-0.9	-0.3	-0.4	-0.2	-1.6	-0.8	-0.0	-0.0
Medication: Blood pressure	0.5	0.9	2.4	1.0	0.9	1.6	0.2	1.0	0.9	1.1	1.2	0.2	1.1	0.5	1.1	1.0	0.7	0.8
Ever smoked	0.5	0.8	3.7	0.6	0.5	1.2	-0.4	0.4	0.7	0.2	1.9	1.0	0.6	-0.1	1.9	0.7	0.3	0.1
Risk taking	0.5	0.8	2.0	-1.0	-1.2	0.3	-1.4	-1.0	-0.9	-0.2	-0.4	-0.6	-0.9	-0.2	-1.1	-1.0	-1.1	-0.9
Depressed Affect (Nagel 2018)	0.4	0.9	3.3	0.4	0.7	-0.8	0.5	0.8	0.9	-0.7	0.6	0.6	1.4	-1.8	1.6	1.0	-0.1	-0.4
Bipolar Disorder (2011)	0.4	0.4	1.7	0.6	-0.4	0.4	0.6	-0.1	0.0	0.9	-0.0	-0.5	-0.0	1.3	-1.3	0.2	0.6	0.7
Primary Biliary Cirrhosis	0.4	0.6	1.6	-0.9	-0.6	-1.2	-0.3	-0.4	-0.4	-0.6	-1.3	-0.9	-0.0	-1.3	-1.0	-0.5	-0.7	-0.6
Smoking Status	0.4	0.9	4.4	-0.3	0.0	0.1	-1.3	-0.3	-0.1	-1.2	1.1	0.3	-0.1	-1.4	2.1	-0.1	-0.9	-1.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.2	-0.0	0.5	1.2	-0.4	0.6	0.7	0.6	0.6	-0.4	1.5	0.4	0.6	0.7	0.1	0.3
Ever had hysterectomy (womb removed)	0.4	0.5	2.4	-0.1	0.4	0.4	-0.7	0.5	0.3	-0.2	0.5	0.2	1.1	-1.6	1.2	0.5	-0.2	-0.3
Supplements: Glucosamine	0.4	0.5	4.1	-0.2	0.5	-0.3	0.1	0.9	0.5	0.0	-0.7	-0.9	2.0	-0.1	0.1	0.7	-0.1	-0.2
Past tobacco smoking	0.4	0.8	5.0	-0.3	-0.6	-0.7	1.0	-0.1	-0.3	0.6	-1.5	-0.9	-0.4	0.4	-2.2	-0.2	0.3	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.2	0.2	0.9	0.2	-0.6	0.5	0.3	-0.7	0.7	0.7	0.6	-0.8	2.0	0.3	-0.3	-0.6
Hearing difficulty/problems with background noise	0.4	0.7	1.7	-0.6	-0.9	-0.7	-0.9	-1.3	-1.2	-1.3	-0.1	0.1	-0.8	-0.3	-0.2	-1.1	-0.6	-0.8
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.8	0.3	0.5	0.5	-0.3	0.1	-0.1	-0.2	0.9	1.7	-0.8	0.2	1.3	-0.2	0.2	-0.2
Pain all over the body in last month	0.4	0.4	1.1	-0.2	-0.4	-0.7	-0.7	-0.4	-0.4	-1.1	-0.3	-0.1	0.5	-1.0	0.2	-0.3	-0.8	-1.0
Diabetes (self-reported)	0.4	0.6	1.6	0.9	1.1	0.9	0.3	0.7	0.7	0.5	1.0	1.1	-0.0	-0.1	1.3	0.5	0.5	0.4
Medication: Simvastatin	0.4	0.6	1.9	0.9	0.9	-0.2	1.4	0.9	1.0	0.7	0.1	0.3	0.5	0.1	0.1	0.8	0.8	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.1	-0.3	-0.1	-1.0	0.6	-0.3	0.3	-0.2	-0.3	1.5	-1.5	-0.7	-0.6	-0.4	-0.2	-0.3
Birth weight of first child	0.4	0.7	2.8	0.2	0.3	1.4	-0.0	0.7	0.5	0.8	0.6	-1.3	1.7	1.1	0.3	1.0	0.3	0.3
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	0.9	-1.0	-0.9	-0.4	-0.9	-0.7	-0.8	-0.7	-0.7	-0.9	-0.3	-0.8	-0.7	-0.6	-0.9	-0.9
High blood pressure (siblings)	0.4	0.6	2.0	0.7	1.3	0.5	0.6	1.0	0.9	0.3	0.7	-0.1	0.8	-0.3	1.4	0.9	0.3	0.0
Number of children fathered	0.4	0.4	2.5	0.6	0.5	0.0	0.8	0.6	0.6	0.3	0.3	-0.7	1.6	0.0	0.3	1.0	0.5	0.4
Pulse rate, automated reading	0.4	1.4	7.1	1.2	1.5	0.1	0.2	0.7	0.6	-0.5	1.5	2.4	0.8	-0.5	2.7	0.5	0.8	0.2
Suffer from ‘nerves’	0.4	0.7	3.2	-1.0	-0.2	-1.3	-0.4	-0.2	-0.4	-1.1	-1.0	-0.1	0.2	-1.8	0.2	-0.3	-0.8	-0.5
Leg pain on walking	0.4	0.5	1.0	0.1	0.9	0.2	0.3	1.0	1.0	0.5	0.1	0.9	1.0	0.6	0.8	0.7	0.4	0.4
Loneliness, isolation	0.4	0.5	1.6	-0.5	-0.3	-0.8	-0.8	-0.6	-0.5	-1.2	-0.1	0.5	-0.5	-0.8	0.5	-0.6	-1.0	-1.1
High cholesterol (Self-reported)	0.4	0.8	1.8	1.1	0.9	1.2	0.5	0.7	0.8	0.8	1.3	0.7	-0.2	0.6	1.3	0.7	0.7	0.7
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.9	0.7	0.8	0.3	0.9	0.9	0.8	0.7	0.2	-0.2	0.8	-0.3	0.3	0.9	0.8	0.9
Bipolar Disorder (2018)	0.3	0.5	2.1	0.5	-0.4	-0.3	0.8	-0.2	-0.3	0.5	-0.6	-0.9	-0.1	1.3	-1.4	-0.2	0.8	0.8
Neuroticism (Nagel 2018)	0.3	0.7	1.9	0.3	0.6	-1.1	0.6	0.7	0.9	-0.5	0.1	1.0	1.2	-1.4	1.1	0.9	0.1	0.0
Major Depression (MDD)	0.3	0.4	2.3	0.2	0.2	0.4	-0.3	-0.4	-0.1	-0.1	0.7	1.5	-1.1	1.0	0.6	-0.4	0.2	0.1
HDL Cholesterol	0.3	0.4	2.3	-0.3	-0.4	-0.3	-0.7	-0.2	-0.4	-0.4	-0.5	-1.0	1.0	-1.5	-0.4	0.0	-0.4	-0.4
Angina	0.3	0.4	1.8	-0.6	-0.6	-0.6	-0.4	-0.6	-0.4	-0.4	-0.4	0.9	-1.4	-0.6	-0.6	-0.7	-0.6	-0.5
Diabetes (father)	0.3	0.3	0.7	0.6	0.8	0.6	0.1	0.7	0.6	0.5	0.1	-0.6	0.9	0.4	0.6	0.4	0.5	0.5
Diabetes (mother)	0.3	0.4	1.1	0.7	1.0	-0.2	0.9	0.6	0.4	0.2	0.3	1.0	-0.0	0.7	0.7	0.4	0.5	0.1
Severe depression (siblings)	0.3	0.3	1.3	-0.5	-0.5	0.3	-1.1	-0.7	-0.6	-0.7	0.2	-0.4	-0.1	-0.1	0.2	-0.5	-0.6	-0.8
Hand grip strength (right)	0.3	0.8	2.2	-0.7	-0.6	0.2	-1.4	-0.8	-0.8	-0.8	-0.1	-0.9	-1.5	-0.4	0.3	-0.9	-1.1	-1.1
Taking other prescription medications	0.3	0.4	1.5	-0.3	0.1	-0.6	-0.7	-0.0	-0.2	-1.1	0.0	-0.1	0.1	-1.2	1.1	-0.1	-0.7	-0.7
Qualifications: CSEs or equivalent	0.3	0.3	1.5	1.0	0.8	-0.6	1.2	0.6	0.8	0.1	0.1	0.3	-0.1	0.3	0.3	0.5	0.4	0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	0.5	0.8	0.1	0.6	0.5	0.5	0.4	0.3	1.1	0.9	0.8	0.3	0.4	0.9	0.5
Medication: Levothyroxine sodium	0.3	0.6	2.0	-0.7	-0.7	-0.7	-0.3	-1.0	-0.7	-0.9	-0.3	-0.3	-1.4	-0.2	-0.3	-0.8	-0.9	-0.8
Sitting height	0.3	2.4	4.9	-1.9	-2.0	-0.3	-2.2	-1.7	-1.7	-1.3	-0.9	-1.2	-1.1	-1.3	-1.2	-1.5	-1.9	-2.0
Chronic bronchitis/emphysema (father)	0.3	0.4	2.1	0.0	0.3	0.0	-0.4	-0.2	-0.1	-0.6	0.7	1.4	-0.5	-0.9	1.1	-0.2	-0.2	-0.7
Had other major operations	0.3	0.4	1.5	0.3	0.8	-0.1	0.6	0.6	0.6	-0.0	0.6	1.1	-0.1	-0.4	1.2	0.5	0.2	0.1
Pulse wave reflection index	0.3	0.4	1.2	0.5	0.4	0.1	1.1	0.7	0.7	0.8	0.1	-0.1	0.5	0.9	-0.0	0.8	0.6	0.6
Loud music exposure frequency	0.3	0.4	1.0	-0.4	-0.6	-1.0	-0.1	-0.7	-0.4	-0.7	-0.6	-0.7	-1.0	-0.4	-0.5	-0.6	-0.4	-0.5
Gout (self-reported)	0.3	0.5	1.4	0.7	0.8	0.7	0.4	0.3	0.5	0.3	1.2	0.9	-0.9	0.0	1.2	0.3	0.5	0.3
Exposure to tobacco smoke outside home	0.3	0.4	1.2	-0.3	-0.6	-1.1	0.0	-0.5	-0.5	-0.5	-0.8	-0.5	-0.5	-0.8	-0.9	-0.5	-0.3	-0.5
Worry too long after embarrassment	0.3	0.5	2.4	-0.7	-0.4	-1.5	0.0	-0.3	0.0	-0.8	-1.0	0.0	-0.6	-1.4	-0.4	-0.4	-0.6	-0.4
Age at first live birth	0.3	0.5	2.6	-0.5	-0.6	-0.9	-0.0	-0.3	-0.3	-0.1	-1.4	-0.6	-0.4	0.0	-1.6	-0.6	-0.2	0.1
Qualifications: College or University degree	0.3	1.0	3.0	0.5	0.3	1.6	0.6	0.7	0.7	1.7	0.5	-0.0	0.1	1.7	-0.3	0.6	1.2	1.7
Eye problems/disorders: None of the above	0.3	0.3	1.8	0.2	0.1	0.5	0.1	-0.1	0.2	0.0	1.2	1.4	-0.2	0.2	0.9	0.3	0.2	0.1
Angina (self-reported)	0.3	0.4	1.4	-0.5	-0.6	-0.6	-0.4	-0.5	-0.4	-0.4	-0.4	0.9	-1.2	-0.5	-0.5	-0.6	-0.6	-0.4
Number of full sisters	0.3	0.4	1.0	-0.8	-0.6	0.8	-1.0	-0.7	-0.5	-0.2	0.5	0.1	-0.9	-0.0	0.2	-0.4	-0.7	-0.6
Chest pain or discomfort	0.3	0.4	1.8	-0.3	0.2	0.9	-1.1	0.2	0.0	-0.2	0.7	0.4	0.3	-0.5	1.3	0.2	-0.5	-0.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.2	0.7	0.5	0.7	0.5	0.4	0.1	0.7	0.4	0.2	0.6	0.5	0.2	0.3	1.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	1.6	-1.3	-1.1	-0.9	-0.4	-0.7	-0.8	-0.5	-1.1	-0.6	-0.5	0.3	-1.2	-0.5	-0.9	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.6	0.1	0.0	-0.3	0.9	0.3	0.2	0.5	-0.2	0.6	0.3	1.3	-0.6	0.4	0.4	0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.8	0.3	0.4	1.4	-0.0	0.5	0.8	1.0	0.5	-0.3	-0.2	1.1	0.3	0.4	0.2	0.8
Smoking status: Current	0.3	0.4	2.1	0.1	0.1	0.5	-0.4	0.1	0.3	-0.2	1.2	1.2	0.2	-0.7	1.4	0.4	-0.0	-0.1
Miserableness	0.3	0.5	2.8	0.3	0.6	-0.4	-0.2	0.3	0.5	-0.9	0.7	0.4	0.2	-1.0	1.7	0.3	-0.5	-0.9
Illnesses of father: High blood pressure	0.3	0.4	1.0	0.4	0.8	0.0	0.9	0.8	1.0	0.6	0.2	0.1	0.3	-0.3	0.6	0.8	0.4	0.8
Irritability	0.3	0.5	1.0	1.0	0.9	-0.3	0.9	0.6	0.8	0.2	0.5	0.8	1.0	-0.1	0.6	0.6	0.9	0.5
Commuting to job workplace: Cycle	0.3	0.4	1.8	0.4	0.5	1.4	0.1	0.6	0.7	1.0	0.6	-0.6	-0.0	1.0	0.2	0.5	0.4	0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.0	0.5	0.6	0.6	0.4	0.7	0.9	0.5	0.9	0.7	0.6	0.3	1.0	0.8	0.5	0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.2	-0.4	-1.0	0.4	-0.8	-0.5	-0.5	-0.0	-0.1	-1.1	0.8	-0.5	-0.9	-0.1	-0.6	-0.5
Alzheimer’s Disease (including proxy)	0.2	0.2	0.8	-0.4	-0.6	-0.5	-0.2	-0.7	-0.5	-0.6	-0.0	0.3	-0.9	-0.1	-0.4	-0.4	-0.4	-0.4
Crohns Disease (2017)	0.2	0.4	1.5	0.3	0.3	1.2	0.1	0.6	0.5	0.6	1.0	-0.5	0.6	0.7	0.8	0.8	0.4	0.7
Prostate Cancer	0.2	0.2	1.1	-0.0	-0.3	-1.0	0.2	-0.3	-0.3	-0.5	-0.8	-0.4	-0.4	0.4	-0.7	-0.4	-0.3	-0.2
Neuroticism (2016)	0.2	0.3	1.0	0.0	0.5	-0.5	0.3	0.5	0.5	-0.5	0.2	0.2	0.7	-1.0	1.0	0.7	-0.4	-0.3
Height	0.2	3.1	13.0	-1.6	-2.6	-0.6	-1.5	-1.9	-1.4	-0.4	-1.9	-1.4	-1.3	0.1	-3.6	-1.8	-1.6	-1.6
Hair Pigment	0.2	6.6	10.7	-2.7	-2.9	-2.5	-2.2	-3.0	-2.5	-2.8	-2.1	-1.2	-3.3	-2.3	-2.0	-2.7	-2.9	-2.6
Current tobacco smoking	0.2	0.3	1.6	-0.1	-0.2	-0.0	-0.3	-0.2	0.1	-0.4	1.0	1.2	-0.3	-0.9	1.0	0.1	-0.2	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.9	-0.2	0.2	-0.7	-0.4	0.0	0.1	-0.9	-0.1	-0.3	0.6	-1.0	0.8	0.0	-0.5	-0.9
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	0.4	0.5	0.4	0.4	0.5	0.7	0.6	0.3	0.8	-0.1	0.1	0.4	0.5	0.3	0.7
Hair/balding pattern: Pattern 2	0.2	0.2	1.9	-0.4	-0.4	-0.1	-0.2	-0.1	0.0	-0.2	-0.5	-1.4	0.1	0.1	-0.4	0.0	-0.5	-0.3
Had menopause	0.2	0.2	0.9	0.4	-0.1	0.7	0.2	0.1	0.2	0.7	0.4	0.9	0.2	0.3	-0.2	0.3	0.3	0.6
Forced vital capacity (FVC)	0.2	0.7	2.7	-0.0	0.0	1.6	-0.1	0.4	0.4	1.4	0.8	0.7	0.5	1.0	-0.1	0.4	0.8	1.2
Mouth/teeth dental problems	0.2	0.3	1.3	0.5	0.1	0.8	0.2	0.1	-0.1	0.6	0.6	0.3	0.1	1.1	0.0	0.1	0.7	0.4
Heart attack	0.2	0.3	1.0	0.3	0.4	0.6	0.1	0.5	0.6	0.3	0.8	0.5	0.6	0.2	1.0	0.6	0.4	0.4
Worrier / anxious feelings	0.2	0.4	1.0	-0.3	-0.5	-1.0	-0.3	-0.7	-0.5	-0.7	-0.5	0.5	-0.8	-1.0	-0.5	-0.7	-0.2	-0.0
Pulse rate	0.2	0.3	1.4	0.1	0.5	0.1	-0.6	-0.1	-0.1	-0.5	0.5	1.2	-0.5	-0.6	1.2	-0.4	0.0	-0.2
Illnesses of mother	0.2	0.2	0.7	-0.2	-0.5	-0.6	0.6	-0.0	0.4	0.3	-0.6	-0.6	0.4	-0.3	-0.8	0.3	0.2	0.7
Pulse wave Arterial Stiffness index	0.2	0.2	0.7	0.5	0.4	-0.2	0.5	0.5	0.3	0.1	0.1	0.3	0.8	0.7	0.3	0.4	0.4	0.1
Standing height	0.2	2.2	5.6	-2.0	-2.2	-0.6	-1.5	-1.4	-1.3	-0.6	-1.6	-1.0	-1.1	-0.7	-2.4	-1.3	-1.6	-1.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.3	-0.9	-0.3	0.3	-0.9	0.1	-0.3	-0.2	-0.3	-1.1	1.1	-0.7	0.1	0.1	-0.5	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.9	4.5	-0.0	0.1	2.1	-0.4	0.5	0.5	1.5	1.1	0.6	0.7	1.1	0.3	0.6	0.7	1.1
Pulse wave peak to peak time	0.2	0.2	0.8	-0.6	-0.6	0.2	-0.6	-0.6	-0.3	-0.1	-0.1	-0.4	-0.9	-0.7	-0.4	-0.5	-0.5	-0.2
Health satisfaction	0.2	0.2	0.7	-0.3	-0.2	-0.7	-0.3	-0.4	-0.5	-0.9	-0.1	0.3	-0.7	-0.2	0.5	-0.4	-0.5	-0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	0.8	0.5	0.4	0.6	0.3	0.8	0.4	0.6	-0.3	-0.0	0.2	0.2	0.4	0.3	0.0
Medication: Allopurinol	0.2	0.3	1.9	0.2	-0.0	-0.3	0.1	-0.4	-0.2	-0.5	0.4	1.0	-1.4	-0.4	0.4	-0.4	-0.1	-0.3
Knee pain experienced in last month	0.2	0.3	1.4	-0.4	0.6	-0.8	0.1	0.6	0.6	-0.6	-0.3	0.0	1.2	-0.4	0.9	0.6	-0.3	-0.4
Smoking status: Previous	0.2	0.3	1.9	-0.0	0.4	0.3	-0.9	-0.1	0.1	-0.6	0.7	0.5	-0.1	-0.1	1.4	-0.3	-0.4	-0.9
Back pain experienced in last month	0.2	0.3	1.5	-0.2	-0.5	-1.2	0.0	-0.5	-0.6	-0.9	-0.3	0.9	-0.5	-0.3	0.0	-0.5	-0.3	-0.5
Osteoarthritis (self-reported)	0.2	0.3	0.7	0.6	0.8	0.5	0.1	0.5	0.7	0.4	0.6	0.6	0.9	0.6	0.7	0.4	0.5	0.0
Ever taken oral contraceptive pill	0.2	0.3	1.9	0.1	-0.3	0.2	0.1	-0.3	-0.2	0.2	-0.1	-1.4	0.1	1.1	-0.7	-0.2	0.3	0.4
Unable to work because of sickness or disability	0.2	0.3	1.0	0.5	0.6	0.5	0.2	0.4	0.4	0.2	0.8	1.0	0.7	0.4	0.7	0.4	0.4	0.2
Alzheimer’s Disease (in mother)	0.1	0.2	0.5	-0.4	-0.6	-0.4	-0.2	-0.6	-0.4	-0.4	-0.1	-0.0	-0.7	0.1	-0.4	-0.4	-0.3	-0.2
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	-0.1	0.2	0.6	-0.1	0.3	0.1	0.1	0.5	-0.6	0.6	0.7	0.6	0.5	0.2	0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.9	0.5	0.2	0.4	0.9	0.3	0.4	0.7	0.5	0.3	-0.8	1.0	-0.1	0.2	0.6	0.5
Breast Cancer	0.1	0.2	0.9	0.2	-0.1	0.6	-0.5	-0.3	-0.1	-0.0	0.4	-0.9	-0.9	-0.6	0.1	-0.3	-0.4	-0.1
Body Mass Index (BMI) (2010)	0.1	0.1	0.5	0.2	-0.2	-0.4	0.7	-0.2	-0.1	0.1	0.0	0.0	-0.4	0.1	-0.7	-0.0	0.1	0.1
Crohns Disease (2012)	0.1	0.2	0.6	-0.1	-0.1	0.8	-0.0	-0.1	0.1	0.3	0.8	-0.3	-0.8	0.2	0.2	0.2	-0.0	0.3
Waist Hip Ratio (WHR)	0.1	0.4	2.2	0.2	0.3	-0.6	0.5	0.1	0.1	-0.5	0.6	1.5	-0.3	-0.6	1.1	0.2	0.3	0.3
Cardiovascular Disease	0.1	0.3	1.0	0.8	0.4	0.5	0.5	0.3	0.3	0.5	0.7	0.2	0.3	1.0	0.4	0.4	0.7	0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.1	0.2	0.4	-0.2	-0.2	0.2	0.3	-0.5	0.4	0.1	0.2	-0.5	1.0	0.2	-0.1	-0.5
Systolic blood pressure, automated reading	0.1	0.3	1.4	0.0	0.3	-1.0	0.4	0.1	-0.0	-0.5	-0.8	-0.6	0.6	-1.2	-0.1	0.1	-0.3	-0.5
Time employed in main current job	0.1	0.1	1.1	0.2	-0.1	-1.1	0.6	-0.1	0.0	-0.3	-0.3	-0.1	0.2	-0.1	-0.3	0.1	0.0	-0.2
Medication: Cholesterol lowering	0.1	0.1	0.4	0.3	-0.2	-0.4	0.3	-0.3	0.1	-0.1	-0.1	0.6	-0.5	-0.1	-0.4	-0.2	0.1	0.1
Medication: Amlodipine	0.1	0.2	1.0	0.1	-0.3	-0.1	-0.3	-0.6	-0.6	-0.5	0.1	-0.1	-1.0	-0.3	-0.2	-0.7	-0.2	-0.5
Medication: Blood pressure	0.1	0.1	0.3	0.6	0.3	-0.2	0.5	-0.1	0.2	-0.0	0.3	0.5	-0.5	0.2	-0.1	-0.1	0.2	-0.2
Comparative height size at age 10	0.1	0.5	1.1	-0.6	-1.0	-0.3	-0.9	-0.9	-0.8	-0.4	-0.6	-0.1	-0.7	-0.0	-1.0	-1.0	-0.7	-0.8
Illnesses of father: None of the above (group 1)	0.1	0.1	0.4	0.3	-0.1	-0.0	0.4	-0.0	-0.0	0.2	-0.1	-0.3	0.1	0.6	-0.5	0.0	0.2	0.0
Number of self-reported non-cancer illnesses	0.1	0.1	0.5	-0.3	-0.0	-0.5	-0.1	-0.1	-0.2	-0.7	0.1	0.6	-0.1	-0.5	0.6	0.0	-0.4	-0.3
Mother’s age at death	0.1	0.2	0.6	0.2	0.1	-0.2	0.8	0.2	0.5	0.4	-0.3	-0.5	-0.5	0.4	-0.6	0.2	-0.1	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	1.0	0.3	0.3	-0.3	0.6	0.3	0.2	0.1	0.1	1.0	-0.1	-0.0	0.3	0.3	0.2	0.2
Medication: Lisinopril	0.1	0.2	0.8	-0.4	-0.3	0.3	-0.8	-0.2	-0.1	-0.3	-0.1	-0.7	-0.4	-0.9	0.1	-0.3	-0.5	-0.3
Average weekly beer plus cider intake	0.1	0.2	0.5	-0.3	-0.4	-0.7	0.1	-0.4	-0.0	-0.5	-0.1	0.0	-0.5	-0.2	0.1	0.1	-0.6	-0.6
Diastolic blood pressure, automated reading	0.1	0.4	2.0	-0.1	-0.0	-1.1	-0.1	-0.4	-0.5	-0.9	-0.7	-0.4	-0.1	-1.4	-0.1	-0.5	-0.5	-0.9
Myopia	0.1	0.2	0.6	0.1	0.3	0.5	-0.5	-0.0	-0.1	-0.2	0.5	0.2	-0.8	0.1	0.8	-0.3	-0.2	-0.3
Ulcerative Colitis (UC)	0.0	0.1	0.4	-0.3	-0.2	-0.1	-0.3	-0.4	-0.5	-0.4	-0.1	-0.4	-0.1	0.6	-0.0	-0.3	-0.1	-0.2
Tanning	0.0	0.4	1.1	-0.4	-0.6	-0.7	-0.5	-0.8	-0.7	-0.6	-0.3	1.0	0.1	-0.4	-0.7	-0.8	-0.1	-0.3
High blood pressure	0.0	0.0	0.2	0.3	0.2	0.1	0.2	-0.2	-0.0	0.0	0.2	0.1	-0.4	0.0	-0.3	-0.2	0.1	-0.0
Falls in the last year	0.0	0.1	0.2	0.3	-0.1	0.4	-0.4	-0.2	-0.1	0.1	0.2	0.4	-0.2	0.0	-0.0	-0.3	0.0	0.1
Hypertension (Self-reported)	0.0	0.1	0.3	0.6	0.5	0.4	0.2	0.0	0.2	0.3	0.5	0.4	-0.2	0.2	0.2	0.0	0.3	0.2
Wears glasses or contact lenses	0.0	0.1	0.2	0.2	0.3	-0.2	0.2	0.3	0.4	-0.0	-0.2	-0.4	-0.1	-0.1	0.2	0.2	-0.0	0.0
Medication: Bendroflumethiazide	0.0	0.0	0.1	-0.1	0.1	-0.4	0.1	-0.1	0.0	-0.2	0.1	0.2	0.3	-0.1	0.1	0.0	0.1	-0.0
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.3	-0.4	-0.0	0.2	-0.2	0.2	-0.0	0.0	0.1	-0.0	0.1	-0.1	0.5	0.2	-0.1	0.0

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